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Volumn 10, Issue 2, 2011, Pages 208-217

Distinct neurochemical profiles of spinocerebellar ataxias 1, 2, 6, and cerebellar multiple system atrophy

Author keywords

Ataxia; Magnetic resonance spectroscopy; Multiple system atrophy; Neurochemical profile; SCA

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ASCORBIC ACID; CREATININE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLYCEROPHOSPHORYLCHOLINE; INOSITOL; LACTIC ACID; N ACETYLASPARTIC ACID; N ACETYLASPARTYLGLUTAMIC ACID; PHOSPHORYLCHOLINE; SCYLLO INOSITOL; TAURINE; UNCLASSIFIED DRUG;

EID: 80051795157     PISSN: 14734222     EISSN: 14734230     Source Type: Journal    
DOI: 10.1007/s12311-010-0213-6     Document Type: Article
Times cited : (68)

References (40)
  • 1
    • 54049124218 scopus 로고    scopus 로고
    • Spinocerebellar ataxia types 1, 2, 3, and 6: Disease severity and nonataxia symptoms
    • Schmitz-Hübsch T, Coudert M, Bauer P, Giunti P, Globas C, Baliko L, et al. Spinocerebellar ataxia types 1, 2, 3, and 6: disease severity and nonataxia symptoms. Neurology. 2008;71(13):982-9.
    • (2008) Neurology. , vol.71 , Issue.13 , pp. 982-989
    • Schmitz-Hübsch, T.1    Coudert, M.2    Bauer, P.3    Giunti, P.4    Globas, C.5    Baliko, L.6
  • 2
    • 11144356369 scopus 로고    scopus 로고
    • Autosomal dominant cerebellar ataxias: Clinical features, genetics, and pathogenesis
    • DOI 10.1016/S1474-4422(04)00737-9, PII S1474442204007379
    • Schöls L, Bauer P, Schmidt T, Schulte T, Riess O. Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis. Lancet Neurol. 2004;3(5):291-304. (Pubitemid 38510200)
    • (2004) Lancet Neurology , vol.3 , Issue.5 , pp. 291-304
    • Schols, L.1    Bauer, P.2    Schmidt, T.3    Schulte, T.4    Riess, O.5
  • 4
    • 33749504441 scopus 로고    scopus 로고
    • Evaluation of treatment effects in Alzheimer's and other neurodegenerative diseases by MRI and MRS
    • DOI 10.1002/nbm.1062
    • Mueller SG, Schuff N, Weiner MW. Evaluation of treatment effects in Alzheimer's and other neurodegenerative diseases by MRI and MRS. NMR Biomed. 2006;19(6):655-68. (Pubitemid 44515610)
    • (2006) NMR in Biomedicine , vol.19 , Issue.6 , pp. 655-668
    • Mueller, S.G.1    Schuff, N.2    Weiner, M.W.3
  • 5
    • 65549134765 scopus 로고    scopus 로고
    • Pathogenic mechanisms of a polyglutaminemediated neurodegenerative disease, spinocerebellar ataxia type 1
    • Zoghbi HY, Orr HT. Pathogenic mechanisms of a polyglutaminemediated neurodegenerative disease, spinocerebellar ataxia type 1. J Biol Chem. 2009;284(12):7425-9.
    • (2009) J Biol Chem. , vol.284 , Issue.12 , pp. 7425-7429
    • Zoghbi, H.Y.1    Orr, H.T.2
  • 6
    • 25844506224 scopus 로고    scopus 로고
    • Therapeutics development for triplet repeat expansion diseases
    • DOI 10.1038/nrg1690
    • Di Prospero NA, Fischbeck KH. Therapeutics development for triplet repeat expansion diseases. Nat Rev Genet. 2005;6(10):756-65. (Pubitemid 41400833)
    • (2005) Nature Reviews Genetics , vol.6 , Issue.10 , pp. 756-765
    • Di Prospero, N.A.1    Fischbeck, K.H.2
  • 7
    • 67651177579 scopus 로고    scopus 로고
    • Patterns of fractional anisotropy changes in white matter of cerebellar peduncles distinguish spinocerebellar ataxia-1 from multiple system atrophy and other ataxia syndromes
    • Prakash N, Hageman N, Hua X, Toga AW, Perlman SL, Salamon N. Patterns of fractional anisotropy changes in white matter of cerebellar peduncles distinguish spinocerebellar ataxia-1 from multiple system atrophy and other ataxia syndromes. Neuroimage. 2009;47 Suppl 2:T72-81.
