Rational design of SAM analogues targeting SAM-II riboswitch aptamer

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 17, 2011, Pages 5071-5074

  Ham, Young Wan ^a   Humphreys, Darin J ^a   Choi, Susie ^a   Dayton, Daniel L ^a  

^a Brigham Young University   (United States)

Author keywords

Metabolite analogue; S Adenosylmethionine (SAM); SAM II riboswitch

Indexed keywords

APTAMER; BACTERIAL RNA; MESSENGER RNA; S ADENOSYLMETHIONINE;

5' UNTRANSLATED REGION; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CRYSTAL STRUCTURE; DRUG DESIGN; FLUORESCENCE; GENE EXPRESSION; RIBOSWITCH;

CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; MOLECULAR STRUCTURE; S-ADENOSYLMETHIONINE;

BACTERIA (MICROORGANISMS);

EID: 80051797079     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.033     Document Type: Article

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