Prognosis of patients with hepatocellular carcinoma after hepatic resection: Are elderly patients suitable for surgery?

Journal of Surgical Oncology

Volumn 104, Issue 3, 2011, Pages 284-291

  Nanashima, Atsushi ^a   Abo, Takafumi ^a   Nonaka, Takashi ^a   Fukuoka, Hidetoshi ^a   Hidaka, Shigekazu ^a   Takeshita, Hiroaki ^a   Ichikawa, Tatsuki ^a   Sawai, Terumitsu ^a   Yasutake, Toru ^a   Nakao, Kazuhiko ^a   Nagayasu, Takeshi ^a  

^a NAGASAKI UNIVERSITY HOSPITAL   (Japan)

Author keywords

elderly patients; hepatectomy; hepatocellular carcinoma; prognosis

Indexed keywords

ADULT; AGE SPECIFIC CARE; AGED; ANGINA PECTORIS; ARTICLE; ASCITES; ATELECTASIS; BILE LEAKAGE; CANCER PATIENT; CANCER SURGERY; CANCER SURVIVAL; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GERIATRIC SURGERY; HEART ARRHYTHMIA; HUMAN; ILEUS; INFLAMMATION; KIDNEY DYSFUNCTION; LIVER CELL CARCINOMA; LIVER FAILURE; LIVER RESECTION; LUNG INFARCTION; MAJOR CLINICAL STUDY; MALE; PHYSICAL CAPACITY; PNEUMONIA; PORTAL VEIN THROMBOSIS; POSTOPERATIVE COMPLICATION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RISK ASSESSMENT; SURGICAL STRESS; TREATMENT INDICATION;

AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HEPATECTOMY; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; POSTOPERATIVE COMPLICATIONS; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 80051531048     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.21932     Document Type: Article

References (47)

