메뉴 건너뛰기




Volumn 21, Issue 2, 2011, Pages 231-244

Genome-Wide RNAi Screens Identify Genes Required for Ricin and PE Intoxications

Author keywords

[No Author keywords available]

Indexed keywords

PSEUDOMONAS EXOTOXIN; RICIN; SHIGA TOXIN; SYNTAXIN 16;

EID: 80051469646     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2011.06.014     Document Type: Article
Times cited : (60)

References (58)
  • 1
    • 34249089996 scopus 로고    scopus 로고
    • Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins
    • Amessou M., Fradagrada A., Falguières T., Lord J.M., Smith D.C., Roberts L.M., Lamaze C., Johannes L. Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins. J. Cell Sci. 2007, 120:1457-1468.
    • (2007) J. Cell Sci. , vol.120 , pp. 1457-1468
    • Amessou, M.1    Fradagrada, A.2    Falguières, T.3    Lord, J.M.4    Smith, D.C.5    Roberts, L.M.6    Lamaze, C.7    Johannes, L.8
  • 8
    • 67949106610 scopus 로고    scopus 로고
    • Substrate-specific mediators of ER associated degradation (ERAD)
    • Brodsky J.L., Wojcikiewicz R.J.H. Substrate-specific mediators of ER associated degradation (ERAD). Curr. Opin. Cell Biol. 2009, 21:516-521.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 516-521
    • Brodsky, J.L.1    Wojcikiewicz, R.J.H.2
  • 9
    • 0028242142 scopus 로고
    • Functional role of a consensus peptide which is common to alpha-, beta-, and gamma-tubulin, to actin and centractin, to phytochrome A, and to the TCP1 alpha chaperonin protein
    • Burns R.G., Surridge C.D. Functional role of a consensus peptide which is common to alpha-, beta-, and gamma-tubulin, to actin and centractin, to phytochrome A, and to the TCP1 alpha chaperonin protein. FEBS Lett. 1994, 347:105-111.
    • (1994) FEBS Lett. , vol.347 , pp. 105-111
    • Burns, R.G.1    Surridge, C.D.2
  • 10
    • 70349994670 scopus 로고    scopus 로고
    • A yeast killer toxin screen provides insights into a/b toxin entry, trafficking, and killing mechanisms
    • Carroll S.Y., Stirling P.C., Stimpson H.E.M., Giesselmann E., Schmitt M.J., Drubin D.G. A yeast killer toxin screen provides insights into a/b toxin entry, trafficking, and killing mechanisms. Dev. Cell 2009, 17:552-560.
    • (2009) Dev. Cell , vol.17 , pp. 552-560
    • Carroll, S.Y.1    Stirling, P.C.2    Stimpson, H.E.M.3    Giesselmann, E.4    Schmitt, M.J.5    Drubin, D.G.6
  • 12
    • 33845905221 scopus 로고    scopus 로고
    • Dynein is required for receptor sorting and the morphogenesis of early endosomes
    • Driskell O.J., Mironov A., Allan V.J., Woodman P.G. Dynein is required for receptor sorting and the morphogenesis of early endosomes. Nat. Cell Biol. 2007, 9:113-120.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 113-120
    • Driskell, O.J.1    Mironov, A.2    Allan, V.J.3    Woodman, P.G.4
  • 13
    • 0037059752 scopus 로고    scopus 로고
    • The human EMAP-like protein-70 (ELP70) is a microtubule destabilizer that localizes to the mitotic apparatus
    • Eichenmuller B., Everley P., Palange J., Lepley D., Suprenant K.A. The human EMAP-like protein-70 (ELP70) is a microtubule destabilizer that localizes to the mitotic apparatus. J. Biol. Chem. 2002, 277:1301-1309.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1301-1309
    • Eichenmuller, B.1    Everley, P.2    Palange, J.3    Lepley, D.4    Suprenant, K.A.5
  • 14
    • 0033922714 scopus 로고    scopus 로고
    • Penetration of protein toxins into cells
    • Falnes P.O., Sandvig K. Penetration of protein toxins into cells. Curr. Opin. Cell Biol. 2000, 12:407-413.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 407-413
    • Falnes, P.O.1    Sandvig, K.2
  • 15
    • 38349014268 scopus 로고    scopus 로고
    • A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells
    • Ganley I.G., Espinosa E., Pfeffer S.R. A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells. J. Cell Biol. 2008, 180:159-172.
