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Volumn 122, Issue 2, 2011, Pages 235-252

Biological qualification of biomarkers of chemical-induced renal toxicity in two strains of male rat

(13)  Harpur, Ernie a,m   Ennulat, Daniela b   Hoffman, David c   Betton, Graham d   Gautier, Jean Charles c   Riefke, Bjoern e   Bounous, Denise f   Schuster, Kerstin g,n   Beushausen, Sven h,o   Guffroy, Magali i   Shaw, Martin j   Lock, Edward k   Pettit, Syril l  

c SANOFI   (France)

Author keywords

GST; Albumin; Biomarker performance; Cisplatin; Clusterin; Collecting duct; Degeneration; Gentamicin; N phenylanthranilic acid; NAG; Necrosis; Protein; Proximal tubule; Receiver operating characteristic; Regeneration; RPA 1; RPN; Urinary biomarkers

Indexed keywords

BIOLOGICAL MARKER; CISPLATIN; CLUSTERIN; CREATININE; EFENAMIC ACID; GENTAMICIN; GLUTATHIONE TRANSFERASE ALPHA; GLUTATHIONE TRANSFERASE MU; N ACETYL BETA GLUCOSAMINIDASE; RENAL PAPILLARY ANTIGEN 1; UNCLASSIFIED DRUG;

EID: 80051703759     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr112     Document Type: Article
Times cited : (123)

References (59)
  • 2
    • 2642647117 scopus 로고    scopus 로고
    • Renal papillary necrosis-40 years on
    • Bach, P. H., and Thanh, N. K. (1998). Renal papillary necrosis-40 years on. Toxicol. Pathol. 26, 73-91.
    • (1998) Toxicol. Pathol. , vol.26 , pp. 73-91
    • Bach, P.H.1    Thanh, N.K.2
  • 3
    • 0018573217 scopus 로고
    • Radioimmunoassay measurement of urinary ligandin excretion in nephrotoxin-treated rats
    • Bass, N. M., Kirsch, R. E., Tuff, S. A., Campbell, J. A., and Saunders, J. S. (1979). Radioimmunoassay measurement of urinary ligandin excretion in nephrotoxin-treated rats. Clin. Sci. (Lond.) 56, 419-426.
    • (1979) Clin. Sci. (Lond.) , vol.56 , pp. 419-426
    • Bass, N.M.1    Kirsch, R.E.2    Tuff, S.A.3    Campbell, J.A.4    Saunders, J.S.5
  • 4
    • 0027344154 scopus 로고
    • Glutathione S-transferases: biomedical applications
    • Beckett, G. J., and Hayes, J. D. (1993). Glutathione S-transferases: biomedical applications. Adv. Clin. Chem. 30, 281-380.
    • (1993) Adv. Clin. Chem. , vol.30 , pp. 281-380
    • Beckett, G.J.1    Hayes, J.D.2
  • 5
    • 36649002717 scopus 로고    scopus 로고
    • Protein biomarkers of nephrotoxicity; a review and findings with cyclosporin A, a signal transduction kinase inhibitor and N-phenylanthranilic acid
    • Betton, G. R., Kenne, K., Somers, R., and Marr, A. (2005). Protein biomarkers of nephrotoxicity; a review and findings with cyclosporin A, a signal transduction kinase inhibitor and N-phenylanthranilic acid. Cancer Biomark. 1, 59-67.
    • (2005) Cancer Biomark , vol.1 , pp. 59-67
    • Betton, G.R.1    Kenne, K.2    Somers, R.3    Marr, A.4
  • 7
    • 0034033688 scopus 로고    scopus 로고
    • Urinary excretion of glutathione S transferases alpha and pi in patients with proteinuria: reflection of the site of tubular injury
    • Branten, A. J., Mulder, T. P., Peters, W. H., Assmann, K. J., and Wetzels, J. F. (2000). Urinary excretion of glutathione S transferases alpha and pi in patients with proteinuria: reflection of the site of tubular injury. Nephron 85, 120-126.
