c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice

American Journal of Respiratory and Critical Care Medicine

Volumn 183, Issue 12, 2011, Pages 1644-1652

  Lindsey, James Y ^a   Ganguly, Koustav ^b,c   Brass, David M ^a   Li, Zhuowei ^a   Potts, Erin N ^a   Degan, Simone ^a   Chen, Huaiyong ^a   Brockway, Brian ^a   Abraham, Soman N ^a   Berndt, Annerose ^d   Stripp, Barry R ^a   Foster, W Michael ^a   Leikauf, George D ^c   Schulz, Holger ^b   Hollingsworth, John W ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Chronic obstructive pulmonary disease; Genetic; SASH; Tyrosine kinase

Indexed keywords

C KIT TYROSINE KINASE; EPITHELIAL CELL ADHESION MOLECULE; IMATINIB; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GENETIC REGULATION; GENETIC VARIABILITY; IN VITRO STUDY; LUNG ALVEOLUS; LUNG COMPLIANCE; LUNG EMPHYSEMA; LUNG FUNCTION; MOUSE; MOUSE MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RESIDUAL VOLUME; SINGLE NUCLEOTIDE POLYMORPHISM; TOTAL LUNG CAPACITY; WILD TYPE;

ANIMALS; EMPHYSEMA; GENETIC PREDISPOSITION TO DISEASE; LUNG; LUNG COMPLIANCE; MICE; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS C-KIT; PULMONARY ALVEOLI;

EID: 80051563922     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201007-1157OC     Document Type: Article

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