    • (2008) J. Cell Biol. , vol.180 , pp. 159-172
    • Ganley, I.G.1    Espinosa, E.2    Pfeffer, S.R.3
  • 16
    • 0035105678 scopus 로고    scopus 로고
    • Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
    • Garred Ø., Rodal S.K., van Deurs B., Sandvig K. Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase. Traffic 2001, 2:26-36.
    • (2001) Traffic , vol.2 , pp. 26-36
    • Garred, Ø.1    Rodal, S.K.2    van Deurs, B.3    Sandvig, K.4
  • 18
    • 0033634889 scopus 로고    scopus 로고
    • Endosome to Golgi transport of ricin is regulated by cholesterol
    • Grimmer S., Iversen T.G., van Deurs B., Sandvig K. Endosome to Golgi transport of ricin is regulated by cholesterol. Mol. Biol. Cell 2000, 11:4205-4216.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 4205-4216
    • Grimmer, S.1    Iversen, T.G.2    van Deurs, B.3    Sandvig, K.4
  • 19
    • 4344610200 scopus 로고    scopus 로고
    • Cytotoxic ribosome-inactivating lectins from plants
    • Hartley M.R., Lord J.M. Cytotoxic ribosome-inactivating lectins from plants. Biochim. Biophys. Acta 2004, 1701:1-14.
    • (2004) Biochim. Biophys. Acta , vol.1701 , pp. 1-14
    • Hartley, M.R.1    Lord, J.M.2
  • 20
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4:44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 22
    • 30744471419 scopus 로고    scopus 로고
    • Protein toxins: intracellular trafficking for targeted therapy
    • Johannes L., Decaudin D. Protein toxins: intracellular trafficking for targeted therapy. Gene Ther. 2005, 12:1360-1368.
    • (2005) Gene Ther. , vol.12 , pp. 1360-1368
    • Johannes, L.1    Decaudin, D.2
  • 23
    • 57749196733 scopus 로고    scopus 로고
    • Tracing the retrograde route in protein trafficking
    • Johannes L., Popoff V. Tracing the retrograde route in protein trafficking. Cell 2008, 135:1175-1187.
    • (2008) Cell , vol.135 , pp. 1175-1187
    • Johannes, L.1    Popoff, V.2
  • 24
    • 75749125021 scopus 로고    scopus 로고
    • Shiga toxins-from cell biology to biomedical applications
    • Johannes L., Römer W. Shiga toxins-from cell biology to biomedical applications. Nat. Rev. Microbiol. 2010, 8:105-116.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 105-116
    • Johannes, L.1    Römer, W.2
  • 25
    • 70349581497 scopus 로고    scopus 로고
    • Cytoscape: a community-based framework for network modeling
    • Killcoyne S., Carter G.W., Smith J., Boyle J. Cytoscape: a community-based framework for network modeling. Methods Mol. Biol. 2009, 563:219-239.
    • (2009) Methods Mol. Biol. , vol.563 , pp. 219-239
    • Killcoyne, S.1    Carter, G.W.2    Smith, J.3    Boyle, J.4
  • 27
    • 77952934647 scopus 로고    scopus 로고
    • Lipids and cholesterol as regulators of traffic in the endomembrane system
    • Lippincott-Schwartz J., Phair R.D. Lipids and cholesterol as regulators of traffic in the endomembrane system. Annu. Rev. Biophys. 2010, 39:559-578.
