메뉴 건너뛰기




Volumn 5, Issue 1, 2011, Pages 1151-1165

Emerging nonsurgical methods for the treatment of vitreomacular adhesion: A review

Author keywords

Macular edema; Macular hole; Microplasmin; Pharmacologic vitreolysis; Posterior vitreous detachment; Vitreomacular traction syndrome

Indexed keywords

ALPHA 2 ANTIPLASMIN; ARGINYLGLYCYLASPARTIC ACID; CHONDROITIN SULFATE; COLLAGEN FIBRIL; COLLAGEN TYPE 18; COLLAGENASE; DISPASE; FIBRONECTIN; HYALURONIDASE; LAMININ; N ACETYLGALACTOSAMINE 4 SULFATASE; NATTOKINASE; OCRIPLASMIN; PLACEBO; PLASMIN; PLASMINOGEN; SERINE PROTEINASE; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; UREA DERIVATIVE; UROKINASE; VITREOSOLVE;

EID: 80051736296     PISSN: 11775467     EISSN: 11775483     Source Type: Journal    
DOI: 10.2147/opth.s14840     Document Type: Review
Times cited : (61)

References (162)
  • 1
    • 0025663637 scopus 로고
    • Role of posterior vitreous detachment in idiopathic macular holes
    • Akiba J, Quiroz MA, Trempe CL. Role of posterior vitreous detachment in idiopathic macular holes. Ophthalmology. 1990;97(12): 1610-1613.
    • (1990) Ophthalmology , vol.97 , Issue.12 , pp. 1610-1613
    • Akiba, J.1    Quiroz, M.A.2    Trempe, C.L.3
  • 2
    • 0014109785 scopus 로고
    • Vitreous traction at the posterior pole of the fundus due to alterations in the vitreous posterior
    • Jaffe NS. Vitreous traction at the posterior pole of the fundus due to alterations in the vitreous posterior. Trans Am Acad Ophthalmol Otolaryngol. 1967;71(4):642-652.
    • (1967) Trans Am Acad Ophthalmol Otolaryngol , vol.71 , Issue.4 , pp. 642-652
    • Jaffe, N.S.1
  • 3
    • 0024654679 scopus 로고
    • Macular edema and vitreous detachment
    • Roldan M, Serrano JM. Macular edema and vitreous detachment. Ann Ophthalmol. 1989;21(4):141-148.
    • (1989) Ann Ophthalmol , vol.21 , Issue.4 , pp. 141-148
    • Roldan, M.1    Serrano, J.M.2
  • 4
    • 0023814808 scopus 로고
    • The role of the vitreous in diabetic macular edema
    • Nasrallah FP, Jalkh AE, Van Coppenolle F, et al. The role of the vitreous in diabetic macular edema. Ophthalmology. 1988;95(10): 1335-1339.
    • (1988) Ophthalmology , vol.95 , Issue.10 , pp. 1335-1339
    • Nasrallah, F.P.1    Jalkh, A.E.2    van Coppenolle, F.3
  • 5
    • 0025360733 scopus 로고
    • Posterior vitreous detachment and neovascularization in diabetic retinopathy
    • Akiba J, Arzabe CW, Trempe CL. Posterior vitreous detachment and neovascularization in diabetic retinopathy. Ophthalmology. 1990;97(7): 889-891.
    • (1990) Ophthalmology , vol.97 , Issue.7 , pp. 889-891
    • Akiba, J.1    Arzabe, C.W.2    Trempe, C.L.3
  • 6
    • 0026075137 scopus 로고
    • Role of the vitreous in posterior segment neovascularization in central retinal vein occlusion
    • Akiba J, Kado M, Kakehashi A, Trempe CL. Role of the vitreous in posterior segment neovascularization in central retinal vein occlusion. Ophthalmic Surg. 1991;22(9):498-502.
    • (1991) Ophthalmic Surg , vol.22 , Issue.9 , pp. 498-502
    • Akiba, J.1    Kado, M.2    Kakehashi, A.3    Trempe, C.L.4
  • 7
    • 67349284037 scopus 로고    scopus 로고
    • Vitreomacular adhesion in active and end-stage age-related macular degeneration
    • Robison CD, Krebs I, Binder S, et al. Vitreomacular adhesion in active and end-stage age-related macular degeneration. Am J Ophthalmol. 2009;148(1):79-82. e72.
    • (2009) Am J Ophthalmol , vol.148 , Issue.1
    • Robison, C.D.1    Krebs, I.2    Binder, S.3
  • 8
    • 29944432408 scopus 로고    scopus 로고
    • Perifoveal vitreous detachment and its macular complications
    • Johnson MW. Perifoveal vitreous detachment and its macular complications. Trans Am Ophthalmol Soc. 2005;103:537-567.
    • (2005) Trans Am Ophthalmol Soc , vol.103 , pp. 537-567
    • Johnson, M.W.1
  • 9
    • 76749091926 scopus 로고    scopus 로고
    • Posterior vitreous detachment: Evolution and complications of its early stages
    • Johnson MW. Posterior vitreous detachment: evolution and complications of its early stages. Am J Ophthalmol. 2010;149(3):371-382. e371.
    • (2010) Am J Ophthalmol , vol.149 , Issue.3
    • Johnson, M.W.1
  • 11
    • 0030040922 scopus 로고    scopus 로고
    • Posterior vitreoschisis. An echographic finding in proliferative diabetic retinopathy
    • Chu TG, Lopez PF, Cano MR, et al. Posterior vitreoschisis. An echographic finding in proliferative diabetic retinopathy. Ophthalmology. 1996;103(2):315-322.
    • (1996) Ophthalmology , vol.103 , Issue.2 , pp. 315-322
    • Chu, T.G.1    Lopez, P.F.2    Cano, M.R.3
  • 13
    • 10744222273 scopus 로고    scopus 로고
    • Residual vitreous cortex after surgical posterior vitreous separation visualized by intravitreous triamcinolone acetonide
    • Sonoda KH, Sakamoto T, Enaida H, et al. Residual vitreous cortex after surgical posterior vitreous separation visualized by intravitreous triamcinolone acetonide. Ophthalmology. 2004;111(2): 226-230.
    • (2004) Ophthalmology , vol.111 , Issue.2 , pp. 226-230
    • Sonoda, K.H.1    Sakamoto, T.2    Enaida, H.3
  • 14
    • 0034767040 scopus 로고    scopus 로고
    • Optic disc, foveal, and extrafoveal damage due to surgical separation of the vitreous
    • Russell SR, Hageman GS. Optic disc, foveal, and extrafoveal damage due to surgical separation of the vitreous. Arch Ophthalmol. 2001; 119(11):1653-1658.
    • (2001) Arch Ophthalmol , vol.119 , Issue.11 , pp. 1653-1658
    • Russell, S.R.1    Hageman, G.S.2
  • 15
    • 0036196990 scopus 로고    scopus 로고
    • Plasmin-assisted vitrectomy eliminates cortical vitreous remnants
    • Gandorfer A, Ulbig M, Kampik A. Plasmin-assisted vitrectomy eliminates cortical vitreous remnants. Eye (Lond). 2002;16(1):95-97.
    • (2002) Eye (Lond) , vol.16 , Issue.1 , pp. 95-97
    • Gandorfer, A.1    Ulbig, M.2    Kampik, A.3
  • 16
    • 39149143784 scopus 로고    scopus 로고
    • Macular holes and macular pucker: The role of vitreoschisis as imaged by optical coherence tomography/scanning laser ophthalmoscopy
    • discussion 129-131
    • Sebag J, Gupta P, Rosen RR, Garcia P, Sadun AA. Macular holes and macular pucker: the role of vitreoschisis as imaged by optical coherence tomography/scanning laser ophthalmoscopy. Trans Am Ophthalmol Soc. 2007;105:121-129; discussion 129-131.
    • (2007) Trans Am Ophthalmol Soc , vol.105 , pp. 121-129
    • Sebag, J.1    Gupta, P.2    Rosen, R.R.3    Garcia, P.4    Sadun, A.A.5
  • 17
    • 0023740237 scopus 로고
    • Surgical excision of the attached posterior hyaloid
    • Han DP, Abrams GW, Aaberg TM. Surgical excision of the attached posterior hyaloid. Arch Ophthalmol. 1988;106(7):998-1000.
    • (1988) Arch Ophthalmol , vol.106 , Issue.7 , pp. 998-1000
    • Han, D.P.1    Abrams, G.W.2    Aaberg, T.M.3
  • 18
    • 0026685971 scopus 로고
    • A method for induction of posterior vitreous detachment during vitrectomy
    • Vander JF, Kleiner R. A method for induction of posterior vitreous detachment during vitrectomy. Retina. 1992;12(2):172-173.
