Complement opsonization of HIV-1 enhances the uptake by dendritic cells and involves the endocytic lectin and integrin receptor families

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Tjomsland, Veronica ^a   Ellegård, Rada ^a   Che, Karlhans ^a   Hinkula, Jorma ^a   Lifson, Jeffrey D ^b   Larsson, Marie ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4BETA7 INTEGRIN; BETA1 INTEGRIN; BETA7 INTEGRIN; CD4 ANTIGEN; COMPLEMENT; CR3 PROTEIN; DECTIN 1; INTEGRIN; INTEGRIN RECEPTOR; LECTIN RECEPTOR; LFA 1 PROTEIN; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; LECTIN; OPSONIN;

ARTICLE; COMPLEMENT SYSTEM; CONTROLLED STUDY; DENDRITIC CELL; ENDOCYTOSIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; LOW TEMPERATURE; NONHUMAN; OPSONIZATION; VIRUS ATTACHMENT; VIRUS ENTRY; CELL DIFFERENTIATION; CYTOLOGY; IMMUNOLOGY; KINETICS; METABOLISM; VIRION; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIGENS, CD4; CELL DIFFERENTIATION; COMPLEMENT SYSTEM PROTEINS; DENDRITIC CELLS; ENDOCYTOSIS; HIV-1; HUMANS; INTEGRINS; KINETICS; LECTINS, C-TYPE; OPSONIN PROTEINS; RECEPTORS, CELL SURFACE; VIRION; VIRUS INTERNALIZATION;

EID: 80051609942     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023542     Document Type: Article

References (40)

