Complement-opsonized HIV: The free rider on its way to infection

Molecular Immunology

Volumn 42, Issue 2, 2005, Pages 153-160

  Stoiber, Heribert ^a,b   Pruenster, Monika ^a,b   Ammann, Christoph G ^a,b   Dierich, Manfred P ^a,b  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

Author keywords

C; CML; complement; Complement; complement mediated lysis; E; erythrocytes; FDC; follicular dendritic cells; HAM; HIV; HIV associated molecule; Infection; Infectious synapse; Pathogenesis

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; CD59 ANTIGEN; COMPLEMENT; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3A RECEPTOR; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT FACTOR H; COMPLEMENT INHIBITOR; COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENT RECEPTOR; DECAY ACCELERATING FACTOR; MEMBRANE COFACTOR PROTEIN; UNCLASSIFIED DRUG;

B LYMPHOCYTE; CELL SURFACE; CHEMOTAXIS; COMPLEMENT ACTIVATION; COMPLEMENT DEPENDENT CYTOTOXICITY; COMPLEMENT SYSTEM; ERYTHROCYTE; HOST PATHOGEN INTERACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION SENSITIVITY; INFLAMMATORY CELL; MOLECULAR DYNAMICS; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; VIRUS PATHOGENESIS; VIRUS TRANSMISSION;

EID: 5444231475     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2004.06.024     Document Type: Short Survey

References (76)