    • (1992) Retina , vol.12 , Issue.2 , pp. 172-173
    • Vander, J.F.1    Kleiner, R.2
  • 19
    • 0035134383 scopus 로고    scopus 로고
    • Paracentral scotomata: A new finding after vitrectomy for idiopathic macular hole
    • Haritoglou C, Ehrt O, Gass CA, Kristin N, Kampik A. Paracentral scotomata: a new finding after vitrectomy for idiopathic macular hole. Br J Ophthalmol. 2001;85(2):231-233.
    • (2001) Br J Ophthalmol , vol.85 , Issue.2 , pp. 231-233
    • Haritoglou, C.1    Ehrt, O.2    Gass, C.A.3    Kristin, N.4    Kampik, A.5
  • 20
    • 0021234952 scopus 로고
    • Gas-mediated vitreous compression: An experimental alternative to mechanized vitrectomy
    • Thresher RJ, Ehrenberg M, Machemer R. Gas-mediated vitreous compression: an experimental alternative to mechanized vitrectomy. Graefes Arch Clin Exp Ophthalmol. 1984;221(5):192-198.
    • (1984) Graefes Arch Clin Exp Ophthalmol , vol.221 , Issue.5 , pp. 192-198
    • Thresher, R.J.1    Ehrenberg, M.2    McHemer, R.3
  • 21
    • 0021962869 scopus 로고
    • Experimental vitreous syneresis
    • Miller B, Miller H, Ryan SJ. Experimental vitreous syneresis. Arch Ophthalmol. 1985;103(9):1385-1388.
    • (1985) Arch Ophthalmol , vol.103 , Issue.9 , pp. 1385-1388
    • Miller, B.1    Miller, H.2    Ryan, S.J.3
  • 24
    • 33645230970 scopus 로고    scopus 로고
    • Induction of posterior vitreous separation using LASIK suction ring may have a potential role in the management of diabetic macular edema
    • Venkatesh P, Vajpayee RB, Garg S. Induction of posterior vitreous separation using LASIK suction ring may have a potential role in the management of diabetic macular edema. Med Hypotheses. 2006; 66(6):1137-1139.
    • (2006) Med Hypotheses , vol.66 , Issue.6 , pp. 1137-1139
    • Venkatesh, P.1    Vajpayee, R.B.2    Garg, S.3
  • 25
    • 0031614609 scopus 로고    scopus 로고
    • Pharmacologic vitreolysis
    • Sebag J. Pharmacologic vitreolysis. Retina. 1998;18(1):1-3.
    • (1998) Retina , vol.18 , Issue.1 , pp. 1-3
    • Sebag, J.1
  • 26
    • 0342681878 scopus 로고
    • Is your vitreous really necessary? The role of the vitreous in the eye with particular reference to retinal attachment, detachment and the mode of action of vitreous substitutes
    • Foulds WS. Is your vitreous really necessary? The role of the vitreous in the eye with particular reference to retinal attachment, detachment and the mode of action of vitreous substitutes. Eye (Lond). 1987; 1(Pt 6):641-664.
    • (1987) Eye (Lond) , vol.1 , Issue.PART 6 , pp. 641-664
    • Foulds, W.S.1
  • 27
    • 0034003134 scopus 로고    scopus 로고
    • Structural macromolecules and supramolecular organisation of the vitreous gel
    • Bishop PN. Structural macromolecules and supramolecular organisation of the vitreous gel. Prog Retin Eye Res. 2000;19(3): 323-344.
    • (2000) Prog Retin Eye Res , vol.19 , Issue.3 , pp. 323-344
    • Bishop, P.N.1
  • 28
    • 65249091452 scopus 로고    scopus 로고
    • The gel state of the vitreous and ascorbate-dependent oxygen consumption: Relationship to the etiology of nuclear cataracts
    • Shui YB, Holekamp NM, Kramer BC, et al. The gel state of the vitreous and ascorbate-dependent oxygen consumption: relationship to the etiology of nuclear cataracts. Arch Ophthalmol. 2009;127(4): 475-482.
    • (2009) Arch Ophthalmol , vol.127 , Issue.4 , pp. 475-482
    • Shui, Y.B.1    Holekamp, N.M.2    Kramer, B.C.3
  • 29
    • 72049123996 scopus 로고    scopus 로고
    • The vitreous gel: More than meets the eye
    • Holekamp NM. The vitreous gel: more than meets the eye. Am J Ophthalmol. 2010;149(1):32-36.
    • (2010) Am J Ophthalmol , vol.149 , Issue.1 , pp. 32-36
    • Holekamp, N.M.1
  • 30
    • 73349092809 scopus 로고    scopus 로고
    • Vitreous as a substrate for vitreolysis
    • Bishop PN. Vitreous as a substrate for vitreolysis. Dev Ophthalmol. 2009;44:7-19.
    • (2009) Dev Ophthalmol , vol.44 , pp. 7-19
    • Bishop, P.N.1
  • 32
    • 0022578374 scopus 로고
    • Structure and composition of the inner limiting membrane of the retina. SEM on frozen resin-cracked and enzyme-digested retinas of Macaca mulatta
    • Heegaard S, Jensen OA, Prause JU. Structure and composition of the inner limiting membrane of the retina. SEM on frozen resin-cracked and enzyme-digested retinas of Macaca mulatta. Graefes Arch Clin Exp Ophthalmol. 1986;224(4):355-360.
    • (1986) Graefes Arch Clin Exp Ophthalmol , vol.224 , Issue.4 , pp. 355-360
    • Heegaard, S.1    Jensen, O.A.2    Prause, J.U.3
  • 35
    • 0024407627 scopus 로고
    • Morphology and ultrastructure of human vitreous fibers
    • Sebag J, Balazs EA. Morphology and ultrastructure of human vitreous fibers. Invest Ophthalmol Vis Sci. 1989;30(8):1867-1871.
    • (1989) Invest Ophthalmol Vis Sci , vol.30 , Issue.8 , pp. 1867-1871
    • Sebag, J.1    Balazs, E.A.2
  • 36
    • 0015418223 scopus 로고
    • Vitreoretinal juncture; topographical variations
    • Foos RY. Vitreoretinal juncture; topographical variations. Invest Ophthalmol. 1972;11(10):801-808.
    • (1972) Invest Ophthalmol , vol.11 , Issue.10 , pp. 801-808
    • Foos, R.Y.1
  • 38
    • 29944443425 scopus 로고    scopus 로고
    • Molecular biology of pharmacologic vitreolysis
    • Sebag J. Molecular biology of pharmacologic vitreolysis. Trans Am Ophthalmol Soc. 2005;103:473-494.
    • (2005) Trans Am Ophthalmol Soc , vol.103 , pp. 473-494
    • Sebag, J.1
  • 39
    • 0019164990 scopus 로고
    • Role of laminin in the attachment of PAM 212 (epithelial) cells to basement membrane collagen
    • Terranova VP, Rohrbach DH, Martin GR. Role of laminin in the attachment of PAM 212 (epithelial) cells to basement membrane collagen. Cell. 1980;22(3):719-726.
    • (1980) Cell , vol.22 , Issue.3 , pp. 719-726
    • Terranova, V.P.1    Rohrbach, D.H.2    Martin, G.R.3
  • 40
    • 0018185067 scopus 로고
    • Affinity of fibronectin to collagens of different genetic types and to fibrinogen
    • Engvall E, Ruoslahti E, Miller EJ. Affinity of fibronectin to collagens of different genetic types and to fibrinogen. J Exp Med. 1978; 147(6):1584-1595.
    • (1978) J Exp Med , vol.147 , Issue.6 , pp. 1584-1595
    • Engvall, E.1    Ruoslahti, E.2    Miller, E.J.3
  • 41
    • 0020411289 scopus 로고
    • Vitreoretinal juncture. Synchysis senilis and posterior vitreous detachment
    • Foos RY, Wheeler NC. Vitreoretinal juncture. Synchysis senilis and posterior vitreous detachment. Ophthalmology. 1982;89(12):1502-1512.
    • (1982) Ophthalmology , vol.89 , Issue.12 , pp. 1502-1512
    • Foos, R.Y.1    Wheeler, N.C.2
  • 43
    • 0025308991 scopus 로고
    • Posterior precortical vitreous pocket
    • Kishi S, Shimizu K. Posterior precortical vitreous pocket. Arch Ophthalmol. 1990;108(7):979-982.
    • (1990) Arch Ophthalmol , vol.108 , Issue.7 , pp. 979-982
    • Kishi, S.1    Shimizu, K.2
  • 44
    • 0023120523 scopus 로고
    • Age-related changes in human vitreous structure
    • Sebag J. Age-related changes in human vitreous structure. Graefes Arch Clin Exp Ophthalmol. 1987;225(2):89-93.
    • (1987) Graefes Arch Clin Exp Ophthalmol , vol.225 , Issue.2 , pp. 89-93
    • Sebag, J.1
  • 45
    • 0002996414 scopus 로고
    • The pattern of vitreous syneresis: A study of 800 autopsy eyes
    • In: Irvine AR, O'Malley C, editors, Springfield, IL: Thomas
    • O'Malley P. The pattern of vitreous syneresis: a study of 800 autopsy eyes. In: Irvine AR, O'Malley C, editors. Advances in vitreous surgery. Springfield, IL: Thomas; 1976:17-33.
