Biochemical characterization of the chondroitinase ABC I active site

Biochemical Journal

Volumn 390, Issue 2, 2005, Pages 395-405

  Prabhakar, Vikas ^a   Raman, Rahul ^a   Capila, Ishan ^a   Bosques, Carlos J ^a   Pojasek, Kevin ^a   Sasisekharan, Ram ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Active site; Chondroitin sulphate (CS); Chondroitinase ABC (cABC); Dermatan sulphate; Mode of action; Mutagenesis

Indexed keywords

BIOCHEMISTRY; CATALYSIS; CHARACTERIZATION; CLONING; HYDROGEN BONDS; MUTAGENESIS; ORGANIC ACIDS;

ACTIVE SITE; CHONDROITIN SULPHATE (CS); CHONDROITINASE ABC (CABC); DERMATAN SULPHATE;

ENZYMES;

ARGININE; CHONDROITIN ABC LYASE; CHONDROITIN SULFATE; CHONDROITINASE ABC 1; DERMATAN SULFATE; GALACTOSAMINOGLYCAN; GLUTAMIC ACID; HISTIDINE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS; SWINE;

ANIMALS; BINDING SITES; CARBOHYDRATE CONFORMATION; CATALYSIS; CHONDROITIN ABC LYASE; GLYCOSAMINOGLYCANS; KINETICS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTEUS VULGARIS; RECOMBINANT PROTEINS; SHARKS; SUBSTRATE SPECIFICITY; SWINE;

ESCHERICHIA COLI; PROTEUS VULGARIS;

EID: 25144514918     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050532     Document Type: Article

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