    • (2010) Annu. Rev. Biophys. , vol.39 , pp. 559-578
    • Lippincott-Schwartz, J.1    Phair, R.D.2
  • 28
    • 31944450533 scopus 로고    scopus 로고
    • Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity
    • Low S.H., Vasanji A., Nanduri J., He M., Sharma N., Koo M., Drazba J., Weimbs T. Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity. Mol. Biol. Cell 2006, 17:977-989.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 977-989
    • Low, S.H.1    Vasanji, A.2    Nanduri, J.3    He, M.4    Sharma, N.5    Koo, M.6    Drazba, J.7    Weimbs, T.8
  • 29
    • 0033529564 scopus 로고    scopus 로고
    • Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13
    • McBride H.M., Rybin V., Murphy C., Giner A., Teasdale R., Zerial M. Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13. Cell 1999, 98:377-386.
    • (1999) Cell , vol.98 , pp. 377-386
    • McBride, H.M.1    Rybin, V.2    Murphy, C.3    Giner, A.4    Teasdale, R.5    Zerial, M.6
  • 30
    • 20444381680 scopus 로고    scopus 로고
    • Acid-triggered membrane insertion of Pseudomonas exotoxin A involves an original mechanism based on pH-regulated tryptophan exposure
    • Méré J., Morlon-Guyot J., Bonhoure A., Chiche L., Beaumelle B. Acid-triggered membrane insertion of Pseudomonas exotoxin A involves an original mechanism based on pH-regulated tryptophan exposure. J. Biol. Chem. 2005, 280:21194-21201.
    • (2005) J. Biol. Chem. , vol.280 , pp. 21194-21201
    • Méré, J.1    Morlon-Guyot, J.2    Bonhoure, A.3    Chiche, L.4    Beaumelle, B.5
  • 31
    • 0028920154 scopus 로고
    • The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack
    • Miesenböck G., Rothman J.E. The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack. J. Cell Biol. 1995, 129:309-319.
    • (1995) J. Cell Biol. , vol.129 , pp. 309-319
    • Miesenböck, G.1    Rothman, J.E.2
  • 32
    • 4444229456 scopus 로고    scopus 로고
    • Exportin 7 defines a novel general nuclear export pathway
    • Mingot J.-M., Bohnsack M.T., Jäkle U., Görlich D. Exportin 7 defines a novel general nuclear export pathway. EMBO J. 2004, 23:3227-3236.
    • (2004) EMBO J. , vol.23 , pp. 3227-3236
    • Mingot, J.-M.1    Bohnsack, M.T.2    Jäkle, U.3    Görlich, D.4
  • 33
    • 0022005540 scopus 로고
    • Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin
    • Moya M., Dautry-Varsat A., Goud B., Louvard D., Boquet P. Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin. J. Cell Biol. 1985, 101:548-559.
    • (1985) J. Cell Biol. , vol.101 , pp. 548-559
    • Moya, M.1    Dautry-Varsat, A.2    Goud, B.3    Louvard, D.4    Boquet, P.5
  • 34
    • 12544260025 scopus 로고    scopus 로고
    • Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone
    • Niemeier A., Kassem M., Toedter K., Wendt D., Ruether W., Beisiegel U., Heeren J. Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone. J. Bone Miner. Res. 2005, 20:283-293.
    • (2005) J. Bone Miner. Res. , vol.20 , pp. 283-293
    • Niemeier, A.1    Kassem, M.2    Toedter, K.3    Wendt, D.4    Ruether, W.5    Beisiegel, U.6    Heeren, J.7
  • 35
    • 0028229595 scopus 로고
    • Effect of lovastatin on the cytotoxicity of ricin, modeccin, Pseudomonas toxin, and diphtheria toxin in brefeldin A-sensitive and -resistant cell lines
    • Oda T., Wu H.C. Effect of lovastatin on the cytotoxicity of ricin, modeccin, Pseudomonas toxin, and diphtheria toxin in brefeldin A-sensitive and -resistant cell lines. Exp. Cell Res. 1994, 212:329-337.
