Current assessment of sperm DNA integrity

Archives of Andrology

Volumn 53, Issue 5, 2007, Pages 239-247

  Marchesi, Dennis E ^a   Feng, Huai L ^a   Hershlag, Avner ^a  

^a NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

Male infertility; nDNA; Sperm assessment; Sperm chromatin

Indexed keywords

DNA;

CHROMATIN STRUCTURE; COMET ASSAY; COST BENEFIT ANALYSIS; DNA FRAGMENTATION; FERTILIZATION; FLOW CYTOMETRY; NICK END LABELING; PRIORITY JOURNAL; REVIEW; SEMEN ANALYSIS; CHEMISTRY; CHROMATIN; GENETICS; HUMAN; MALE; METABOLISM; SPERMATOZOON;

CHROMATIN; COMET ASSAY; DNA; FLOW CYTOMETRY; HUMANS; IN SITU NICK-END LABELING; MALE; SPERMATOZOA;

EID: 80051492356     PISSN: 01485016     EISSN: 15210375     Source Type: Journal    
DOI: 10.1080/01485010701569858     Document Type: Review

References (54)

1. Agarwal, A. and Allamaneni, S. S. R. (2005) Sperm DNA damage assessment: A test whose time has come. Fertil Steril 84:850-853.
2. Agarwal, A. and Said, T. M. (2003) Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update 9:331-345.
3. Ainsworth, C., Nixon, B. and Aitken, R. J. (2005) Development of a novel electrophoretic system for the isolation of human spermatozoa. Hum Reprod 20:2261-2270.
4. Ankem, M. K., Mayer, E., Ward, W. S., Cummings, K. B. and Barone, J. G. (2002) Novel assay for determining DNA organization in human spermatozoa: Implications for male factor infertility. Urology 59:575-578.
5. Aziz, N., Said, T., Paasch, U. and Agarwal, A. (2007) The relationship between human sperm apoptosis, morphology and the sperm deformity index. Hum Reprod. Advance Access February 15, 2007:1-7.
6. Benchaib, M., Braun, V., Lornage, J., Hadj, S., Salle, B., Lejeune, H. and Guerin, J. F. (2003) Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique. Hum Reprod 18:1023-1028.
7. Boe-Hansen, G. B., Fedder, J., Ersboll, A. K. and Christensen, P. (2006) The sperm chromatin structure assay as a diagnostic tool in the human fertility clinic. Hum Reprod 21:1576-1582.
8. Bungum, M., Humaidan, P., Axmon, A., Spano, M., Bungum, L., Erenpreiss, J. and Giwercman, A. (2007) Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome. Hum Reprod 22:174-179.
9. Bungum, M., Humaidan, P., Spano, M., Jepson, K., Bungum, L. and Giwercman, A. (2004) The predictive value of sperm chromatin structure assay (SCSA) parameters and the outcome of intrauterine insemination, IVF and ICSI. Hum Reprod 19:1401-1408.
10. Emiliani, S., Van den Bergh, M., Vannin, A. S., Biramane, J., Verdoot, M. and Englert, Y. (2001) Evidence of reduced single-stranded testicular sperm DNA from obstructive azoospermic men after 3 days of in-vitro culture. Hum Reprod 16:1200-1203.
11. Erenpreiss, J., Bars, J., Lipatnikova, V., Erenpreisa, J. and Zalkalns, J. (2001) Comparative study of cytochemical tests for sperm chromatin integrity. J Androl 22:45-53.
12. Erenpreisa, J., Erenpreiss, J., Freivalds, T., Slaidina, M., Krampe, R., Butikova, J., Ivanoc, A. and Pjanova, D. (2003) Toluidine blue test for sperm DNA integrity and elaboration of image cytometry algorithm. Cytometry Part A 52A:19-27.
13. Erenpreiss, J., Jepson, K., Giwercman, A., Tsarev, I., Erenpreisa, J. and Spano, M. (2004) Toluidine blue cytometry test for sperm DNA conformation: Comparison with the flow cytometric sperm chromatin structure and TUNEL assays. Hum Reprod 19:2277-2282.
14. Evenson, D. P., Jost, L. K., Baer, R. K., Turner, T. W. and Schrader, S. M. (1991) Individuality of DNA denaturation patterns in human sperm as measured by the sperm chromatin structure assay. Reprod Tox 5:115-125.
15. Evenson, D. and Wixon, R. (2006) Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay. Reprod BioMed Online 12:466-472.
16. Fernandez, J. L., Muriel, L., Goyanes, V., Segrelles, E., Gosalvez, J., Enciso, M., LaFromboise, M. and De Jonge, C. (2005) Simple determination of human sperm DNA with an improved sperm chromatin dispersion test. Fertil Steril 84:833-842.
