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Volumn 140, Issue 1-2, 2011, Pages 1-6

Role of the gut as a primary lymphoid organ

Author keywords

CD8 intraepithelial T lymphocyte; Gut; Precursor export; T cell differentiation

Indexed keywords

CD8ALPHA ANTIGEN; LEUKEMIA ANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; TETRAMER;

EID: 80051790016     PISSN: 01652478     EISSN: 18790542     Source Type: Journal    
DOI: 10.1016/j.imlet.2011.05.009     Document Type: Review
Times cited : (18)

References (52)
  • 1
    • 0025974008 scopus 로고
    • The Vβ repertoire of mouse gut homodimeric α CD8+ intraepithelial T cell receptor α/β+ lymphocytes reveals a major extrathymic pathway of T cell differentiation
    • Rocha B., Vassalli P., Guy-Grand D. The Vβ repertoire of mouse gut homodimeric α CD8+ intraepithelial T cell receptor α/β+ lymphocytes reveals a major extrathymic pathway of T cell differentiation. J Exp Med 1991, 173:483-486.
    • (1991) J Exp Med , vol.173 , pp. 483-486
    • Rocha, B.1    Vassalli, P.2    Guy-Grand, D.3
  • 2
    • 0034802332 scopus 로고    scopus 로고
    • In situ demonstration of intraepithelial lymphocyte adhesion to villus microvessels of the small intestine
    • Koseki S., Miura S., Fujimori H., Hokari R., Komoto S., Hara Y., et al. In situ demonstration of intraepithelial lymphocyte adhesion to villus microvessels of the small intestine. Int Immunol 2001, 13:1165-1174.
    • (2001) Int Immunol , vol.13 , pp. 1165-1174
    • Koseki, S.1    Miura, S.2    Fujimori, H.3    Hokari, R.4    Komoto, S.5    Hara, Y.6
  • 3
    • 0036802422 scopus 로고    scopus 로고
    • CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa
    • Svensson M., Marsal J., Ericsson A., Carramolino L., Broden T., Marquez G., et al. CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa. J Clin Invest 2002, 110:1113-1121.
    • (2002) J Clin Invest , vol.110 , pp. 1113-1121
    • Svensson, M.1    Marsal, J.2    Ericsson, A.3    Carramolino, L.4    Broden, T.5    Marquez, G.6
  • 4
    • 0036533388 scopus 로고    scopus 로고
    • Gut intraepithelial lymphocyte development
    • Guy-Grand D., Vassalli P. Gut intraepithelial lymphocyte development. Curr Opin Immunol 2002, 14:255-259.
    • (2002) Curr Opin Immunol , vol.14 , pp. 255-259
    • Guy-Grand, D.1    Vassalli, P.2
  • 7
    • 0026034717 scopus 로고
    • Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation
    • Guy-Grand D., Cerf-Bensussan N., Malissen B., Malassis-Seris M., Briottet C., Vassalli P. Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J Exp Med 1991, 173:471-481.
    • (1991) J Exp Med , vol.173 , pp. 471-481
    • Guy-Grand, D.1    Cerf-Bensussan, N.2    Malissen, B.3    Malassis-Seris, M.4    Briottet, C.5    Vassalli, P.6
  • 8
    • 0025936929 scopus 로고
    • Phenotypic complexity of intraepithelial lymphocytes of the small intestine
    • Lefrancois L. Phenotypic complexity of intraepithelial lymphocytes of the small intestine. J Immunol 1991, 147:1746-1751.
    • (1991) J Immunol , vol.147 , pp. 1746-1751
    • Lefrancois, L.1
  • 9
    • 0027309199 scopus 로고
    • Expression of the CD28 costimulatory molecule on subsets of murine intestinal intraepithelial lymphocytes correlates with lineage and responsiveness
    • Ohteki T., MacDonald H.R. Expression of the CD28 costimulatory molecule on subsets of murine intestinal intraepithelial lymphocytes correlates with lineage and responsiveness. Eur J Immunol 1993, 23:1251-1255.
    • (1993) Eur J Immunol , vol.23 , pp. 1251-1255
    • Ohteki, T.1    MacDonald, H.R.2
  • 11
    • 0028998222 scopus 로고
    • Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo
    • Huleatt J.W., Lefrancois L. Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo. J Immunol 1995, 154:5684-5693.