    • (2009) Neuroimage. , vol.47 , Issue.SUPPL. 2
    • Prakash, N.1    Hageman, N.2    Hua, X.3    Toga, A.W.4    Perlman, S.L.5    Salamon, N.6
  • 10
    • 0031683168 scopus 로고    scopus 로고
    • Autosomal dominant cerebellar ataxia type I. MRI-based volumetry of posterior fossa structures and basal ganglia in spinocerebellar ataxia types 1, 2 and 3
    • DOI 10.1093/brain/121.9.1687
    • Klockgether T, Skalej M,Wedekind D, Luft AR,Welte D, Schulz JB, et al. Autosomal dominant cerebellar ataxia type I. MRI-based volumetry of posterior fossa structures and basal ganglia in spinocerebellar ataxia types 1, 2 and 3. Brain. 1998;121(Pt 9):1687-93. (Pubitemid 28419974)
    • (1998) Brain , vol.121 , Issue.9 , pp. 1687-1693
    • Klockgether, T.1    Skalej, M.2    Wedekind, D.3    Luft, A.R.4    Welte, D.5    Schulz, J.B.6    Abele, M.7    Burk, K.8    Laccone, F.9    Brice, A.10    Dichgans, J.11
  • 13
    • 70349962976 scopus 로고    scopus 로고
    • Visualization, quantification and correlation of brain atrophy with clinical symptoms in spinocerebellar ataxia types 1, 3 and 6
    • Schulz JB, Borkert J, Wolf S, Schmitz-Hübsch T, Rakowicz M, Mariotti C, et al. Visualization, quantification and correlation of brain atrophy with clinical symptoms in spinocerebellar ataxia types 1, 3 and 6. Neuroimage. 2010;49(1):158-68.
    • (2010) Neuroimage , vol.49 , Issue.1 , pp. 158-168
    • Schulz, J.B.1    Borkert, J.2    Wolf, S.3    Schmitz-Hübsch, T.4    Rakowicz, M.5    Mariotti, C.6
  • 14
    • 33749515747 scopus 로고    scopus 로고
    • Dissociation of grey and white matter reduction in spinocerebellar ataxia type 3 and 6: A voxel-based morphometry study
    • DOI 10.1016/j.neulet.2006.09.007, PII S030439400600927X
    • Lukas C, Schöls L, Bellenberg B, Rub U, Przuntek H, Schmid G, et al. Dissociation of grey and white matter reduction in spinocerebellar ataxia type 3 and 6: a voxel-based morphometry study. Neurosci Lett. 2006;408(3):230-5. (Pubitemid 44528871)
    • (2006) Neuroscience Letters , vol.408 , Issue.3 , pp. 230-235
    • Lukas, C.1    Schols, L.2    Bellenberg, B.3    Rub, U.4    Przuntek, H.5    Schmid, G.6    Koster, O.7    Suchan, B.8
  • 15
    • 52049124455 scopus 로고    scopus 로고
    • Brain white matter damage in SCA1 and SCA2. An in vivo study using voxel-based morphometry, histogram analysis of mean diffusivity and tract-based spatial statistics
    • Della Nave R, Ginestroni A, Tessa C, Salvatore E, De Grandis D, Plasmati R, et al. Brain white matter damage in SCA1 and SCA2. An in vivo study using voxel-based morphometry, histogram analysis of mean diffusivity and tract-based spatial statistics. Neuroimage. 2008;43(1):10-9.
