Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage

Osteoarthritis and Cartilage

Volumn 17, Issue 4, 2009, Pages 513-517

  Loeser, R F ^a   Im, H J ^b   Richardson, B ^c   Lu, Q ^d   Chubinskaya, S ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Aging; Chondrocyte; Growth factors; Osteoarthritis

Indexed keywords

AGGRECAN; AZACITIDINE; BISULFITE; DNA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; OSTEOGENIC PROTEIN 1; RNA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; BMP7 PROTEIN, HUMAN;

ADULT; AGE; AGED; AGING; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE; CARTILAGE CELL; CELL ISOLATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN METHYLATION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DNA METHYLATION; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PROCEDURES; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AGGRECANS; AGING; AZACITIDINE; BONE MORPHOGENETIC PROTEIN 7; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MIDDLE AGED; PROMOTER REGIONS, GENETIC; RECEPTOR, IGF TYPE 1; YOUNG ADULT;

EID: 61549102182     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2008.08.003     Document Type: Article

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