Outlet stream swing simulated moving bed: Separation and regeneration regions analysis

Separation Science and Technology

Volumn 45, Issue 16, 2010, Pages 2259-2272

  Gomes, Pedro Sá ^a   Rodrigues, Alírio E ^b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Chiralpak AD; FlexSMB LSRE ; Guaifenesin; OSS; Outlet stream swing; Simulated moving bed; SMB

Indexed keywords

CHIRALPAK AD; GUAIFENESIN; OSS; OUTLET STREAM SWING; SIMULATED MOVING BED; SMB;

EID: 79955129560     PISSN: 01496395     EISSN: 15205754     Source Type: Journal    
DOI: 10.1080/01496395.2010.497525     Document Type: Article

References (27)

1. Broughton, D.B.; Neuzil, R.W.; Pharis, J.M.; Brearley, C.S. (1970) The Parex process for recovering paraxylene. Chemical Engineering Progress, 66 (9): 70-75.
2. Broughton, D.B.; Gerhold, C.G. (1961) Continuous Sorption Process Employing Fixed Bed of Sorbent and Moving Inlets and Outlets. U.S. Patent No. 2,985,589.
3. Seidel-Morgenstern, A.; Keßler, L.C.; Kaspereit, M. (2008) New developments in simulated moving bed chromatography. Chemical Engineering and Technology, 31 (6): 826-837.
4. Sá Gomes, P. (2009) Advances in Simulated Moving Bed: New operating modes; New design methodologies; and Product (FlexSMB-LSRE) development, PhD Thesis - Laboratory of Separation and Reaction Engineering, Faculty of Engineering of the University of Porto: Porto.
5. Sá Gomes, P.; Minceva, M.; Pais, L.S.; Rodrigues, A.E. (2007) Advances in simulated moving bed chromatographic separations. In: Chiral Separation Techniques, 3rd Ed.; Dr. Ganapathy, S., ed.; 181-202.
6. Sá Gomes, P.; Minceva, M.; Rodrigues, A.E. (2006) Simulated moving bed technology: Old and new. Adsorption, 12 (5-6): 375-392.
7. Rajendran, A.; Paredes, G.; Mazzotti, M. (2009) Simulated moving bed chromatography for the separation of enantiomers. Journal of Chromatography A, 1216 (4): 709-738.
8. Zang, Y.; Wankat, P.C. (2002) SMB operation strategy - partial feed. Industrial and Engineering Chemistry Research, 41 (10): 2504-2511.
9. Zang, Y.; Wankat, P.C. (2002) Three-zone simulated moving bed with partial feed and selective withdrawal. Industrial and Engineering Chemistry Research, 41 (21): 5283-5289.
10. Kloppenburg, E.; Gilles, E.D. (1999) A new concept for operating simulated moving-bed processes. Chemical Engineering and Technology, 22 (10): 813-817.
11. Zhang, Z.; Mazzotti, M.; Morbidelli, M. (2003) PowerFeed operation of simulated moving bed units: Changing flow-rates during the switching interval. Journal of Chromatography A, 1006 (1-2): 87-99.
12. Kawajiri, Y.; Biegler, L.T. (2006) Optimization strategies for simulated moving bed and powerfeed processes. AIChE Journal, 52 (4): 1343-1350.
13. Zhang, Z.; Morbidelli, M.; Mazzotti, M. (2004) Experimental assessment of PowerFeed chromatography. AIChE Journal, 50 (3): 625-632.
14. Bae, Y.S.; Lee, C.H. (2006) Partial-discard strategy for obtaining high purity products using simulated moving bed chromatography. Journal of Chromatography A, 1122 (1-2): 161-173.
15. Keßler, L.C.; Seidel-Morgenstern, A. (2008) Improving performance of simulated moving bed chromatography by fractionation and feedback of outlet streams. Journal of Chromatography A, 1207 (1-2): 55-71.
16. Lutin, F.; Bailly, M.; Bar, D. (2002) Process improvements with innovative technologies in the starch and sugar industries. Desalination,148 (1-3): 121-124.
17. Katsuo, S.; Mazzotti, M. (2010) Intermittent simulated moving bed chromatography: 1. Design criteria and cyclic steady-state. Journal of Chromatography A, 1217 (8): 1354-1361.
18. Sá Gomes, P.; Rodrigues, A.E. (2007) Outlet Streams Swing (OSS) and MultiFeed operation of simulated moving beds. Separation Science and Technology, 42 (2): 223-252.
19. Sá Gomes, P.; Silva, V.M.T.; Rodrigues, A.E. (2009) The Outlet Streams Swing Simulated Moving Bed Mode of Operation, in AICHE Annual Meeting: Nashville-TN, USA.
20. Sá Gomes, P.; Zabkova, M.; Zabka, M.; Minceva, M.; Rodrigues, A.E. (2010) Separation of chiral mixtures in real SMB units: The FlexSMB-LSRE1. AIChE Journal, 56 (1): 125-142.
21. Glueckauf, E. (1955) Theory of chromatography. Part 10. Formulae for diffusion into spheres and their application to chromatography. Trans. Faraday Soc., 51: 1540-1551.
22. Wilke, C.R.; Chang, P. (1955) Correlation of diffusion coefficients in dilute solutions. AIChE Journal, 1 (2): 264-270.
23. Perkins, L.R.; Geankoplis, C.J. (1969) Molecular diffusion in a ternary liquid system with the diffusing component dilute. Chemical Engineering Science, 24 (7): 1035-1042.
24. Teja, A.S.; Rice, P. (1981) Generalized corresponding states method for the viscosities of liquid mixtures. Industrial and Engineering Chemistry Fundamentals, 20 (1): 77-81.
25. Danckwerts, P.V. (1953) Continuous flow systems: Distribution of residence times. Chemical Engineering Science, 2 (1): 1-13.
26. Storti, G.; Mazzotti, M.; Morbidelli, M.; Carra, S. (1993) Robust design of binary countercurrent adsorption separation processes. AIChE Journal, 39 (3): 471-492.
27. Azevedo, D.C.S.; Rodrigues, A.E. (1999) Design of a simulated moving bed in the presence of mass-transfer resistances. AIChE Journal, 45 (5): 956-966.