    • (1976) Advances in vitreous surgery , pp. 17-33
    • O'Malley, P.1
  • 46
    • 0021795259 scopus 로고
    • Posterior vitreous detachment. A combined clinical and physiochemical study
    • Larsson L, Osterlin S. Posterior vitreous detachment. A combined clinical and physiochemical study. Graefes Arch Clin Exp Ophthalmol. 1985;223(2):92-95.
    • (1985) Graefes Arch Clin Exp Ophthalmol , vol.223 , Issue.2 , pp. 92-95
    • Larsson, L.1    Osterlin, S.2
  • 47
    • 0002121171 scopus 로고
    • Acute posterior vitreous detachment and its retinal complications
    • Linder B. Acute posterior vitreous detachment and its retinal complications. Acta Ophthalmol. 1966;87(Suppl):1-108.
    • (1966) Acta Ophthalmol , vol.87 , Issue.SUPPL. , pp. 1-108
    • Linder, B.1
  • 48
    • 4544323408 scopus 로고    scopus 로고
    • Anomalous posterior vitreous detachment: A unifying concept in vitreo-retinal disease
    • Sebag J. Anomalous posterior vitreous detachment: a unifying concept in vitreo-retinal disease. Graefes Arch Clin Exp Ophthalmol. 2004;242(8):690-698.
    • (2004) Graefes Arch Clin Exp Ophthalmol , vol.242 , Issue.8 , pp. 690-698
    • Sebag, J.1
  • 49
    • 85046515344 scopus 로고
    • Experimental occlusion of retinal and ciliary vessels in owl monkeys. I. Technique and clinical observations of selective embolism of the central retinal artery system
    • Kloti R. Experimental occlusion of retinal and ciliary vessels in owl monkeys. I. Technique and clinical observations of selective embolism of the central retinal artery system. Exp Eye Res. 1967;6(4): 393-399.
    • (1967) Exp Eye Res , vol.6 , Issue.4 , pp. 393-399
    • Kloti, R.1
  • 50
    • 0025865762 scopus 로고
    • Age-related differences in the human vitreoretinal interface
    • Sebag J. Age-related differences in the human vitreoretinal interface. Arch Ophthalmol. 1991;109(7):966-971.
    • (1991) Arch Ophthalmol , vol.109 , Issue.7 , pp. 966-971
    • Sebag, J.1
  • 51
    • 0036485196 scopus 로고    scopus 로고
    • Is pharmacologic vitreolysis brewing?
    • Sebag J. Is pharmacologic vitreolysis brewing? Retina. 2002;22(1):1-3.
    • (2002) Retina , vol.22 , Issue.1 , pp. 1-3
    • Sebag, J.1
  • 52
    • 0023266102 scopus 로고
    • Effects of visible-light irradiation on vitreous structure in the presence of a photosensitizer
    • Ueno N, Sebag J, Hirokawa H, Chakrabarti B. Effects of visible-light irradiation on vitreous structure in the presence of a photosensitizer. Exp Eye Res. 1987;44(6):863-870.
    • (1987) Exp Eye Res , vol.44 , Issue.6 , pp. 863-870
    • Ueno, N.1    Sebag, J.2    Hirokawa, H.3    Chakrabarti, B.4
  • 53
    • 0028291538 scopus 로고
    • Mechanisms of photo-induced vitreous liquefaction
    • Akiba J, Ueno N, Chakrabarti B. Mechanisms of photo-induced vitreous liquefaction. Curr Eye Res. 1994;13(7):505-512.
    • (1994) Curr Eye Res , vol.13 , Issue.7 , pp. 505-512
    • Akiba, J.1    Ueno, N.2    Chakrabarti, B.3
  • 54
    • 0028078744 scopus 로고
    • Molecular mechanisms of photochemically induced posterior vitreous detachment
    • Kakehashi A, Ueno N, Chakrabarti B. Molecular mechanisms of photochemically induced posterior vitreous detachment. Ophthalmic Res. 1994;26(1):51-59.
    • (1994) Ophthalmic Res , vol.26 , Issue.1 , pp. 51-59
    • Kakehashi, A.1    Ueno, N.2    Chakrabarti, B.3
  • 55
    • 0029996393 scopus 로고    scopus 로고
    • Cleavage of structural components of mammalian vitreous by endogenous matrix metalloproteinase-2
    • Brown DJ, Bishop P, Hamdi H, Kenney MC. Cleavage of structural components of mammalian vitreous by endogenous matrix metalloproteinase-2. Curr Eye Res. 1996;15(4):439-445.
    • (1996) Curr Eye Res , vol.15 , Issue.4 , pp. 439-445
    • Brown, D.J.1    Bishop, P.2    Hamdi, H.3    Kenney, M.C.4
  • 56
    • 0033781834 scopus 로고    scopus 로고
    • Elevated levels of proteolytic enzymes in the aging human vitreous
    • Vaughan-Thomas A, Gilbert SJ, Duance VC. Elevated levels of proteolytic enzymes in the aging human vitreous. Invest Ophthalmol Vis Sci. 2000;41(11):3299-3304.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.11 , pp. 3299-3304
    • Vaughan-Thomas, A.1    Gilbert, S.J.2    Duance, V.C.3
  • 57
    • 0038239154 scopus 로고    scopus 로고
    • Age-related liquefaction of the human vitreous body: LM and TEM evaluation of the role of proteoglycans and collagen
    • Los LI, van der Worp RJ, van Luyn MJ, Hooymans JM. Age-related liquefaction of the human vitreous body: LM and TEM evaluation of the role of proteoglycans and collagen. Invest Ophthalmol Vis Sci. 2003; 44(7):2828-2833.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , Issue.7 , pp. 2828-2833
    • Los, L.I.1    van der Worp, R.J.2    van Luyn, M.J.3    Hooymans, J.M.4
  • 58
    • 0020665169 scopus 로고
    • Enzyme-assisted vitrectomy with bacterial collagenase. Time course and toxicity studies
    • Moorhead LC, Chu HH, Garcia CA. Enzyme-assisted vitrectomy with bacterial collagenase. Time course and toxicity studies. Arch Ophthalmol. 1983;101(2):265-274.
    • (1983) Arch Ophthalmol , vol.101 , Issue.2 , pp. 265-274
    • Moorhead, L.C.1    Chu, H.H.2    Garcia, C.A.3
  • 59
    • 0022262631 scopus 로고
    • Enzyme-assisted vitrectomy with bacterial collagenase. Pilot human studies
    • Moorhead LC, Radtke N. Enzyme-assisted vitrectomy with bacterial collagenase. Pilot human studies. Retina. 1985;5(2):98-100.
    • (1985) Retina , vol.5 , Issue.2 , pp. 98-100
    • Moorhead, L.C.1    Radtke, N.2
  • 60
    • 0018935664 scopus 로고
    • Bacterial collagenase. Proposed adjunct to vitrectomy with membranectomy
    • Moorhead LC, Redburn DA, Kirkpatrick DS, Kretzer F. Bacterial collagenase. Proposed adjunct to vitrectomy with membranectomy. Arch Ophthalmol. 1980;98(10):1829-1839.
    • (1980) Arch Ophthalmol , vol.98 , Issue.10 , pp. 1829-1839
    • Moorhead, L.C.1    Redburn, D.A.2    Kirkpatrick, D.S.3    Kretzer, F.4
  • 62
    • 0031906521 scopus 로고    scopus 로고
    • Efficacy and safety of enzymatic posterior vitreous detachment by intravitreal injection of hyaluronidase
    • Harooni M, McMillan T, Refojo M. Efficacy and safety of enzymatic posterior vitreous detachment by intravitreal injection of hyaluronidase. Retina. 1998;18(1):16-22.
    • (1998) Retina , vol.18 , Issue.1 , pp. 16-22
    • Harooni, M.1    McMillan, T.2    Refojo, M.3
  • 63
    • 0031884777 scopus 로고    scopus 로고
    • Posterior vitreous detachment with dispase
    • Tezel TH, Del Priore LV, Kaplan HJ. Posterior vitreous detachment with dispase. Retina. 1998;18(1):7-15.
    • (1998) Retina , vol.18 , Issue.1 , pp. 7-15
    • Tezel, T.H.1    del Priore, L.V.2    Kaplan, H.J.3
  • 64
    • 0036327144 scopus 로고    scopus 로고
    • Enzymatic-assisted vitrectomy
    • Trese MT. Enzymatic-assisted vitrectomy. Eye (Lond). 2002;16(4): 365-368.
    • (2002) Eye (Lond) , vol.16 , Issue.4 , pp. 365-368
    • Trese, M.T.1
  • 65
    • 0034095773 scopus 로고    scopus 로고
    • Enzymatic vitreous surgery
    • Trese MT. Enzymatic vitreous surgery. Semin Ophthalmol. 2000;15(2): 116-121.
