Chiral separation of flurbiprofen enantiomers by preparative and simulated moving bed chromatography

Chirality

Volumn 23, Issue 8, 2011, Pages 602-611

  Ribeiro, António E ^a   Gomes, Pedro Sá ^b   Pais, Luís S ^a   Rodrigues, Alírio E ^b  

^a INSTITUTO POLITÉCNICO DE BRAGANÇA   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

chiral separations; flurbiprofen enantiomers; pharmaceutical intermediate; preparative chiral separation; simulated moving bed chromatography

Indexed keywords

ALCOHOL; FLURBIPROFEN; HYDROCARBON; ORGANIC COMPOUND; SOLVENT; TRIFLUOROACETIC ACID;

ADSORPTION; ARTICLE; CHIRALITY; CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); ENANTIOMER; EQUILIBRIUM CONSTANT; ISOTHERM; KINETICS; LABORATORY; MATHEMATICAL ANALYSIS; MEDICAL INSTRUMENTATION; PRIORITY JOURNAL; RACEMIC MIXTURE; SEPARATION TECHNIQUE; SIMULATED MOVING BED CHROMATOGRAPHY; SIMULATION;

AMYLOSE; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPUTER SIMULATION; ETHANOL; FLURBIPROFEN; HEXANES; LINEAR MODELS; PHENYLCARBAMATES; SOLVENTS; STEREOISOMERISM; TRIFLUOROACETIC ACID;

EID: 80051550618     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20978     Document Type: Article

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