메뉴 건너뛰기




Volumn 176, Issue 8, 2011, Pages 896-902

The relationship between Gulf war illness, brain N-acetylaspartate, and post-traumatic stress disorder

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; DRUG DERIVATIVE; N ACETYLASPARTIC ACID; N-ACETYLASPARTATE;

EID: 80051659230     PISSN: 00264075     EISSN: None     Source Type: Journal    
DOI: 10.7205/MILMED-D-10-00332     Document Type: Article
Times cited : (31)

References (66)
  • 2
    • 34548647937 scopus 로고    scopus 로고
    • Gulf War illness: Lessons from medically unexplained symptoms
    • Iversen A, Chalder T, Wessely S: Gulf War illness: lessons from medically unexplained symptoms. Clin Psychol Rev 2007; 27: 842-54.
    • (2007) Clin Psychol Rev , vol.27 , pp. 842-854
    • Iversen, A.1    Chalder, T.2    Wessely, S.3
  • 3
    • 14744297261 scopus 로고    scopus 로고
    • Gulf War syndrome: A toxic exposure? A systematic review
    • Gronseth GS: Gulf War syndrome: a toxic exposure? A systematic review. Neurol Clin 2005; 23: 523-40.
    • (2005) Neurol Clin , vol.23 , pp. 523-540
    • Gronseth, G.S.1
  • 4
    • 0033573781 scopus 로고    scopus 로고
    • Health of UK servicemen who served in Persian Gulf War
    • Unwin C, Blatchley N, Coke W, et al: Health of UK servicemen who served in Persian Gulf War. Lancet 1999; 353: 169-78.
    • (1999) Lancet , vol.353 , pp. 169-178
    • Unwin, C.1    Blatchley, N.2    Coke, W.3
  • 5
    • 0034535694 scopus 로고    scopus 로고
    • Relationship of physical symptoms to posttraumatic stress disorder among veterans seeking care for Gulf War-related health concerns
    • Engel CC, Liu X, McCarthy BD, Miller RF, Ursano R: Relationship of physical symptoms to posttraumatic stress disorder among veterans seeking care for Gulf War-related health concerns. Psychosom Med 2000; 62: 739-45.
    • (2000) Psychosom Med , vol.62 , pp. 739-745
    • Engel, C.C.1    Liu, X.2    McCarthy, B.D.3    Miller, R.F.4    Ursano, R.5
  • 6
    • 0034052022 scopus 로고    scopus 로고
    • Health effects of depleted uranium on exposed Gulf War veterans
    • McDiarmid MA, Keogh JP, Hooper FJ, et al: Health effects of depleted uranium on exposed Gulf War veterans. Environ Res 2000; 82: 168-80.
    • (2000) Environ Res , vol.82 , pp. 168-180
    • McDiarmid, M.A.1    Keogh, J.P.2    Hooper, F.J.3
  • 7
    • 0034690737 scopus 로고    scopus 로고
    • Role of vaccinations as risk factors for ill health in veterans of the Gulf War: Cross sectional study
    • Hotopf M, David A, Hull L, Ismail K, Unwin C, Wessely S: Role of vaccinations as risk factors for ill health in veterans of the Gulf War: cross sectional study. BMJ 2000; 320: 1363-7.
    • (2000) BMJ , vol.320 , pp. 1363-1367
    • Hotopf, M.1    David, A.2    Hull, L.3    Ismail, K.4    Unwin, C.5    Wessely, S.6
  • 8
    • 0029850424 scopus 로고    scopus 로고
    • Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response
    • Friedman A, Kaufer D, Shemer J, Hendler I, Soreq H, Tur-Kaspa I: Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response. Nat Med 1996; 2: 1382-5.