    • (2000) Semin Ophthalmol , vol.15 , Issue.2 , pp. 116-121
    • Trese, M.T.1
  • 66
    • 33947499496 scopus 로고    scopus 로고
    • Pharmacologic vitreolysis
    • Gandorfer A. Pharmacologic vitreolysis. Dev Ophthalmol. 2007;39: 149-156.
    • (2007) Dev Ophthalmol , vol.39 , pp. 149-156
    • Gandorfer, A.1
  • 67
    • 54249136755 scopus 로고    scopus 로고
    • Enzymatic vitreous disruption
    • Gandorfer A. Enzymatic vitreous disruption. Eye (Lond). 2008;22(10): 1273-1277.
    • (2008) Eye (Lond) , vol.22 , Issue.10 , pp. 1273-1277
    • Gandorfer, A.1
  • 68
    • 0035167501 scopus 로고    scopus 로고
    • Anticipation for enzymatic vitreolysis
    • Bhisitkul RB. Anticipation for enzymatic vitreolysis. Br J Ophthalmol. 2001;85(1):1-2.
    • (2001) Br J Ophthalmol , vol.85 , Issue.1 , pp. 1-2
    • Bhisitkul, R.B.1
  • 69
    • 77949656341 scopus 로고    scopus 로고
    • A placebo-controlled trial of microplasmin intravitreous injection to facilitate posterior vitreous detachment before vitrectomy
    • Benz MS, Packo KH, Gonzalez V, et al. A placebo-controlled trial of microplasmin intravitreous injection to facilitate posterior vitreous detachment before vitrectomy. Ophthalmology. 2010;117(4): 791-797.
    • (2010) Ophthalmology , vol.117 , Issue.4 , pp. 791-797
    • Benz, M.S.1    Packo, K.H.2    Gonzalez, V.3
  • 70
    • 59749087380 scopus 로고    scopus 로고
    • Effect of intravitreal plasmin on vitreous removal through a 25-gauge cutting system in the rabbit in vivo
    • Hermel M, Prenner J, Alabdulrazzak M, Dailey W, Hartzer M. Effect of intravitreal plasmin on vitreous removal through a 25-gauge cutting system in the rabbit in vivo. Graefes Arch Clin Exp Ophthalmol. 2009; 247(3):331-334.
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , Issue.3 , pp. 331-334
    • Hermel, M.1    Prenner, J.2    Alabdulrazzak, M.3    Dailey, W.4    Hartzer, M.5
  • 71
    • 14944339159 scopus 로고    scopus 로고
    • Transconjunctival sutureless 23-gauge vitrectomy
    • Eckardt C. Transconjunctival sutureless 23-gauge vitrectomy. Retina. 2005;25(2):208-211.
    • (2005) Retina , vol.25 , Issue.2 , pp. 208-211
    • Eckardt, C.1
  • 72
    • 0036787692 scopus 로고    scopus 로고
    • A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery
    • discussion 1813
    • Fujii GY, De Juan E Jr, Humayun MS, et al. A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery. Ophthalmology. 2002;109(10):1807-1812; discussion 1813.
    • (2002) Ophthalmology , vol.109 , Issue.10 , pp. 1807-1812
    • Fujii, G.Y.1    de Juan Jr., E.2    Humayun, M.S.3
  • 73
    • 77956344215 scopus 로고    scopus 로고
    • Risk of iatrogenic peripheral retinal breaks in 20-G pars plana vitrectomy
    • Ramkissoon YD, Aslam SA, Shah SP, Wong SC, Sullivan PM. Risk of iatrogenic peripheral retinal breaks in 20-G pars plana vitrectomy. Ophthalmology. 2010;117(9):1825-1830.
    • (2010) Ophthalmology , vol.117 , Issue.9 , pp. 1825-1830
    • Ramkissoon, Y.D.1    Aslam, S.A.2    Shah, S.P.3    Wong, S.C.4    Sullivan, P.M.5
  • 74
    • 68949126725 scopus 로고    scopus 로고
    • Iatrogenic retinal breaks in 25-gauge macular surgery
    • Tan HS, Mura M, de Smet MD. Iatrogenic retinal breaks in 25-gauge macular surgery. Am J Ophthalmol. 2009;148(3):427-430.
    • (2009) Am J Ophthalmol , vol.148 , Issue.3 , pp. 427-430
    • Tan, H.S.1    Mura, M.2    de Smet, M.D.3
  • 75
    • 42449096490 scopus 로고    scopus 로고
    • 20-, 23-, and 25-gauge vitreous cutters: Performance and characteristics evaluation
    • Hubschman JP, Gupta A, Bourla DH, Culjat M, Yu F, Schwartz SD. 20-, 23-, and 25-gauge vitreous cutters: performance and characteristics evaluation. Retina. 2008;28(2):249-257.
    • (2008) Retina , vol.28 , Issue.2 , pp. 249-257
    • Hubschman, J.P.1    Gupta, A.2    Bourla, D.H.3    Culjat, M.4    Yu, F.5    Schwartz, S.D.6
  • 76
    • 77954348925 scopus 로고    scopus 로고
    • Vitreoretinal traction created by conventional cutters during vitrectomy
    • Teixeira A, Chong LP, Matsuoka N, et al. Vitreoretinal traction created by conventional cutters during vitrectomy. Ophthalmology. 2010; 117(7):1387-1392. e1382.
    • (2010) Ophthalmology , vol.117 , Issue.7
    • Teixeira, A.1    Chong, L.P.2    Matsuoka, N.3
  • 77
    • 0842267257 scopus 로고    scopus 로고
    • Ultrastructure of internal limiting membrane removed during plasmin-assisted vitrectomy from eyes with diabetic macular edema
    • Asami T, Terasaki H, Kachi S, et al. Ultrastructure of internal limiting membrane removed during plasmin-assisted vitrectomy from eyes with diabetic macular edema. Ophthalmology. 2004;111(2):231-237.
    • (2004) Ophthalmology , vol.111 , Issue.2 , pp. 231-237
    • Asami, T.1    Terasaki, H.2    Kachi, S.3
  • 78
    • 0023923895 scopus 로고
    • The development of severe proliferative vitreoretinopathy after retinal detachment surgery. Grade B: A determining risk factor
    • Bonnet M. The development of severe proliferative vitreoretinopathy after retinal detachment surgery. Grade B: a determining risk factor. Graefes Arch Clin Exp Ophthalmol. 1988;226(3):201-205.
    • (1988) Graefes Arch Clin Exp Ophthalmol , vol.226 , Issue.3 , pp. 201-205
    • Bonnet, M.1
  • 79
    • 0031866565 scopus 로고    scopus 로고
    • Comparative study of incomplete posterior vitreous detachment as a risk factor for proliferative vitreoretinopathy
    • Capeans C, Lorenzo J, Santos L, et al. Comparative study of incomplete posterior vitreous detachment as a risk factor for proliferative vitreoretinopathy. Graefes Arch Clin Exp Ophthalmol. 1998;236(7):481-485.
    • (1998) Graefes Arch Clin Exp Ophthalmol , vol.236 , Issue.7 , pp. 481-485
    • Capeans, C.1    Lorenzo, J.2    Santos, L.3
  • 80
    • 17144424659 scopus 로고    scopus 로고
    • Epiretinal pathology of diffuse diabetic macular edema associated with vitreomacular traction
    • Gandorfer A, Rohleder M, Grosselfinger S, Haritoglou C, Ulbig M, Kampik A. Epiretinal pathology of diffuse diabetic macular edema associated with vitreomacular traction. Am J Ophthalmol. 2005; 139(4):638-652.
    • (2005) Am J Ophthalmol , vol.139 , Issue.4 , pp. 638-652
    • Gandorfer, A.1    Rohleder, M.2    Grosselfinger, S.3    Haritoglou, C.4    Ulbig, M.5    Kampik, A.6
  • 81
    • 0019352782 scopus 로고
    • Vitreoretinal relationship in diabetic retinopathy. A biomicroscopic evaluation
    • Takahashi M, Trempe CL, Maguire K, McMeel JW. Vitreoretinal relationship in diabetic retinopathy. A biomicroscopic evaluation. Arch Ophthalmol. 1981;99(2):241-245.
    • (1981) Arch Ophthalmol , vol.99 , Issue.2 , pp. 241-245
    • Takahashi, M.1    Trempe, C.L.2    Maguire, K.3    McMeel, J.W.4
  • 83
    • 0023880319 scopus 로고
    • Role of the vitreous in branch retinal vein occlusion
    • Kado M, Trempe CL. Role of the vitreous in branch retinal vein occlusion. Am J Ophthalmol. 1988;105(1):20-24.
