The epithelia-specific membrane trafficking factor AP-1B controls gut immune homeostasis in mice

Gastroenterology

Volumn 141, Issue 2, 2011, Pages 621-632

  Takahashi, Daisuke ^a,b   Hase, Koji ^a,b,c   Kimura, Shunsuke ^b   Nakatsu, Fubito ^d   Ohmae, Masumi ^b   Mandai, Yasushi ^e   Sato, Toru ^e   Date, Yasuhiro ^b   Ebisawa, Masashi ^a,b   Kato, Tamotsu ^a,b   Obata, Yuuki ^b   Fukuda, Shinji ^a,b   Kawamura, Yuki I ^f   Dohi, Taeko ^f   Katsuno, Tatsuro ^e   Yokosuka, Osamu ^e   Waguri, Satoshi ^g   Ohno, Hiroshi ^a,b  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CHIBA UNIVERSITY   (Japan)

^f NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^g FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

Author keywords

IgA; Immune Response; Inflammatory Bowel Disease; T Cell

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN 1B; IMMUNOGLOBULIN A; INTERLEUKIN 17; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CLINICAL ARTICLE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITHELIUM CELL; HOMEOSTASIS; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; INTESTINE; MEMBRANE TRANSPORT; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; TH17 CELL;

EID: 80051535555     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.04.056     Document Type: Article

References (33)

1. M.F. Kagnoff, and L. Eckmann Epithelial cells as sensors for microbial infection J Clin Invest 100 1997 6 10 (Pubitemid 27311236)
2. M.T. Abreu Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function Nat Rev Immunol 10 2010 131 144
3. J.K. Kolls, P.B. McCray Jr, and Y.R. Chan Cytokine-mediated regulation of antimicrobial proteins Nat Rev Immunol 8 2008 829 835
4. S. Shimada, M. Kawaguchi-Miyashita, and A. Kushiro Generation of polymeric immunoglobulin receptor-deficient mouse with marked reduction of secretory IgA J Immunol 163 1999 5367 5373
5. A. Nenci, C. Becker, and A. Wullaert Epithelial NEMO links innate immunity to chronic intestinal inflammation Nature 446 2007 557 561 (Pubitemid 46514732)
6. R. Kajino-Sakamoto, M. Inagaki, and E. Lippert Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis J Immunol 181 2008 1143 1152
7. J. Wehkamp, E.F. Stange, and K. Fellermann Defensin-immunology in inflammatory bowel disease Gastroenterol Clin Biol 33 Suppl 3 2009 S137 S144
8. M.A. De Matteis, and A. Luini Exiting the Golgi complex Nat Rev Mol Cell Biol 9 2008 273 284 (Pubitemid 351430855)
9. E. Cario, D. Brown, and M. McKee Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium Am J Pathol 160 2002 165 173 (Pubitemid 34052277)
10. J.A. Doumanov, M. Daubrawa, and H. Unden Identification of a basolateral sorting signal within the cytoplasmic domain of the interleukin-6 signal transducer gp130 Cell Signal 18 2006 1140 1146 (Pubitemid 43674035)
11. A.L. Humlicek, L.J. Manzel, and C.L. Chin Paracellular permeability restricts airway epithelial responses to selectively allow activation by mediators at the basolateral surface J Immunol 178 2007 6395 6403 (Pubitemid 46717423)
12. I. Mellman, and W.J. Nelson Coordinated protein sorting, targeting and distribution in polarized cells Nat Rev Mol Cell Biol 9 2008 833 845
13. H. Folsch, H. Ohno, and J.S. Bonifacino A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells Cell 99 1999 189 198 (Pubitemid 29491785)
14. H. Ohno, T. Tomemori, and F. Nakatsu Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells FEBS Lett 449 1999 215 220 (Pubitemid 29192909)
15. I.I. Ivanov, K. Atarashi, and N. Manel Induction of intestinal Th17 cells by segmented filamentous bacteria Cell 139 2009 485 498
16. S. Vetrano, M. Rescigno, and M.R. Cera Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease Gastroenterology 135 2008 173 184 (Pubitemid 351899025)
17. J.R. Turner Intestinal mucosal barrier function in health and disease Nat Rev Immunol 9 2009 799 809
18. L.V. Hooper, and A.J. Macpherson Immune adaptations that maintain homeostasis with the intestinal microbiota Nat Rev Immunol 10 2010 159 169
19. K.E. Mostov Transepithelial transport of immunoglobulins Annu Rev Immunol 12 1994 63 84 (Pubitemid 24140409)
20. P.J. Cejas, M.C. Walsh, and E.L. Pearce TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2 Blood 115 2010 4750 4757
21. C.Y. Kao, Y. Chen, and P. Thai IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways J Immunol 173 2004 3482 3491 (Pubitemid 39142059)
22. I. Treede, A. Braun, and P. Jeliaskova TNF-alpha-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells BMC Gastroenterol 9 2009 53
23. D. Gravotta, A. Deora, and E. Perret AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells Proc Natl Acad Sci U S A 104 2007 1564 1569 (Pubitemid 46214630)
24. R.C. Aguilar, M. Boehm, and I. Gorshkova Signal-binding specificity of the mu4 subunit of the adaptor protein complex AP-4 J Biol Chem 276 2001 13145 13152
25. F. Luton, and K.E. Mostov Transduction of basolateral-to-apical signals across epithelial cells: ligand-stimulated transcytosis of the polymeric immunoglobulin receptor requires two signals Mol Biol Cell 10 1999 1409 1427 (Pubitemid 29230899)
26. N.H. Salzman, D. Ghosh, and K.M. Huttner Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin Nature 422 2003 522 526 (Pubitemid 36433647)
27. J.W. Lee, P. Wang, and M.G. Kattah Differential regulation of chemokines by IL-17 in colonic epithelial cells J Immunol 181 2008 6536 6545
28. H. Ishigame, S. Kakuta, and T. Nagai Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses Immunity 30 2009 108 119
29. Y. Zheng, P.A. Valdez, and D.M. Danilenko Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens Nat Med 14 2008 282 289 (Pubitemid 351347912)
30. G. Pickert, C. Neufert, and M. Leppkes STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing J Exp Med 206 2009 1465 1472
31. S. Fagarasan, M. Muramatsu, and K. Suzuki Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora Science 298 2002 1424 1427 (Pubitemid 35346143)
32. D.L. Delacroix, G.N. Malburny, and J.P. Vaerman Hepatobiliary transport of plasma IgA in the mouse: contribution to clearance of intravascular IgA Eur J Immunol 15 1985 893 899 (Pubitemid 15229754)
33. E. Orzech, K. Schlessinger, and A. Weiss Interactions of the AP-1 Golgi adaptor with the polymeric immunoglobulin receptor and their possible role in mediating brefeldin A-sensitive basolateral targeting from the trans-Golgi network J Biol Chem 274 1999 2201 2215