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Volumn 18, Issue 8, 2011, Pages 923-931

Genistein, a phytoestrogen, improves total cholesterol, and Synergy, a prebiotic, improves calcium utilization, but there were no synergistic effects

Author keywords

Bone; Cholesterol; Genistein; Prebiotics; Rodents

Indexed keywords

BIOLOGICAL MARKER; CALCIUM; CHOLESTEROL; ESTRADIOL; GENISTEIN; LIPID; PREBIOTIC AGENT; SYNERGY; UNCLASSIFIED DRUG;

EID: 80051549936     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/gme.0b013e3182116e81     Document Type: Article
Times cited : (28)

References (39)
  • 2
    • 35848937549 scopus 로고    scopus 로고
    • Inulin and oligofructose and mineral metabolism: The evidence from animal trials
    • Scholz-Ahrens KE, Schrezenmeir J. Inulin and oligofructose and mineral metabolism: the evidence from animal trials. J Nutr 2007;137:2513S-2523S. (Pubitemid 350058728)
    • (2007) Journal of Nutrition , vol.137 , Issue.11
    • Scholz-Ahrens, K.E.1    Schrezenmeir, J.2
  • 3
    • 0037396405 scopus 로고    scopus 로고
    • Effects of inulin-type fructans of different chain length and type of branching on intestinal absorption and balance of calcium and magnesium in rats
    • DOI 10.1007/s00394-003-0390-x
    • Coudray C, Tressol JC, Gueux E, Rayssiguier Y. Effects of inulin-type fructans of different chain length and type of branching on intestinal absorption and balance of calcium and magnesium in rats. Eur J Nutr 2003;42:91-98. (Pubitemid 36523004)
    • (2003) European Journal of Nutrition , vol.42 , Issue.2 , pp. 91-98
    • Coudray, C.1    Tressol, J.C.2    Gueux, E.3    Rayssiguier, Y.4
  • 4
    • 0942268817 scopus 로고    scopus 로고
    • Nondigestible Oligosaccharides Increase Calcium Absorption and Suppress Bone Resorption in Ovariectomized Rats
    • Zafar TA, Weaver CM, Zhao Y, Martin BR, Wastney ME. Nondigestible oligosaccharides increase calcium absorption and suppress bone resorption in ovariectomized rats. J Nutr 2004;134:399-402. (Pubitemid 38141823)
    • (2004) Journal of Nutrition , vol.134 , Issue.2 , pp. 399-402
    • Zafar, T.A.1    Weaver, C.M.2    Zhao, Y.3    Martin, B.R.4    Wastney, M.E.5
  • 5
    • 0025458150 scopus 로고
    • Mechanisms and experimental and epidemiological evidence relating dietary fibre (non-starch polysaccharides) and starch to protection against large bowel cancer
    • Bingham SA. Mechanisms and experimental and epidemiological evidence relating dietary fibre (non-starch polysaccharides) and starch to protection against large bowel cancer. Proc Nutr Soc 1990;49:153-171.
    • (1990) Proc Nutr Soc , vol.49 , pp. 153-171
    • Bingham, S.A.1
  • 6
    • 26944445029 scopus 로고    scopus 로고
    • Mechanisms underlying the effects of inulin-type fructans on calcium absorption in the large intestine of rats
    • DOI 10.1016/j.bone.2005.05.015, PII S8756328205002498
    • Raschka L, Daniel H. Mechanisms underlying the effects of inulin-type fructans on calcium absorption in the large intestine of rats. Bone 2005;37:728-735. (Pubitemid 41476396)
    • (2005) Bone , vol.37 , Issue.5 , pp. 728-735
    • Raschka, L.1    Daniel, H.2
  • 8
    • 33645732837 scopus 로고    scopus 로고
    • Nutraceuticals - An emerging era in the treatment and prevention of cardiovascular diseases
    • DOI 10.2174/138920106775789647
    • Ramaa CS, Shirode AR, Mundada AS, Kadam VJ. NutraceuticalsVan emerging era in the treatment and prevention of cardiovascular diseases. Curr Pharm Biotechnol 2006;7:15-23. (Pubitemid 44110362)
    • (2006) Current Pharmaceutical Biotechnology , vol.7 , Issue.1 , pp. 15-23
    • Ramaa, C.S.1    Shirode, A.R.2    Mundada, A.S.3    Kadam, V.J.4
  • 9
    • 70349918167 scopus 로고    scopus 로고
    • Antiresorptive effects of phytoestrogen supplements compared with estradiol or risedronate in postmenopausal women using 41Ca methodology