1. Yamamoto J, Okada S, Shimada K, et al.: Treatment strategy for small hepatocellular carcinoma: Comparison of long-term results after percutaneous ethanol injection therapy and surgical resection. Hepatology 2001; 34: 707-714.
2. Poon RT, Fan ST,: Hepatectomy for hepatocellular carcinoma: Patient selection and postoperative outcome. Liver Transpl 2004; 10: 39-45.
3. Tung-Ping Poon R, Fan ST, Wong J,: Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma. Ann Surg 2000; 232: 10-24. (Pubitemid 30456545)
4. Shah SA, Cleary SP, Wei AC, et al.: Recurrence after liver resection for hepatocellular carcinoma: Risk factors, treatment, and outcomes. Surgery 2007; 141: 330-339. (Pubitemid 46371307)
5. Makuuchi M, Sano K,: The surgical approach to HCC: Our progress and results in Japan. Liver Transpl 2004; 10: S46-S52. (Pubitemid 38240100)
6. Tsujita E, Utsunomiya T, Ohta M, et al.: Outcome of repeat hepatectomy in patients with hepatocellular carcinoma aged 75 years and older. Surgery 2010; 147: 696-703.
7. Jing-Lin X, Sharma D, Bing-Hui Y, et al.: Analysis of the clinicopathological features of hepatocellular carcinoma in elderly patients. JNMA J Nepal Med Assoc 2008; 47: 132-135.
8. Huang J, Li BK, Chen GH, et al.: Long-term outcomes and prognostic factors of elderly patients with hepatocellular carcinoma undergoing hepatectomy. J Gastrointest Surg 2009; 13: 1627-1635.
9. Nagata T,: Macromolecular synthesis in the livers of aging mice as revealed by electron microscopic radioautography. Prog Histochem Cytochem 2010; 45: 1-79.
10. Levine WC, Mehta V, Landesberg G,: Anesthesia for the elderly: Selected topics. Curr Opin Anaesthesiol 2006; 19: 320-324. (Pubitemid 43864718)
11. Teh SH, Christein J, Donohue J, et al.: Hepatic resection of hepatocellular carcinoma in patients with cirrhosis: Model of End-Stage Liver Disease (MELD) score predicts perioperative mortality. J Gastrointest Surg 2005; 9: 1207-1215. (Pubitemid 41751112)
12. Luo KZ, Itamoto T, Amano H, et al.: Comparative study of the Japan Integrated Stage (JIS) and modified JIS score as a predictor of survival after hepatectomy for hepatocellular carcinoma. J Gastroenterol 2008; 43: 369-377. (Pubitemid 351958901)
13. El-Serag HB,: Epidemiology of hepatocellular carcinoma in USA. Hepatol Res 2007; 37: S88-S94.
14. Stroffolini T,: Etiological factor of hepatocellular carcinoma in Italy. Minerva Gastroenterol Dietol 2005; 51: 1-5. (Pubitemid 44251914)
15. Aldrighetti L, Arru M, Catena M, et al.: Liver resections in over-75-year-old patients: Surgical hazard or current practice? J Surg Oncol 2006; 93: 186-193. (Pubitemid 43381990)
16. Ferrero A, Viganà L, Polastri R, et al.: Hepatectomy as treatment of choice for hepatocellular carcinoma in elderly cirrhotic patients. World J Surg 2005; 29: 1101-1105. (Pubitemid 41618705)
17. Sgourakis G, Sotiropoulos GC, Bockhorn M, et al.: Major liver resections for primary liver malignancies in the elderly. Acta Chir Belg 2009; 109: 340-344.
18. Hanazaki K, Kajikawa S, Shimozawa N, et al.: Hepatic resection for hepatocellular carcinoma in the elderly. J Am Coll Surg 2001; 192: 38-46. (Pubitemid 32064096)
19. Kaibori M, Matsui K, Ishizaki M, et al.: Hepatic resection for hepatocellular carcinoma in the elderly. J Surg Oncol 2009; 99: 154-160.
20. Lok AS, Sterling RK, Everhart JE, et al.: Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma. Gastroenterology 2010; 138: 493-502.
21. Takasaki T, Kobayashi S, Suzuki S, et al.: Predetermining postoperative hepatic function for hepatectomies. Int Surg 1980; 65: 309-313. (Pubitemid 12155191)
22. Kubota K, Makuuchi M, Kusaka K, et al.: Measurement of liver volume and hepatic functional reserve as a guide to decision-making in resection surgery for hepatic tumors. Hepatology 1997; 26: 1176-1181. (Pubitemid 27509300)
23. Haga Y, Ikei S, Ogawa M,: Estimation of Physiologic Ability and Surgical Stress (E-PASS) as a new prediction scoring system for postoperative morbidity and mortality following elective gastrointestinal surgery. Surg Today 1999; 29: 219-225. (Pubitemid 29119837)
24. Haga Y, Wada Y, Takeuchi H, et al.: Estimation of physiologic ability and surgical stress (E-PASS) for a surgical audit in elective digestive surgery. Surgery 2004; 135: 586-594. (Pubitemid 38879341)
