SMB chromatography design using profile advancement factors, miniplant data, and rate-based process simulation

AIChE Journal

Volumn 55, Issue 11, 2009, Pages 2848-2860

  Feist, Shawn D ^a   Hasabnis, Yogesh ^b   Pynnonen, Bruce W ^a   Frank, Timothy C ^a  

^a DOW CHEMICAL COMPANY   (United States)

^b Dow Chemical International Pvt Ltd   (India)

Author keywords

Chromatography; Process design; Process development; Process simulation; Purification; Separation; Simulated moving bed

Indexed keywords

DATA FITS; FIT PARAMETERS; INITIAL VALUES; LINEAR DRIVING FORCE; LUMPED-PARAMETER; MASS TRANSFER COEFFICIENT; MODEL RESULTS; OPERATING CONDITION; PROCESS DATA; PROCESS DEVELOPMENT; PROCESS SIMULATION; PROCESS SIMULATIONS; PROTEIN SEPARATIONS; PULSE TEST; RAPID DEVELOPMENT; RATE BASED MODEL; SIMULATED MOVING BED; SIMULATED MOVING BED CHROMATOGRAPHY; SMB CHROMATOGRAPHY; TWO-STEP PROCEDURE;

ADSORPTION; CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; MASS TRANSFER; PURIFICATION; SEPARATION; SIMULATORS;

PROCESS DESIGN;

EID: 70350648967     PISSN: 00011541     EISSN: 15475905     Source Type: Journal    
DOI: 10.1002/aic.11938     Document Type: Article

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