    • (1996) Nat Med , vol.2 , pp. 1382-1385
    • Friedman, A.1    Kaufer, D.2    Shemer, J.3    Hendler, I.4    Soreq, H.5    Tur-Kaspa, I.6
  • 9
    • 0029896417 scopus 로고    scopus 로고
    • Neurotoxicity resulting from coexposure to PB, DEET and permethrin: Implications of Gulf War chemical exposures
    • Abou-Donia MB, Wilmarth KR, Jensen KF, Oehme FW, Kurt TL: Neurotoxicity resulting from coexposure to PB, DEET and permethrin: implications of Gulf War chemical exposures. J Toxicol Environ Health 1996; 48: 35-56.
    • (1996) J Toxicol Environ Health , vol.48 , pp. 35-56
    • Abou-Donia, M.B.1    Wilmarth, K.R.2    Jensen, K.F.3    Oehme, F.W.4    Kurt, T.L.5
  • 11
    • 0347063199 scopus 로고    scopus 로고
    • Invited commentary: How would we know a Gulf War syndrome if we saw one?
    • Wegman DH, Woods NF, Bailar JC: Invited commentary: how would we know a Gulf War syndrome if we saw one? Am J Epidemiol 1997; 146: 704-11.
    • (1997) Am J Epidemiol , vol.146 , pp. 704-711
    • Wegman, D.H.1    Woods, N.F.2    Bailar, J.C.3
  • 12
    • 0034801998 scopus 로고    scopus 로고
    • Posttraumatic stress symptomatology is associated with unexplained illness attributed to Persian Gulf War military service
    • Ford JD, Campbell KA, Storzbach D, Binder LM, Anger WK, Rohlman DS: Posttraumatic stress symptomatology is associated with unexplained illness attributed to Persian Gulf War military service. Psychosom Med 2001; 63: 842-9.
    • (2001) Psychosom Med , vol.63 , pp. 842-849
    • Ford, J.D.1    Campbell, K.A.2    Storzbach, D.3    Binder, L.M.4    Anger, W.K.5    Rohlman, D.S.6
  • 13
    • 80051613419 scopus 로고    scopus 로고
    • Scientific Progress in Understanding Gulf War Veterans' Illnesses: Report and Recommendations
    • Washington, DC, Veterans Administration
    • Binns JH, et al: Scientific Progress in Understanding Gulf War Veterans' Illnesses: Report and Recommendations. Research Advisory Committee on Gulf War Veterans' Illnesses. Washington, DC, Veterans Administration, 2004.
    • (2004) Research Advisory Committee On Gulf War Veterans' Illnesses
    • Binns, J.H.1
  • 14
    • 0026147120 scopus 로고
    • A review of chemical issues in 1H NMR spectroscopy: N-acetyl aspartate, creatine and choline
    • Miller BL: A review of chemical issues in 1H NMR spectroscopy: N-acetyl aspartate, creatine and choline. NMR Biomed 1991; 4: 47-52.
    • (1991) NMR Biomed , vol.4 , pp. 47-52
    • Miller, B.L.1
  • 15
    • 0031021513 scopus 로고    scopus 로고
    • Is there a Gulf War syndrome? Searching for syndromes by factor analysis of symptoms
    • Haley RW, Kurt TL, Hom J: Is there a Gulf War syndrome? Searching for syndromes by factor analysis of symptoms. JAMA 1997; 277: 215-22.
    • (1997) JAMA , vol.277 , pp. 215-222
    • Haley, R.W.1    Kurt, T.L.2    Hom, J.3
  • 16
    • 0030293198 scopus 로고    scopus 로고
    • The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin
    • Davies HG, Richter RJ, Keifer M, Broomfield CA, Sowalla J, Furlong CE: The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nat Genet 1996; 14: 334-6.
    • (1996) Nat Genet , vol.14 , pp. 334-336
    • Davies, H.G.1    Richter, R.J.2    Keifer, M.3    Broomfield, C.A.4    Sowalla, J.5    Furlong, C.E.6
  • 17
    • 0033564496 scopus 로고    scopus 로고
    • Association of low PON1 type Q (type A) arylesterase activity with neurologic symptom complexes in Gulf War veterans
    • Haley RW, Billecke S, La Du BN: Association of low PON1 type Q (type A) arylesterase activity with neurologic symptom complexes in Gulf War veterans. Toxicol Appl Pharmacol 1999; 157: 227-33.