    • (2000) Nephron , vol.85 , pp. 120-126
    • Branten, A.J.1    Mulder, T.P.2    Peters, W.H.3    Assmann, K.J.4    Wetzels, J.F.5
  • 9
    • 0025801691 scopus 로고
    • Immunohistologic localization of alpha, mu, and pi class glutathione S-transferases in human tissues
    • Campbell, J. A., Corrigall, A. V., Guy, A., and Kirsch, R. E. (1991). Immunohistologic localization of alpha, mu, and pi class glutathione S-transferases in human tissues. Cancer 67, 1608-1613.
    • (1991) Cancer , vol.67 , pp. 1608-1613
    • Campbell, J.A.1    Corrigall, A.V.2    Guy, A.3    Kirsch, R.E.4
  • 10
    • 33645676331 scopus 로고    scopus 로고
    • Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma
    • Chana, R. S., and Brunskill, N. J. (2006). Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma. Am. J. Nephrol. 26, 67-74.
    • (2006) Am. J. Nephrol. , vol.26 , pp. 67-74
    • Chana, R.S.1    Brunskill, N.J.2
  • 11
    • 42149105187 scopus 로고    scopus 로고
    • Biomarkers for the diagnosis and risk stratification of acute kidney injury: a systematic review
    • Coca, S. G., Yalavarthy, R., Concato, J., and Parikh, C. R. (2008). Biomarkers for the diagnosis and risk stratification of acute kidney injury: a systematic review. Kidney Int. 73, 1008-1016.
    • (2008) Kidney Int , vol.73 , pp. 1008-1016
    • Coca, S.G.1    Yalavarthy, R.2    Concato, J.3    Parikh, C.R.4
  • 15
    • 0037338437 scopus 로고    scopus 로고
    • Pathophysiology of proteinuria
    • D'Amico, G., and Bazzi, C. (2003). Pathophysiology of proteinuria. Kidney Int. 63, 809-825.
    • (2003) Kidney Int , vol.63 , pp. 809-825
    • D'Amico, G.1    Bazzi, C.2
  • 16
    • 0023710206 scopus 로고
    • Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach
    • DeLong, E. R., DeLong, D. M., and Clarke-Pearson, D. L. (1988). Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44, 837-845.
    • (1988) Biometrics , vol.44 , pp. 837-845
    • DeLong, E.R.1    DeLong, D.M.2    Clarke-Pearson, D.L.3
  • 18
    • 0031896803 scopus 로고    scopus 로고
    • Gamma-glutamyltransferase is a reliable marker for tubular effects of contrast media
    • Donadio, C., Tramonti, G., Lucchesi, A., Giordani, R., Lucchetti, A., and Bianchi, C. (1998). Gamma-glutamyltransferase is a reliable marker for tubular effects of contrast media. Ren. Fail. 20, 319-324.
    • (1998) Ren. Fail. , vol.20 , pp. 319-324
    • Donadio, C.1    Tramonti, G.2    Lucchesi, A.3    Giordani, R.4    Lucchetti, A.5    Bianchi, C.6
  • 23
    • 0034843154 scopus 로고    scopus 로고
    • Glomerular permselectivity factors are not responsible for the increase in fractional clearance of albumin in rat glomerulonephritis
    • Greive, K. A., Nikolic-Paterson, D. J., Guimaraes, M. A., Nikolovski, J., Pratt, L. M., Mu, W., Atkins, R. C., and Comper, W. D. (2001). Glomerular permselectivity factors are not responsible for the increase in fractional clearance of albumin in rat glomerulonephritis. Am. J. Pathol. 159, 1159-1170.