1. Alsenz J., Lambris J.D., Schulz T.F., Dierich M.P. Localization of the complement-component-C3b-binding site and the cofactor activity for factor I in the 38 kDa tryptic fragment of factor H. Biochem. J. 224:1984;389-398
2. Ames R.S., Li Y., Sarau H.M., Nuthulaganti P., Foley J.J., Ellis C., Zeng Z., Su K., Jurewicz A.J., Hertzberg R.P., Bergsma D.J., Kumar C. Molecular cloning and characterization of the human anaphylatoxin C3a receptor. J. Biol. Chem. 271:1996;20231-20234
3. Bouhlal H., Chomont N., Haeffner-Cavaillon N., Kazatchkine M.D., Belec L., Hocini H. Opsonization of HIV-1 by semen complement enhances infection of human epithelial cells. J. Immunol. 169:2002;3301-3306
4. Bouhlal H., Galon J., Kazatchkine M.D., Fridman W.H., Sautes-Fridman C., Haeffner-Cavaillon N. Soluble CD16 inhibits CR3 (CD11b/CD18)-mediated infection of monocytes/macrophages by opsonized primary R5 HIV-1. J. Immunol. 166:2001;3377-3383
5. Boyer V., Delibrias C., Noraz N., Fischer E., Kazatchkine M.D., Desgranges C. Complement receptor type 2 mediates infection of the human CD4-negative Raji B-cell line with opsonized HIV. Scand. J. Immunol. 36:1992;879-883
6. Boyer V., Desgranges C., Trabaud M.A., Fischer E., Kazatchkine M.D. Complement mediates human immunodeficiency virus type 1 infection of a human T cell line in a CD4- and antibody-independent fashion. J. Exp. Med. 173:1991;1151-1158
7. Cherukuri A., Cheng P.C., Sohn H.W., Pierce S.K. The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts. Immunity. 14:2001;169-179
8. Delibrias C.C., Kazatchkine M.D., Fischer E. Evidence for the role of CR1 (CD35), in addition to CR2 (CD21), in facilitating infection of human T cells with opsonized HIV. Scand. J. Immunol. 38:1993;183-189
9. Delibrias C.C., Mouhoub A., Fischer E., Kazatchkine M.D. CR1(CD35) and CR2(CD21) complement C3 receptors are expressed on normal human thymocytes and mediate infection of thymocytes with opsonized human immunodeficiency virus. Eur. J. Immunol. 24:1994;2784-2788
10. Devine D.V. The regulation of complement on cell surfaces. Transfus. Med. Rev. 5:1991;123-131
11. Diamond M.S., Garcia-Aguilar J., Bickford J.K., Corbi A.L., Springer T.A. The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. J. Cell Biol. 120:1993;1031-1043
12. Dierich M.P., Reisfeld R.A. C3-mediated cytoadherence. Formation of C3 receptor aggregates as prerequisite for cell attachment. J. Exp. Med. 142:1975;242-247
13. Dierich M.P., Ebenbichler C.F., Marschang P., Fust G., Thielens N.M., Arlaud G.J. HIV and human complement: mechanisms of interaction and biological implication. Immunol. Today. 14:1993;435-440
14. Doepper S., Stoiber H., Kacani L., Sprinzl G., Steindl F., Prodinger W.M., Dierich M.P. B cell-mediated infection of stimulated and unstimulated autologous T lymphocytes with HIV-1: role of complement. Immunobiology. 202:2000;293-305
15. Dopper S., Wilflingseder D., Prodinger W.M., Stiegler G., Speth C., Dierich M.P., Stoiber H. Mechanism(s) promoting HIV-1 infection of primary unstimulated T lymphocytes in autologous B cell/T cell co-cultures. Eur. J. Immunol. 33:2003;2098-2107
16. Ebenbichler C.F., Thielens N.M., Vornhagen R., Marschang P., Arlaud G.J., Dierich M.P. Human immunodeficiency virus type 1 activates the classical pathway of complement by direct C1 binding through specific sites in the transmembrane glycoprotein gp41. J. Exp. Med. 174:1991;1417-1424
17. Fearon D.T., Carter R.H. The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity. Annu. Rev. Immunol. 13:1995;127-149
18. Frank I., Stoiber H., Godar S., Stockinger H., Steindl F., Katinger H.W., Dierich M.P. Acquisition of host cell-surface-derived molecules by HIV-1. AIDS. 10:1996;1611-1620
19. Geijtenbeek T.B., Kwon D.S., Torensma R., van Vliet S.J., van Duijnhoven G.C., Middel J., Cornelissen I.L., Nottet H.S., KewalRamani V.N., Littman D.R., Figdor C.G., van Kooyk Y. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell. 100:2000;587-597