    • (1999) Toxicol Appl Pharmacol , vol.157 , pp. 227-233
    • Haley, R.W.1    Billecke, S.2    la Du, B.N.3
  • 19
    • 0030817977 scopus 로고    scopus 로고
    • Neuropsychological correlates of Gulf War syndrome
    • Hom J, Haley RW, Kurt TL: Neuropsychological correlates of Gulf War syndrome. Arch Clin Neuropsychol 1997; 12: 531-44.
    • (1997) Arch Clin Neuropsychol , vol.12 , pp. 531-544
    • Hom, J.1    Haley, R.W.2    Kurt, T.L.3
  • 20
    • 0028833989 scopus 로고
    • The development of a Clinician-Administered PTSD Scale
    • Blake DD, Weathers FW, Nagy LM, et al: The development of a Clinician-Administered PTSD Scale. J Trauma Stress 1995; 8: 75-90.
    • (1995) J Trauma Stress , vol.8 , pp. 75-90
    • Blake, D.D.1    Weathers, F.W.2    Nagy, L.M.3
  • 22
    • 0023807146 scopus 로고
    • Mississippi Scale for Combat-Related Posttraumatic Stress Disorder: Three studies in reliability and validity
    • Keane TM, Caddell JM, Taylor KL: Mississippi Scale for Combat-Related Posttraumatic Stress Disorder: three studies in reliability and validity. J Consult Clin Psychol 1988; 56: 85-90.
    • (1988) J Consult Clin Psychol , vol.56 , pp. 85-90
    • Keane, T.M.1    Caddell, J.M.2    Taylor, K.L.3
  • 23
    • 0023882530 scopus 로고
    • The reliability of alcohol abusers' selfreports of drinking and life events that occurred in the distant past
    • Sobell LC, Sobell MB, Riley DM: The reliability of alcohol abusers' selfreports of drinking and life events that occurred in the distant past. J Stud Alcohol 1988; 49: 225-32.
    • (1988) J Stud Alcohol , vol.49 , pp. 225-232
    • Sobell, L.C.1    Sobell, M.B.2    Riley, D.M.3
  • 27
    • 0003441705 scopus 로고    scopus 로고
    • Ed 3. San Antonio, TX, The Psychological Corporation
    • Wechsler D: Wechsler Memory Scale, Ed 3. San Antonio, TX, The Psychological Corporation, 1997.
    • (1997) Wechsler Memory Scale
    • Wechsler, D.1
  • 29
    • 0000119553 scopus 로고
    • Validity of the Trail Making Test as an indicator of organic brain damage
    • Reitan RM: Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills 1958; 8: 271-6.
    • (1958) Percept Mot Skills , vol.8 , pp. 271-276
    • Reitan, R.M.1
  • 30
    • 0023190525 scopus 로고
    • Relationships between parts A and B of the Trail Making Test
    • Corrigan JD, Hinkeldey MS: Relationships between parts A and B of the Trail Making Test. J Clin Psychol 1987; 43: 402-9.
    • (1987) J Clin Psychol , vol.43 , pp. 402-409
    • Corrigan, J.D.1    Hinkeldey, M.S.2
  • 31
    • 0029143926 scopus 로고
    • Construct validity in the Trail Making Test: What makes Part B harder?
    • Gaudino EA, Geisler MW, Squires NK: Construct validity in the Trail Making Test: what makes Part B harder? J Clin Exp Neuropsychol 1995; 17: 529-35.