    • (1994) Exp. Cell Res. , vol.212 , pp. 329-337
    • Oda, T.1    Wu, H.C.2
  • 36
    • 31944450850 scopus 로고    scopus 로고
    • Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
    • Oda Y., Okada T., Yoshida H., Kaufman R.J., Nagata K., Mori K. Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J. Cell Biol. 2006, 172:383-393.
    • (2006) J. Cell Biol. , vol.172 , pp. 383-393
    • Oda, Y.1    Okada, T.2    Yoshida, H.3    Kaufman, R.J.4    Nagata, K.5    Mori, K.6
  • 37
    • 0035809210 scopus 로고    scopus 로고
    • Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex
    • Otte S., Belden W.J., Heidtman M., Liu J., Jensen O.N., Barlowe C. Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J. Cell Biol. 2001, 152:503-518.
    • (2001) J. Cell Biol. , vol.152 , pp. 503-518
    • Otte, S.1    Belden, W.J.2    Heidtman, M.3    Liu, J.4    Jensen, O.N.5    Barlowe, C.6
  • 39
    • 77954056447 scopus 로고    scopus 로고
    • A direct phenotypic comparison of siRNA pools and multiple individual duplexes in a functional assay
    • Parsons B.D., Schindler A., Evans D.H., Foley E. A direct phenotypic comparison of siRNA pools and multiple individual duplexes in a functional assay. PLoS ONE 2009, 4:e8471.
    • (2009) PLoS ONE , vol.4
    • Parsons, B.D.1    Schindler, A.2    Evans, D.H.3    Foley, E.4
  • 40
    • 39749142542 scopus 로고    scopus 로고
    • Retrograde traffic in the biosynthetic-secretory route
    • Pavelka M., Neumüller J., Ellinger A. Retrograde traffic in the biosynthetic-secretory route. Histochem. Cell Biol. 2008, 129:277-288.
    • (2008) Histochem. Cell Biol. , vol.129 , pp. 277-288
    • Pavelka, M.1    Neumüller, J.2    Ellinger, A.3
  • 41
    • 70349319578 scopus 로고    scopus 로고
    • Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network
    • Pérez-Victoria F.J., Bonifacino J.S. Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network. Mol. Cell. Biol. 2009, 29:5251-5263.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 5251-5263
    • Pérez-Victoria, F.J.1    Bonifacino, J.S.2
  • 42
    • 11244351579 scopus 로고    scopus 로고
    • Function and regulation of cullin-RING ubiquitin ligases
    • Petroski M.D., Deshaies R.J. Function and regulation of cullin-RING ubiquitin ligases. Nat. Rev. Mol. Cell Biol. 2005, 6:9-20.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 9-20
    • Petroski, M.D.1    Deshaies, R.J.2
  • 43
    • 0032538835 scopus 로고    scopus 로고
    • Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes
    • Prekeris R., Klumperman J., Chen Y.A., Scheller R.H. Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes. J. Cell Biol. 1998, 143:957-971.
    • (1998) J. Cell Biol. , vol.143 , pp. 957-971
    • Prekeris, R.1    Klumperman, J.2    Chen, Y.A.3    Scheller, R.H.4
  • 44
    • 0345668477 scopus 로고    scopus 로고
    • The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex
    • Ratts R., Zeng H., Berg E.A., Blue C., McComb M.E., Costello C.E., vanderSpek J.C., Murphy J.R. The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex. J. Cell Biol. 2003, 160:1139-1150.
    • (2003) J. Cell Biol. , vol.160 , pp. 1139-1150
    • Ratts, R.1    Zeng, H.2    Berg, E.A.3    Blue, C.4    McComb, M.E.5    Costello, C.E.6    vanderSpek, J.C.7    Murphy, J.R.8
  • 46
    • 0023582912 scopus 로고
    • Acidification of the cytosol inhibits endocytosis from coated pits
    • Sandvig K., Olsnes S., Petersen O.W., van Deurs B. Acidification of the cytosol inhibits endocytosis from coated pits. J. Cell Biol. 1987, 105:679-689.
