Safety and efficacy of dispase and plasmin in pharmacologic vitreolysis

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 9, 2004, Pages 3286-3290

  Wang, Fenghua ^a   Wang, Zhiliang ^a   Sun, Xiaodong ^a   Wang, Fang ^a   Xu, Xun ^a   Zhang, Xi ^a,b  

^a SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

^b NONE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DISPASE; PLASMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ECHOOCULOGRAPHY; ELECTRORETINOGRAPHY; EYE INFLAMMATION; HISTOPATHOLOGY; MALE; NONHUMAN; OPHTHALMOSCOPY; PRIORITY JOURNAL; RABBIT; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; VITREOUS BODY; VITREOUS BODY DETACHMENT;

ANIMALS; CATARACT; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRORETINOGRAPHY; ENDOPEPTIDASES; ENDOPHTHALMITIS; FUNDUS OCULI; INJECTIONS; MICROSCOPY, ELECTRON; MICROSCOPY, ELECTRON, SCANNING; PLASMIN; RABBITS; RANDOM ALLOCATION; RETINAL HEMORRHAGE; VITREOUS BODY;

EID: 4344580726     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-0026     Document Type: Article

References (22)

1. Sebag J. Classifying posterior vitreous detachment: a new way to look at the invisible. Br J Ophthalmol. 1997;81:521.
2. Kakehashi A, Kado M, Akiba J, et al. Variations of posterior vitreous detachment. Br J Ophthalmol. 1997;81:527-532.
3. Hesse L. Using enzymes in the posterior eye segment: current status and future possibilities. Ophthalmologe. 2001;98:1176-1180.
4. Robert B. Anticipation for enzymatic vitreolysis (editorial). Br J Ophthalmol. 2001;85:1-2.
5. Sebag J. Pharmacologic vitreolysis. Retina. 1998;18:1-3.
6. Sebag J. Is pharmacologic vitreolysis brewing? Retina. 2002;22: 1-3.
7. Verstraeten TC, Chapman C, Hartzer M, et al. Pharmacologic induction of posterior vitreous detachment in the rabbit. Arch Ophthalmol. 1993;111:849-854.
8. Tezel TH, Del Priore LV, Kaplan HJ. Posterior vitreous detachment with dispase. Retina. 1998;18:7-15.
9. Harooni M, McMillan T, Refojo M. Efficacy and safety of enzymatic posterior vitreous detachment by intravitreal injection of hyaluronidase. Retina. 1998;18:16-22.
10. Unal M, Peyman GA. The efficacy of plasminogen-urokinase combination in inducing posterior vitreous detachment. Retina. 2000; 20:69-75.
11. Fenghua W, Xi Z, Xiaodong S. Efficacy and safety of dispase in inducing posterior vitreous detachment of rabbit eyes [in Chinese]. Chin Ophthalmic Res. 2003;21:121-125.
12. Oliveira LB, Tatebayashi M, Mahmoud TH, et al. Dispase facilitates posterior vitreous detachment during vitrectomy in young pigs. Retina. 2001;21:324-331.
13. Williams JG, Trese MT, Williams GA, et al. Autologous plasmin enzyme in the surgical management of diabetic retinopathy. Ophthalmology. 2001;108:1902-1905.
14. Trese MT, Williams GA, Hartzer MK. A new approach to stage 3 macular holes. Ophthalmology. 2000;107:1607-1611.
15. Liotta LA, Goldfarb RH, Brundage R, et al. Effect of plasminogen activator, plasmin, and thrombin on glycoprotein and collagenous components of basement membrane. Cancer Res. 1981;41:4629-4636.
16. Li X, Shi X, Fan J. Posterior vitreous detachment with plasmin in the isolated human eye. Graefes Arch Clin Exp Ophthalmol. 2002; 240:56-62.
17. Pearson PA, Jaffe GJ, Martin DF, et al. Evaluation of a delivery system providing long-term release of cyclosporine. Arch Ophthalmol. 1996;114:311-317.
18. Gandorfer A, Putz E, Welge-Lussen U, et al. Ultrastructure of the vitreoretinal interface following plasmin assisted vitrectomy. Br J Ophthalmol. 2001;85:6-10.
19. Gandorfer A, Priglinger S, Schebitz K, et al. Vitreoretinal morphology of plasmin-treated human eyes. Am J Ophthalmol. 2002;133: 156-159.
20. Gandorfer A, Rohleder M, Sethi C, et al. Posterior vitreous detachment induced by microplasmin. Invest Ophthalmol Vis Sci. 2004; 45:641-647.
21. Jorge R, Oyamaguchi EK, Cardillo JA, et al. Intravitreal injection of dispase causes retinal hemorrhages in rabbit and human eyes. Curr Eye Res. 2003;26:107-112.
22. Frenzel EM, Neely KA, Walsh AW, et al. A new model of proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 1998;39:2157-2164.