    • Weaver CM, Martin BR, Jackson GS, et al. Antiresorptive effects of phytoestrogen supplements compared with estradiol or risedronate in postmenopausal women using 41Ca methodology. J Clin Endocrinol Metab 2009;94:3798-3805.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3798-3805
    • Weaver, C.M.1    Martin, B.R.2    Jackson, G.S.3
  • 11
    • 0036785298 scopus 로고    scopus 로고
    • Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: A randomized double-blind placebo-controlled study
    • Morabito N, Crisafulli A, Vergara C, et al. Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study. J Bone Miner Res 2002;17:1904-1912.
    • (2002) J Bone Miner Res , vol.17 , pp. 1904-1912
    • Morabito, N.1    Crisafulli, A.2    Vergara, C.3
  • 12
    • 41949105172 scopus 로고    scopus 로고
    • Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice
    • Liu J, Xu K, Wen G, et al. Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice. Bone 2008;42: 950-959.
    • (2008) Bone , vol.42 , pp. 950-959
    • Liu, J.1    Xu, K.2    Wen, G.3
  • 15
    • 34249072897 scopus 로고    scopus 로고
    • The bone-protective effect of the phytoestrogen genistein is mediated via ERα-dependent mechanisms and strongly enhanced by physical activity
    • DOI 10.1016/j.bone.2007.02.006, PII S8756328207000646
    • Hertrampf T, Gruca MJ, Seibel J, Laudenbach U, Fritzemeier KH, Diel P. The bone-protective effect of the phytoestrogen genistein is mediated via ER->Ydependent mechanisms and strongly enhanced by physical activity. Bone 2007;40:1529-1535. (Pubitemid 46779003)
    • (2007) Bone , vol.40 , Issue.6 , pp. 1529-1535
    • Hertrampf, T.1    Gruca, M.J.2    Seibel, J.3    Laudenbach, U.4    Fritzemeier, K.H.5    Diel, P.6
  • 16
    • 34848922689 scopus 로고    scopus 로고
    • Genistein stimulates osteoblastic differentiation via p38 MAPK-Cbfa1 pathway in bone marrow culture
    • Liao QC, Xiao ZS, Qin YF, Zhou HH. Genistein stimulates osteoblastic differentiation via p38 MAPK-Cbfa1 pathway in bone marrow culture. Acta Pharmacol Sin 2007;28:1597-1602.
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 1597-1602
    • Liao, Q.C.1    Xiao, Z.S.2    Qin, Y.F.3    Zhou, H.H.4
  • 17
    • 0038360744 scopus 로고    scopus 로고
    • Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors α and β
    • DOI 10.1002/jcb.10539
    • Rickard DJ, Monroe DG, Ruesink TJ, Khosla S, Riggs BL, Spelsberg TC. Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors > and A. J Cell Biochem2003;89:633-646. (Pubitemid 36648784)
    • (2003) Journal of Cellular Biochemistry , vol.89 , Issue.3 , pp. 633-646
    • Rickard, D.J.1    Monroe, D.G.2    Ruesink, T.J.3    Khosla, S.4    Riggs, B.L.5    Spelsberg, T.C.6
  • 18
    • 41449115158 scopus 로고    scopus 로고
    • Effects of botanical dietary supplements on cardiovascular, cognitive, and metabolic function in males and females
    • DOI 10.1016/j.genm.2008.03.008, PII S1550857908000090
    • Carlson S, Peng N, Prasain JK, Wyss JM. Effects of botanical dietary supplements on cardiovascular, cognitive, and metabolic function in males and females. Gend Med 2008;5:S76-S90. (Pubitemid 351455233)
    • (2008) Gender Medicine , vol.5 , Issue.SUPPL. 1
    • Carlson, S.1    Peng, N.2    Prasain, J.K.3    Wyss, J.M.4
  • 19
    • 0034056131 scopus 로고    scopus 로고
    • Dietary soy-derived isoflavone phytoestrogens: Could they have a role in coronary heart disease prevention?
    • DOI 10.1016/S0006-2952(99)00409-8, PII S0006295299004098
    • Tikkanen MJ, Adlercreutz H. Dietary soy-derived isoflavone phytoestrogens. Could they have a role in coronary heart disease prevention? Biochem Pharmacol 2000;60:1-5. (Pubitemid 30243079)
    • (2000) Biochemical Pharmacology , vol.60 , Issue.1 , pp. 1-5
    • Tikkanen, M.J.1    Adlercreutz, H.2