    • (1988) Am J Ophthalmol , vol.105 , Issue.1 , pp. 20-24
    • Kado, M.1    Trempe, C.L.2
  • 84
    • 0028832044 scopus 로고
    • Role of the vitreous in central retinal vein occlusion
    • Hikichi T, Konno S, Trempe CL. Role of the vitreous in central retinal vein occlusion. Retina. 1995;15(1):29-33.
    • (1995) Retina , vol.15 , Issue.1 , pp. 29-33
    • Hikichi, T.1    Konno, S.2    Trempe, C.L.3
  • 85
    • 0030733161 scopus 로고    scopus 로고
    • The effect of posterior vitreous detachment on the prognosis of branch retinal vein occlusion
    • Avunduk AM, Cetinkaya K, Kapicioglu Z, Kaya C. The effect of posterior vitreous detachment on the prognosis of branch retinal vein occlusion. Acta Ophthalmol Scand. 1997;75(4):441-442.
    • (1997) Acta Ophthalmol Scand , vol.75 , Issue.4 , pp. 441-442
    • Avunduk, A.M.1    Cetinkaya, K.2    Kapicioglu, Z.3    Kaya, C.4
  • 86
    • 35349014156 scopus 로고    scopus 로고
    • Posterior vitreomacular adhesion: A potential risk factor for exudative age-related macular degeneration?
    • Krebs I, Brannath W, Glittenberg C, Zeiler F, Sebag J, Binder S. Posterior vitreomacular adhesion: a potential risk factor for exudative age-related macular degeneration? Am J Ophthalmol. 2007;144(5):741-746.
    • (2007) Am J Ophthalmol , vol.144 , Issue.5 , pp. 741-746
    • Krebs, I.1    Brannath, W.2    Glittenberg, C.3    Zeiler, F.4    Sebag, J.5    Binder, S.6
  • 87
    • 62649174079 scopus 로고    scopus 로고
    • Posterior vitreomacular adhesion and risk of exudative age-related macular degeneration: Paired eye study
    • Lee SJ, Lee CS, Koh HJ. Posterior vitreomacular adhesion and risk of exudative age-related macular degeneration: paired eye study. Am J Ophthalmol. 2009;147(4):621-626. e621.
    • (2009) Am J Ophthalmol , vol.147 , Issue.4
    • Lee, S.J.1    Lee, C.S.2    Koh, H.J.3
  • 88
    • 26844520874 scopus 로고    scopus 로고
    • Pooled efficacy results from two multinational randomized controlled clinical trials of a single intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage
    • Kuppermann BD, Thomas EL, de Smet MD, Grillone LR. Pooled efficacy results from two multinational randomized controlled clinical trials of a single intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage. Am J Ophthalmol. 2005;140(4):573-584.
    • (2005) Am J Ophthalmol , vol.140 , Issue.4 , pp. 573-584
    • Kuppermann, B.D.1    Thomas, E.L.2    de Smet, M.D.3    Grillone, L.R.4
  • 89
    • 26844577329 scopus 로고    scopus 로고
    • Safety results of two phase III trials of an intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage
    • Kuppermann BD, Thomas EL, de Smet MD, Grillone LR. Safety results of two phase III trials of an intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage. Am J Ophthalmol. 2005;140(4):585-597.
    • (2005) Am J Ophthalmol , vol.140 , Issue.4 , pp. 585-597
    • Kuppermann, B.D.1    Thomas, E.L.2    de Smet, M.D.3    Grillone, L.R.4
  • 90
    • 68249124041 scopus 로고    scopus 로고
    • Pharmacologic vitreolysis-premise and promise of the first decade
    • Sebag J. Pharmacologic vitreolysis-premise and promise of the first decade. Retina. 2009;29(7):871-874.
    • (2009) Retina , vol.29 , Issue.7 , pp. 871-874
    • Sebag, J.1
  • 91
    • 37049244855 scopus 로고
    • Collagenase
    • Mandl I. Collagenase. Science. 1970;169(951):1234-1238.
    • (1970) Science , vol.169 , Issue.951 , pp. 1234-1238
    • Mandl, I.1
  • 92
    • 0015608738 scopus 로고
    • The effects of bacterial collagenase in rabbit vitreous
    • O'Neill R, Shea M. The effects of bacterial collagenase in rabbit vitreous. Can J Ophthalmol. 1973;8(2):366-370.
    • (1973) Can J Ophthalmol , vol.8 , Issue.2 , pp. 366-370
    • O'Neill, R.1    Shea, M.2
  • 95
    • 0000598037 scopus 로고
    • Chondroitinase-mediated disinsertion of the primate vitreous body [abstract]
    • Hageman GS, Russell SR. Chondroitinase-mediated disinsertion of the primate vitreous body [abstract]. Invest Ophthalmol Vis Sci (Suppl). 1994;35:1260.
    • (1994) Invest Ophthalmol Vis Sci (Suppl) , vol.35 , pp. 1260
    • Hageman, G.S.1    Russell, S.R.2
  • 96
    • 0032840481 scopus 로고    scopus 로고
    • Effects of hyaluronan lyase, hyaluronidase, and chondroitin ABC lyase on mammalian vitreous gel
    • Bishop PN, McLeod D, Reardon A. Effects of hyaluronan lyase, hyaluronidase, and chondroitin ABC lyase on mammalian vitreous gel. Invest Ophthalmol Vis Sci. 1999;40(10):2173-2178.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.10 , pp. 2173-2178
    • Bishop, P.N.1    McLeod, D.2    Reardon, A.3
  • 97
    • 11844280358 scopus 로고    scopus 로고
    • Enzyme-assisted vitrectomy in enucleated pig eyes: A comparison of hyaluronidase, chondroitinase, and plasmin
    • Staubach F, Nober V, Janknecht P. Enzyme-assisted vitrectomy in enucleated pig eyes: a comparison of hyaluronidase, chondroitinase, and plasmin. Curr Eye Res. 2004;29(4-5):261-268.
    • (2004) Curr Eye Res , vol.29 , Issue.4-5 , pp. 261-268
    • Staubach, F.1    Nober, V.2    Janknecht, P.3
  • 98
    • 33947159768 scopus 로고    scopus 로고
    • Efficacy of plasmin enzymes and chondroitinase ABC in creating posterior vitreous separation in the pig: A masked, placebo-controlled in vivo study
    • Hermel M, Schrage NF. Efficacy of plasmin enzymes and chondroitinase ABC in creating posterior vitreous separation in the pig: a masked, placebo-controlled in vivo study. Graefes Arch Clin Exp Ophthalmol. 2007;245(3):399-406.
    • (2007) Graefes Arch Clin Exp Ophthalmol , vol.245 , Issue.3 , pp. 399-406
    • Hermel, M.1    Schrage, N.F.2
  • 99
  • 100
    • 0032508626 scopus 로고    scopus 로고
    • Hyaluronidase and its substrate hyaluronan: Biochemistry, biological activities and therapeutic uses
    • Menzel EJ, Farr C. Hyaluronidase and its substrate hyaluronan: biochemistry, biological activities and therapeutic uses. Cancer Lett. 1998;131(1):3-11.
    • (1998) Cancer Lett , vol.131 , Issue.1 , pp. 3-11
    • Menzel, E.J.1    Farr, C.2
  • 101
    • 0021879369 scopus 로고
    • Effect of intravitreal hyaluronidase on the clearance of tritiated water from the vitreous to the choroid
    • Foulds WS, Allan D, Moseley H, Kyle PM. Effect of intravitreal hyaluronidase on the clearance of tritiated water from the vitreous to the choroid. Br J Ophthalmol. 1985;69(7):529-532.
    • (1985) Br J Ophthalmol , vol.69 , Issue.7 , pp. 529-532
    • Foulds, W.S.1    Allan, D.2    Moseley, H.3    Kyle, P.M.4
  • 103
    • 0029432549 scopus 로고
    • Induction of vitreolysis and vitreous detachment with hyaluronidase and perfluoropropane gas
    • Kang SW, Hyung SM, Choi MY, Lee J. Induction of vitreolysis and vitreous detachment with hyaluronidase and perfluoropropane gas. Korean J Ophthalmol. 1995;9(2):69-78.
    • (1995) Korean J Ophthalmol , vol.9 , Issue.2 , pp. 69-78
    • Kang, S.W.1    Hyung, S.M.2    Choi, M.Y.3    Lee, J.4
  • 104
    • 0034091296 scopus 로고    scopus 로고
    • Intravitreal injection of hyaluronidase cannot induce posterior vitreous detachment in the rabbit
    • Hikichi T, Kado M, Yoshida A. Intravitreal injection of hyaluronidase cannot induce posterior vitreous detachment in the rabbit. Retina. 2000; 20(2):195-198.
    • (2000) Retina , vol.20 , Issue.2 , pp. 195-198
    • Hikichi, T.1    Kado, M.2    Yoshida, A.3
  • 105
    • 13844251851 scopus 로고    scopus 로고
    • PVD following plasmin but not hyaluronidase: Implications for combination pharmacologic vitreolysis therapy
    • Wang Z-L, Zhang X, Xu X, Sun X-D, Wang F. PVD following plasmin but not hyaluronidase: implications for combination pharmacologic vitreolysis therapy. Retina. 2005;25(1):38-43.