    • (1995) J Immunol , vol.154 , pp. 5684-5693
    • Huleatt, J.W.1    Lefrancois, L.2
  • 12
    • 0029848909 scopus 로고    scopus 로고
    • Complexity of the mouse gut T cell immune system: identification of two distinct natural killer T cell intraepithelial lineages
    • Guy-Grand D., Cuenod-Jabri B., Malassis-Seris M., Selz F., Vassalli P. Complexity of the mouse gut T cell immune system: identification of two distinct natural killer T cell intraepithelial lineages. Eur J Immunol 1996, 26:2248-2256.
    • (1996) Eur J Immunol , vol.26 , pp. 2248-2256
    • Guy-Grand, D.1    Cuenod-Jabri, B.2    Malassis-Seris, M.3    Selz, F.4    Vassalli, P.5
  • 13
    • 0028170171 scopus 로고
    • Oligoclonal repertoire of the CD8αα and the CD8αβ TCR-α/β murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells
    • Regnault A., Cumano A., Vassalli P., Guy-Grand D., Kourilsky P. Oligoclonal repertoire of the CD8αα and the CD8αβ TCR-α/β murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells. J Exp Med 1994, 180:1345-1358.
    • (1994) J Exp Med , vol.180 , pp. 1345-1358
    • Regnault, A.1    Cumano, A.2    Vassalli, P.3    Guy-Grand, D.4    Kourilsky, P.5
  • 14
    • 0029872570 scopus 로고    scopus 로고
    • The expansion and selection of T cell receptor αβ intestinal intraepithelial T cell clones
    • Regnault A., Levraud J.P., Lim A., Six A., Moreau C., Cumano A., et al. The expansion and selection of T cell receptor αβ intestinal intraepithelial T cell clones. Eur J Immunol 1996, 26:914-921.
    • (1996) Eur J Immunol , vol.26 , pp. 914-921
    • Regnault, A.1    Levraud, J.P.2    Lim, A.3    Six, A.4    Moreau, C.5    Cumano, A.6
  • 15
    • 0031202922 scopus 로고    scopus 로고
    • Distinct methylation states of the CD8β gene in peripheral T cells and intraepithelial lymphocytes
    • Hamerman J.A., Page S.T., Pullen A.M. Distinct methylation states of the CD8β gene in peripheral T cells and intraepithelial lymphocytes. J Immunol 1997, 159:1240-1246.
    • (1997) J Immunol , vol.159 , pp. 1240-1246
    • Hamerman, J.A.1    Page, S.T.2    Pullen, A.M.3
  • 16
    • 0028356473 scopus 로고
    • Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation
    • Guy-Grand D., Rocha B., Mintz P., Malassis-Seris M., Selz F., Malissen B., et al. Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation. J Exp Med 1994, 180:673-679.
    • (1994) J Exp Med , vol.180 , pp. 673-679
    • Guy-Grand, D.1    Rocha, B.2    Mintz, P.3    Malassis-Seris, M.4    Selz, F.5    Malissen, B.6
  • 18
    • 0026694668 scopus 로고
    • Selection of intraepithelial lymphocytes with CD8αα co-receptors by self-antigen in the murine gut
    • Rocha B., von Boehmer H., Guy-Grand D. Selection of intraepithelial lymphocytes with CD8αα co-receptors by self-antigen in the murine gut. Proc Natl Acad Sci USA 1992, 89:5336-5340.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5336-5340
    • Rocha, B.1    von Boehmer, H.2    Guy-Grand, D.3
  • 20
    • 0034831284 scopus 로고    scopus 로고
    • Enhanced formation of azoxymethane-induced colorectal adenocarcinoma in γδ T lymphocyte-deficient mice
    • Matsuda S., Kudoh S., Katayama S. Enhanced formation of azoxymethane-induced colorectal adenocarcinoma in γδ T lymphocyte-deficient mice. Jpn J Cancer Res 2001, 92:880-885.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 880-885
    • Matsuda, S.1    Kudoh, S.2    Katayama, S.3
  • 21
  • 22
    • 0037013968 scopus 로고    scopus 로고
    • A unique subset of self-specific intra-intestinal T cells maintains gut integrity
    • Poussier P., Ning T., Banerjee D., Julius M. A unique subset of self-specific intra-intestinal T cells maintains gut integrity. J Exp Med 2002, 195:1491-1497.
    • (2002) J Exp Med , vol.195 , pp. 1491-1497
    • Poussier, P.1    Ning, T.2    Banerjee, D.3    Julius, M.4
  • 23
    • 33646874429 scopus 로고    scopus 로고
    • TCRγδ intraepithelial lymphocytes are required for self-tolerance
    • Locke N.R., Stankovic S., Funda D.P., Harrison L.C. TCRγδ intraepithelial lymphocytes are required for self-tolerance. J Immunol 2006, 176:6553-6559.