17. Fernandez, J. L., Muriel, L., Rivero, M. T., Goyanes, V., Vazquez, R. and Alvarez, J. G. (2003) The sperm chromatin dispersion test: A simple method for the determination of sperm DNA fragmentation. J. Androl 24:59-66.
18. Gavriele, Y., Sherman, Y. and Ben-Sasson, S. A. (1992) Identification of programmed cell death in-situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol 119:493-501.
19. Grunewald, S., Miska, W., Miska, G., Rasch, M., Reinhardt, M., Glander, H.-J. and Paasch, U. (2007) Molecular glass wool filtration as a new tool for sperm preparation. Hum Reprod. Advance Access. March 2, 2007:1-8.
20. Huszar, G., Celik-Ozenci, C., Cayli, S., Zavaczki, Z., Hansch, E. and Vigue, L. (2003) Hyaluronic acid binding by human sperm indicates cellular maturity, viability, and unreacted acrosomal status. Fertil Steril 79:S1616-S1624.
21. Jakab, A., Sakkas, D., Delpiano, E., Cayli, S., Kovanci, E., Ward, D., Ravelli, A. and Huszar, G. (2005) Intracytoplasmic sperm injection: A novel selection method for sperm with normal frequency of chromosomal aneuploidies. Fertil Steril 84:1665-1673.
22. Kramer, J. A. and Krawetz, S. A. (1996) Nuclear matrix interactions within the sperm genome. J. BiolChem 271:11619-11622.
23. Kruger, T. F., Acosta, A. A., Simmons, K. F., Swanson, R. J., Matta, J. F. and Oehninger, S. (1988) Predictive value of abnormal sperm morphology in in vitro fertilization. Fertil Steril 49:112-117.
24. Larson-Cook, K. L., Brannian, J. D., Hansen, K. A., Kasperson, K. M., Aamold, E. T. and Evenson, D. P. (2003) Relationship between the outcomes of assisted reproductive techniques and sperm DNA fragmentation as measured by the sperm chromatin structure assay. Fertil Steril 80:895-902.
25. Lewis, S. E. M. and Aitken, R. J. (2005) DNA damage to spermatozoa has impacts on fertilization and pregnancy. Cell Tissue Res 322:33-41.
26. Martins, C. F., Dodo, M. N., Bao, S. N. and Rumpf, R. (2007) The use of the acridine orange test and the TUNEL assay to assess the integrity of freeze-dried bovine spermatozoa DNA. Genet Molec Res 6:94-104. http://www.funpecrp.com.br/gmr/
27. Muriel, L., Meseguer, M., Fernandez, J. L., Alvarez, J., Remohi, J., Pellicer, A. and Garrido, N. (2006) Value of the sperm chromatin dispersion test in predicting pregnancy outcome in intrauterine insemination: A blind prospective study. Hum Reprod 21:738-744.
28. Paasch, U., Grunewald, S., Fitzl, G. and Glander, H-J. (2003) Deterioration of plasma membrane is associated with activated caspases in human spermatozoa. J Androl 24:246-252.
29. Payne, T. F., Raburn, D. J., Couchman, G. M., Price, T. M., Jamison, M. G. and Walker, D. K. (2005) Redefining the relationship between sperm deoxyribonucleic acid fragmentation as measured by the sperm chromatin structure assay and outcomes of assisted reproductive techniques. Fertil Steril 84:356-364.
30. Ramos, L. and Wetzels, A. M. M. (2001) Low rates of DNA fragmentation in selected motile human spermatozoa assessed by the TUNEL assay. Hum Reprod 16:1703-1707.
31. Said, T. M., Grunewald, S., Paasch, U., Glander, H.-J., Baumann, T., Kriegel, C., Li, L. and Agarwal, A. (2005b) Advantage of combining magnetic cell separation with sperm preparation techniques. Reprod BioMed Online 10:740-746.
32. Said, T. M., Grunewald, S., Paasch, U., Rasch, M., Agarwal, A. and Glander, H.-J. (2005a) Effects of magnetic-activated cell sorting on sperm motility and cryosurvival rates. Fertil Steril 83:1442-1446.
33. Sakkas, D., Mariethoz, E., Manicardi, G., Bizzaro, D., Bianchi, P. G. and Bianchi, U. (1999) Origin of DNA damage in ejaculated human spermatozoa. Rev Reprod 4:31-37.