1. Cummings KL, Waggoner SN, Tacke R, Hahn YS, (2007) Role of complement in immune regulation and its exploitation by virus. Viral Immunol 20: 505-524.
2. Bajtay Z, Speth C, Erdei A, Dierich MP, (2004) Cutting edge: productive HIV-1 infection of dendritic cells via complement receptor type 3 (CR3, CD11b/CD18). J Immunol 173: 4775-4778.
3. Stoiber H, Pruenster M, Ammann CG, Dierich MP, (2005) Complement-opsonized HIV: the free rider on its way to infection. Mol Immunol 42: 153-160.
4. Stoiber H, Banki Z, Wilflingseder D, Dierich MP, (2008) Complement-HIV interactions during all steps of viral pathogenesis. Vaccine 26: 3046-3054.
5. Larsson M, (2005) HIV-1 and the hijacking of dendritic cells: a tug of war. Springer Semin Immunopathol 26: 309-328.
6. Steinman RM, (2007) Lasker Basic Medical Research Award. Dendritic cells: versatile controllers of the immune system. Nat Med 13: 1155-1159.
7. Rahimi A, Sepehri H, Pakravesh J, Bahar K, (1999) Quantification of C3 and C4 in infertile men with antisperm antibody in their seminal plasma. Am J Reprod Immunol 41: 330-336.
8. Thieblemont N, Delibrias C, Fischer E, Weiss L, Kazatchkine MD, et al. (1993) Complement enhancement of HIV infection is mediated by complement receptors. Immunopharmacology 25: 87-93.
9. Bouhlal H, Chomont N, Requena M, Nasreddine N, Saidi H, et al. (2007) Opsonization of HIV with complement enhances infection of dendritic cells and viral transfer to CD4 T cells in a CR3 and DC-SIGN-dependent manner. J Immunol 178: 1086-1095.
10. Wilflingseder D, Banki Z, Garcia E, Pruenster M, Pfister G, et al. (2007) IgG opsonization of HIV impedes provirus formation in and infection of dendritic cells and subsequent long-term transfer to T cells. J Immunol 178: 7840-7848.
11. Pruenster M, Wilflingseder D, Banki Z, Ammann CG, Muellauer B, et al. (2005) C-type lectin-independent interaction of complement opsonized HIV with monocyte-derived dendritic cells. Eur J Immunol 35: 2691-2698.
12. Boggiano C, Manel N, Littman DR, (2007) Dendritic cell-mediated trans-enhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN. J Virol 81: 2519-2523.
13. Cavrois M, Neidleman J, Kreisberg JF, Greene WC, (2007) In Vitro Derived Dendritic Cells trans-Infect CD4 T Cells Primarily with Surface-Bound HIV-1 Virions. PLoS Pathog 3: e4.
14. Frank I, Piatak M Jr, Stoessel H, Romani N, Bonnyay D, et al. (2002) Infectious and whole inactivated simian immunodeficiency viruses interact similarly with primate dendritic cells (DCs): differential intracellular fate of virions in mature and immature DCs. J Virol 76: 2936-2951.
15. Felts RL, Narayan K, Estes JD, Shi D, Trubey CM, et al. (2010) 3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells. Proc Natl Acad Sci U S A 107 (30): 13336-41.
16. Yu HJ, Reuter MA, McDonald D, (2008) HIV traffics through a specialized, surface-accessible intracellular compartment during trans-infection of T cells by mature dendritic cells. PLoS Pathog 4: e1000134.
17. Bouhlal H, Chomont N, Haeffner-Cavaillon N, Kazatchkine MD, Belec L, et al. (2002) Opsonization of HIV-1 by semen complement enhances infection of human epithelial cells. J Immunol 169: 3301-3306.
18. Turville SG, Arthos J, Donald KM, Lynch G, Naif H, et al. (2001) HIV gp120 receptors on human dendritic cells. Blood 98: 2482-2488.
19. Gilbert C, Cantin R, Barat C, Tremblay MJ, (2007) Human immunodeficiency virus type 1 replication in dendritic cell-T-cell cocultures is increased upon incorporation of host LFA-1 due to higher levels of virus production in immature dendritic cells. J Virol 81: 7672-7682.
20. Arthos J, Cicala C, Martinelli E, Macleod K, Van Ryk D, et al. (2008) HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells. Nat Immunol 9: 301-309.
21. Mora JR, von Andrian UH, (2006) T-cell homing specificity and plasticity: new concepts and future challenges. Trends Immunol 27: 235-243.
22. Hidalgo A, Chang J, Jang JE, Peired AJ, Chiang EY, et al. (2009) Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury. Nat Med 15: 384-391.
23. Geijtenbeek TB, van Kooyk Y, (2003) DC-SIGN: a novel HIV receptor on DCs that mediates HIV-1 transmission. Curr Top Microbiol Immunol 276: 31-54.
24. Lambert AA, Gilbert C, Richard M, Beaulieu AD, Tremblay MJ, (2008) The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways. Blood 112: 1299-1307.
25. Verbovetski I, Bychkov H, Trahtemberg U, Shapira I, Hareuveni M, et al. (2002) Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7. J Exp Med 196: 1553-1561.
26. Fraser DA, Laust AK, Nelson EL, Tenner AJ, (2009) C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells. J Immunol 183: 6175-6185.
27. Carpentier JL, Lew DP, Paccaud JP, Gil R, Iacopetta B, et al. (1991) Internalization pathway of C3b receptors in human neutrophils and its transmodulation by chemoattractant receptors stimulation. Cell Regul 2: 41-55.
28. Ehlers MR, (2000) CR3: a general purpose adhesion-recognition receptor essential for innate immunity. Microbes Infect 2: 289-294.
29. Amarilyo G, Verbovetski I, Atallah M, Grau A, Wiser G, et al. (2010) iC3b-opsonized apoptotic cells mediate a distinct anti-inflammatory response and transcriptional NF-kappaB-dependent blockade. Eur J Immunol 40 (3): 699-709.
30. Chazal N, Gerlier D, (2003) Virus entry, assembly, budding, and membrane rafts. Microbiol Mol Biol Rev 67: 226-237, table of contents.
31. Nguyen DH, Giri B, Collins G, Taub DD, (2005) Dynamic reorganization of chemokine receptors, cholesterol, lipid rafts, and adhesion molecules to sites of CD4 engagement. Exp Cell Res 304: 559-569.
32. Burton DR, Desrosiers RC, Doms RW, Koff WC, Kwong PD, et al. (2004) HIV vaccine design and the neutralizing antibody problem. Nat Immunol 5: 233-236.
33. van Montfort T, Nabatov AA, Geijtenbeek TB, Pollakis G, Paxton WA, (2007) Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes. J Immunol 178: 3177-3185.
34. Ballana E, Pauls E, Senserrich J, Clotet B, Perron-Sierra F, et al. (2009) Cell adhesion through alphaV-containing integrins is required for efficient HIV-1 infection in macrophages. Blood 113: 1278-1286.
35. Sattentau Q, (2008) HIV's gut feeling. Nat Immunol 9: 225-227.
36. Takada Y, Ye X, Simon S, (2007) The integrins. Genome Biol 8: 215.
37. Turville S, Wilkinson J, Cameron P, Dable J, Cunningham AL, (2003) The role of dendritic cell C-type lectin receptors in HIV pathogenesis. J Leukoc Biol 74: 710-718.
38. McDonald D, Vodicka MA, Lucero G, Svitkina TM, Borisy GG, et al. (2002) Visualization of the intracellular behavior of HIV in living cells. J Cell Biol 159: 441-452.
39. Guay LA, Musoke P, Hom DL, Nakabiito C, Bagenda D, et al. (2002) Phase I/II trial of HIV-1 hyperimmune globulin for the prevention of HIV-1 vertical transmission in Uganda. Aids 16: 1391-1400.
40. Davis GE, (1992) The Mac-1 and p150,95 beta 2 integrins bind denatured proteins to mediate leukocyte cell-substrate adhesion. Exp Cell Res 200: 242-252.