20. Geijtenbeek T.B., van Duijnhoven G.C., van Vliet S.J., Krieger E., Vriend G., Figdor C.G., van Kooyk Y. Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1. J. Biol. Chem. 277:2002;11314-11320
21. Gerard N.P., Gerard C. The chemotactic receptor for human C5a anaphylatoxin. Nature. 349:1991;614-617
22. Gras G., Richard Y., Roques P., Olivier R., Dormont D. Complement and virus-specific antibody-dependent infection of normal B lymphocytes by human immunodeficiency virus type 1. Blood. 81:1993;1808-1818
23. Gras G.S., Dormont D. Antibody-dependent and antibody-independent complement-mediated enhancement of human immunodeficiency virus type 1 infection in a human. Epstein-Barr virus-transformed B-lymphocytic cell line. J. Virol. 65:1991;541-545
24. Griffin G.E., Leung K., Folks T.M., Kunkel S., Nabel G.J. Activation of HIV gene expression during monocyte differentiation by induction of NF-kappa B. Nature. 339:1989;70-73
25. Haase A.T. Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues. Annu. Rev. Immunol. 17:1999;625-656
26. Haberman A.M., Shlomchik M.J. Reassessing the function of immune-complex retention by follicular dendritic cells. Nat. Rev. Immunol. 3:2003;757-764
27. Heath S.L., Tew J.G., Tew J.G., Szakal A.K., Burton G.F. Follicular dendritic cells and human immunodeficiency virus infectivity. Nature. 377:1995;740-744
28. Hess C., Klimkait T., Schlapbach L., Del Zenero V., Sadallah S., Horakova E., Balestra G., Werder V., Schaefer C., Battegay M., Schifferli J.A. Association of a pool of HIV-1 with erythrocytes in vivo: a cohort study. Lancet. 359:2002;2230-2234
29. Jakubik J.J., Saifuddin M., Takefman D.M., Spear G.T. B lymphocytes in lymph nodes and peripheral blood are important for binding immune complexes containing HIV-1. Immunology. 96:1999;612-619
30. Jakubik J.J., Saifuddin M., Takefman D.M., Spear G.T. Immune complexes containing human immunodeficiency virus type 1 primary isolates bind to lymphoid tissue B lymphocytes and are infectious for T lymphocytes. J. Virol. 74:2000;552-555
31. Joling P., Bakker L.J., Van Strijp J.A., Meerloo T., de Graaf L., Dekker M.E., Goudsmit J., Verhoef J., Schuurman H.J. Binding of human immunodeficiency virus type-1 to follicular dendritic cells in vitro is complement dependent. J. Immunol. 150:1993;1065-1073
32. June R.A., Schade S.Z., Bankowski M.J., Kuhns M., McNamara A., Lint T.F., Landay A.L., Spear G.T. Complement and antibody mediate enhancement of HIV infection by increasing virus binding and provirus formation. AIDS. 5:1991;269-274
33. desArg enhance the susceptibility of monocyte-derived macrophages to HIV infection. J. Immunol. 166:2000;3410-3415
34. Kacani L., Prodinger W.M., Sprinzl G.M., Schwendinger M.G., Spruth M., Stoiber H., Dopper S., Steinhuber S., Steindl F., Dierich M.P. Detachment of human immunodeficiency virus type 1 from germinal centers by blocking complement receptor type 2. J. Virol. 74:2000a;7997-8002
35. Kishore U., Gupta S.K., Perdikoulis M.V., Kojouharova M.S., Urban B.C., Reid K.B. Modular organization of the carboxyl-terminal, globular head region of human C1q A, B, and C chains. J. Immunol. 171:2003;812-820
36. Kojouharova M.S., Tsacheva I.G., Tchorbadjieva M.I., Reid K.B., Kishore U. Localization of ligand-binding sites on human C1q globular head region using recombinant globular head fragments and single-chain antibodies. Biochim. Biophys. Acta. 1652:2003;64-74
37. Krych-Goldberg M., Atkinson J.P. Structure-function relationships of complement receptor type 1. Immunol. Rev. 180:2001;112-122
38. Lach-Trifilieff E., Marfurt J., Schwarz S., Sadallah S., Schifferli J.A. Complement receptor 1 (CD35) on human reticulocytes: normal expression in systemic lupus erythematosus and HIV-infected patients. J. Immunol. 162:1999;7549-7554
