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Volumn 13, Issue 9, 2011, Pages 1397-1409

Highly co-ordinated var gene expression and switching in clinical Plasmodium falciparum isolates from non-immune malaria patients

Author keywords

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Indexed keywords

ERYTHROCYTE MEMBRANE PROTEIN 1;

EID: 80051804179     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2011.01629.x     Document Type: Article
Times cited : (35)

References (48)
  • 1
    • 70449393982 scopus 로고    scopus 로고
    • Absence of erythrocyte sequestration and lack of multicopy gene family expression in Plasmodium falciparum from a splenectomized malaria patient
    • Bachmann, A., Esser, C., Petter, M., Predehl, S., von Kalckreuth, V., Schmiedel, S., etal. (2009) Absence of erythrocyte sequestration and lack of multicopy gene family expression in Plasmodium falciparum from a splenectomized malaria patient. PLoS ONE 4: e7459.
    • (2009) PLoS ONE , vol.4
    • Bachmann, A.1    Esser, C.2    Petter, M.3    Predehl, S.4    von Kalckreuth, V.5    Schmiedel, S.6
  • 2
    • 0029052741 scopus 로고
    • Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes
    • Baruch, D.I., Pasloske, B.L., Singh, H.B., Bi, X., Ma, X.C., Feldman, M., etal. (1995) Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes. Cell 82: 77-87.
    • (1995) Cell , vol.82 , pp. 77-87
    • Baruch, D.I.1    Pasloske, B.L.2    Singh, H.B.3    Bi, X.4    Ma, X.C.5    Feldman, M.6
  • 4
    • 33745624376 scopus 로고    scopus 로고
    • Plasmodium falciparum variant surface antigen expression patterns during malaria
    • Bull, P.C., Berriman, M., Kyes, S., Quail, M.A., Hall, N., Kortok, M.M., etal. (2005) Plasmodium falciparum variant surface antigen expression patterns during malaria. PLoS Pathog 1: e26.
    • (2005) PLoS Pathog , vol.1
    • Bull, P.C.1    Berriman, M.2    Kyes, S.3    Quail, M.A.4    Hall, N.5    Kortok, M.M.6
  • 5
    • 0034043778 scopus 로고    scopus 로고
    • Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis
    • Castresana, J. (2000) Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. Mol Biol Evol 17: 540-552.
    • (2000) Mol Biol Evol , vol.17 , pp. 540-552
    • Castresana, J.1
  • 6
    • 70349243273 scopus 로고    scopus 로고
    • Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains
    • Cham, G.K., Turner, L., Lusingu, J., Vestergaard, L., Mmbando, B.P., Kurtis, J.D., etal. (2009) Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains. J Immunol 183: 3356-3363.
    • (2009) J Immunol , vol.183 , pp. 3356-3363
    • Cham, G.K.1    Turner, L.2    Lusingu, J.3    Vestergaard, L.4    Mmbando, B.P.5    Kurtis, J.D.6
  • 7
    • 78049422784 scopus 로고    scopus 로고
    • Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
    • Cham, G.K., Turner, L., Kurtis, J.D., Mutabingwa, T., Fried, M., Jensen, A.T., etal. (2010) Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children. Infect Immun 78: 4653-4659.
    • (2010) Infect Immun , vol.78 , pp. 4653-4659
    • Cham, G.K.1    Turner, L.2    Kurtis, J.D.3    Mutabingwa, T.4    Fried, M.5    Jensen, A.T.6
  • 8
    • 34447095947 scopus 로고    scopus 로고
    • Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
    • Dahlback, M., Lavstsen, T., Salanti, A., Hviid, L., Arnot, D.E., Theander, T.G., and Nielsen, M.A. (2007) Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites. Malar J 6: 78.
    • (2007) Malar J , vol.6 , pp. 78
    • Dahlback, M.1    Lavstsen, T.2    Salanti, A.3    Hviid, L.4    Arnot, D.E.5    Theander, T.G.6    Nielsen, M.A.7
  • 9
    • 17044371098 scopus 로고    scopus 로고
    • Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype
    • Duffy, M.F., Byrne, T.J., Elliott, S.R., Wilson, D.W., Rogerson, S.J., Beeson, J.G., etal. (2005) Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype. Mol Microbiol 56: 774-788.
