Molecular analysis of globin gene expression in different thalassaemia disorders: Individual variation of βE pre-mRNA splicing determine disease severity

British Journal of Haematology

Volumn 154, Issue 5, 2011, Pages 635-643

  Tubsuwan, Alisa ^a,b   Munkongdee, Thongperm ^a,b   Jearawiriyapaisarn, Natee ^a   Boonchoy, Chanikarn ^a   Winichagoon, Pranee ^a   Fucharoen, Suthat ^a,b   Svasti, Saovaros ^a,c  

^a MAHIDOL UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c NONE   (Thailand)

Author keywords

Haemoglobin E; MRNA; Pre mRNA splicing; Thalassaemia

Indexed keywords

ALPHA GLOBIN; BETA E GLOBIN; BETA GLOBIN; COMPLEMENTARY DNA; GAMMA GLOBIN; GLOBIN; HEMOGLOBIN A; HEMOGLOBIN B; HEMOGLOBIN E; HEMOGLOBIN F; HEMOGLOBIN G; HEMOGLOBIN VARIANT; MESSENGER RNA; MESSENGER RNA PRECURSOR; UNCLASSIFIED DRUG;

ALPHA THALASSEMIA; ARTICLE; BETA THALASSEMIA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOTYPE; HEMOGLOBINOPATHY; HUMAN; HUMAN CELL; INFANT; NEWBORN; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; RETICULOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; SPLICING DEFECT;

ADOLESCENT; ALPHA-GLOBINS; BETA-GLOBINS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; GLOBINS; HUMANS; INFANT; INFANT, NEWBORN; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PRECURSORS; RNA SPLICING; SEVERITY OF ILLNESS INDEX; THALASSEMIA;

EID: 80051598243     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2011.08770.x     Document Type: Article

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