Spinocerebellar ataxia type 2 (SCA2): Identification of early brain degeneration in one monozygous twin in the initial disease stage

Cerebellum

Volumn 10, Issue 2, 2011, Pages 245-253

  Hoche, Franziska ^a   Balikó, Laszlo ^b   Den Dunnen, Wilfred ^c   Steinecker, Katalin ^b   Bartos, Laszlo ^b   Sáfrány, Eniko ^d   Auburger, Georg ^a   Deller, Thomas ^a   Korf, Horst Werner ^a   Klockgether, Thomas ^e   Rüb, Udo ^a   Melegh, Bela ^d  

^a GOETHE UNIVERSITY   (Germany)

^b Hungary   (Hungary)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d UNIVERSITY OF PÉCS   (Hungary)

^e UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

ADCA; Ataxia; Polyglutamine; SCA2; Spinocerebellar ataxia

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BRAIN DEGENERATION; CAG REPEAT; CELL LOSS; CEREBELLUM NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; FACIAL NERVE NUCLEUS; FEMALE; GRAY MATTER; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFERIOR OLIVE; INTERPOSITUS NUCLEUS; LATERAL VESTIBULAR NUCLEUS; MALE; MONOZYGOTIC TWINS; NEUROLOGIC EXAMINATION; NEUROPATHOLOGY; OCULOMOTOR NUCLEUS; ONSET AGE; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; PURKINJE CELL; PYRAMIDAL NERVE CELL; RAPHE NUCLEUS; SPINOCEREBELLAR ATAXIA TYPE 2; SPINOCEREBELLAR DEGENERATION; SUBSTANTIA NIGRA; THALAMUS NUCLEUS; TISSUE STRUCTURE;

ADENOCARCINOMA; ADOLESCENT; ADULT; AGE OF ONSET; AGED; BRAIN; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE DEGENERATION; NERVE TISSUE PROTEINS; PEDIGREE; POLYMERASE CHAIN REACTION; PROSTATIC NEOPLASMS; SPINOCEREBELLAR ATAXIAS; TRINUCLEOTIDE REPEAT EXPANSION; TWINS, MONOZYGOTIC;

EID: 80051779924     PISSN: 14734222     EISSN: 14734230     Source Type: Journal    
DOI: 10.1007/s12311-010-0239-9     Document Type: Article

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