    • (2005) Mol Microbiol , vol.56 , pp. 774-788
    • Duffy, M.F.1    Byrne, T.J.2    Elliott, S.R.3    Wilson, D.W.4    Rogerson, S.J.5    Beeson, J.G.6
  • 10
    • 65649152946 scopus 로고    scopus 로고
    • Ectopic recombination of a malaria var gene during mitosis associated with an altered var switch rate
    • Duffy, M.F., Byrne, T.J., Carret, C., Ivens, A., and Brown, G.V. (2009) Ectopic recombination of a malaria var gene during mitosis associated with an altered var switch rate. J Mol Biol 389: 453-469.
    • (2009) J Mol Biol , vol.389 , pp. 453-469
    • Duffy, M.F.1    Byrne, T.J.2    Carret, C.3    Ivens, A.4    Brown, G.V.5
  • 11
    • 34250009026 scopus 로고    scopus 로고
    • Variable switching rates of malaria virulence genes are associated with chromosomal position
    • Frank, M., Dzikowski, R., Amulic, B., and Deitsch, K. (2007) Variable switching rates of malaria virulence genes are associated with chromosomal position. Mol Microbiol 64: 1486-1498.
    • (2007) Mol Microbiol , vol.64 , pp. 1486-1498
    • Frank, M.1    Dzikowski, R.2    Amulic, B.3    Deitsch, K.4
  • 12
    • 0038404589 scopus 로고    scopus 로고
    • Switching rates of Plasmodium falciparum var genes: faster than we thought?
    • Gatton, M.L., Peters, J.M., Fowler, E.V., and Cheng, Q. (2003) Switching rates of Plasmodium falciparum var genes: faster than we thought? Trends Parasitol 19: 202-208.
    • (2003) Trends Parasitol , vol.19 , pp. 202-208
    • Gatton, M.L.1    Peters, J.M.2    Fowler, E.V.3    Cheng, Q.4
  • 14
    • 2442493112 scopus 로고    scopus 로고
    • Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
    • Jensen, A.T., Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, T., Chiucchiuini, A., etal. (2004) Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes. J Exp Med 199: 1179-1190.
    • (2004) J Exp Med , vol.199 , pp. 1179-1190
    • Jensen, A.T.1    Magistrado, P.2    Sharp, S.3    Joergensen, L.4    Lavstsen, T.5    Chiucchiuini, A.6
  • 15
    • 2442695102 scopus 로고    scopus 로고
    • Longitudinal assessment of Plasmodium falciparum var gene transcription in naturally infected asymptomatic children in Papua New Guinea
    • Kaestli, M., Cortes, A., Lagog, M., Ott, M., and Beck, H.P. (2004) Longitudinal assessment of Plasmodium falciparum var gene transcription in naturally infected asymptomatic children in Papua New Guinea. J Infect Dis 189: 1942-1951.
    • (2004) J Infect Dis , vol.189 , pp. 1942-1951
    • Kaestli, M.1    Cortes, A.2    Lagog, M.3    Ott, M.4    Beck, H.P.5
  • 16
    • 33646931473 scopus 로고    scopus 로고
    • Virulence of malaria is associated with differential expression of Plasmodium falciparum var gene subgroups in a case-control study
    • Kaestli, M., Cockburn, I.A., Cortes, A., Baea, K., Rowe, J.A., and Beck, H.P. (2006) Virulence of malaria is associated with differential expression of Plasmodium falciparum var gene subgroups in a case-control study. J Infect Dis 193: 1567-1574.
    • (2006) J Infect Dis , vol.193 , pp. 1567-1574
    • Kaestli, M.1    Cockburn, I.A.2    Cortes, A.3    Baea, K.4    Rowe, J.A.5    Beck, H.P.6
  • 17
    • 45949107473 scopus 로고    scopus 로고
    • Recent developments in the MAFFT multiple sequence alignment program
    • Katoh, K., and Toh, H. (2008) Recent developments in the MAFFT multiple sequence alignment program. Brief Bioinform 9: 286-298.
    • (2008) Brief Bioinform , vol.9 , pp. 286-298
    • Katoh, K.1    Toh, H.2
  • 18
    • 0037100671 scopus 로고    scopus 로고
    • MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform
    • Katoh, K., Misawa, K., Kuma, K., and Miyata, T. (2002) MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. Nucleic Acids Res 30: 3059-3066.
    • (2002) Nucleic Acids Res , vol.30 , pp. 3059-3066
    • Katoh, K.1    Misawa, K.2    Kuma, K.3    Miyata, T.4
  • 19
    • 0347517765 scopus 로고    scopus 로고
    • Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family
    • Kraemer, S.M., and Smith, J.D. (2003) Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family. Mol Microbiol 50: 1527-1538.