    • (2001) Am. J. Pathol. , vol.159 , pp. 1159-1170
    • Greive, K.A.1    Nikolic-Paterson, D.J.2    Guimaraes, M.A.3    Nikolovski, J.4    Pratt, L.M.5    Mu, W.6    Atkins, R.C.7    Comper, W.D.8
  • 24
    • 10244240498 scopus 로고    scopus 로고
    • Biologic markers for the early detection of acute kidney injury
    • Han, W. K., and Bonventre, J. V. (2004). Biologic markers for the early detection of acute kidney injury. Curr.Opin. Crit. Care 10, 476-482.
    • (2004) Curr. Opin. Crit. Care , vol.10 , pp. 476-482
    • Han, W.K.1    Bonventre, J.V.2
  • 25
    • 0020083498 scopus 로고
    • The meaning and use of the area under a receiver operating characteristic (ROC) curve
    • Hanley, J. A., and McNeil, B. J. (1982). The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 143, 29-36.
    • (1982) Radiology , vol.143 , pp. 29-36
    • Hanley, J.A.1    McNeil, B.J.2
  • 26
    • 0024333641 scopus 로고
    • Distribution of glutathione S-transferase isoenzymes in human kidney: basis for possible markers of renal injury
    • Harrison, D. J., Kharbanda, R., Cunningham, D. S., McLellan, L. I., and Hayes, J. D. (1989). Distribution of glutathione S-transferase isoenzymes in human kidney: basis for possible markers of renal injury. J. Clin. Pathol. 42, 624-628.
    • (1989) J. Clin. Pathol. , vol.42 , pp. 624-628
    • Harrison, D.J.1    Kharbanda, R.2    Cunningham, D.S.3    McLellan, L.I.4    Hayes, J.D.5
  • 28
    • 18744411216 scopus 로고    scopus 로고
    • Urinary clusterin levels in the rat correlate with the severity of tubular damage and may help to differentiate between glomerular and tubular injuries
    • Hidaka, S., Kranzlin, B., Gretz, N., and Witzgall, R. (2002). Urinary clusterin levels in the rat correlate with the severity of tubular damage and may help to differentiate between glomerular and tubular injuries. Cell Tissue Res. 310, 289-296.
    • (2002) Cell Tissue Res , vol.310 , pp. 289-296
    • Hidaka, S.1    Kranzlin, B.2    Gretz, N.3    Witzgall, R.4
  • 29
    • 0032806166 scopus 로고    scopus 로고
    • Urinary antigens as markers of papillary toxicity II: application of monoclonal antibodies for the determination of papillary antigens in rat urine
    • Hildebrand, H., Rinke, M., Schluter, G., Bomhard, E., and Falkenberg, F. W. (1999). Urinary antigens as markers of papillary toxicity. II: application of monoclonal antibodies for the determination of papillary antigens in rat urine. Arch. Toxicol. 73, 233-245.
    • (1999) Arch. Toxicol. , vol.73 , pp. 233-245
    • Hildebrand, H.1    Rinke, M.2    Schluter, G.3    Bomhard, E.4    Falkenberg, F.W.5
  • 30
    • 33645762226 scopus 로고    scopus 로고
    • A sharper Bonferroni procedure for multiple significance testing
    • Hochberg, Y. (1998). A sharper Bonferroni procedure for multiple significance testing. Biometrika 75, 800-803.
    • (1998) Biometrika , vol.75 , pp. 800-803
    • Hochberg, Y.1
  • 31
    • 33947369104 scopus 로고    scopus 로고
    • Molecular pathological evaluation of clusterin in a rat model of unilateral ureteral obstruction as a possible biomarker of nephrotoxicity
    • Ishii, A., Sakai, Y., and Nakamura, A. (2007). Molecular pathological evaluation of clusterin in a rat model of unilateral ureteral obstruction as a possible biomarker of nephrotoxicity. Toxicol. Pathol. 35, 376-382.