    • (1987) J. Cell Biol. , vol.105 , pp. 679-689
    • Sandvig, K.1    Olsnes, S.2    Petersen, O.W.3    van Deurs, B.4
  • 47
    • 0026353711 scopus 로고
    • Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect
    • Sandvig K., Prydz K., Hansen S.H., van Deurs B. Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect. J. Cell Biol. 1991, 115:971-981.
    • (1991) J. Cell Biol. , vol.115 , pp. 971-981
    • Sandvig, K.1    Prydz, K.2    Hansen, S.H.3    van Deurs, B.4
  • 48
    • 77953127589 scopus 로고    scopus 로고
    • Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
    • Sandvig K., Torgersen M.L., Engedal N., Skotland T., Iversen T.G. Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine. FEBS Lett. 2010, 584:2626-2634.
    • (2010) FEBS Lett. , vol.584 , pp. 2626-2634
    • Sandvig, K.1    Torgersen, M.L.2    Engedal, N.3    Skotland, T.4    Iversen, T.G.5
  • 50
    • 70549105793 scopus 로고    scopus 로고
    • Control of cell growth by the SCF and APC/C ubiquitin ligases
    • Skaar J.R., Pagano M. Control of cell growth by the SCF and APC/C ubiquitin ligases. Curr. Opin. Cell Biol. 2009, 21:816-824.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 816-824
    • Skaar, J.R.1    Pagano, M.2
  • 52
    • 56749176947 scopus 로고    scopus 로고
    • One step at a time: endoplasmic reticulum-associated degradation
    • Vembar S.S., Brodsky J.L. One step at a time: endoplasmic reticulum-associated degradation. Nat. Rev. Mol. Cell Biol. 2008, 9:944-957.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 944-957
    • Vembar, S.S.1    Brodsky, J.L.2
  • 54
    • 60849116672 scopus 로고    scopus 로고
    • Pseudomonas exotoxin A: from virulence factor to anti-cancer agent
    • Wolf P., Elsässer-Beile U. Pseudomonas exotoxin A: from virulence factor to anti-cancer agent. Int. J. Med. Microbiol. 2009, 299:161-176.
    • (2009) Int. J. Med. Microbiol. , vol.299 , pp. 161-176
    • Wolf, P.1    Elsässer-Beile, U.2
  • 55
    • 0025975785 scopus 로고
    • Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and Pseudomonas toxin
    • Yoshida T., Chen C.C., Zhang M.S., Wu H.C. Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and Pseudomonas toxin. Exp. Cell Res. 1991, 192:389-395.
    • (1991) Exp. Cell Res. , vol.192 , pp. 389-395
    • Yoshida, T.1    Chen, C.C.2    Zhang, M.S.3    Wu, H.C.4
  • 56
    • 33746641737 scopus 로고    scopus 로고
    • MBet3p is required for homotypic COPII vesicle tethering in mammalian cells
    • Yu S., Satoh A., Pypaert M., Mullen K., Hay J.C., Ferro-Novick S. mBet3p is required for homotypic COPII vesicle tethering in mammalian cells. J. Cell Biol. 2006, 174:359-368.
    • (2006) J. Cell Biol. , vol.174 , pp. 359-368
    • Yu, S.1    Satoh, A.2    Pypaert, M.3    Mullen, K.4    Hay, J.C.5    Ferro-Novick, S.6
  • 58
    • 27644531016 scopus 로고    scopus 로고
    • A quantitative and highly sensitive luciferase-based assay for bacterial toxins that inhibit protein synthesis
    • Zhao L., Haslam D.B. A quantitative and highly sensitive luciferase-based assay for bacterial toxins that inhibit protein synthesis. J. Med. Microbiol. 2005, 54:1023-1030.
    • (2005) J. Med. Microbiol. , vol.54 , pp. 1023-1030
    • Zhao, L.1    Haslam, D.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.