    • (2003) Mol Microbiol , vol.50 , pp. 1527-1538
    • Kraemer, S.M.1    Smith, J.D.2
  • 20
    • 33847643223 scopus 로고    scopus 로고
    • Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates
    • Kraemer, S.M., Kyes, S.A., Aggarwal, G., Springer, A.L., Nelson, S.O., Christodoulou, Z., etal. (2007) Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates. BMC Genomics 8: 45.
    • (2007) BMC Genomics , vol.8 , pp. 45
    • Kraemer, S.M.1    Kyes, S.A.2    Aggarwal, G.3    Springer, A.L.4    Nelson, S.O.5    Christodoulou, Z.6
  • 21
    • 0034780523 scopus 로고    scopus 로고
    • Antigenic variation at the infected red cell surface in malaria
    • Kyes, S., Horrocks, P., and Newbold, C. (2001) Antigenic variation at the infected red cell surface in malaria. Annu Rev Microbiol 55: 673-707.
    • (2001) Annu Rev Microbiol , vol.55 , pp. 673-707
    • Kyes, S.1    Horrocks, P.2    Newbold, C.3
  • 22
    • 34748900529 scopus 로고    scopus 로고
    • Antigenic variation in Plasmodium falciparum: gene organization and regulation of the var multigene family
    • Kyes, S.A., Kraemer, S.M., and Smith, J.D. (2007) Antigenic variation in Plasmodium falciparum: gene organization and regulation of the var multigene family. Eukaryot Cell 6: 1511-1520.
    • (2007) Eukaryot Cell , vol.6 , pp. 1511-1520
    • Kyes, S.A.1    Kraemer, S.M.2    Smith, J.D.3
  • 23
    • 0018704491 scopus 로고
    • Synchronization of Plasmodium falciparum erythrocytic stages in culture
    • Lambros, C., and Vanderberg, J.P. (1979) Synchronization of Plasmodium falciparum erythrocytic stages in culture. J Parasitol 65: 418-420.
    • (1979) J Parasitol , vol.65 , pp. 418-420
    • Lambros, C.1    Vanderberg, J.P.2
  • 24
    • 3042642153 scopus 로고    scopus 로고
    • Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions
    • Lavstsen, T., Salanti, A., Jensen, A.T., Arnot, D.E., and Theander, T.G. (2003) Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions. Malar J 2: 27.
    • (2003) Malar J , vol.2 , pp. 27
    • Lavstsen, T.1    Salanti, A.2    Jensen, A.T.3    Arnot, D.E.4    Theander, T.G.5
  • 25
    • 0028129356 scopus 로고
    • Malaria pathogenesis
    • Miller, L.H., Good, M.F., and Milon, G. (1994) Malaria pathogenesis. Science 264: 1878-1883.
    • (1994) Science , vol.264 , pp. 1878-1883
    • Miller, L.H.1    Good, M.F.2    Milon, G.3
  • 27
    • 44349118501 scopus 로고    scopus 로고
    • Default Pathway of var2csa switching and translational repression in Plasmodium falciparum
    • Mok, B.W., Ribacke, U., Rasti, N., Kironde, F., Chen, Q., Nilsson, P., and Wahlgren, M. (2008) Default Pathway of var2csa switching and translational repression in Plasmodium falciparum. PLoS ONE 3: e1982.
    • (2008) PLoS ONE , vol.3
    • Mok, B.W.1    Ribacke, U.2    Rasti, N.3    Kironde, F.4    Chen, Q.5    Nilsson, P.6    Wahlgren, M.7
  • 28
    • 0036196193 scopus 로고    scopus 로고
    • The Plasmodium falciparum var gene switching rate, switching mechanism and patterns of parasite recrudescence described by mathematical modelling
    • Paget-McNicol, S., Gatton, M., Hastings, I., and Saul, A. (2002) The Plasmodium falciparum var gene switching rate, switching mechanism and patterns of parasite recrudescence described by mathematical modelling. Parasitology 124: 225-235.
