Intestinal steroid profiles and microbiota composition in colitic mice

Gut Microbes

Volumn 2, Issue 3, 2011, Pages 159-166

  Wohlgemuth, Steffen ^a,b   Keller, Sylvia ^c   Kertscher, Romy ^c   Stadion, Mandy ^a   Haller, Dirk ^d   Kisling, Sigrid ^d   Jahreis, Gerhard ^c   Blaut, Michael ^a   Loh, Gunnar ^a,b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b Junior Research Group Microbiota Host Interactions   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Bile acids; Cholesterol; Colorectal cancer; Coprostanol; Inflammatory bowel disease; Intestinal microbiota; Neutral sterols

Indexed keywords

BILE ACID; CHOLESTEROL; CHOLIC ACID; INTERLEUKIN 10; STEROID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CECUM; CLOSTRIDIUM; COLON; COLORECTAL TUMOR; CONTROLLED STUDY; ENTERITIS; ENTEROCOCCUS GALLINARUM; ESCHERICHIA COLI; INTESTINE FLORA; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; MOUSE; NONHUMAN; ROBINSONIELLA PEORIENSIS;

ANIMALS; BACTERIA; COLITIS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-10; INTESTINES; MALE; METAGENOME; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; STEROIDS;

ANIMALIA; BACTERIA (MICROORGANISMS); CLOSTRIDIUM INNOCUUM; ENTEROCOCCUS GALLINARUM; ESCHERICHIA COLI; MUS;

EID: 80051737971     PISSN: 19490976     EISSN: 19490984     Source Type: Journal    
DOI: 10.4161/gmic.2.3.16104     Document Type: Article

References (42)