39. Marschang P., Kruger U., Ochsenbauer C., Gurtler L., Hittmair A., Bosch V., Patsch J.R., Dierich M.P. Complement activation by HIV-1-infected cells: the role of transmembrane glycoprotein gp41. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 14:1997;102-109
40. Marschang P., Sodroski J., Wurzner R., Dierich M.P. Decay-accelerating factor (CD55) protects human immunodeficiency virus type 1 from inactivation by human complement. Eur. J. Immunol. 25:1995;285-290
41. McDonald D., Wu L., Bohks S.M., KewalRamani V.N., Unutmaz D., Hope T.J. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science. 300:2003;1295-1297
42. Merrill J.E., Koyanagi Y., Chen I.S. Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor. J. Virol. 63:1989;4404-4408
43. Moir S., Malaspina A., Li Y., Chun T.W., Lowe T., Adelsberger J., Baseler M., Ehler L.A., Liu S., Davey R.T. Jr., Mican J.A., Fauci A.S. B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells. J. Exp. Med. 192:2000;637-646
44. Montefiori D.C., Pantaleo G., Fink L.M., Zhou J.T., Zhou J.Y., Bilska M., Miralles G.D., Fauci A.S. Neutralizing and infection-enhancing antibody responses to human immunodeficiency virus type 1 in long-term nonprogressors. J. Infect. Dis. 173:1996;60-67
45. Morgan B.P., Gasque P. Extrahepatic complement biosynthesis: where, when and why? Clin. Exp. Immunol. 107:1997;1-7
46. Nielsen H.V., Christensen J.P., Andersson E.C., Marker O., Thomsen A.R. Expression of type 3 complement receptor on activated CD8+ T cells facilitates homing to inflammatory sites. J. Immunol. 153:1994;2021-2028
47. Pantaleo G., Cohen O.J., Schacker T., Vaccarezza M., Graziosi C., Rizzardi G.P., Kahn J., Fox C.H., Schnittman S.M., Schwartz D.H., Corey L., Fauci A.S. Evolutionary pattern of human immunodeficiency virus (HIV) replication and distribution in lymph nodes following primary infection: implications for antiviral therapy. Nat. Med. 4:1998;341-345
48. Pinter C., Siccardi A.G., Lopalco L., Longhi R., Clivio A. HIV glycoprotein 41 and complement factor H interact with each other and share functional as well as antigenic homology. AIDS Res. Hum. Retroviruses. 11:1995;971-980
49. Prodinger, W.M., Wuerzner, R., Stoiber, H., Dierich, M.P., 2003. Complement. In: Paul, Fundamental Immunology, fifth ed. Lippincott-Raven, Philadelphia, pp. 1077-1105.
50. Reynes M., Aubert J.P., Cohen J.H., Audouin J., Tricottet V., Diebold J., Kazatchkine M.D. Human follicular dendritic cells express CR1, CR2, and CR3 complement receptor antigens. J. Immunol. 135:1985;2687-2694
51. Rizzuto C.D., Sodroski J.G. Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization. J. Virol. 71:1997;4847-4851
52. Robinson W.E. Jr., Montefiori D.C., Mitchell W.M. Will antibody-dependent enhancement of HIV-1 infection be a problem with AIDS vaccines? Lancet. 1:1988;830-831
53. Robinson W.E. Jr., Montefiori D.C., Mitchell W.M. Complement-mediated antibody-dependent enhancement of HIV-1 infection requires CD4 and complement receptors. Virology. 175:1990;600-604
54. Ross T.M., Xu Y., Green T.D., Montefiori D.C., Robinson H.L. Enhanced avidity maturation of antibody to human immunodeficiency virus envelope: DNA vaccination with gp120-C3d fusion proteins. AIDS Res. Hum. Retrovirol. 17:2001;829-835
55. Schmitz J., Zimmer J.P., Kluxen B., Aries S., Bogel M., Gigli I., Schmitz H. Antibody-dependent complement-mediated cytotoxicity in sera from patients with HIV-1 infection is controlled by CD55 and CD59. J. Clin. Invest. 96:1995;1520-1526
56. Spear G.T., Zariffard M.R., Xin J., Saifuddin M. Inhibition of DC-SIGN-mediated trans infection of T cells by mannose-binding lectin. Immunology. 110:2003;80-85
57. Speth C., Stöckl G., Mohsenipour I., Würzner R., Stoiber H., Lass-Flörl C., Dierich M.P. Human immunodeficiency virus type 1 induced expression of complement factors in human astrocytes. J. Virol. 75:2001;2604-2615
58. Stoiber H., Ammann C., Spruth M., Mullauer B., Eberhart A., Harris C.L., Huber C.G., Longhi R., Falkensammer B., Wurzner R., Dierich M.P. Enhancement of complement-mediated lysis by a peptide derived from SCR 13 of complement factor H. Immunobiology. 203:2001a;670-686