    • (2002) Parasitology , vol.124 , pp. 225-235
    • Paget-McNicol, S.1    Gatton, M.2    Hastings, I.3    Saul, A.4
  • 29
    • 0036678157 scopus 로고    scopus 로고
    • High diversity and rapid changeover of expressed var genes during the acute phase of Plasmodium falciparum infections in human volunteers
    • Peters, J., Fowler, E., Gatton, M., Chen, N., Saul, A., and Cheng, Q. (2002) High diversity and rapid changeover of expressed var genes during the acute phase of Plasmodium falciparum infections in human volunteers. Proc Natl Acad Sci USA 99: 10689-10694.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10689-10694
    • Peters, J.1    Fowler, E.2    Gatton, M.3    Chen, N.4    Saul, A.5    Cheng, Q.6
  • 30
    • 33847039605 scopus 로고    scopus 로고
    • Differential changes in Plasmodium falciparum var transcription during adaptation to culture
    • Peters, J.M., Fowler, E.V., Krause, D.R., Cheng, Q., and Gatton, M.L. (2007) Differential changes in Plasmodium falciparum var transcription during adaptation to culture. J Infect Dis 195: 748-755.
    • (2007) J Infect Dis , vol.195 , pp. 748-755
    • Peters, J.M.1    Fowler, E.V.2    Krause, D.R.3    Cheng, Q.4    Gatton, M.L.5
  • 31
    • 78049432071 scopus 로고    scopus 로고
    • Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes - divide and conquer
    • Rask, T.S., Hansen, D.A., Theander, T.G., Gorm Pedersen, A., and Lavstsen, T. (2010) Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes - divide and conquer. PLoS Comput Biol 6: e1000933.
    • (2010) PLoS Comput Biol , vol.6
    • Rask, T.S.1    Hansen, D.A.2    Theander, T.G.3    Gorm Pedersen, A.4    Lavstsen, T.5
  • 32
    • 79953288741 scopus 로고    scopus 로고
    • Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern
    • Recker, M., Buckee, C.O., Serazin, A., Kys, S., Pinches, R., Zóe, C., etal. (2011) Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern. PLoS Pathogens 3: e1001306.
    • (2011) PLoS Pathogens , vol.3
    • Recker, M.1    Buckee, C.O.2    Serazin, A.3    Kys, S.4    Pinches, R.5    Zóe, C.6
  • 33
    • 0030449667 scopus 로고    scopus 로고
    • Extensive genetic diversity of Plasmodium falciparum isolates collected from patients with severe malaria in Dakar, Senegal
    • Robert, F., Ntoumi, F., Angel, G., Candito, D., Rogier, C., Fandeur, T., etal. (1996) Extensive genetic diversity of Plasmodium falciparum isolates collected from patients with severe malaria in Dakar, Senegal. Trans R Soc Trop Med Hyg 90: 704-711.
    • (1996) Trans R Soc Trop Med Hyg , vol.90 , pp. 704-711
    • Robert, F.1    Ntoumi, F.2    Angel, G.3    Candito, D.4    Rogier, C.5    Fandeur, T.6
  • 35
    • 0038046769 scopus 로고    scopus 로고
    • Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria
    • Salanti, A., Staalsoe, T., Lavstsen, T., Jensen, A.T., Sowa, M.P., Arnot, D.E., etal. (2003) Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria. Mol Microbiol 49: 179-191.
    • (2003) Mol Microbiol , vol.49 , pp. 179-191
    • Salanti, A.1    Staalsoe, T.2    Lavstsen, T.3    Jensen, A.T.4    Sowa, M.P.5    Arnot, D.E.6
  • 36
    • 0032530397 scopus 로고    scopus 로고
    • Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum
    • Scherf, A., Hernandez-Rivas, R., Buffet, P., Bottius, E., Benatar, C., Pouvelle, B., etal. (1998) Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum. EMBO J 17: 5418-5426.
    • (1998) EMBO J , vol.17 , pp. 5418-5426
    • Scherf, A.1    Hernandez-Rivas, R.2    Buffet, P.3    Bottius, E.4    Benatar, C.5    Pouvelle, B.6
  • 38
    • 33747371424 scopus 로고    scopus 로고
    • Programmed transcription of the var gene family, but not of stevor, in Plasmodium falciparum gametocytes
    • Sharp, S., Lavstsen, T., Fivelman, Q.L., Saeed, M., McRobert, L., Templeton, T.J., etal. (2006) Programmed transcription of the var gene family, but not of stevor, in Plasmodium falciparum gametocytes. Eukaryot Cell 5: 1206-1214.
    • (2006) Eukaryot Cell , vol.5 , pp. 1206-1214
    • Sharp, S.1    Lavstsen, T.2    Fivelman, Q.L.3    Saeed, M.4    McRobert, L.5    Templeton, T.J.6
  • 39
    • 0028982168 scopus 로고
    • Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes
    • Smith, J.D., Chitnis, C.E., Craig, A.G., Roberts, D.J., Hudson-Taylor, D.E., Peterson, D.S., etal. (1995) Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes. Cell 82: 101-110.