    • (1995) J Clin Exp Neuropsychol , vol.17 , pp. 529-535
    • Gaudino, E.A.1    Geisler, M.W.2    Squires, N.K.3
  • 34
    • 0029295139 scopus 로고
    • HNRC Group: The HNRC 500- neuropsychology of HIV infection at different disease stages
    • Heaton RK, Grant I, Butters N; HNRC Group: The HNRC 500- neuropsychology of HIV infection at different disease stages. J Int Neuropsychol Soc 1995; 1: 231-51.
    • (1995) J Int Neuropsychol Soc , vol.1 , pp. 231-251
    • Heaton, R.K.1    Grant, I.2    Butters, N.3
  • 38
    • 0029942169 scopus 로고    scopus 로고
    • Benton Controlled Oral Word Association Test: Reliability and updated norms
    • Ruff RM, Light RH, Parker SB, Levin HS: Benton Controlled Oral Word Association Test: reliability and updated norms. Arch Clin Neuropsychol 1996; 11: 329-38.
    • (1996) Arch Clin Neuropsychol , vol.11 , pp. 329-338
    • Ruff, R.M.1    Light, R.H.2    Parker, S.B.3    Levin, H.S.4
  • 40
    • 0015535146 scopus 로고
    • Revised normative standards of performance of men on a quantitative ataxia test battery
    • Fregly AR, Smith MJ, Graybiel A: Revised normative standards of performance of men on a quantitative ataxia test battery. Acta Otolaryngol 1973; 75: 10-6.
    • (1973) Acta Otolaryngol , vol.75 , pp. 10-16
    • Fregly, A.R.1    Smith, M.J.2    Graybiel, A.3
  • 41
    • 0024389366 scopus 로고
    • The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research
    • Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ: The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 1989; 28: 193-213.
    • (1989) Psychiatry Res , vol.28 , pp. 193-213
    • Buysse, D.J.1    Reynolds, C.F.2    Monk, T.H.3    Berman, S.R.4    Kupfer, D.J.5
  • 42
    • 0002741138 scopus 로고    scopus 로고
    • Psychometric review of the Trauma History Questionnaire (THQ)
    • Edited by Stamm BH. Lutherville, MD, Sidran Press
    • Green BL: Psychometric review of the Trauma History Questionnaire (THQ). In Measurement of Stress, Trauma and Adaptation. Edited by Stamm BH. Lutherville, MD, Sidran Press, 1996.
    • (1996) Measurement of Stress, Trauma and Adaptation
    • Green, B.L.1
  • 43
    • 0001998391 scopus 로고
    • SCL-90-R, Brief symptom inventory, and matching clinical rating scales
    • Edited by Maruish ME. Hillsdale, NJ, Lawrence Erlbaum Associates, Inc
    • Derogatis L, Lazarus L: SCL-90-R, Brief symptom inventory, and matching clinical rating scales. In The Use of Psychological Testing for Treatment Planning and Outcome Assessment, pp 217-48. Edited by Maruish ME. Hillsdale, NJ, Lawrence Erlbaum Associates, Inc., 1994
    • (1994) The Use of Psychological Testing For Treatment Planning and Outcome Assessment , pp. 217-248
    • Derogatis, L.1    Lazarus, L.2
  • 45
    • 63349111252 scopus 로고    scopus 로고
    • The Veterans SF-36 Health Status Questionnaire: Development and application in the Veterans Health Administration
    • Kazis LE: The Veterans SF-36 Health Status Questionnaire: development and application in the Veterans Health Administration. Monitor 2000; 5.
    • (2000) Monitor , pp. 5
    • Kazis, L.E.1
  • 46
    • 0027519674 scopus 로고
    • Trauma-related symptoms in veterans of Operation Desert Storm: A preliminary report
    • Southwick SM, Morgan A, Nagy LM, et al: Trauma-related symptoms in veterans of Operation Desert Storm: a preliminary report. Am J Psychiatry 1993; 150: 1524-8.
