Dopamine β-hydroxylase gene associates with stroop color-word task performance in Han Chinese children with attention deficit/hyperactivity disorder

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 156, Issue 6, 2011, Pages 730-736

  Ji, Ning ^a   Shuai, Lan ^a   Chen, Yun ^a   Liu, Lu ^a   Li, Hai Mei ^a   Li, Ze Hua ^a   Yang, Li ^a   Qian, Qiu Jin ^a   Tang, Yi Lang ^b   Cubells, Joseph F ^b   Wang, Yu feng ^a  

^a PEKING UNIVERSITY SIXTH HOSPITAL   (China)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Association; Attention deficit hyperactivity disorder; Cognitive function; Dopamine hydroxylase; Endophenotype

Indexed keywords

DOPAMINE BETA MONOOXYGENASE; PHOSPHODIESTERASE I;

ADOLESCENT; ALLELE; ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; CHINESE; CLINICAL ASSESSMENT TOOL; COGNITION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; REACTION TIME; SINGLE NUCLEOTIDE POLYMORPHISM; TASK PERFORMANCE;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CHILD; CHINA; DOPAMINE BETA-HYDROXYLASE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; STROOP TEST; TASK PERFORMANCE AND ANALYSIS;

EID: 80051562971     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.31215     Document Type: Article

References (44)