59. Stoiber H., Clivio A., Dierich M.P. Role of complement in HIV infection. Annu. Rev. Immunol. 15:1997;649-674
60. Stoiber H., Frank I., Spruth M., Schwendinger M., Mullauer B., Windisch J.M., Schneider R., Katinger H., Ando I., Dierich M.P. Inhibition of HIV-1 infection in vitro by monoclonal antibodies to the complement receptor type 3 (CR3): an accessory role for CR3 during virus entry? Mol. Immunol. 34:1997a;855-863
61. Stoiber H., Kacani L., Speth C., Wurzner R., Dierich M.P. The supportive role of complement in HIV pathogenesis. Immunol. Rev. 180:2001;168-176
62. Stoiber H., Pinter C., Siccardi A.G., Clivio A., Dierich M.P. Efficient destruction of human immunodeficiency virus in human serum by inhibiting the protective action of complement factor H and decay accelerating factor (DAF, CD55). J. Exp. Med. 183:1996;307-310
63. Stoiber H., Speth C., Dierich M.P. Role of complement in the control of HIV dynamics and pathogenesis. Vaccine. 21:2003;77-82
64. Stoiber H., Thielens N.M., Ebenbichler C., Arlaud G.J., Dierich M.P. The envelope glycoprotein of HIV-1 gp120 and human complement protein C1q bind to the same peptides derived from three different regions of gp41, the transmembrane glycoprotein of HIV-1, and share antigenic homology. Eur. J. Immunol. 24:1994;294-300
65. Sullivan B.L., Knopoff E.J., Saifuddin M., Takefman D.M., Saarloos M.N., Sha B.E., Spear G.T. Susceptibility of HIV-1 plasma virus to complement-mediated lysis. Evidence for a role in clearance of virus in vivo. J. Immunol. 157:1996;1791-1798
66. Susal C., Kirschfink M., Kropelin M., Daniel V., Opelz G. Identification of complement activation sites in human immunodeficiency virus type-1 glycoprotein gp120. Blood. 87:1996;2329-2336
67. Szakal A.K., Kosco M.H., Tew J.G. Microanatomy of lymphoid tissue during humoral immune responses: structure function relationships. Annu. Rev. Immunol. 7:1989;91-109
68. Takefman D.M., Sullivan B.L., Sha B.E., Spear G.T. Mechanisms of resistance of HIV-1 primary isolates to complement-mediated lysis. Virology. 246:1998;370-378
69. Tedaldi E.M., Baker R.K., Moorman A.C., Alzola C.F., Furhrer J., McCabe R.E., Wood K.C., Holmberg S.D. Influence of co-infection with hepatitis C virus on morbidity and mortality due to human immunodeficiency virus infection in the era of highly active antiretroviral therapy. Clin. Infect. Dis. 36:2003;363-367
70. Thieblemont N., Haeffner-Cavaillon N., Haeffner A., Cholley B., Weiss L., Kazatchkine M.D. Triggering of complement receptors CR1 (CD35) and CR3 (CD11b/CD18) induces nuclear translocation of NF-kappa B (p50/p65) in human monocytes and enhances viral replication in HIV-infected monocytic cells. J. Immunol. 155:1995;4861-4867
71. Thielens N.M., Tacnet-Delorme P., Arlaud G.J. Interaction of C1q and mannan-binding lectin with viruses. Immunobiology. 205:2002;563-574
72. Toth F.D., Mosborg-Petersen P., Kiss J., Aboagye-Mathiesen G., Zdravkovic M., Hager H., Aranyosi J., Lampe L., Ebbesen P. Antibody-dependent enhancement of HIV-1 infection in human term syncytiotrophoblast cells cultured in vitro. Clin. Exp. Immunol. 96:1994;389-394
73. Tremblay M., Meloche S., Sekaly R.P., Wainberg M.A. Complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in Epstein-Barr virus-carrying B cells. J. Exp. Med. 171:1990;1791-1796
74. Venneker G.T., Asghar S.S. CD59: a molecule involved in antigen presentation as well as downregulation of membrane attack complex. Exp. Clin. Immunogenet. 9:1992;33-47
75. Volanakis J.E. Transcriptional regulation of complement genes. Annu. Rev. Immunol. 13:1995;277-305
76. Werfel T., Oppermann M., Schulze M., Krieger G., Weber M., Götze O. Binding of fluorescein-labeled anaphylatoxin C5a to human peripheral blood, spleen, and bone marrow leukocytes. Blood. 79:1992;152-160