    • (1993) Am J Psychiatry , vol.150 , pp. 1524-1528
    • Southwick, S.M.1    Morgan, A.2    Nagy, L.M.3
  • 47
    • 0033461179 scopus 로고    scopus 로고
    • Determination of paraoxonase (PON1) status requires more than genotyping
    • Richter RJ, Furlong CE: Determination of paraoxonase (PON1) status requires more than genotyping. Pharmacogenetics 1999; 9: 745-53.
    • (1999) Pharmacogenetics , vol.9 , pp. 745-753
    • Richter, R.J.1    Furlong, C.E.2
  • 48
    • 17744389229 scopus 로고    scopus 로고
    • Chronic active heavy drinking and family history of problem drinking modulate regional brain tissue volumes
    • Cardenas VA, Studholme C, Meyerhoff DJ, Song E, Weiner MW: Chronic active heavy drinking and family history of problem drinking modulate regional brain tissue volumes. Psychiatry Res 2005; 138: 115-30.
    • (2005) Psychiatry Res , vol.138 , pp. 115-130
    • Cardenas, V.A.1    Studholme, C.2    Meyerhoff, D.J.3    Song, E.4    Weiner, M.W.5
  • 51
    • 0031756714 scopus 로고    scopus 로고
    • Automated spectral analysis III: Application to in vivo proton MR spectroscopy and spectroscopic imaging
    • Soher BJ, Young K, Govindaraju V, Maudsley AA: Automated spectral analysis III: application to in vivo proton MR spectroscopy and spectroscopic imaging. Magn Reson Med 1998; 40: 822-31.
    • (1998) Magn Reson Med , vol.40 , pp. 822-831
    • Soher, B.J.1    Young, K.2    Govindaraju, V.3    Maudsley, A.A.4
  • 52
    • 0033133368 scopus 로고    scopus 로고
    • Agerelated metabolite changes and volume loss in hippocampus by proton MR spectroscopic imaging and MRI neurobiology of aging
    • Schuff N, Amend D, Knowlton R, Norman D, Fein G, Weiner MW: Agerelated metabolite changes and volume loss in hippocampus by proton MR spectroscopic imaging and MRI neurobiology of aging. Neurobiol Aging 1999; 20: 279-85.
    • (1999) Neurobiol Aging , vol.20 , pp. 279-285
    • Schuff, N.1    Amend, D.2    Knowlton, R.3    Norman, D.4    Fein, G.5    Weiner, M.W.6
  • 55
    • 77956224922 scopus 로고    scopus 로고
    • Effects of low-level exposure to sarin and cyclosarin during the 1991 Gulf War on brain function and brain structure in US veterans
    • Chao LL, Rothlind JC, Cardenas VA, Meyerhoff DJ, Weiner MW: Effects of low-level exposure to sarin and cyclosarin during the 1991 Gulf War on brain function and brain structure in US veterans. Neurotoxicology 2010; 31: 493-501.
    • (2010) Neurotoxicology , vol.31 , pp. 493-501
    • Chao, L.L.1    Rothlind, J.C.2    Cardenas, V.A.3    Meyerhoff, D.J.4    Weiner, M.W.5
  • 56
    • 79952037223 scopus 로고    scopus 로고
    • Hippocampal volume differences in Gulf War veterans with current versus lifetime PTSD symptoms
    • Apfel BA, Ross J, Hlavin J, et al: Hippocampal volume differences in Gulf War veterans with current versus lifetime PTSD symptoms. Biol Psychiatry 2011; 69: 541-8.
    • (2011) Biol Psychiatry , vol.69 , pp. 541-548
    • Apfel, B.A.1    Ross, J.2    Hlavin, J.3
  • 57
    • 0003612778 scopus 로고    scopus 로고
    • Burlington, MA, Elsevier Academic Press
    • Ader R: Psychoneuroimmunology. Burlington, MA, Elsevier Academic Press, 2007.