    • (2007) Toxicol. Pathol. , vol.35 , pp. 376-382
    • Ishii, A.1    Sakai, Y.2    Nakamura, A.3
  • 32
    • 0029416888 scopus 로고
    • Strain as a determinant factor in the differential responsiveness of rats to chemicals
    • Kacew, S., Ruben, Z., and McConnell, R. F. (1995). Strain as a determinant factor in the differential responsiveness of rats to chemicals. Toxicol. Pathol. 23, 701-714.
    • (1995) Toxicol. Pathol. , vol.23 , pp. 701-714
    • Kacew, S.1    Ruben, Z.2    McConnell, R.F.3
  • 33
    • 0031777738 scopus 로고    scopus 로고
    • Role of the renal cysteine conjugate beta-lyase pathway in inhaled compound A nephrotoxicity in rats
    • Kharasch, E. D., Hoffman, G. M., Thorning, D., Hankins, D. C., and Kilty, C. G. (1998). Role of the renal cysteine conjugate beta-lyase pathway in inhaled compound A nephrotoxicity in rats. Anesthesiology 88, 1624-1633.
    • (1998) Anesthesiology , vol.88 , pp. 1624-1633
    • Kharasch, E.D.1    Hoffman, G.M.2    Thorning, D.3    Hankins, D.C.4    Kilty, C.G.5
  • 34
    • 33645121719 scopus 로고    scopus 로고
    • Gene expression profiling of nephrotoxicity from the sevoflurane degradation product fluoromethyl-2 2-difluoro-1-(trifluoromethyl)vinyl ether ("compound A") in rats
    • Kharasch, E. D., Schroeder, J. L., Bammler, T., Beyer, R., and Srinouanprachanh, S. (2006). Gene expression profiling of nephrotoxicity from the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether ("compound A") in rats. Toxicol. Sci. 90, 419-431.
    • (2006) Toxicol. Sci. , vol.90 , pp. 419-431
    • Kharasch, E.D.1    Schroeder, J.L.2    Bammler, T.3    Beyer, R.4    Srinouanprachanh, S.5
  • 37
    • 0015576741 scopus 로고
    • Strain differences in metabolism and susceptibility to the nephrotoxic effects of methoxyflurance in rats
    • Mazze, R., Cousins, M. J., and Kosek, J. C. (1973). Strain differences in metabolism and susceptibility to the nephrotoxic effects of methoxyflurance in rats. J. Pharm. Exp. Ther. 184, 481-488.
    • (1973) J. Pharm. Exp. Ther. , vol.184 , pp. 481-488
    • Mazze, R.1    Cousins, M.J.2    Kosek, J.C.3
  • 38
    • 0020622896 scopus 로고
    • Acetaminophen nephrotoxicity in the rat I. Strain differences in nephrotoxicity and metabolism
    • Newton, J. F., Yoshimoto, M., Bernstein, J., Rush, G. F., and Hook, J. B. (1983). Acetaminophen nephrotoxicity in the rat. I. Strain differences in nephrotoxicity and metabolism. Toxicol. Appl. Pharmacol. 69, 291-306.
    • (1983) Toxicol. Appl. Pharmacol. , vol.69 , pp. 291-306
    • Newton, J.F.1    Yoshimoto, M.2    Bernstein, J.3    Rush, G.F.4    Hook, J.B.5
  • 39
    • 77952228263 scopus 로고    scopus 로고
    • A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function
    • Ozer, J. S., Dieterle, F., Troth, S., Perentes, E., Cordier, A., Verdes, P., Staedtler, F., Mahl, A., Grenet, O., Roth, D. R., et al. (2010). A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function. Nat. Biotechnol. 28, 486-494.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 486-494
    • Ozer, J.S.1    Dieterle, F.2    Troth, S.3    Perentes, E.4    Cordier, A.5    Verdes, P.6    Staedtler, F.7    Mahl, A.8    Grenet, O.9    Roth, D.R.10
  • 40
    • 77954418915 scopus 로고    scopus 로고
    • Tubular proteinuria in acute kidney injury: a critical evaluation of current status and future promise
    • Parikh, C. R., Lu, J. C., Coca, S. G., and Devarajan, P. (2010). Tubular proteinuria in acute kidney injury: a critical evaluation of current status and future promise. Ann. Clin. Biochem. 47, 301-312.