    • (2005) Retina , vol.25 , Issue.1 , pp. 38-43
    • Wang, Z.-L.1    Zhang, X.2    Xu, X.3    Sun, X.-D.4    Wang, F.5
  • 106
    • 0024400858 scopus 로고
    • Dispase, a neutral protease from Bacillus polymyxa, is a powerful fibronectinase and type IV collagenase
    • Stenn KS, Link R, Moellmann G, Madri J, Kuklinska E. Dispase, a neutral protease from Bacillus polymyxa, is a powerful fibronectinase and type IV collagenase. J Invest Dermatol. 1989;93(2):287-290.
    • (1989) J Invest Dermatol , vol.93 , Issue.2 , pp. 287-290
    • Stenn, K.S.1    Link, R.2    Moellmann, G.3    Madri, J.4    Kuklinska, E.5
  • 108
    • 33745436484 scopus 로고    scopus 로고
    • Experimental model for proliferative vitreoretinopathy by intravitreal dispase: Limited by zonulolysis and cataract
    • Kralinger MT, Kieselbach GF, Voigt M, et al. Experimental model for proliferative vitreoretinopathy by intravitreal dispase: limited by zonulolysis and cataract. Ophthalmologica. 2006;220(4): 211-216.
    • (2006) Ophthalmologica , vol.220 , Issue.4 , pp. 211-216
    • Kralinger, M.T.1    Kieselbach, G.F.2    Voigt, M.3
  • 110
  • 111
    • 33751182096 scopus 로고    scopus 로고
    • Effects of intravitreal dispase on vitreoretinal interface in rabbits
    • Zhu D, Chen H, Xu X. Effects of intravitreal dispase on vitreoretinal interface in rabbits. Curr Eye Res. 2006;31(11):935-946.
    • (2006) Curr Eye Res , vol.31 , Issue.11 , pp. 935-946
    • Zhu, D.1    Chen, H.2    Xu, X.3
  • 112
    • 4344580726 scopus 로고    scopus 로고
    • Safety and efficacy of dispase and plasmin in pharmacologic vitreolysis
    • Wang F, Wang Z, Sun X, Xu X, Zhang X. Safety and efficacy of dispase and plasmin in pharmacologic vitreolysis. Invest Ophthalmol Vis Sci. 2004;45(9):3286-3290.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.9 , pp. 3286-3290
    • Wang, F.1    Wang, Z.2    Sun, X.3    Xu, X.4    Zhang, X.5
  • 113
    • 0023656415 scopus 로고
    • A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet
    • Sumi H, Hamada H, Tsushima H, Mihara H, Muraki H. A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet. Experientia. 1987;43(10):1110-1111.
    • (1987) Experientia , vol.43 , Issue.10 , pp. 1110-1111
    • Sumi, H.1    Hamada, H.2    Tsushima, H.3    Mihara, H.4    Muraki, H.5
  • 114
    • 0025134853 scopus 로고
    • Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase
    • Sumi H, Hamada H, Nakanishi K, Hiratani H. Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol. 1990;84(3):139-143.
    • (1990) Acta Haematol , vol.84 , Issue.3 , pp. 139-143
    • Sumi, H.1    Hamada, H.2    Nakanishi, K.3    Hiratani, H.4
  • 115
    • 0035816636 scopus 로고    scopus 로고
    • The profibrinolytic enzyme subtilisin NAT purified from Bacillus subtilis Cleaves and inactivates plasminogen activator inhibitor type 1
    • Urano T, Ihara H, Umemura K, et al. The profibrinolytic enzyme subtilisin NAT purified from Bacillus subtilis Cleaves and inactivates plasminogen activator inhibitor type 1. J Biol Chem. 2001;276(27): 24690-24696.
    • (2001) J Biol Chem , vol.276 , Issue.27 , pp. 24690-24696
    • Urano, T.1    Ihara, H.2    Umemura, K.3
  • 116
    • 33744742897 scopus 로고    scopus 로고
    • Posterior vitreous detachment induced by nattokinase (subtilisin NAT): A novel enzyme for pharmacologic vitreolysis
    • Takano A, Hirata A, Ogasawara K, et al. Posterior vitreous detachment induced by nattokinase (subtilisin NAT): a novel enzyme for pharmacologic vitreolysis. Invest Ophthalmol Vis Sci. 2006;47(5):2075-2079.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , Issue.5 , pp. 2075-2079
    • Takano, A.1    Hirata, A.2    Ogasawara, K.3
  • 117
    • 0019850184 scopus 로고
    • Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane
    • Liotta LA, Goldfarb RH, Brundage R, Siegal GP, Terranova V, Garbisa S. Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane. Cancer Res. 1981;41(11 Pt 1):4629-4636.
    • (1981) Cancer Res , vol.41 , Issue.11 PART 1 , pp. 4629-4636
    • Liotta, L.A.1    Goldfarb, R.H.2    Brundage, R.3    Siegal, G.P.4    Terranova, V.5    Garbisa, S.6
  • 118
    • 13244259215 scopus 로고    scopus 로고
    • Effect of plasmin on laminin and fibronectin during plasmin-assisted vitrectomy
    • Uemura A, Nakamura M, Kachi S, et al. Effect of plasmin on laminin and fibronectin during plasmin-assisted vitrectomy. Arch Ophthalmol. 2005;123(2):209-213.
    • (2005) Arch Ophthalmol , vol.123 , Issue.2 , pp. 209-213
    • Uemura, A.1    Nakamura, M.2    Kachi, S.3
  • 119
    • 0036934986 scopus 로고    scopus 로고
    • Posterior vitreous detachment with plasmin in the isolated human eye
    • Li X, Shi X, Fan J. Posterior vitreous detachment with plasmin in the isolated human eye. Graefes Arch Clin Exp Ophthalmol. 2002;240(1): 56-62.
    • (2002) Graefes Arch Clin Exp Ophthalmol , vol.240 , Issue.1 , pp. 56-62
    • Li, X.1    Shi, X.2    Fan, J.3
  • 120
    • 26844475132 scopus 로고    scopus 로고
    • Intravitreal plasmin injection activates endogenous matrix metalloproteinase-2 in rabbit and human vitreous
    • Takano A, Hirata A, Inomata Y, et al. Intravitreal plasmin injection activates endogenous matrix metalloproteinase-2 in rabbit and human vitreous. Am J Ophthalmol. 2005;140(4):654-660.
    • (2005) Am J Ophthalmol , vol.140 , Issue.4 , pp. 654-660
    • Takano, A.1    Hirata, A.2    Inomata, Y.3
  • 121
    • 0030907299 scopus 로고    scopus 로고
    • Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of pro-MMP-2 activation
    • Baramova EN, Bajou K, Remacle A, et al. Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of pro-MMP-2 activation. FEBS Lett. 1997;405(2):157-162.
    • (1997) FEBS Lett , vol.405 , Issue.2 , pp. 157-162
    • Baramova, E.N.1    Bajou, K.2    Remacle, A.3
  • 122
    • 0023900470 scopus 로고
    • Fibronectin degradation products containing the cytoadhesive tetrapeptide stimulate human neutrophil degranulation
    • Wachtfogel YT, Abrams W, Kucich U, Weinbaum G, Schapira M, Colman RW. Fibronectin degradation products containing the cytoadhesive tetrapeptide stimulate human neutrophil degranulation. J Clin Invest. 1988;81(5):1310-1316.
    • (1988) J Clin Invest , vol.81 , Issue.5 , pp. 1310-1316
    • Wachtfogel, Y.T.1    Abrams, W.2    Kucich, U.3    Weinbaum, G.4    Schapira, M.5    Colman, R.W.6
  • 123
    • 0033499267 scopus 로고    scopus 로고
    • Posterior vitreous detachment induced by injection of plasmin and sulfur hexafluoride in the rabbit vitreous
    • Hikichi T, Yanagiya N, Kado M, Akiba J, Yoshida A. Posterior vitreous detachment induced by injection of plasmin and sulfur hexafluoride in the rabbit vitreous. Retina. 1999;19(1):55-58.
    • (1999) Retina , vol.19 , Issue.1 , pp. 55-58
    • Hikichi, T.1    Yanagiya, N.2    Kado, M.3    Akiba, J.4    Yoshida, A.5
  • 125
    • 0036149076 scopus 로고    scopus 로고
    • Vitreoretinal morphology of plasmin-treated human eyes
    • Gandorfer A, Priglinger S, Schebitz K, et al. Vitreoretinal morphology of plasmin-treated human eyes. Am J Ophthalmol. 2002;133(1): 156-159.