    • (2007) Psychoneuroimmunology
    • Ader, R.1
  • 58
    • 0342748715 scopus 로고    scopus 로고
    • Illnesses among United States veterans of the Gulf War: A population-based survey of 30,000 veterans
    • Kang HK, Mahan CM, Lee KY, Magee CA, Murphy FM: Illnesses among United States veterans of the Gulf War: a population-based survey of 30,000 veterans. J Occup Environ Med 2000; 42: 491-501.
    • (2000) J Occup Environ Med , vol.42 , pp. 491-501
    • Kang, H.K.1    Mahan, C.M.2    Lee, K.Y.3    Magee, C.A.4    Murphy, F.M.5
  • 59
    • 1242330943 scopus 로고    scopus 로고
    • Posttraumatic stress disorder among patients with chronic pain and chronic fatigue
    • Roy-Burne P, Smith WR, Goldberg J, Afari N, Buchwald D: Posttraumatic stress disorder among patients with chronic pain and chronic fatigue. Psychol Med 2004; 34; 363-8.
    • (2004) Psychol Med , vol.34 , pp. 363-368
    • Roy-Burne, P.1    Smith, W.R.2    Goldberg, J.3    Afari, N.4    Buchwald, D.5
  • 60
    • 4143059341 scopus 로고    scopus 로고
    • Posttraumatic stress disorder and physical illness: Results from clinical and epidemiological studies
    • Boscarino JA: Posttraumatic stress disorder and physical illness: results from clinical and epidemiological studies. Ann N Y Acad Sci 2004; 1032: 141-53.
    • (2004) Ann N Y Acad Sci , vol.1032 , pp. 141-153
    • Boscarino, J.A.1
  • 61
    • 69949167946 scopus 로고    scopus 로고
    • Exposure to severe wartime conditions in early life is associated with an increased risk of irritable bowel syndrome: A population-based cohort study
    • Klooker TK, Braak B, Painter RC, et al: Exposure to severe wartime conditions in early life is associated with an increased risk of irritable bowel syndrome: a population-based cohort study. Am J Gastroenterol 2009; 104: 2250-6.
    • (2009) Am J Gastroenterol , vol.104 , pp. 2250-2256
    • Klooker, T.K.1    Braak, B.2    Painter, R.C.3
  • 63
    • 0041621564 scopus 로고    scopus 로고
    • A metabolic basis for fi bromyalgia and its related disorders: The possible role of resistance to thyroid hormone
    • Garrison RL, Breeding PP: A metabolic basis for fi bromyalgia and its related disorders: the possible role of resistance to thyroid hormone. Med Hypotheses 2003; 61: 182-9.
    • (2003) Med Hypotheses , vol.61 , pp. 182-189
    • Garrison, R.L.1    Breeding, P.P.2
  • 64
    • 0036672211 scopus 로고    scopus 로고
    • Prevalence of post-traumatic stress disorder in fi bromyalgia patients: Overlapping syndromes or post-traumatic fi bromyalgia syndrome?
    • Pall ML: Prevalence of post-traumatic stress disorder in fi bromyalgia patients: overlapping syndromes or post-traumatic fi bromyalgia syndrome? Semin Arthritis Rheum 2001; 32: 38-50.
    • (2001) Semin Arthritis Rheum , vol.32 , pp. 38-50
    • Pall, M.L.1
  • 65
    • 0037438677 scopus 로고    scopus 로고
    • Post-traumatic stress disorder and chronic fatigue-like illness among Gulf War veterans: A population-based survey or 30,000 veterans
    • Kang HK, Natelson BH, Clare MM, Lee KY, Murphy FM: Post-traumatic stress disorder and chronic fatigue-like illness among Gulf War veterans: a population-based survey or 30,000 veterans. Am J Epidemiol 2003; 157: 141-8.
    • (2003) Am J Epidemiol , vol.157 , pp. 141-148
    • Kang, H.K.1    Natelson, B.H.2    Clare, M.M.3    Lee, K.Y.4    Murphy, F.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.