1. Ando J, Ono Y, Wright MJ. 2001. Genetic structure of spatial and verbal working memory. Behav Genet 31: 615-624.
2. Arnsten AF, Li BM. 2005. Neurobiology of executive functions: Catecholamine influences on prefrontal cortical functions. Biol Psychiatry 57: 1377-1384.
3. Barkley R, Murphy K. 1998. Attention-deficit hyperactivity disorder: Clinical workbook, 2nd edition. New York: Guilford Publications.
4. Barkley RA, Smith KM, Fischer M, Navia B. 2006. An examination of the behavioral and neuropsychological correlates of three ADHD candidate gene polymorphisms (DRD4 7+, DBH TaqI A2, and DAT1 40bp VNTR) in hyperactive and normal children followed to adulthood. Am J Med Genet Part B 141B: 487-498.
5. Beckson J. 1946. Limitations of the application of the 4-fold table analyses to hospital data. Biometrics 2: 47-53.
6. Bellgrove MA, Hawi Z, Lowe N, Kirley A, Robertson IH, Gill M. 2005. DRD4 gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): Effects of associated alleles at the VNTR and -521 SNP. Am J Med Genet Part B 136B: 81-86.
7. Bellgrove MA, Hawi Z, Gill M, Robertson IH. 2006a. The cognitive genetics of attention deficit hyperactivity disorder (ADHD): Sustained attention as a candidate phenotype. Cortex 42: 838-845.
8. Bellgrove MA, Mattingley JB, Hawi Z, Mullins C, Kirley A, Gill M, et al. 2006b. Impaired temporal resolution of visual attention and dopamine beta hydroxylase genotype in attention-deficit/hyperactivity disorder. Biol Psychiatry 60: 1039-1045.
9. Bhaduri N, Mukhopadhyay K. 2008. Correlation of plasma dopamine beta-hydroxylase activity with polymorphisms in DBH gene: A study on Eastern Indian population. Cell Mol Neurobiol 28: 343-350.
10. Biederman J, Faraone SV. 2005. Attention-deficit hyperactivity disorder. Lancet 366: 237-248.
11. Bourdelat-Parks BN, Anderson GM, Donaldson ZR, Weiss JM, Bonsall RW, Emery MS, et al. 2005. Effects of dopamine beta-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice. Psychopharmacology (Berl) 183: 72-80.
12. Brennan AR, Arnsten AF. 2008. Neuronal mechanisms underlying attention deficit hyperactivity disorder: The influence of arousal on prefrontal cortical function. Ann N Y Acad Sci 1129: 236-245.
13. Chen Y, Wen G, Rao F, Zhang K, Wang L, Rodriguez-Flores JL, et al. 2010. Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure. J Hypertens 28: 76-86.
14. Cools R, Robbins TW. 2004. Chemistry of the adaptive mind. Philos Transact A Math Phys Eng Sci 362: 2871-2888.
15. Craig SP, Buckle VJ, Lamouroux A, Mallet J, Craig IW. 1988. Localization of the human dopamine beta hydroxylase (DBH) gene to chromosome 9q34. Cytogenet Cell Genet 48: 48-50.
16. Cubells JF, Zabetian CP. 2004. Human genetics of plasma dopamine beta-hydroxylase activity: Applications to research in psychiatry and neurology. Psychopharmacology (Berl) 174: 463-476.
17. Doyle AE, Faraone SV, Seidman LJ, Willcutt EG, Nigg JT, Waldman ID, et al. 2005a. Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD? J Child Psychol Psychiatry 46: 774-803.
18. Doyle AE, Willcutt EG, Seidman LJ, Biederman J, Chouinard VA, Silva J, et al. 2005b. Attention-deficit/hyperactivity disorder endophenotypes. Biol Psychiatry 57: 1324-1335.
19. Faraone SV, Khan SA. 2006. Candidate gene studies of attention-deficit/hyperactivity disorder. J Clin Psychiatry 67 (Suppl 8): 13-20.
20. Faraone SV, Perlis RH, Doyle AE, Smoller JW, Goralnick JJ, Holmgren MA, et al. 2005. Molecular genetics of attention-deficit/hyperactivity disorder. Biol Psychiatry 57: 1313-1323.
21. Gaspar P, Berger B, Febvret A, Vigny A, Henry JP. 1989. Catecholamine innervation of the human cerebral cortex as revealed by comparative immunohistochemistry of tyrosine hydroxylase and dopamine-beta-hydroxylase. J Comp Neurol 279: 249-271.
22. Gong Y, Cai T. 1993. Chinese-Wechsler Intelligence Scale for children. Hunan, China: Map Press.
23. Kebir O, Joober R. 2011. Neuropsychological endophenotypes in attention-deficit/hyperactivity disorder: A review of genetic association studies. Eur Arch Psychiatry Clin Neurosci [Epub ahead of print].
24. Kieling C, Roman T, Doyle AE, Hutz MH, Rohde LA. 2006. Association between DRD4 gene and performance of children with ADHD in a test of sustained attention. Biol Psychiatry 60: 1163-1165.
25. Kieling C, Genro JP, Hutz MH, Rohde LA. 2008. The -1021C/T DBH polymorphism is associated with neuropsychological performance among children and adolescents with ADHD. Am J Med Genet Part B 147B: 485-490.
26. Kobayashi K, Kurosawa Y, Fujita K, Nagatsu T. 1989. Human dopamine beta-hydroxylase gene: Two mRNA types having different 3'-terminal regions are produced through alternative polyadenylation. Nucleic Acids Res 17: 1089-1102.
27. Lan S, Li Y, Qing-jiu C, Yu-feng W. 2007. Effect of methylphenidate on executive function for children with attention deficit hy2. J Peking Univ (Health Sci) 39: 293-298.
28. Lansbergen MM, Kenemans JL, van Engeland H. 2007. Stroop interference and attention-deficit/hyperactivity disorder: A review and meta-analysis. Neuropsychology 21: 251-262.
29. Linyan S, Yaoguo G, Hong W, Al E. 2006. Norm of ADHD Diagnostic Scale-Parent Version in Chinese urban children. Chin J Pract Pediatr 21: 833-836.
30. Livak KJ. 1999. Allelic discrimination using fluorogenic probes and the 5' nuclease assay. Genet Anal 14: 143-149.
31. Loo SK, Rich EC, Ishii J, McGough J, McCracken J, Nelson S, et al. 2008. Cognitive functioning in affected sibling pairs with ADHD: Familial clustering and dopamine genes. J Child Psychol Psychiatry 49: 950-957.
32. Orvaschel H. 1985. Psychiatric interviews suitable for use in research with children and adolescents. Psychopharmacol Bull 21: 737-745.
33. Oxenstierna G, Edman G, Iselius L, Oreland L, Ross SB, Sedvall G. 1986. Concentrations of monoamine metabolites in the cerebrospinal fluid of twins and unrelated individuals-A genetic study. J Psychiatr Res 20: 19-29.
34. Shulian X, Hongke S, Zhiping W. 1989. Word fluency: Age difference in adulthood and relationship with word memory. Acta Psychol Sin 21: 337-345.
35. Stroop JR. 1935. Studies of interference in serial verbal reactions. J Exp Psychol 18: 643-662.
36. Swanson J, Oosterlaan J, Murias M, Schuck S, Flodman P, Spence MA, et al. 2000. Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention. Proc Natl Acad Sci USA 97: 4754-4759.
37. Tang Y, Anderson GM, Zabetian CP, Kohnke MD, Cubells JF. 2005. Haplotype-controlled analysis of the association of a non-synonymous single nucleotide polymorphism at DBH (+1603C→T) with plasma dopamine beta-hydroxylase activity. Am J Med Genet Part B 139B: 88-90.
38. Tang Y, Buxbaum SG, Waldman I, Anderson GM, Zabetian CP, Kohnke MD, et al. 2006. A single nucleotide polymorphism at DBH, possibly associated with attention-deficit/hyperactivity disorder, associates with lower plasma dopamine beta-hydroxylase activity and is in linkage disequilibrium with two putative functional single nucleotide polymorphisms. Biol Psychiatry 60: 1034-1038.
39. Tang YL, Epstein MP, Anderson GM, Zabetian CP, Cubells JF. 2007. Genotypic and haplotypic associations of the DBH gene with plasma dopamine beta-hydroxylase activity in African Americans. Eur J Hum Genet 15: 878-883.
40. Willcutt EG, Doyle AE, Nigg JT, Faraone SV, Pennington BF. 2005. Validity of the executive function theory of attention-deficit/hyperactivity disorder: A meta-analytic review. Biol Psychiatry 57: 1336-1346.
41. Wohl M, Boni C, Asch M, Cortese S, Orejarena S, Mouren MC, et al. 2008. Lack of association of the dopamine transporter gene in a French ADHD sample. Am J Med Genet Part B 147B: 1509-1510.
42. Zabetian CP, Anderson GM, Buxbaum SG, Elston RC, Ichinose H, Nagatsu T, et al. 2001. A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: Evidence for a major functional polymorphism at the DBH locus. Am J Hum Genet 68: 515-522.
43. Zhang HB, Wang YF, Li J, Wang B, Yang L. 2004. Association of dopamine beta-hydroxylase polymorphism with attention deficit hyperactivity disorder in children. Beijing Da Xue Xue Bao 36: 290-293.
44. Zhang HB, Wang YF, Li J, Wang B, Yang L. 2005. Association between dopamine beta hydroxylase gene and attention deficit hyperactivity disorder complicated with disruptive behavior disorder. Zhonghua Er Ke Za Zhi 43: 26-30.