Defining a stem length-dependent binding mechanism for the cocaine-binding aptamer. A combined NMR and calorimetry study

Biochemistry

Volumn 49, Issue 39, 2010, Pages 8478-8487

  Neves, Miguel A D ^a   Reinstein, Oren ^a   Johnson, Philip E ^a  

^a YORK UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMERS; BASE PAIRS; BINDING MECHANISMS; CHEMICAL SHIFT PERTURBATIONS; FREEFORMS; HEAT CAPACITIES; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; NMR SPECTROSCOPY; SECONDARY STRUCTURE FORMATION; SECONDARY STRUCTURES; SPECTRAL CHANGE; STEM LENGTH; TERTIARY INTERACTIONS;

CALORIMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SPECTROSCOPY;

LIGANDS;

APTAMER; COCAINE;

ARTICLE; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BINDING SITES; CALORIMETRY; COCAINE; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID CONFORMATION; THERMODYNAMICS;

EID: 77957262028     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100952k     Document Type: Article

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