    • (2002) Am J Ophthalmol , vol.133 , Issue.1 , pp. 156-159
    • Gandorfer, A.1    Priglinger, S.2    Schebitz, K.3
  • 127
    • 35448931168 scopus 로고    scopus 로고
    • Pediatric traumatic macular hole: Results of autologous plasmin enzyme-assisted vitrectomy
    • Wu WC, Drenser KA, Trese MT, Williams GA, Capone A. Pediatric traumatic macular hole: results of autologous plasmin enzyme-assisted vitrectomy. Am J Ophthalmol. 2007;144(5):668-672.
    • (2007) Am J Ophthalmol , vol.144 , Issue.5 , pp. 668-672
    • Wu, W.C.1    Drenser, K.A.2    Trese, M.T.3    Williams, G.A.4    Capone, A.5
  • 128
    • 34250745337 scopus 로고    scopus 로고
    • Autologous plasmin-assisted vitrectomy for stage 5 retinopathy of prematurity: A preliminary trial
    • Tsukahara Y, Honda S, Imai H, et al. Autologous plasmin-assisted vitrectomy for stage 5 retinopathy of prematurity: a preliminary trial. Am J Ophthalmol. 2007;144(1):139-141.
    • (2007) Am J Ophthalmol , vol.144 , Issue.1 , pp. 139-141
    • Tsukahara, Y.1    Honda, S.2    Imai, H.3
  • 129
    • 43149102977 scopus 로고    scopus 로고
    • Plasmin enzymeassisted vitrectomy for primary and reoperated eyes with stage 5 retinopathy of prematurity
    • Wu W-C, Drenser KA, Lai M, Capone A, Trese MT. Plasmin enzymeassisted vitrectomy for primary and reoperated eyes with stage 5 retinopathy of prematurity. Retina. 2008;28(Suppl 3):S75-S80.
    • (2008) Retina , vol.28 , Issue.SUPPL. 3
    • Wu, W.-C.1    Drenser, K.A.2    Lai, M.3    Capone, A.4    Trese, M.T.5
  • 130
    • 37349073713 scopus 로고    scopus 로고
    • Plasmin enzyme-assisted vitreoretinal surgery in congenital X-linked retinoschisis: Surgical techniques based on a new classification system
    • Wu W-C, Drenser KA, Capone A, Williams GA, Trese MT. Plasmin enzyme-assisted vitreoretinal surgery in congenital X-linked retinoschisis: surgical techniques based on a new classification system. Retina. 2007;27(8):1079-1085.
    • (2007) Retina , vol.27 , Issue.8 , pp. 1079-1085
    • Wu, W.-C.1    Drenser, K.A.2    Capone, A.3    Williams, G.A.4    Trese, M.T.5
  • 131
    • 0033769548 scopus 로고    scopus 로고
    • A new approach to stage 3 macular holes
    • Trese MT, Williams GA, Hartzer MK. A new approach to stage 3 macular holes. Ophthalmology. 2000;107(8):1607-1611.
    • (2000) Ophthalmology , vol.107 , Issue.8 , pp. 1607-1611
    • Trese, M.T.1    Williams, G.A.2    Hartzer, M.K.3
  • 132
    • 33748668813 scopus 로고    scopus 로고
    • Autologous plasmin for pharmacologic vitreolysis prepared 1 hour before surgery
    • Rizzo S, Pellegrini G, Benocci F, Belting C, Baicchi U, Vispi M. Autologous plasmin for pharmacologic vitreolysis prepared 1 hour before surgery. Retina. 2006;26(7):792-796.
    • (2006) Retina , vol.26 , Issue.7 , pp. 792-796
    • Rizzo, S.1    Pellegrini, G.2    Benocci, F.3    Belting, C.4    Baicchi, U.5    Vispi, M.6
  • 134
    • 7044222855 scopus 로고    scopus 로고
    • Intrasurgical plasmin enzyme in diabetic macular edema
    • Azzolini C, D'Angelo A, Maestranzi G, et al. Intrasurgical plasmin enzyme in diabetic macular edema. Am J Ophthalmol. 2004;138(4):560-566.
    • (2004) Am J Ophthalmol , vol.138 , Issue.4 , pp. 560-566
    • Azzolini, C.1    D'Angelo, A.2    Maestranzi, G.3
  • 136
    • 37349126621 scopus 로고    scopus 로고
    • Plasmin-assisted vitrectomy for management of proliferative membrane in proliferative diabetic retinopathy: A pilot study
    • Hirata A, Takano A, Inomata Y, Yonemura N, Sagara N, Tanihara H. Plasmin-assisted vitrectomy for management of proliferative membrane in proliferative diabetic retinopathy: a pilot study. Retina. 2007;27(8):1074-1078.
    • (2007) Retina , vol.27 , Issue.8 , pp. 1074-1078
    • Hirata, A.1    Takano, A.2    Inomata, Y.3    Yonemura, N.4    Sagara, N.5    Tanihara, H.6
  • 137
    • 79952587815 scopus 로고    scopus 로고
    • Intravitreal plasmin without vitrectomy for macular edema secondary to branch retinal vein occlusion
    • Udaondo P, Diaz-Llopis M, Garcia-Delpech S, Salom D, Romero FJ. Intravitreal plasmin without vitrectomy for macular edema secondary to branch retinal vein occlusion. Arch Ophthalmol. 2011;129(3): 283-287.
    • (2011) Arch Ophthalmol , vol.129 , Issue.3 , pp. 283-287
    • Udaondo, P.1    Diaz-Llopis, M.2    Garcia-Delpech, S.3    Salom, D.4    Romero, F.J.5
  • 138
    • 0034103574 scopus 로고    scopus 로고
    • Tissue plasminogen activator in the treatment of vitreoretinal diseases
    • Kamei M, Estafanous M, Lewis H. Tissue plasminogen activator in the treatment of vitreoretinal diseases. Semin Ophthalmol. 2000;15(1): 44-50.
    • (2000) Semin Ophthalmol , vol.15 , Issue.1 , pp. 44-50
    • Kamei, M.1    Estafanous, M.2    Lewis, H.3
  • 139
    • 0034042322 scopus 로고    scopus 로고
    • Treatment of recent onset central retinal vein occlusion with intravitreal tissue plasminogen activator: A pilot study
    • Glacet-Bernard A, Kuhn D, Vine AK, Oubraham H, Coscas G, Soubrane G. Treatment of recent onset central retinal vein occlusion with intravitreal tissue plasminogen activator: a pilot study. Br J Ophthalmol. 2000;84(6):609-613.
    • (2000) Br J Ophthalmol , vol.84 , Issue.6 , pp. 609-613
    • Glacet-Bernard, A.1    Kuhn, D.2    Vine, A.K.3    Oubraham, H.4    Coscas, G.5    Soubrane, G.6
  • 140
    • 0033506960 scopus 로고    scopus 로고
    • TPA-assisted vitrectomy for proliferative diabetic retinopathy: Results of a doublemasked, multicenter trial
    • Le Mer Y, Korobelnik JF, Morel C, Ullern M, Berrod JP. TPA-assisted vitrectomy for proliferative diabetic retinopathy: results of a doublemasked, multicenter trial. Retina. 1999;19(5):378-382.
    • (1999) Retina , vol.19 , Issue.5 , pp. 378-382
    • le Mer, Y.1    Korobelnik, J.F.2    Morel, C.3    Ullern, M.4    Berrod, J.P.5
  • 142
    • 0033968761 scopus 로고    scopus 로고
    • Induction of posterior vitreous detachment in rabbits by intravitreal injection of tissue plasminogen activator following cryopexy
    • Hesse L, Nebeling B, Schroeder B, Heller G, Kroll P. Induction of posterior vitreous detachment in rabbits by intravitreal injection of tissue plasminogen activator following cryopexy. Exp Eye Res. 2000;70(1):31-39.
    • (2000) Exp Eye Res , vol.70 , Issue.1 , pp. 31-39
    • Hesse, L.1    Nebeling, B.2    Schroeder, B.3    Heller, G.4    Kroll, P.5
  • 143
    • 0034129529 scopus 로고    scopus 로고
    • The efficacy of plasminogen-urokinase combination in inducing posterior vitreous detachment
    • Unal M, Peyman GA. The efficacy of plasminogen-urokinase combination in inducing posterior vitreous detachment. Retina. 2000;20(1): 69-75.
    • (2000) Retina , vol.20 , Issue.1 , pp. 69-75
    • Unal, M.1    Peyman, G.A.2
  • 144
    • 1942509681 scopus 로고    scopus 로고
    • The role of recombinant lysine-plasminogen and recombinant urokinase and sulfur hexafluoride combination in inducing posterior vitreous detachment
    • Men G, Peyman GA, Genaidy M, et al. The role of recombinant lysine-plasminogen and recombinant urokinase and sulfur hexafluoride combination in inducing posterior vitreous detachment. Retina. 2004; 24(2):199-209.
    • (2004) Retina , vol.24 , Issue.2 , pp. 199-209
    • Men, G.1    Peyman, G.A.2    Genaidy, M.3
  • 145
    • 0033946073 scopus 로고    scopus 로고
    • TPA-assisted vitrectomy for proliferative diabetic retinopathy
    • Hesse L, Kroll P. TPA-assisted vitrectomy for proliferative diabetic retinopathy. Retina. 2000;20(3):317-318.
