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Volumn 133, Issue 32, 2011, Pages 12426-12429

Small-molecule-dependent split aptamer ligation

Author keywords

[No Author keywords available]

Indexed keywords

APTAMERS; AZIDE-ALKYNE CYCLOADDITION; BIOLOGICAL FLUIDS; DETECTION ASSAY; DNA LIGATION; DOSE-DEPENDENT; HUMAN BLOODS; SALT CONCENTRATION; SMALL MOLECULES; SMALL-MOLECULE BINDINGS;

EID: 80051581780     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja205518e     Document Type: Article
Times cited : (83)

References (32)
  • 21
    • 77950501363 scopus 로고    scopus 로고
    • Ladame and co-workers have demonstrated an elegant example of a DNAlated reaction that is promoted by G-quadruplex formation. However, assembly of the different nucleic acid strands in this example remains solely dependent upon Watson-Crick base-pairing
    • Ladame and co-workers have demonstrated an elegant example of a DNAlated reaction that is promoted by G-quadruplex formation. However, assembly of the different nucleic acid strands in this example remains solely dependent upon Watson-Crick base-pairing: Meguellati, K.; Koripelly, G.; Ladame, S. Angew. Chem., Int. Ed. 2010, 49, 2738-2742
    • (2010) Angew. Chem., Int. Ed. , vol.49 , pp. 2738-2742
    • Meguellati, K.1    Koripelly, G.2    Ladame, S.3
  • 29
    • 24644458830 scopus 로고    scopus 로고
    • The design of split aptamers requires a thermodynamic balance in which the enthalpic gain of base-pairing and base-stacking is not sufficient to offset the entropic cost of duplex formation for the nucleic acids alone, but binding of the target provides the additional enthalpy needed to tip the scales in favor of assembly
    • The design of split aptamers requires a thermodynamic balance in which the enthalpic gain of base-pairing and base-stacking is not sufficient to offset the entropic cost of duplex formation for the nucleic acids alone, but binding of the target provides the additional enthalpy needed to tip the scales in favor of assembly: Yamamoto-Fujita, R.; Kumar, P. K. R. Anal. Chem. 2005, 77, 5460-5466
    • (2005) Anal. Chem. , vol.77 , pp. 5460-5466
    • Yamamoto-Fujita, R.1    Kumar, P.K.R.2
  • 31
    • 77957262028 scopus 로고    scopus 로고
    • See Supporting Information for a full list of mutant sequences. All bases selected for mutation had been shown by footprinting not to be directly involved in cocaine binding in the regular aptamer
    • See Supporting Information for a full list of mutant sequences. All bases selected for mutation had been shown by footprinting not to be directly involved in cocaine binding in the regular aptamer: Neves, M. A. D.; Reinstein, O.; Johnson, P. E. Biochemistry 2010, 49, 8478-8487
    • (2010) Biochemistry , vol.49 , pp. 8478-8487
    • Neves, M.A.D.1    Reinstein, O.2    Johnson, P.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.