Electrostatic interactions involving the extreme C terminus of nuclear export factor CRM1 modulate its affinity for cargo

Journal of Biological Chemistry

Volumn 286, Issue 33, 2011, Pages 29325-29335

  Fox, Abigail M ^a   Ciziene, Danguole ^a   McLaughlin, Stephen H ^a   Stewart, Murray ^a  

^a MRC LMB   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC RESIDUES; C TERMINUS; INNER SURFACES; NUCLEAR EXPORT; NUCLEAR EXPORT SIGNALS; NUCLEAR PROTEINS; OUTER SURFACE; SMALL ANGLE X-RAY SCATTERING;

CRYSTAL STRUCTURE; CYTOLOGY;

ELECTROSTATICS;

EXPORTIN 1; GUANOSINE TRIPHOSPHATE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE MUTATION; HUMAN; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR EXPORT SIGNAL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

ACTIVE TRANSPORT, CELL NUCLEUS; BINDING SITES; CELL NUCLEUS; CRYSTALLOGRAPHY, X-RAY; KARYOPHERINS; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STATIC ELECTRICITY;

EID: 80051674080     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.245092     Document Type: Article

References (28)

1. Fornerod, M., Ohno, M., Yoshida, M., and Mattaj, I. W. (1997) Cell 90, 1051-1060
2. Kutay, U., Izaurralde, E., Bischoff, F. R., Mattaj, I. W., and Görlich, D. (1997) EMBO J. 16, 1153-1163
3. Stade, K., Ford, C. S., Guthrie, C., and Weis, K. (1997) Cell 90, 1041-1050
4. Weis, K. (2003) Cell 112, 441-451
5. Kutay, U., and Güttinger, S. (2005) Trends Cell Biol. 15, 121-124
6. Tran, E. J., and Wente, S. R. (2006) Cell 125, 1041-1053
7. Strambio-De-Castillia, C., Niepel, M., and Rout, M. P. (2010) Nat. Rev. Mol. Cell Biol. 11, 490-501
8. Cook, A. G., and Conti, E. (2010) Curr. Opin. Struct. Biol. 20, 247-252
9. Dong, X., Biswas, A., Süel, K. E., Jackson, L. K., Martinez, R., Gu, H., and Chook, Y. M. (2009) Nature 458, 1136-1141
10. Monecke, T. Güttler, T., Neumann, P., Dickmanns, A., Görlich, D., and Ficner, R. (2009) Science 324, 1087-1091
11. Koyama, M., and Matsuura, Y. (2010) EMBO J. 29, 2002-2013
12. Güttler, T., Madl, T. Neumann, P., Deichsel, D., Corsini, L., Monecke, T., Ficner, R., Sattler, M., and Görlich, D. (2010) Nat. Struct. Mol. Biol. 17, 1367-1376
13. Dong, X., Biswas, A., and Chook, Y. M. (2009) Nat. Struct. Mol. Biol. 16, 558-560
14. Matsuura, Y., and Stewart, M. (2004) Nature 432, 872-877
15. Studier, F. W. (2005) Protein Expr. Purif. 41, 207-234
16. Kapust, R. B., Tözsér, J., Fox, J. D., Anderson, D. E., Cherry, S., Copeland, T. D., and Waugh, D. S. (2001) Protein Eng. 14, 993-1000
17. Konarev, P. V., Volkov, V. V., Sokolova, A. V., Koch, M. H., and Svergun, D. I. (2003) J. Appl. Crystallogr. 36, 1277-1282
18. Svergun, D. I., Barberato, C., and Koch, M. H. (1995) J. Appl. Crystallogr. 28, 768-773
19. Sokolova, A. V., Volkov, V. V., and Svergun, D. I. (2003) J. Appl. Crystallogr. 36, 865-868
20. Fukuhara, N., Fernandez, E., Ebert, J., Conti, E., and Svergun, D. I. (2004) J. Biol. Chem. 279, 2176-2181
21. Bayliss, R., Littlewood, T., and Stewart, M. (2000) Cell 102, 99-108
22. Stewart, M. (2007) Nat. Rev. Mol. Cell Biol. 8, 195-208
23. Bischoff, F. R., and Görlich, D. (1997) FEBS Lett. 419, 249-254
24. Bischoff, F. R., and Ponstingl, H. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 10830-10834
25. Matsuura, Y., Lange, A., Harreman, M. T., Corbett, A. H., and Stewart, M. (2003) EMBO J. 22, 5358-5369
26. Matsuura, Y., and Stewart, M. (2005) EMBO J. 24, 3681-3689
27. Paraskeva, E, Izaurralde, E., Bischoff, F. R., Huber, J., Kutay, U., Hartmann, E., Lührmann, R., and Görlich, D. (1999) J. Cell Biol. 145, 255-264
28. Volkov, V. V., and Svergun, D. I. (2003) J. Appl. Crystallogr. 36, 860-864