  • 22
    • 0036303623 scopus 로고    scopus 로고
    • A combination of dietary fructooligosaccharides and isoflavone conjugates increases femoral bone mineral density and equol production in ovariectomized mice
    • Ohta A, Uehara M, Sakai K, et al. A combination of dietary fructooligosaccharides and isoflavone conjugates increases femoral bone mineral density and equol production in ovariectomized mice. J Nutr 2002;132: 2048-2054. (Pubitemid 34742898)
    • (2002) Journal of Nutrition , vol.132 , Issue.7 , pp. 2048-2054
    • Ohta, A.1    Uehara, M.2    Sakai, K.3    Takasaki, M.4    Adlercreutz, H.5    Morohashi, T.6    Ishimi, Y.7
  • 23
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993;123:1939-1951. (Pubitemid 23342492)
    • (1993) Journal of Nutrition , vol.123 , Issue.11 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey Jr., G.C.3
  • 24
    • 70349308391 scopus 로고    scopus 로고
    • Supplemental dietary racemic equol has modest benefits to bone but has mild uterotropic activity in ovariectomized rats
    • Legette LL, Martin BR, Shahnazari M, et al. Supplemental dietary racemic equol has modest benefits to bone but has mild uterotropic activity in ovariectomized rats. J Nutr 2009;139:1908-1913.
    • (2009) J Nutr , vol.139 , pp. 1908-1913
    • Legette, L.L.1    Martin, B.R.2    Shahnazari, M.3
  • 26
    • 0033052877 scopus 로고    scopus 로고
    • Zinc absorption, distribution, excretion, and retention by healthy preterm infants
    • Wastney ME, Angelus PA, Barnes RM, Subramanian KN. Zinc absorption, distribution, excretion, and retention by healthy preterm infants. Pediatr Res 1999;45:191-196. (Pubitemid 29075994)
    • (1999) Pediatric Research , vol.45 , Issue.2 , pp. 191-196
    • Wastney, M.E.1    Angelus, P.A.2    Barnes, R.M.3    Siva Subramanian, K.N.4
  • 27
    • 0027165564 scopus 로고
    • Relationship of colonic luminal short-chain fatty acids and pH to in vivo cell proliferation in rats
    • Lupton JR, Kurtz PP. Relationship of colonic luminal short-chain fatty acids and pH to in vivo cell proliferation in rats. J Nutr 1993;123: 1522-1530. (Pubitemid 23268004)
    • (1993) Journal of Nutrition , vol.123 , Issue.9 , pp. 1522-1530
    • Lupton, J.R.1    Kurtz, P.P.2
  • 29
    • 33747164818 scopus 로고    scopus 로고
    • A Meta-Analysis of the Effect of Soy Protein Supplementation on Serum Lipids
    • DOI 10.1016/j.amjcard.2006.03.042, PII S000291490600991X
    • Reynolds K, Chin A, Lees KA, Nguyen A, Bujnowski D, He J. A metaanalysis of the effect of soy protein supplementation on serum lipids. Am J Cardiol 2006;98:633-640. (Pubitemid 44233460)
    • (2006) American Journal of Cardiology , vol.98 , Issue.5 , pp. 633-640
    • Reynolds, K.1    Chin, A.2    Lees, K.A.3    Nguyen, A.4    Bujnowski, D.5    He, J.6
  • 30
    • 0036045914 scopus 로고    scopus 로고
    • Effects of consumption of probiotics and prebiotics on serum lipid levels in humans
    • DOI 10.1080/10409230290771519
    • Pereira DI, Gibson GR. Effects of consumption of probiotics and prebiotics on serum lipid levels in humans. Crit Rev Biochem Mol Biol 2002;37:259-281. (Pubitemid 35013422)
    • (2002) Critical Reviews in Biochemistry and Molecular Biology , vol.37 , Issue.4 , pp. 259-281
    • Pereira, D.I.A.1    Gibson, G.R.2
  • 31
    • 67449150166 scopus 로고    scopus 로고
    • Effects of aglycone genistein in a rat experimental model of postmenopausal metabolic syndrome
    • Bitto A, Altavilla D, Bonaiuto A, et al. Effects of aglycone genistein in a rat experimental model of postmenopausal metabolic syndrome. J Endocrinol 2009;200:367-376.
    • (2009) J Endocrinol , vol.200 , pp. 367-376
    • Bitto, A.1    Altavilla, D.2    Bonaiuto, A.3
  • 32
    • 57349120714 scopus 로고    scopus 로고
    • Effects of genistein aglycone in osteoporotic, ovariectomized rats: A comparison with alendronate, raloxifene and oestradiol