    • (2010) Ann. Clin. Biochem. , vol.47 , pp. 301-312
    • Parikh, C.R.1    Lu, J.C.2    Coca, S.G.3    Devarajan, P.4
  • 43
    • 0029124742 scopus 로고
    • Clusterin: physiologic and pathophysiologic considerations
    • Rosenberg, M. E., and Silkensen, J. (1995). Clusterin: physiologic and pathophysiologic considerations. Int. J. Biochem. Cell Biol. 27, 633-645.
    • (1995) Int. J. Biochem. Cell Biol. , vol.27 , pp. 633-645
    • Rosenberg, M.E.1    Silkensen, J.2
  • 44
    • 0027444583 scopus 로고
    • Glutathione transferases of classes alpha, mu and pi show selective expression in different regions of rat kidney
    • Rozell, B., Hansson, H. A., Guthenberg, C., Tahir, M. K., and Mannervik, B. (1993). Glutathione transferases of classes alpha, mu and pi show selective expression in different regions of rat kidney. Xenobiotica 23, 835-849.
    • (1993) Xenobiotica , vol.23 , pp. 835-849
    • Rozell, B.1    Hansson, H.A.2    Guthenberg, C.3    Tahir, M.K.4    Mannervik, B.5
  • 45
    • 35848946412 scopus 로고    scopus 로고
    • Controversies in nephrology: response to 'renal albumin handling, facts, and artifacts'
    • Russo, L. M., Sandoval, R. M., Brown, D., Molitoris, B. A., and Comper, W. D. (2007). Controversies in nephrology: response to 'renal albumin handling, facts, and artifacts'. Kidney Int. 72, 1195-1197.
    • (2007) Kidney Int , vol.72 , pp. 1195-1197
    • Russo, L.M.1    Sandoval, R.M.2    Brown, D.3    Molitoris, B.A.4    Comper, W.D.5
  • 48
    • 77954849273 scopus 로고    scopus 로고
    • Application of Dolichos biflorus in immunoassay detection of kidney collecting duct biomarkers
    • Sourial, S., Searchfield, L., Schuppe-Koistinen, I., Betton, G. R., Riccardi, D., and Price, S. A. (2010). Application of Dolichos biflorus in immunoassay detection of kidney collecting duct biomarkers. Biomarkers 15, 424-435.
    • (2010) Biomarkers , vol.15 , pp. 424-435
    • Sourial, S.1    Searchfield, L.2    Schuppe-Koistinen, I.3    Betton, G.R.4    Riccardi, D.5    Price, S.A.6
  • 49
    • 0028139237 scopus 로고
    • Glutathione transferases in the urine: sensitive methods for detection of kidney damage induced by nephrotoxic agents in humans
    • Sundberg, A., Appelkvist, E. L., Dallner, G., and Nilsson, R. (1994a). Glutathione transferases in the urine: sensitive methods for detection of kidney damage induced by nephrotoxic agents in humans. Environ. Health Perspect. 102(Suppl. 3), 293-296.
    • (1994) Environ. Health Perspect. , vol.102 , Issue.SUPPL. 3 , pp. 293-296
    • Sundberg, A.1    Appelkvist, E.L.2    Dallner, G.3    Nilsson, R.4
  • 50
    • 0028175980 scopus 로고
    • Urinary pi-class glutathione transferase as an indicator of tubular damage in the human kidney
    • Sundberg, A. G., Appelkvist, E. L., Backman, L., and Dallner, G. (1994b). Urinary pi-class glutathione transferase as an indicator of tubular damage in the human kidney. Nephron 67, 308-316.