1. Sartor RB. Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. Nat Clin Pract Gastroenterol Hepatol 2006; 3:390-407.
2. Lupp C, Robertson ML, Wickham ME, Sekirov I, Champion OL, Gaynor EC, et al. Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe 2007; 2:119-29.
3. Frank DN, Robertson CE, Hamm CM, Kpadeh Z, Zhang T, Chen H, et al. Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases. Inflamm Bowel Dis 2010; 17:179-84.
4. Rehman A, Lepage P, Nolte A, Hellmig S, Schreiber S, Ott SJ. Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients. J Med Microbiol 2010; 59:1114-22.
5. Willing BP, Dicksved J, Halfvarson J, Andersson AF, Lucio M, Zheng Z, et al. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology 2010; 139:1844-54.
6. Wohlgemuth S, Haller D, Blaut M, Loh G. Reduced microbial diversity and high numbers of one single Escherichia coli strain in the intestine of colitic mice. Environ Microbiol 2009; 11:1562-71.
7. Heuman R, Sjodahl R, Tobiasson P, Tagesson C. Decreased absorption of ingested unconjugated chenodeoxycholic acid in patients with Crohn's disease. Scand J Gastroenterol 1983; 18:23-6.
8. Nyhlin H, Merrick MV, Eastwood MA. Bile acid malabsorption in Crohn's disease and indications for its assessment using SeHCAT. Gut 1994; 35:90-3.
9. Noh DO, Gilliland SE. Influence of bile on cellular integrity and beta-galactosidase activity of Lactobacillus acidophilus. J Dairy Sci 1993; 76:1253-9.
10. Bernstein C, Bernstein H, Payne CM, Beard SE, Schneider J. Bile salt activation of stress response promoters in Escherichia coli. Curr Microbiol 1999; 39:68-72.
11. Leverrier P, Dimova D, Pichereau V, Auffray Y, Boyaval P, Jan G. Susceptibility and adaptive response to bile salts in Propionibacterium freudenreichii: physiological and proteomic analysis. Appl Environ Microbiol 2003; 69:3809-18.
12. Floch MH, Binder HJ, Filburn B, Gershengoren W. The effect of bile acids on intestinal microflora. Am J Clin Nutr 1972; 25:1418-26.
13. Binder HJ, Filburn B, Floch M. Bile acid inhibition of intestinal anaerobic organisms. Am J Clin Nutr 1975; 28:119-25.
14. Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. J Lipid Res 2006; 47:241-59.
15. Berg DJ, Davidson N, Kuhn R, Muller W, Menon S, Holland G, et al. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J Clin Invest 1996; 98:1010-20.
16. Uronis JM, Muhlbauer M, Herfarth HH, Rubinas TC, Jones GS, Jobin C. Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility. PLoS One 2009; 4:6026.
17. Walker AW, Sanderson JD, Churcher C, Parkes GC, Hudspith BN, Rayment N, et al. High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease. BMC Microbiol 2011; 11:7.
18. Ye J, Lee JW, Presley LL, Bent E, Wei B, Braun J, et al. Bacteria and bacterial rRNA genes associated with the development of colitis in IL-10(-/-) mice. Inflamm Bowel Dis 2008; 14:1041-50.
19. Hakala K, Vuoristo M, Luukkonen P, Jarvinen HJ, Miettinen TA. Impaired absorption of cholesterol and bile acids in patients with an ileoanal anastomosis. Gut 1997; 41:771-7.
20. Hrabovsky V, Zadak Z, Blaha V, Hyspler R, Karlik T, Martinek A, et al. Cholesterol metabolism in active Crohn's disease. Wien Klin Wochenschr 2009; 121:270-5.
21. Kruis W, Kalek HD, Stellaard F, Paumgartner G. Altered fecal bile acid pattern in patients with inflammatory bowel disease. Digestion 1986; 35:189-98.
22. Ejderhamn J, Rafter JJ, Strandvik B. Faecal bile acid excretion in children with inflammatory bowel disease. Gut 1991; 32:1346-51.
23. Tamura M, Hori S, Nakagawa H. Dietary cholesterol lowers plasma and cecal equol concentrations in mice. Nutr Res 2009; 29:882-7.
24. Huang Y, Wang J, Cheng Y, Zheng Y. The hypocholesterolaemic effects of Lactobacillus acidophilus American type culture collection 4356 in rats are mediated by the downregulation of Niemann-Pick C1-like 1. Br J Nutr 2010; 104:807-12.
25. Veiga P, Juste C, Lepercq P, Saunier K, Beguet F, Gerard P. Correlation between faecal microbial community structure and cholesterol-to-coprostanol conversion in the human gut. FEMS Microbiol Lett 2005; 242:81-6.
26. Hashimoto S, Igimi H, Uchida K, Satoh T, Benno Y, Takeuchi N. Effects of beta-lactam antibiotics on intestinal microflora and bile acid metabolism in rats. Lipids 1996; 31:601-9.
27. Reddy BS, Wynder EL. Metabolic epidemiology of colon cancer. Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps. Cancer 1977; 39:2533-9.
28. Roy P, Owen RW, Faivre J, Scheppach W, Saldanha MH, Beckly DE, et al. Faecal neutral sterols and bile acids in patients with adenomas and large bowel cancer: an ECP case-control study. European cancer prevention. Eur J Cancer Prev 1999; 8:409-15.
29. Martinez-Augustin O, Sanchez de Medina F. Intestinal bile acid physiology and pathophysiology. World J Gastroenterol 2008; 14:5630-40.
30. Bernstein H, Bernstein C, Payne CM, Dvorak K. Bile acids as endogenous etiologic agents in gastrointestinal cancer. World J Gastroenterol 2009; 15:3329-40.
31. Katakura K, Lee J, Rachmilewitz D, Li G, Eckmann L, Raz E. Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J Clin Invest 2005; 115:695-702.
32. Keller S, Jahreis G. Determination of underivatised sterols and bile acid trimethyl silyl ether methyl esters by gas chromatography-mass spectrometry-single ion monitoring in faeces. J Chromatogr B Analyt Technol Biomed Life Sci 2004; 813:199-207.
33. Eyssen HJ, Parmentier GG, Mertens JA. Sulfate bile acids in germ-free and conventional mice. Eur J Biochem 1976; 66:507-14.
34. Wilson KH, Blitchington RB, Greene RC. Amplification of bacterial 16S ribosomal DNA with polymerase chain reaction. J Clin Microbiol 1990; 28:1942-6.
35. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990; 215:403-10.
36. Cole JR, Wang Q, Cardenas E, Fish J, Chai B, Farris RJ, et al. The Ribosomal Database Project: improved alignments and new tools for rRNA analysis. Nucleic Acids Res 2009; 37:141-5.
37. Amann RI, Ludwig W, Schleifer KH. Phylogenetic identification and in situ detection of individual microbial cells without cultivation. Microbiol Rev 1995; 59:143-69.
38. Sghir A, Gramet G, Suau A, Rochet V, Pochart P, Dore J. Quantification of bacterial groups within human fecal flora by oligonucleotide probe hybridization. Appl Environ Microbiol 2000; 66:2263-6.
39. Franks AH, Harmsen HJ, Raangs GC, Jansen GJ, Schut F, Welling GW. Variations of bacterial populations in human feces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes. Appl Environ Microbiol 1998; 64:3336-45.
40. Manz W, Amann R, Ludwig W, Vancanneyt M, Schleifer KH. Application of a suite of 16S rRNAspecific oligonucleotide probes designed to investigate bacteria of the phylum cytophaga-flavobacter-bacteroides in the natural environment. Microbiology 1996; 142:1097-106.
41. Harmsen D, Rothganger J, Singer C, Albert J, Frosch M. Intuitive hypertext-based molecular identification of micro-organisms. Lancet 1999; 353:291.
42. Thiel R, Blaut M. An improved method for the automated enumeration of fluorescently labelled bacteria in human faeces. J Microbiol Methods 2005; 61:369-79.