    • (2000) Retina , vol.20 , Issue.3 , pp. 317-318
    • Hesse, L.1    Kroll, P.2
  • 146
    • 37349100816 scopus 로고    scopus 로고
    • Role of posterior vitreous detachment induced by intravitreal tissue plasminogen activator in macular edema with central retinal vein occlusion
    • Murakami T, Takagi H, Ohashi H, et al. Role of posterior vitreous detachment induced by intravitreal tissue plasminogen activator in macular edema with central retinal vein occlusion. Retina. 2007;27(8): 1031-1037.
    • (2007) Retina , vol.27 , Issue.8 , pp. 1031-1037
    • Murakami, T.1    Takagi, H.2    Ohashi, H.3
  • 147
    • 0141673321 scopus 로고    scopus 로고
    • Recombinant human microplasmin: Production and potential therapeutic properties
    • Nagai N, Demarsin E, Van Hoef B, et al. Recombinant human microplasmin: production and potential therapeutic properties. J Thromb Haemost. 2003;1(2):307-313.
    • (2003) J Thromb Haemost , vol.1 , Issue.2 , pp. 307-313
    • Nagai, N.1    Demarsin, E.2    van Hoef, B.3
  • 148
    • 0942298146 scopus 로고    scopus 로고
    • Posterior vitreous detachment induced by microplasmin
    • Gandorfer A, Rohleder M, Sethi C, et al. Posterior vitreous detachment induced by microplasmin. Invest Ophthalmol Vis Sci. 2004;45(2): 641-647.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.2 , pp. 641-647
    • Gandorfer, A.1    Rohleder, M.2    Sethi, C.3
  • 149
    • 27244451971 scopus 로고    scopus 로고
    • Safety of in vivo pharmacologic vitreolysis with recombinant microplasmin in rabbit eyes
    • Sakuma T, Tanaka M, Mizota A, Inoue J, Pakola S. Safety of in vivo pharmacologic vitreolysis with recombinant microplasmin in rabbit eyes. Invest Ophthalmol Vis Sci. 2005;46(9):3295-3299.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.9 , pp. 3295-3299
    • Sakuma, T.1    Tanaka, M.2    Mizota, A.3    Inoue, J.4    Pakola, S.5
  • 150
    • 39449103901 scopus 로고    scopus 로고
    • Enzymatic vitreolysis with recombinant microplasminogen and tissue plasminogen activator
    • Chen W, Huang X, Ma XW, Mo W, Wang WJ, Song HY. Enzymatic vitreolysis with recombinant microplasminogen and tissue plasminogen activator. Eye (Lond). 2008;22(2):300-307.
    • (2008) Eye (Lond) , vol.22 , Issue.2 , pp. 300-307
    • Chen, W.1    Huang, X.2    Ma, X.W.3    Mo, W.4    Wang, W.J.5    Song, H.Y.6
  • 152
    • 67649487961 scopus 로고    scopus 로고
    • Microplasmin intravitreal administration in patients with vitreomacular traction scheduled for vitrectomy: The MIVI I trial
    • de Smet MD, Gandorfer A, Stalmans P, et al. Microplasmin intravitreal administration in patients with vitreomacular traction scheduled for vitrectomy: the MIVI I trial. Ophthalmology. 2009;116(7):1349-1355, 1355. e1341-e1342.
    • (2009) Ophthalmology , vol.116 , Issue.7
    • de Smet, M.D.1    Gandorfer, A.2    Stalmans, P.3
  • 153
    • 77954734096 scopus 로고    scopus 로고
    • Intravitreal injection of microplasmin for treatment of vitreomacular adhesion: Results of a prospective, randomized, sham-controlled phase II trial (the MIVI-IIT trial)
    • Stalmans P, Delaey C, de Smet MD, van Dijkman E, Pakola S. Intravitreal injection of microplasmin for treatment of vitreomacular adhesion: results of a prospective, randomized, sham-controlled phase II trial (the MIVI-IIT trial). Retina. 2010;30(7):1122-1127.
    • (2010) Retina , vol.30 , Issue.7 , pp. 1122-1127
    • Stalmans, P.1    Delaey, C.2    de Smet, M.D.3    van Dijkman, E.4    Pakola, S.5
  • 154
    • 80051710419 scopus 로고    scopus 로고
    • A single injection of ocriplasmin for the treatment of symptomatic vitreomacular adhesion (sVMA): Results of the Phase III MIVI-TRUST Program [abstract]
    • Dugel PU, Group M-TS. A single injection of ocriplasmin for the treatment of symptomatic vitreomacular adhesion (sVMA): results of the Phase III MIVI-TRUST Program [abstract]. Invest Ophthalmol Vis Sci (Suppl). 2011;52:6628.
    • (2011) Invest Ophthalmol Vis Sci (Suppl) , vol.52 , pp. 6628
    • Dugel, P.U.1    Group, M.-T.S.2
  • 155
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell. 1992;69(1):11-25.
    • (1992) Cell , vol.69 , Issue.1 , pp. 11-25
    • Hynes, R.O.1
  • 156
    • 0023839836 scopus 로고
    • Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides
    • Gehlsen KR, Argraves WS, Pierschbacher MD, Ruoslahti E. Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides. J Cell Biol. 1988;106(3):925-930.
    • (1988) J Cell Biol , vol.106 , Issue.3 , pp. 925-930
    • Gehlsen, K.R.1    Argraves, W.S.2    Pierschbacher, M.D.3    Ruoslahti, E.4
  • 157
    • 0028020438 scopus 로고
    • Immunolocalization of integrins in the human retina
    • Brem RB, Robbins SG, Wilson DJ, et al. Immunolocalization of integrins in the human retina. Invest Ophthalmol Vis Sci. 1994;35(9): 3466-3474.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , Issue.9 , pp. 3466-3474
    • Brem, R.B.1    Robbins, S.G.2    Wilson, D.J.3
  • 158
    • 0038309763 scopus 로고    scopus 로고
    • RGD peptide-assisted vitrectomy to facilitate induction of a posterior vitreous detachment: A new principle in pharmacological vitreolysis
    • Oliveira LB, Meyer CH, Kumar J, et al. RGD peptide-assisted vitrectomy to facilitate induction of a posterior vitreous detachment: a new principle in pharmacological vitreolysis. Curr Eye Res. 2002; 25(6):333-340.
    • (2002) Curr Eye Res , vol.25 , Issue.6 , pp. 333-340
    • Oliveira, L.B.1    Meyer, C.H.2    Kumar, J.3
  • 159
    • 80051716220 scopus 로고    scopus 로고
    • Determine the safety and efficacy of Vitreosolve® administered intravitreally to induce a complete posterior vitreous detachment (PVD) in non proliferative diabetic retinopathy human subjects
    • Karageozian HL. Determine the safety and efficacy of Vitreosolve® administered intravitreally to induce a complete posterior vitreous detachment (PVD) in non proliferative diabetic retinopathy human subjects Invest Ophthalmol Vis Sci (Suppl). 2005;46:5453.
    • (2005) Invest Ophthalmol Vis Sci (Suppl) , vol.46 , pp. 5453
    • Karageozian, H.L.1
  • 160
    • 0023303232 scopus 로고
    • Chemical analysis of bovine and porcine vitreous humors: Correlation of normal values with serum chemical values and changes with time and temperature
    • McLaughlin PS, McLaughlin BG. Chemical analysis of bovine and porcine vitreous humors: correlation of normal values with serum chemical values and changes with time and temperature. Am J Vet Res. 1987;48(3):467-473.
    • (1987) Am J Vet Res , vol.48 , Issue.3 , pp. 467-473
    • McLaughlin, P.S.1    McLaughlin, B.G.2
  • 161
    • 23044495020 scopus 로고    scopus 로고
    • Pharmacologic vitreolysis combining the two enzymes plasmin and hyaluronidase
    • author reply 674-675
    • Gandorfer A, Kampik A. Pharmacologic vitreolysis combining the two enzymes plasmin and hyaluronidase. Retina. 2005;25(5):674; author reply 674-675.
    • (2005) Retina , vol.25 , Issue.5 , pp. 674
    • Gandorfer, A.1    Kampik, A.2
  • 162
    • 63249123345 scopus 로고    scopus 로고
    • Pharmacologic vitreolysis with plasmin and hyaluronidase in diabetic rats
    • Zhi-Liang W, Wo-Dong S, Min L, Xiao-Ping B, Jin J. Pharmacologic vitreolysis with plasmin and hyaluronidase in diabetic rats. Retina. 2009;29(2):269-274.
    • (2009) Retina , vol.29 , Issue.2 , pp. 269-274
    • Zhi-Liang, W.1    Wo-Dong, S.2    Min, L.3    Xiao-Ping, B.4    Jin, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.