The Profibrinolytic Enzyme Subtilisin NAT Purified from Bacillus subtilis Cleaves and Inactivates Plasminogen Activator Inhibitor Type 1

Journal of Biological Chemistry

Volumn 276, Issue 27, 2001, Pages 24690-24696

  Urano, Tetsumei ^a   Ihara, Hayato ^a   Umemura, Kazuo ^a   Suzuki, Yasuhiro ^a   Oike, Masaki ^b   Akita, Sumio ^b   Tsukamoto, Yoshinori ^b   Suzuki, Isao ^c   Takada, Akikazu ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Mitsukan Group Corporation   (Japan)

^c PREFECTURAL UNIVERSITY OF KUMAMOTO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; DESORPTION; ENZYMES; IONIZATION; MOLECULAR WEIGHT;

CLEAVAGE; FIBRINOLYSIS;

BIOCHEMISTRY;

PLASMINOGEN; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; SERINE PROTEINASE; SUBTILISIN; SUBTILISIN NAT; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; FIBRIN; FIBRINOGEN; NATTOKINASE;

AMINO ACID SEQUENCE; ARTICLE; BACILLUS SUBTILIS; DOSE RESPONSE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PURIFICATION; FIBRIN CLOT; FIBRINOLYSIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; SEQUENCE ANALYSIS; DRUG EFFECT; ENZYMOLOGY; HUMAN; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; PEPTIDE MAPPING; POLYACRYLAMIDE GEL ELECTROPHORESIS;

BACILLUS SUBTILIS; PROKARYOTA; VERTEBRATA; NIA;

BACILLUS SUBTILIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBRIN; FIBRINOGEN; FIBRINOLYSIS; HUMANS; MOLECULAR WEIGHT; PEPTIDE MAPPING; PLASMINOGEN ACTIVATOR INHIBITOR 1; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUBTILISINS;

EID: 0035816636     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101751200     Document Type: Article

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