Role of the renal cysteine conjugate β-lyase pathway in inhaled compound a nephrotoxicity in rats

Anesthesiology

Volumn 88, Issue 6, 1998, Pages 1624-1633

  Kharasch, Evan D ^a   Hoffman, Gary M ^b   Thorning, David ^b   Hankins, Douglas C ^b   Kilty, Cormac G ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b NONE

Author keywords

Glutathione S transferase; Haloalkene; Kidney; Metabolism; Sevoflurane

Indexed keywords

1 AMINOBENZOTRIAZOLE; ACIVICIN; AMINOOXYACETIC ACID; BENZOTRIAZOLE DERIVATIVE; COMPOUND A; CYSTEINE CONJUGATE; DRUG METABOLITE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LYASE; PROBENECID; SEVOFLURANE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG METABOLISM; DRUG UPTAKE; ENZYME INHIBITION; GLUCOSURIA; INHALATIONAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY TUBULE NECROSIS; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT;

ANESTHETICS, INHALATION; ANIMALS; BIOLOGICAL MARKERS; BIOTRANSFORMATION; CARBON-SULFUR LYASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ETHERS; HYDROCARBONS, FLUORINATED; KIDNEY; MALE; RATS; RATS, INBRED F344;

EID: 0031777738     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199806000-00027     Document Type: Article

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