    • (2006) J Immunol , vol.176 , pp. 6553-6559
    • Locke, N.R.1    Stankovic, S.2    Funda, D.P.3    Harrison, L.C.4
  • 24
    • 0032513388 scopus 로고    scopus 로고
    • Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells
    • Groh V., Steinle A., Bauer S., Spies T. Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells. Science 1998, 279:1737-1740.
    • (1998) Science , vol.279 , pp. 1737-1740
    • Groh, V.1    Steinle, A.2    Bauer, S.3    Spies, T.4
  • 25
    • 0035162229 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes: exploring the third way in immunology
    • Hayday A., Theodoridis E., Ramsburg E., Shires J. Intraepithelial lymphocytes: exploring the third way in immunology. Nat Immunol 2001, 2:997-1003.
    • (2001) Nat Immunol , vol.2 , pp. 997-1003
    • Hayday, A.1    Theodoridis, E.2    Ramsburg, E.3    Shires, J.4
  • 26
    • 0029000949 scopus 로고
    • Intra- and extra-thymic expression of the pre-T cell receptor α gene
    • Bruno L., Rocha B., Rolink A., von Boehmer H., Rodewald H.R. Intra- and extra-thymic expression of the pre-T cell receptor α gene. Eur J Immunol 1995, 25:1877-1882.
    • (1995) Eur J Immunol , vol.25 , pp. 1877-1882
    • Bruno, L.1    Rocha, B.2    Rolink, A.3    von Boehmer, H.4    Rodewald, H.R.5
  • 28
    • 0343183279 scopus 로고    scopus 로고
    • Enterocyte expression of interleukin 7 induces development of γδ T cells and Peyer's patches
    • Laky K., Lefrancois L., Lingenheld E.G., Ishikawa H., Lewis J.M., Olson S., et al. Enterocyte expression of interleukin 7 induces development of γδ T cells and Peyer's patches. J Exp Med 2000, 191:1569-1580.
    • (2000) J Exp Med , vol.191 , pp. 1569-1580
    • Laky, K.1    Lefrancois, L.2    Lingenheld, E.G.3    Ishikawa, H.4    Lewis, J.M.5    Olson, S.6
  • 29
    • 0141920522 scopus 로고    scopus 로고
    • Extrathymic TCR gene rearrangement in human small intestine: identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression
    • Bas A., Hammarstrom S.G., Hammarstrom M.L. Extrathymic TCR gene rearrangement in human small intestine: identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression. J Immunol 2003, 171:3359-3371.
    • (2003) J Immunol , vol.171 , pp. 3359-3371
    • Bas, A.1    Hammarstrom, S.G.2    Hammarstrom, M.L.3
  • 30
    • 75149150749 scopus 로고    scopus 로고
    • Opening the crypt: current facts and hypotheses on the function of cryptopatches
    • Eberl G., Sawa S. Opening the crypt: current facts and hypotheses on the function of cryptopatches. Trends Immunol 2010, 31:50-55.
    • (2010) Trends Immunol , vol.31 , pp. 50-55
    • Eberl, G.1    Sawa, S.2
  • 31
    • 0033636261 scopus 로고    scopus 로고
    • Gut cryptopatches: direct evidence of extrathymic anatomical sites for intestinal T lymphopoiesis
    • Suzuki K., Oida T., Hamada H., Hitotsumatsu O., Watanabe M., Hibi T., et al. Gut cryptopatches: direct evidence of extrathymic anatomical sites for intestinal T lymphopoiesis. Immunity 2000, 13:691-702.
    • (2000) Immunity , vol.13 , pp. 691-702
    • Suzuki, K.1    Oida, T.2    Hamada, H.3    Hitotsumatsu, O.4    Watanabe, M.5    Hibi, T.6
  • 32
    • 0029854809 scopus 로고    scopus 로고
    • Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop
    • Kanamori Y., Ishimaru K., Nanno M., Maki K., Ikuta K., Nariuchi H., et al. Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop. J Exp Med 1996, 184:1449-1459.
    • (1996) J Exp Med , vol.184 , pp. 1449-1459
    • Kanamori, Y.1    Ishimaru, K.2    Nanno, M.3    Maki, K.4    Ikuta, K.5    Nariuchi, H.6
  • 33
    • 33846781580 scopus 로고    scopus 로고
    • The extrathymic T-cell differentiation in the murine gut
    • Rocha B. The extrathymic T-cell differentiation in the murine gut. Immunol Rev 2007, 215:166-177.
