The sperm chromatin structure assay as a diagnostic tool in the human fertility clinic

Human Reproduction

Volumn 21, Issue 6, 2006, Pages 1576-1582

  Boe Hansen, Gry Brandt ^a   Fedder, Jens ^b   Ersbøll, Annette Kjær ^a   Christensen, Preben ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b HORSENS REGIONAL HOSPITAL   (Denmark)

Author keywords

Male infertility; Morphology; Pregnancy; Sperm DNA fragmentation; Spermatozoa

Indexed keywords

DNA FRAGMENT;

ADULT; ARTICLE; CELL ASSAY; CELL STRUCTURE; CHROMATIN STRUCTURE; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; EMBRYO; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; GESTATIONAL AGE; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTRACYTOPLASMIC SPERM INJECTION; INTRAUTERINE INSEMINATION; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; NIDATION; OUTCOME ASSESSMENT; PREGNANCY OUTCOME; PROGNOSIS; SPERMATOZOON; STRUCTURE ANALYSIS;

EID: 33749019346     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/del019     Document Type: Article

References (33)

1. Ahmadi A and Ng SC (1999) Fertilizing ability of DNA-damaged spermatozoa. J Exp Zool 284,696-704.
2. Aitken RJ, Koopman P and Lewis SE (2004) Seeds of concern. Nature 432,48-52.
3. Ballachey BE, Evenson DP and Saacke RG (1988) The sperm chromatin structure assay. Relationship with alternate tests of semen quality and heterospermic performance of bulls. J Androl 9,109-115.
4. Boe-Hansen GB, Ersbøll AK and Christensen P (2005) Variability and laboratory factors affecting the sperm chromatin structure assay (SCSA) in human semen. J Androl 26,360-368.
5. Bungum M, Humaidan P, Spano M, Jepson K, Bungum L and Giwercman A (2004) The predictive value of sperm chromatin structure assay (SCSA) parameters for the outcome of intrauterine insemination, IVF and ICSI. Hum Reprod 19,1401-1408.
6. Check JH, Graziano V, Cohen R, Krotec J and Check ML (2005) Effect of an abnormal sperm chromatin structural assay (SCSA) on pregnancy outcome following (IVF) with ICSI in previous IVF failures. Arch Androl 51,121-124.
7. Erenpreiss J, Jepson K, Giwercman A, Tsarev I, Erenpreisa J and Spano M (2004) Toluidine blue cytometry test for sperm DNA conformation: comparison with the flow cytometric sperm chromatin structure and TUNEL assays. Hum Reprod 19,2277-2282.
8. Evenson DP (1999) Loss of livestock breeding efficiency due to uncompensable sperm nuclear defects. Reprod Fertil Dev 11,1-15.
9. Evenson DP and Jost LK (2000) Sperm chromatin structure assay for fertility assessment. In Robinson P (ed.) Current Protocols in Cytometry. John Wiley & Sons, New York.
10. Evenson DP, Darzynkiewicz Z and Melamed MR (1980) Relation of mammalian sperm chromatin heterogeneity to fertility. Science 210,1131-1133.
11. Evenson DP, Thompson L and Jost L (1994) Flow cytometric evaluation of boar semen by the sperm chromatin structure assay as related to cryopreservation and fertility. Theriogenology 41,637-651.
12. Evenson DP, Jost LK, Marshall D, Zinaman MJ, Clegg E, Purvis K, de Angelis P and Claussen OP (1999) Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic. Hum Reprod 14,1039-1049.
13. Evenson DP, Larson KL and Jost LK (2002) Sperm chromatin structure assay: Its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques. J Androl 23,25-43.
14. Fraga CG, Motchnik PA, Wyrobek AJ, Rempel DM and Ames BN (1996) Smoking and low antioxidant levels increase oxidative damage to sperm DNA. Mutat Res 351,199-203.
15. Gandini L, Lombardo F, Paoli D, Caruso F, Eleuteri P, Leter G, Ciriminna R, Culasso F, Dondero F, Lenzi A et al. (2004) Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage. Hum Reprod 19,1409-1417.