25. Knodell RG, Ishak KG, Black WC, et al.: Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981; 1: 431-435. (Pubitemid 12218164)
26. Liver Cancer Study Group of Japan: Clinical findings. In:, Makuuchi M, editor. General rules for the clinical and primary liver cancer, 2nd English edition. Tokyo: Kanehara Co., Ltd; 2003; pp 5-28.
27. Helmberger T, Dogan S, Straub G, et al.: Liver resection or combined chemoembolization and radiofrequency ablation improve survival in patients with hepatocellular carcinoma. Digestion 2007; 75: 104-112. (Pubitemid 47343961)
28. Yanaga K, Kanematsu T, Takenaka K, et al.: Hepatic resection for hepatocellular carcinoma in elderly patients. Am J Surg 1988; 155: 238-241. (Pubitemid 18070636)
29. Caratozzolo E, Massani M, Recordare A, et al.: Liver resection in elderly: Comparative study between younger and older than 70 years patients. Outcomes and implications for therapy. G Chir 2007; 28: 419-424.
30. Mirici-Cappa F, Gramenzi A, Santi V, et al.: Treatments for hepatocellular carcinoma in elderly patients are as effective as in younger patients: A 20-year multicentre experience. Gut 2010; 59: 387-396.
31. Koperna T, Kisser M, Schulz F,: Hepatic resection in the elderly. World J Surg 1998; 22: 406-412. (Pubitemid 28113530)
32. Banz VM, Studer P, Inderbitzin D, et al.: Validation of the estimation of physiologic ability and surgical stress (E-PASS) score in liver surgery. World J Surg 2009; 33: 1259-1265.
33. Teriokhin AT, Budilova EV, Thomas F, et al.: Worldwide variation in life-span sexual dimorphism and sex-specific environmental mortality rates. Hum Biol 2004; 76: 623-641. (Pubitemid 40192850)
34. Knaus WA, Draper EA, Wagner DP, et al.: APACHE II: A severity of disease classification system. Crit Care Med 1985; 13: 818-829. (Pubitemid 15250137)
35. Copeland GP, Jones D, Walters M,: POSSUM: A scoring system for surgical audit. Br J Surg 1991; 78: 355-360.
36. Hashimoto D, Takamori H, Sakamoto Y, et al.: Is an estimation of physiologic ability and surgical stress able to predict operative morbidity after pancreaticoduodenectomy? J Hepatobiliary Pancreat Sci 2010; 17: 132-138.
37. Hashimoto D, Takamori H, Sakamoto Y, et al.: Can the physiologic ability and surgical stress (E-PASS) scoring system predict operative morbidity after distal pancreatectomy? Surg Today 2010; 40: 632-637.
38. Yamashita S, Haga Y, Nemoto E, et al.: Comparison of surgical outcome using the prediction scoring system of E-PASS for thoracic surgery. Jpn J Thorac Cardiovasc Surg 2006; 54: 391-395. (Pubitemid 44623100)
39. Kaneko H,: Laparoscopic hepatectomy: Indications and outcomes. J Hepatobiliary Pancreat Surg 2005; 12: 438-443. (Pubitemid 43124435)
40. Hattori H, Kamiya J, Shimada H, et al.: Assessment of the risk of postoperative delirium in elderly patients using E-PASS and the NEECHAM Confusion Scale. Int J Geriatr Psychiatry 2009; 24: 1304-1310.
41. Hirose J, Mizuta H, Ide J, et al.: Evaluation of estimation of physiologic ability and surgical stress (E-PASS) to predict the postoperative risk for hip fracture in elder patients. Arch Orthop Trauma Surg 2008; 128: 1447-1452.
42. Nanashima A, Tobinaga S, Abo T, et al.: Usefulness of the combination procedure of crash clamping and vessel sealing for hepatic resection. J Surg Oncol 2010; 102: 179-183.
43. Nanashima A, Sumida Y, Abo T, et al.: Usefulness and application of the liver hanging maneuver for anatomical liver resections. World J Surg 2008; 32: 2070-2076.
44. Nanashima A, Abo T, Sumida Y, et al.: Clinicopathological characteristics of patients with hepatocellular carcinoma after hepatectomy: Relationship with status of viral hepatitis. J Surg Oncol 2007; 96: 487-492. (Pubitemid 350044392)
45. Shimada M, Rikimaru T, Hamatsu T, et al.: The role of macroscopic classification in nodular-type hepatocellular carcinoma. Am J Surg 2001; 182: 177-182. (Pubitemid 32907357)
46. Nanashima A, Tanaka K, Yamaguchi H, et al.: Fibrosis and inflammatory activity in noncancerous tissue and mitotic index of cancer tissue in patients with hepatocellular carcinoma: Relationship to clinicopathological factors and prognosis after hepatic resection. Dig Dis Sci 2003; 48: 1517-1522. (Pubitemid 36936687)
47. Nagasue N,: Liver resection for hepatocellular carcinoma: Indications, techniques, complications, and prognostic factors. J Hepatobiliary Pancreat Surg 1998; 5: 7-13. (Pubitemid 128662550)