    • (2007) Immunol Rev , vol.215 , pp. 166-177
    • Rocha, B.1
  • 34
    • 0027153201 scopus 로고
    • A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • Godfrey D.I., Kennedy J., Suda T., Zlotnik A. A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J Immunol 1993, 150:4244-4252.
    • (1993) J Immunol , vol.150 , pp. 4244-4252
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 36
    • 0035697584 scopus 로고    scopus 로고
    • Molecular characterization of gut T cell precursors in euthymic and athymic mice
    • Lambolez F., Rocha B. Molecular characterization of gut T cell precursors in euthymic and athymic mice. Adv Exp Med Biol 2001, 495:15-24.
    • (2001) Adv Exp Med Biol , vol.495 , pp. 15-24
    • Lambolez, F.1    Rocha, B.2
  • 37
    • 42149122707 scopus 로고    scopus 로고
    • RORγt is dispensable for the development of intestinal mucosal T cells
    • Naito T., Shiohara T., Hibi T., Suematsu M., Ishikawa H. RORγt is dispensable for the development of intestinal mucosal T cells. Mucosal Immunol 2008, 1:198-207.
    • (2008) Mucosal Immunol , vol.1 , pp. 198-207
    • Naito, T.1    Shiohara, T.2    Hibi, T.3    Suematsu, M.4    Ishikawa, H.5
  • 38
    • 0027219936 scopus 로고
    • Thymus influences the development of extrathymically derived intestinal intraepithelial lymphocytes
    • Lin T., Matsuzaki G., Kenai H., Nakamura T., Nomoto K. Thymus influences the development of extrathymically derived intestinal intraepithelial lymphocytes. Eur J Immunol 1993, 23:1968-1974.
    • (1993) Eur J Immunol , vol.23 , pp. 1968-1974
    • Lin, T.1    Matsuzaki, G.2    Kenai, H.3    Nakamura, T.4    Nomoto, K.5
  • 39
    • 0028178236 scopus 로고
    • CD3-CD8+ intestinal intraepithelial lymphocytes (IEL) and the extrathymic development of IEL
    • Lin T., Matsuzaki G., Yoshida H., Kobayashi N., Kenai H., Omoto K., et al. CD3-CD8+ intestinal intraepithelial lymphocytes (IEL) and the extrathymic development of IEL. Eur J Immunol 1994, 24:1080-1087.
    • (1994) Eur J Immunol , vol.24 , pp. 1080-1087
    • Lin, T.1    Matsuzaki, G.2    Yoshida, H.3    Kobayashi, N.4    Kenai, H.5    Omoto, K.6
  • 40
    • 29244468256 scopus 로고    scopus 로고
    • The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs
    • Lambolez F., Arcangeli M.L., Joret A.M., Pasqualetto V., Cordier C., Di Santo J.P., et al. The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs. Nat Immunol 2006, 7:76-82.
    • (2006) Nat Immunol , vol.7 , pp. 76-82
    • Lambolez, F.1    Arcangeli, M.L.2    Joret, A.M.3    Pasqualetto, V.4    Cordier, C.5    Di Santo, J.P.6
  • 42
    • 78650843523 scopus 로고    scopus 로고
    • The role of the gut as a primary lymphoid organ: CD8αα intraepithelial T lymphocytes in euthymic mice derive from very immature CD44+ thymocyte precursors
    • Peaudecerf L., Ribeiro Dos Santos P., Boudil A., Ezine S., Pardigon N., Rocha B. The role of the gut as a primary lymphoid organ: CD8αα intraepithelial T lymphocytes in euthymic mice derive from very immature CD44+ thymocyte precursors. Mucosal Immunol 2010, 4:93-101.
    • (2010) Mucosal Immunol , vol.4 , pp. 93-101
    • Peaudecerf, L.1    Ribeiro Dos Santos, P.2    Boudil, A.3    Ezine, S.4    Pardigon, N.5    Rocha, B.6
  • 43
    • 34247882592 scopus 로고    scopus 로고
    • Zoned out: functional mapping of stromal signaling microenvironments in the thymus
    • Petrie H.T., Zuniga-Pflucker J.C. Zoned out: functional mapping of stromal signaling microenvironments in the thymus. Annu Rev Immunol 2007, 25:649-679.