    • Bitto A, Burnett BP, Polito F, et al. Effects of genistein aglycone in osteoporotic, ovariectomized rats: a comparison with alendronate, raloxifene and oestradiol. Br J Pharmacol 2008;155:896-905.
    • (2008) Br J Pharmacol , vol.155 , pp. 896-905
    • Bitto, A.1    Burnett, B.P.2    Polito, F.3
  • 33
    • 46849116642 scopus 로고    scopus 로고
    • Effects of genistein on vertebral trabecular bone microstructure, bone mineral density, microcracks, osteocyte density, and bone strength in ovariectomized rats
    • DOI 10.1007/s00774-007-0830-4
    • Dai R, Ma Y, Sheng Z, et al. Effects of genistein on vertebral trabecular bone microstructure, bone mineral density, microcracks, osteocyte density, and bone strength in ovariectomized rats. J Bone Miner Metab 2008; 26:342-349. (Pubitemid 351953024)
    • (2008) Journal of Bone and Mineral Metabolism , vol.26 , Issue.4 , pp. 342-349
    • Dai, R.1    Ma, Y.2    Sheng, Z.3    Jin, Y.4    Zhang, Y.5    Fang, L.6    Fan, H.7    Liao, E.8
  • 34
    • 43249086703 scopus 로고    scopus 로고
    • Comparative effects of 17β-estradiol, raloxifene and genistein on bone 3D microarchitecture and volumetric bone mineral density in the ovariectomized mice
    • DOI 10.1007/s00198-007-0498-6
    • Cano A, Dapia S, Noguera I, et al. Comparative effects of 17A-estradiol, raloxifene, and genistein on bone 3D microarchitecture and volumetric bone mineral density in the ovariectomized mice. Osteoporos Int 2008;19:793-800. (Pubitemid 351652523)
    • (2008) Osteoporosis International , vol.19 , Issue.6 , pp. 793-800
    • Cano, A.1    Dapia, S.2    Noguera, I.3    Pineda, B.4    Hermenegildo, C.5    Del Val, R.6    Caeiro, J.R.7    Garcia-Perez, M.A.8
  • 35
    • 72249103224 scopus 로고    scopus 로고
    • Genistein and a soy extract differentially affect three-dimensional bone parameters and bone-specific gene expression in ovariectomized mice
    • Zhang Y, Li Q, Wan HY, Helferich WG, Wong MS. Genistein and a soy extract differentially affect three-dimensional bone parameters and bone-specific gene expression in ovariectomized mice. J Nutr 2009;139: 2230-2236.
    • (2009) J Nutr , vol.139 , pp. 2230-2236
    • Zhang, Y.1    Li, Q.2    Wan, H.Y.3    Helferich, W.G.4    Wong, M.S.5
  • 36
    • 0028709509 scopus 로고
    • Effects of fructooligosaccharides on the absorption of magnesium and calcium by cecectomized rats
    • Ohta A, Ohtuki M, Takizawa T, Inaba H, Adachi T, Kimura S. Effects of fructooligosaccharides on the absorption of magnesium and calcium by cecectomized rats. Int J Vitam Nutr Res 1994;64:316-323.
    • (1994) Int J Vitam Nutr Res , vol.64 , pp. 316-323
    • Ohta, A.1    Ohtuki, M.2    Takizawa, T.3    Inaba, H.4    Adachi, T.5    Kimura, S.6
  • 37
    • 16444363281 scopus 로고    scopus 로고
    • Novel physiological function of fructooligosaccharides
    • Tokunaga T. Novel physiological function of fructooligosaccharides. Biofactors 2004;21:89-94. (Pubitemid 40921832)
    • (2004) BioFactors , vol.21 , Issue.1-4 , pp. 89-94
    • Tokunaga, T.1
  • 38
    • 0035098152 scopus 로고    scopus 로고
    • Dietary fructooligosaccharides modify intestinal bioavailability of a single dose of genistein and daidzein and affect their urinary excretion and kinetics in blood of rats
    • Uehara M, Ohta A, Sakai K, Suzuki K, Watanabe S, Adlercreutz H. Dietary fructooligosaccharides modify intestinal bioavailability of a single dose of genistein and daidzein and affect their urinary excretion and kinetics in blood of rats. J Nutr 2001;131:787-795. (Pubitemid 32199146)
    • (2001) Journal of Nutrition , vol.131 , Issue.3 , pp. 787-795
    • Uehara, M.1    Ohta, A.2    Sakai, K.3    Suzuki, K.4    Watanabe, S.5    Adlercreutz, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.