    • (2008) Neuroimage. , vol.43 , Issue.1 , pp. 10-19
    • Della Nave, R.1    Ginestroni, A.2    Tessa, C.3    Salvatore, E.4    De Grandis, D.5    Plasmati, R.6
  • 17
    • 3242708709 scopus 로고    scopus 로고
    • Characterization of ataxias with magnetic resonance imaging and spectroscopy
    • DOI 10.1016/j.parkreldis.2004.02.006, PII S135380200400032X
    • Viau M, Boulanger Y. Characterization of ataxias with magnetic resonance imaging and spectroscopy. Parkinsonism Relat Disord. 2004;10(6):335-51. (Pubitemid 38942789)
    • (2004) Parkinsonism and Related Disorders , vol.10 , Issue.6 , pp. 335-351
    • Viau, M.1    Boulanger, Y.2
  • 19
    • 0033226834 scopus 로고    scopus 로고
    • 1H NMR Spectra of the Rat Brain
    • Pfeuffer J, Tkáč I, Provencher SW, Gruetter R. Toward an in vivo neurochemical profile: quantification of 18 metabolites in shortecho-time 1H NMR spectra of the rat brain. J Magn Reson. 1999;141(1):104-20. (Pubitemid 129608901)
    • (1999) Journal of Magnetic Resonance , vol.141 , Issue.1 , pp. 104-120
    • Pfeuffer, J.1    Tkac, I.2    Provencher, S.W.3    Gruetter, R.4
  • 20
    • 70349613203 scopus 로고    scopus 로고
    • In vivo 1H NMR spectroscopy of the human brain at high magnetic fields: Metabolite quantification at 4T vs. 7T
    • Tkáč I, Öz G, Adriany G, Ugurbil K, Gruetter R. In vivo 1H NMR spectroscopy of the human brain at high magnetic fields: Metabolite quantification at 4T vs. 7T. Magn Reson Med.2009;62(4):868-79.
    • (2009) Magn Reson Med. , vol.62 , Issue.4 , pp. 868-879
    • Tkáč, I.1    Öz, G.2    Adriany, G.3    Ugurbil, K.4    Gruetter, R.5
  • 21
    • 77955064254 scopus 로고    scopus 로고
    • Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status
    • Öz G, Hutter D, Tkáč I, Clark HB, Gross MD, Jiang H, et al. Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status. Mov Disord. 2010;25 (9):1253-61.
    • (2010) Mov Disord. , vol.25 , Issue.9 , pp. 1253-1261
    • Öz, G.1    Hutter, D.2    Tkáč, I.3    Clark, H.B.4    Gross, M.D.5    Jiang, H.6
  • 22
    • 77949371220 scopus 로고    scopus 로고
    • Noninvasive detection of presymptomatic and progressive neurodegeneration in a mouse model of spinocerebellar ataxia type 1
    • Öz G, Nelson CD, Koski DM, Henry PG, Marjańska M, Deelchand DK, et al. Noninvasive detection of presymptomatic and progressive neurodegeneration in a mouse model of spinocerebellar ataxia type 1. J Neurosci. 2010;30(10):3831-8.
    • (2010) J Neurosci. , vol.30 , Issue.10 , pp. 3831-3838
    • Öz, G.1    Nelson, C.D.2    Koski, D.M.3    Henry, P.G.4    Marjańska, M.5    Deelchand, D.K.6
  • 24
    • 33847709488 scopus 로고    scopus 로고
    • Spontaneous and induced mouse mutations with cerebellar dysfunctions: Behavior and neurochemistry
    • DOI 10.1016/j.brainres.2006.01.031, PII S0006899306001004, A Catalog of the Neurological Mutants of the Mouse Revisited
    • Lalonde R, Strazielle C. Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry. Brain Res. 2007;1140:51-74. (Pubitemid 46371293)
    • (2007) Brain Research , vol.1140 , Issue.1 , pp. 51-74
    • Lalonde, R.1    Strazielle, C.2
  • 26
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • DOI 10.1002/mrm.1910300604
    • Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med. 1993;30 (6):672-9. (Pubitemid 23360802)
    • (1993) Magnetic Resonance in Medicine , vol.30 , Issue.6 , pp. 672-679
    • Provencher, S.W.1
  • 29
    • 0031731910 scopus 로고    scopus 로고
    • N-acetyl aspartate: A marker for neuronal loss or mitochondrial dysfunction
    • Clark JB. N-acetyl aspartate: a marker for neuronal loss or mitochondrial dysfunction. Dev Neurosci. 1998;20(4-5):271-6.