16. Giwercman A, Richthoff J, Hjollund H, Bonde JP, Jepson K, Frohm B and Spano M (2003) Correlation between sperm motility and sperm chromatin structure assay parameters. Fertil Steril 80,1404-1412.
17. Golan R, Shochat L, Weissenberg R, Soffer Y, Marcus Z, Oschry Y and Lewin LM (1997) Evaluation of chromatin condensation in human spermatozoa: A flow cytometric assay using acridine orange staining. Mol Hum Reprod 3,47-54.
18. Greco E, Scarselli F, Iacobelli M, Rienzi L, Ubaldi F, Ferrero S, Franco G, Anniballo N, Mendoza C and Tesarik J (2005) Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa. Hum Reprod 20,226-230.
19. Høst E, Lindenberg S and Smidt-Jensen S (2000) The role of DNA strand breaks in human spermatozoa used for IVF and ICSI. Acta Obstet Gynecol Scand 79,559-563.
20. Ji BT, Shu XO, Linet MS, Zheng W, Wacholder S, Gao YT, Ying DM and Jin F (1997) Paternal cigarette smoking and the risk of childhood cancer among offspring of nonsmoking mothers. J Natl Cancer Inst 89,238-244.
21. Kruger TF, Acosta AA, Simmons KF, Swanson RJ, Matta JF, Veeck LL, Morshedi M and Brugo S (1987) New method of evaluating sperm morphology with predictive value for human in vitro fertilization. Urology 30,248-251.
22. Kruger TF, Franker DR and Menkveld R (2000) Strict 1-2-3 A self teaching program for strict sperm morphology. Pamphlet.
23. Larson KL, Brannian JD, Timm BK, Jost LK and Evenson DP (1999) Density gradient centrifugation and glass wool filtration of semen remove spermatozoa with damaged chromatin structure. Hum Reprod 14,2015-2019.
24. Larson KL, DeJonge CJ, Barnes AM, Jost LK and Evenson DP (2000) Sperm chromatin structure assay parameters as predictors of failed pregnancy following assisted reproductive techniques. Hum Reprod 15,1717-1722.
25. Larson-Cook KL, Brannian JD, Hansen KA, Kasperson KM, Aamold ET and Evenson DP (2003) Relationship between the outcomes of assisted reproductive techniques and sperm DNA fragmentation as measured by the sperm chromatin structure assay. Fertil Steril 80,895-902.
26. Saleh RA, Agarwal A, Nada EA, El Tonsy ME, Sharma RK, Meyer A, Nelson DR and Thomas AJ (2003) Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility. Fertil Steril 79(Suppl. 3),1597-1605.
27. Seli E and Sakkas D (2005) Spermatozoal nuclear determination of reproductive outcome: Implications for ART. Hum Reprod Update 11,337-349.
28. Sorahan T, Prior P, Lancashire RJ, Faux SP, Hulten MA, Peck IM and Stewart AM (1997) Childhood cancer and parental use of tobacco: Deaths from 1971 to 1976. Br J Cancer 76,1525-1531.
29. Spano M, Kolstad H, Larsen SB, Cordelli E, Leter G, Giwercman A and Bonde JP (1999) Flow cytometric sperm chromatin structure assay as an independent descriptor of human semen quality. Scand J Work Environ Health 25(Suppl. 1),28-30.
30. Spano M, Bonde JP, Hjollund HI, Kolstad HA, Cordelli E and Leter G (2000) Sperm chromatin damage impairs human fertility. The Danish First Pregnancy Planner Study Team. Fertil Steril 73,43-50.
31. Sun JG, Jurisicova A and Casper RF (1997) Detection of deoxyribonucleic acid fragmentation in human sperm: Correlation with fertilization in vitro. Biol Reprod 56,602-607.
32. Virro MR, Larson-Cook KL and Evenson DP (2004) Sperm chromatin structure assay (scsa (R) parameters are related to fertilization, blastocyst development, and ongoing pregnancy in in vitro fertilization and intracytoplasmic sperm injection cycles. Fertil Steril 81,1289-1295.
33. World Health Organization (1999) WHO laboratory manual for examination of human semen and sperm-cervical mucus interaction, 4th edn. Cambridge University Press, Cambridge, United Kingdom.