    • (1995) Cell , vol.82 , pp. 101-110
    • Smith, J.D.1    Chitnis, C.E.2    Craig, A.G.3    Roberts, D.J.4    Hudson-Taylor, D.E.5    Peterson, D.S.6
  • 40
    • 0033727467 scopus 로고    scopus 로고
    • Classification of adhesive domains in the Plasmodium falciparum erythrocyte membrane protein 1 family
    • Smith, J.D., Subramanian, G., Gamain, B., Baruch, D.I., and Miller, L.H. (2000) Classification of adhesive domains in the Plasmodium falciparum erythrocyte membrane protein 1 family. Mol Biochem Parasitol 110: 293-310.
    • (2000) Mol Biochem Parasitol , vol.110 , pp. 293-310
    • Smith, J.D.1    Subramanian, G.2    Gamain, B.3    Baruch, D.I.4    Miller, L.H.5
  • 41
    • 0036721548 scopus 로고    scopus 로고
    • In vivo switching between variant surface antigens in human Plasmodium falciparum infection
    • Staalsoe, T., Hamad, A.A., Hviid, L., Elhassan, I.M., Arnot, D.E., and Theander, T.G. (2002) In vivo switching between variant surface antigens in human Plasmodium falciparum infection. J Infect Dis 186: 719-722.
    • (2002) J Infect Dis , vol.186 , pp. 719-722
    • Staalsoe, T.1    Hamad, A.A.2    Hviid, L.3    Elhassan, I.M.4    Arnot, D.E.5    Theander, T.G.6
  • 42
    • 33750403801 scopus 로고    scopus 로고
    • RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models
    • Stamatakis, A. (2006) RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics 22: 2688-2690.
    • (2006) Bioinformatics , vol.22 , pp. 2688-2690
    • Stamatakis, A.1
  • 43
    • 0029070914 scopus 로고
    • The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes
    • Su, X.Z., Heatwole, V.M., Wertheimer, S.P., Guinet, F., Herrfeldt, J.A., Peterson, D.S., etal. (1995) The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes. Cell 82: 89-100.
    • (1995) Cell , vol.82 , pp. 89-100
    • Su, X.Z.1    Heatwole, V.M.2    Wertheimer, S.P.3    Guinet, F.4    Herrfeldt, J.A.5    Peterson, D.S.6
  • 44
    • 22244446220 scopus 로고    scopus 로고
    • Human malaria parasites in continuous culture. 1976
    • Trager, W., and Jensen, J.B. (2005) Human malaria parasites in continuous culture. 1976. J Parasitol 91: 484-486.
    • (2005) J Parasitol , vol.91 , pp. 484-486
    • Trager, W.1    Jensen, J.B.2
  • 45
    • 0021028710 scopus 로고
    • Plasmodium falciparum: effect of time in continuous culture on binding to human endothelial cells and amelanotic melanoma cells
    • Udeinya, I.J., Graves, P.M., Carter, R., Aikawa, M., and Miller, L.H. (1983) Plasmodium falciparum: effect of time in continuous culture on binding to human endothelial cells and amelanotic melanoma cells. Exp Parasitol 56: 207-214.
    • (1983) Exp Parasitol , vol.56 , pp. 207-214
    • Udeinya, I.J.1    Graves, P.M.2    Carter, R.3    Aikawa, M.4    Miller, L.H.5
  • 46
    • 33644551229 scopus 로고    scopus 로고
    • A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria
    • Voss, T.S., Healer, J., Marty, A.J., Duffy, M.F., Thompson, J.K., Beeson, J.G., etal. (2006) A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria. Nature 439: 1004-1008.
    • (2006) Nature , vol.439 , pp. 1004-1008
    • Voss, T.S.1    Healer, J.2    Marty, A.J.3    Duffy, M.F.4    Thompson, J.K.5    Beeson, J.G.6
  • 47
    • 70349795728 scopus 로고    scopus 로고
    • The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer
    • Wang, C.W., Hermsen, C.C., Sauerwein, R.W., Arnot, D.E., Theander, T.G., and Lavstsen, T. (2009) The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer. Parasitol Int 58: 478-480.
    • (2009) Parasitol Int , vol.58 , pp. 478-480
    • Wang, C.W.1    Hermsen, C.C.2    Sauerwein, R.W.3    Arnot, D.E.4    Theander, T.G.5    Lavstsen, T.6


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