    • (2007) Annu Rev Immunol , vol.25 , pp. 649-679
    • Petrie, H.T.1    Zuniga-Pflucker, J.C.2
  • 44
    • 33745014890 scopus 로고    scopus 로고
    • Stage-specific and differential notch dependency at the αβ and γδ T lineage bifurcation
    • Ciofani M., Knowles G.C., Wiest D.L., von Boehmer H., Zuniga-Pflucker J.C. Stage-specific and differential notch dependency at the αβ and γδ T lineage bifurcation. Immunity 2006, 25:105-116.
    • (2006) Immunity , vol.25 , pp. 105-116
    • Ciofani, M.1    Knowles, G.C.2    Wiest, D.L.3    von Boehmer, H.4    Zuniga-Pflucker, J.C.5
  • 45
    • 0033104727 scopus 로고    scopus 로고
    • Characterization of TCR gene rearrangements during adult murine T cell development
    • Livak F., Tourigny M., Schatz D.G., Petrie H.T. Characterization of TCR gene rearrangements during adult murine T cell development. J Immunol 1999, 162:2575-2580.
    • (1999) J Immunol , vol.162 , pp. 2575-2580
    • Livak, F.1    Tourigny, M.2    Schatz, D.G.3    Petrie, H.T.4
  • 46
    • 0032514764 scopus 로고    scopus 로고
    • Kinetics of T cell receptor β γ, and δ rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44+CD25+ Pro-T thymocytes
    • Capone M., Hockett R.D., Zlotnik A. Kinetics of T cell receptor β γ, and δ rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44+CD25+ Pro-T thymocytes. Proc Natl Acad Sci USA 1998, 95:12522-12527.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12522-12527
    • Capone, M.1    Hockett, R.D.2    Zlotnik, A.3
  • 47
    • 57849145994 scopus 로고    scopus 로고
    • Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin
    • Luci C., Reynders A., Ivanov I.I., Cognet C., Chiche L., Chasson L., et al. Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin. Nat Immunol 2009, 10:75-82.
    • (2009) Nat Immunol , vol.10 , pp. 75-82
    • Luci, C.1    Reynders, A.2    Ivanov, I.I.3    Cognet, C.4    Chiche, L.5    Chasson, L.6
  • 48
    • 3042720708 scopus 로고    scopus 로고
    • Thymic origin of intestinal αβ T cells revealed by fate14 mapping of RORγt+ cells
    • Eberl G., Littman D.R. Thymic origin of intestinal αβ T cells revealed by fate14 mapping of RORγt+ cells. Science (New York, NY) 2004, 305:248-251.
    • (2004) Science (New York, NY) , vol.305 , pp. 248-251
    • Eberl, G.1    Littman, D.R.2
  • 49
    • 43549096114 scopus 로고    scopus 로고
    • Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping
    • Egawa T., Kreslavsky T., Littman D.R., von Boehmer H. Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping. PLoS One 2008, 3:e1512.
    • (2008) PLoS One , vol.3
    • Egawa, T.1    Kreslavsky, T.2    Littman, D.R.3    von Boehmer, H.4
  • 50
    • 0032585722 scopus 로고    scopus 로고
    • RORγT, a thymus-specific isoform of the orphan nuclear receptor RORγ/TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoter
    • Villey I., de Chasseval R., de Villartay J.P. RORγT, a thymus-specific isoform of the orphan nuclear receptor RORγ/TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoter. Eur J Immunol 1999, 29:4072-4080.
    • (1999) Eur J Immunol , vol.29 , pp. 4072-4080
    • Villey, I.1    de Chasseval, R.2    de Villartay, J.P.3
  • 51
    • 33749526537 scopus 로고    scopus 로고
    • Identification of pre- and postselection TCRαβ+ intraepithelial lymphocyte precursors in the thymus
    • Gangadharan D., Lambolez F., Attinger A., Wang-Zhu Y., Sullivan B.A., Cheroutre H. Identification of pre- and postselection TCRαβ+ intraepithelial lymphocyte precursors in the thymus. Immunity 2006, 25:631-641.
    • (2006) Immunity , vol.25 , pp. 631-641
    • Gangadharan, D.1    Lambolez, F.2    Attinger, A.3    Wang-Zhu, Y.4    Sullivan, B.A.5    Cheroutre, H.6
  • 52
    • 22344450566 scopus 로고    scopus 로고
    • The timing of TCR α expression critically influences T cell development and selection
    • Baldwin T.A., Sandau M.M., Jameson S.C., Hogquist K.A. The timing of TCR α expression critically influences T cell development and selection. J Exp Med 2005, 202:111-121.
    • (2005) J Exp Med , vol.202 , pp. 111-121
    • Baldwin, T.A.1    Sandau, M.M.2    Jameson, S.C.3    Hogquist, K.A.4


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