    • (1994) Nephron , vol.67 , pp. 308-316
    • Sundberg, A.G.1    Appelkvist, E.L.2    Backman, L.3    Dallner, G.4
  • 51
    • 0027162781 scopus 로고
    • Immunohistochemical localization of alpha and pi class glutathione transferases in normal human tissues
    • Sundberg, A. G., Nilsson, R., Appelkvist, E. L., and Dallner, G. (1993). Immunohistochemical localization of alpha and pi class glutathione transferases in normal human tissues. Pharmacol. Toxicol. 72, 321-331.
    • (1993) Pharmacol. Toxicol. , vol.72 , pp. 321-331
    • Sundberg, A.G.1    Nilsson, R.2    Appelkvist, E.L.3    Dallner, G.4
  • 52
    • 0024404067 scopus 로고
    • Strain differences in acetaminophen nephrotoxicity in rats: role of pharmacokinetics
    • Tarloff, J. B., Goldstein, R. S., and Hook, J. B. (1989). Strain differences in acetaminophen nephrotoxicity in rats: role of pharmacokinetics. Toxicology 56, 167-177.
    • (1989) Toxicology , vol.56 , pp. 167-177
    • Tarloff, J.B.1    Goldstein, R.S.2    Hook, J.B.3
  • 53
    • 25644434284 scopus 로고    scopus 로고
    • Investigation on urinary proteins and renal mRNA expression in canine renal papillary necrosis induced by nefiracetam
    • Tsuchiya, Y., Tominaga, Y., Matsubayashi, K., Jindo, T., Furuhama, K., and Suzuki, K. T. (2005). Investigation on urinary proteins and renal mRNA expression in canine renal papillary necrosis induced by nefiracetam. Arch. Toxicol. 79, 500-507.
    • (2005) Arch. Toxicol. , vol.79 , pp. 500-507
    • Tsuchiya, Y.1    Tominaga, Y.2    Matsubayashi, K.3    Jindo, T.4    Furuhama, K.5    Suzuki, K.T.6
  • 55
    • 0037341547 scopus 로고    scopus 로고
    • Measurement of tubular enzymuria facilitates early detection of acute renal impairment in the intensive care unit
    • Westhuyzen, J., Endre, Z. H., Reece, G., Reith, D. M., Saltissi, D., and Morgan, T. J. (2003). Measurement of tubular enzymuria facilitates early detection of acute renal impairment in the intensive care unit. Nephrol. Dial. Transplant. 18, 543-551.
    • (2003) Nephrol. Dial. Transplant. , vol.18 , pp. 543-551
    • Westhuyzen, J.1    Endre, Z.H.2    Reece, G.3    Reith, D.M.4    Saltissi, D.5    Morgan, T.J.6
  • 56
    • 1842484217 scopus 로고    scopus 로고
    • 1H-Nuclear magnetic resonance pattern recognition studies with N-phenylanthranilic acid in the rat: time- and dose-related metabolic effects
    • Williams, R. E., Cottrell, L., Jacobsen, M., Bandara, L. R., Kelly, M. D., Kennedy, S., and Lock, E. A. (2003). 1H-Nuclear magnetic resonance pattern recognition studies with N-phenylanthranilic acid in the rat: time- and dose-related metabolic effects. Biomarkers 8, 472-490.
    • (2003) Biomarkers , vol.8 , pp. 472-490
    • Williams, R.E.1    Cottrell, L.2    Jacobsen, M.3    Bandara, L.R.4    Kelly, M.D.5    Kennedy, S.6    Lock, E.A.7
  • 59
    • 0027457620 scopus 로고
    • Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinicalmedicine
    • Zweig, M. H., and Campbell, G. (1993). Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinicalmedicine. Clin.Chem. 39, 561-577.
    • (1993) Clin. Chem. , vol.39 , pp. 561-577
    • Zweig, M.H.1    Campbell, G.2


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