    • (1998) Dev Neurosci. , vol.20 , Issue.4-5 , pp. 271-276
    • Clark, J.B.1
  • 30
    • 0027749707 scopus 로고
    • Multinuclear NMR studies on the energy metabolism of glial and neuronal cells
    • Brand A, Richter-Landsberg C, Leibfritz D. Multinuclear NMR studies on the energy metabolism of glial and neuronal cells. Dev Neurosci. 1993;15(3-5):289-98. (Pubitemid 24258162)
    • (1993) Developmental Neuroscience , vol.15 , Issue.3-5 , pp. 289-298
    • Brand, A.1    Richter-Landsberg, C.2    Leibfritz, D.3
  • 32
    • 23044458468 scopus 로고    scopus 로고
    • 1H magnetic resonance spectroscopy of autosomal ataxias
    • DOI 10.1016/j.brainres.2005.05.015, PII S0006899305007304
    • 1H magnetic resonance spectroscopy of autosomal ataxias. Brain Res. 2005;1049(2):191-202. (Pubitemid 41072935)
    • (2005) Brain Research , vol.1049 , Issue.2 , pp. 191-202
    • Viau, M.1    Marchand, L.2    Bard, C.3    Boulanger, Y.4
  • 34
    • 0036979072 scopus 로고    scopus 로고
    • A comprehensive review of proton magnetic resonance spectroscopy studies in dementia and Parkinson's disease
    • DOI 10.1159/000064927
    • Firbank MJ, Harrison RM, O'Brien JT. A comprehensive review of proton magnetic resonance spectroscopy studies in dementia and Parkinson's disease. Dement Geriatr Cogn Disord. 2002;14(2):64-76. (Pubitemid 36152947)
    • (2002) Dementia and Geriatric Cognitive Disorders , vol.14 , Issue.2 , pp. 64-76
    • Firbank, M.J.1    Harrison, R.M.2    O'Brien, J.T.3
  • 35
    • 17844392364 scopus 로고    scopus 로고
    • The pathogenesis of spinocerebellar ataxia
    • DOI 10.1080/14734220510007950
    • Koeppen AH. The pathogenesis of spinocerebellar ataxia. Cerebellum. 2005;4(1):62-73. (Pubitemid 40592813)
    • (2005) Cerebellum , vol.4 , Issue.1 , pp. 62-73
    • Koeppen, A.H.1
  • 36
    • 0030847065 scopus 로고    scopus 로고
    • The neuropathology of CAG repeat diseases: Review and update of genetic and molecular features
    • Robitaille Y, Lopes-Cendes I, Becher M, Rouleau G, Clark AW. The neuropathology of CAG repeat diseases: review and update of genetic and molecular features. Brain Pathol. 1997;7(3):901-26. (Pubitemid 27346734)
    • (1997) Brain Pathology , vol.7 , Issue.3 , pp. 901-926
    • Robitaille, Y.1    Lopes-Cendes, I.2    Becher, M.3    Rouleau, G.4    Clark, A.W.5
  • 37
    • 0033111229 scopus 로고    scopus 로고
    • Autosomal dominant spinocerebellar degenerations. Clinical, pathological, and genetic correlations
    • Iwabuchi K, Tsuchiya K, Uchihara T, Yagishita S. Autosomal dominant spinocerebellar degenerations. Clinical, pathological, and genetic correlations. Rev Neurol (Paris). 1999;155(4):255-70.
    • (1999) Rev Neurol (Paris). , vol.155 , Issue.4 , pp. 255-270
    • Iwabuchi, K.1    Tsuchiya, K.2    Uchihara, T.3    Yagishita, S.4
  • 40
    • 10344260246 scopus 로고    scopus 로고
    • The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: Clinicopathological correlations
    • DOI 10.1093/brain/awh303
    • Ozawa T, Paviour D, Quinn NP, Josephs KA, Sangha H, Kilford L, et al. The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. Brain. 2004;127(Pt 12):2657-71. (Pubitemid 39627375)
    • (2004) Brain , vol.127 , Issue.12 , pp. 2657-2671
    • Ozawa, T.1    Paviour, D.2    Quinn, N.P.3    Josephs, K.A.4    Sangha, H.5    Kilford, L.6    Healy, D.G.7    Wood, N.W.8    Lees, A.J.9    Holton, J.L.10    Revesz, T.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.