Palladium-catalyzed construction of polycyclic heterocycles by an alkyne insertion and direct arylation cascade

Synthesis

Volumn , Issue 16, 2011, Pages 2567-2578

  Ohno, Hiroaki ^a,b   Yamamoto, Mio ^a   Iuchi, Mutsumi ^a   Fujii, Nobutaka ^b   Tanaka, Tetsuaki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

fused ring systems; palladium; polycycles; ring closure; tandem reaction

Indexed keywords

ALKYNE INSERTIONS; ARYL GROUP; ARYLATIONS; CASCADE CYCLIZATION; CASCADE REACTIONS; CATALYTIC AMOUNTS; CESIUM CARBONATES; FUSED-RING SYSTEM; GOOD YIELD; HETEROARENES; HETEROCYCLES; PALLADIUM ACETATE; POLYCYCLES; RING CLOSURES; TANDEM REACTION; THIOPHENE RING;

ACETYLENE; CESIUM; ORGANOMETALLICS; PALLADIUM COMPOUNDS; REACTION KINETICS; THIOPHENE;

CYCLIZATION;

1 [ 1 [TERT BUTYL(DIPHENYL)SILYLOXY]ETHYL] 9 METHYL 2 (4 METHYLPHENYLSULFONYL) 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 1 CYCLOHEXYL 2 (4 METHYLPHENYLSULFONYL) 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 1 CYCLOHEXYL 2 (4 METHYLPHENYLSULFONYL) 9 PHENYL 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 1 CYCLOHEXYL 2 METHYLPHENYLSULFONYL 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 1 CYCLOHEXYL 9 (2 HYDROXYPROPAN 2 YL) 2 (4 METHYLPHENYLSULFONYL) 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 1 CYCLOHEXYL 9 (2 HYDROXYPROPAN 2 YL) 2 METHYLSULFONYL 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 1 ISOPROPYL 2 (4 METHYLPHENYLSULFONYL) 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 2 (4 METHYLPHENYLSULFONYL) 1 PENTYL 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 3 ARYL 2 BROMOPROP 2 EN 1 OLS; 4 [BENZYLIDENE] 2 TERT BUTYL 1 (4 METHYLPHENYLSULFONYL) 3 [PENTYLIDENE] 1H PYRROLE; 4 BUTYL 3 CYCLOHEXYL 2 (4 METHYLPHENYLSULFONYL) 5 (2,4,6 TRIMETHYLPHENYLSULFONYL) 1,2,3,5 TETRAHYDROPYRROLO [3,4 B]CARBAZOLE; 4 BUTYL 3 CYCLOHEXYL 2,5 BIS (4 METHYLPHENYLSULFONYL) 1,2,3,5 TETRAHYDROPYRROLO [3,4 B]CARBAZOLE; 4 BUTYL 5 CYCLOHEXYL 1 (2,4,6 TRIMETHYLPHENYLSULFONYL) 6 (4 METHYLPHENYLSULFONYL) 1,5,6,7 TETRAHYDROPYRROLO [3,4 F]INDOLE; 4 BUTYL 5 CYCLOHEXYL 1,6 BIS (4 METHYLPHENYLSULFONYL) 1,5,6,7 TETRAHYDROPYRROLO [3,4 F]INDOLE; 4 BUTYL 5 CYCLOHEXYL 6 (4 METHYLPHENYLSULFONYL) 6,7 DIHYDRO 5H FURO [2,3 F]ISOINDOLE; 4 BUTYL 5 CYCLOHEXYL N,N DIMETHYL 6 (4 METHYLPHENYLSULFONYL) 6,7 DIHYDROPYRROLO [3,4 F]INDOLE 1 (5H) SULFONAMIDE; 8 BUTYL 7 CYCLOHEXYL 1,6 BIS (4 METHYLPHENYLSULFONYL) 1,5,6,7 TETRAHYDROPYRROLO [3,4 F]INDOLE; 9 BUTYL 1 CYCLOHEXYL 2 (4 METHYLPHENYLSULFONYL) 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 9 BUTYL 1 CYCLOHEXYL 6 METHOXY 2 (4 METHYLPHENYLSULFONYL) 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 9 BUTYL 1 CYCLOHEXYL 7 METHOXY 2 (4 METHYLPHENYLSULFONYL) 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; 9 BUTYL 2 (4 METHYLPHENYLSULFONYL) 1 PENTYL 2,3 DIHYDRO 1H BENZO[F]ISOINDOLE; ALKYNE; CESIUM; HETEROCYCLIC COMPOUND; ISOINDOLE DERIVATIVE; N (1 CYCLOHEXYLHEPT 2 YNYL) N (3 PHENYLPROP 2 YNYL)AMINE; N (BUT 2 YNYL) N (3 PHENYLPROP 2 YNYL) 4 METHYLBENZENE SULFONAMIDE; PALLADIUM ACETATE; PYRROLE; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; CYCLOADDITION; ELECTROPHILICITY; HYDROGEN BOND; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; RING CLOSING METATHESIS; SYNTHESIS;

EID: 80051550540     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260098     Document Type: Article

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