34. Sakkas, D., Moffatt, O., Manicardi, G. C., Mariethoz, E., Tazozzi, N. and Bizzaro, D. (2002) Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis. Biol Reprod 66:1061-1067.
35. Saleh, R. A., Agarwal, A., Nelson, D. R., Nada, E. A., El-Tonsy, M. H., Alvarez, J. G., Thomas, A. J. and Sharma, R. K. (2002) Increased sperm nuclear DNA damage in normozoospernic infertile men: a prospective study. Fertil Steril 78:313-318.
36. Schlegel, P. N. and Paduch, D. A. (2005) Yet another test of sperm chromatin structure. Fertil Steril 84:854-859.
37. Seli, E., Gardner, D. K., Schoolcraft, W. B., Moffatt, O. and Sakkas, D. (2004) Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization. Fertil Steril 82:378-383.
38. Shafik, A., Shafik, A. A., Shafik, I. and El Sibai, O. (2006) Sperm DNA fragmentation. Arch Androl 52:197-208.
39. Sharma, R. K., Said, T. and Agarwal, A. (2004) Sperm DNA damage and its clinical relevance in assessing reproductive outcome. Asian J Androl 6:139-148.
40. Singh, N. P., McCoy, M. T., Tice, R. R. and Schneider E. L. (1988) A simple technique for quantification of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191.
41. Spano, M., Seli, E., Bizzaro, D., Manicardi, G. C. and Sakkas, D. (2005) The significance of sperm nuclear DNA strand breaks on reproductive outcome. Curr Opin Obstet Gynecol 17:255-260.
42. Steele, E. K., McClure, N., Maxwell, R. J. and Lewis, S. E. M. (1999) A comparison of DNA damage in testicular and proximal epididymal spermatozoa in obstructive azoospermia. Mol Hum Reprod 5:831-835.
43. Tesarik, J., Mendoza-Tesarik, R. and Mendoza, C. (2006) Sperm nuclear DNA damage: Update on the mechanism, diagnosis and treatment. Reprod BioMed Online 12:715-721.
44. Trisini, A. T., Singh, N. P., Duty, S. M. and Hauser, R. (2004) Relationship between human semen parameters and deoxyribonucleic acid damage assessed by the neutral comet assay. Fertil Steril 82:1623-1632.
45. Van Dyk, Q., Lanzendorf, S., Kolm, P., Hodgen, G. D. and Mahony, M. C. (2000) Incidence of aneuploid spermatozoa from subfertile men: Selected with motility versus hemizona-bound. Hum Reprod 15:1529-1536.
46. Varum, S., Bento, C., Sousa, A. P. M., Gomes-Santos, C. S. S., Henriques, P., Almeida-Santos, T., Teodosio, C., Paiva, A. and Ramalho-Santos, J. (2007) Characterization of human sperm populations using conventional parameters, surface ubiquitination, and apoptotic markers. Fertil Steril 87:572-583.
47. Virro, M. R., Larson-Cook, K. L. and Evenson, D. P. (2004) Sperm chromatin structure assay (SCSA) parameters are related to fertilization, blastocyst development, and ongoing pregnancy in in vitro fertilization and intracytoplasmic injection cycles. Fertil Steril 81:1289-1295.
48. Wang, X., Sharma, R. K., Sikka, S. C., Thomas, A. J., Falcone, T. and Agarwal, A. (2003) Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility. Fertil Steril 80:531-535.
49. Ward, W. S., Kimura, Y. and Yanagimachi, R. (1999) An intact sperm nuclear matrix may be necessary for the mouse paternal genome to participate in embryonic development. Biol Reprod 14:702-706.
50. Weng, S. L., Taylor, S. L., Morshedi, M., Schuffner, A., Duran, E. K., Beebe, S. and Oehninger, S. (2002) Caspase activity and apoptotic markers in ejaculated human sperm. Mol Hum Reprod 8:984-991.
51. World Health Organization (1980) WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 1st ed. Cambridge, UK: Cambridge University Press.
52. Ye, H., Huang, G., Gao, Y. and Liu, D. Y. (2006) Relationship between human sperm-hyaluronan binding assay and fertilization rate in conventional in vitro fertilization. Hum Reprod 21:1545-1550.
53. Zini, A., Bielecki, R., Phang, D. and Zenzes, M. T. (2001) Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men. Fertil Steril 75:674-677.
54. Zini, A. and Libman, J. (2006) Sperm DNA damage: Clinical significance in the era of assisted reproduction. CMAJ 175:495-500.