New nitric oxide or hydrogen sulfide releasing aspirins

Journal of Medicinal Chemistry

Volumn 54, Issue 15, 2011, Pages 5478-5484

  Lazzarato, Loretta ^a   Chegaev, Konstantin ^a   Marini, Elisabetta ^a   Rolando, Barbara ^a   Borretto, Emily ^a   Guglielmo, Stefano ^a   Joseph, Sony ^a   Di Stilo, Antonella ^a   Fruttero, Roberta ^a   Gasco, Alberto ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5 [4 (2 HYDROXYETHOXY)PHENYL) 3H 1,2 DITHIOLE 3 THIONE; [(3 NITROOXYPROPYL)CARBONYL]OXYMETHYL 2 (ACETYLOXY)BENZOATE; [4 (3 NITROOXYPROPYL)PHENOXYCARBONYL]OXYMETHYL 2 (ACETYLOXY)BENZOATE; [4 [2,3 BIS(NITROOXY)PROPYL]PHENOXYCARBONYL]OXYMETHYL; [[(OXY)CARBONYL]OXY]METHYL ESTER EDRIVATIVE; [[2 [4 (3 THIOXO 3H 1,2 DITHIOL 5 YL)PHENOXY]ETHOXY]CARBONYLOXY]METHYL 2 (ACETYLOXY)BENZOATE; [[2,3 BIS(NITROOXY)PROPYL]CARBONYL]OXYMETHYL 2 (ACETYLOXY)BENZOATE; [[4 (3 THIOXO 3H 1,2 DITHIOL 5 YL)PHENOXY]CARBONYLOXY]METHYL 2 (ACETYLOXY)BENZOATE; ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID DERIVATIVE; ANTICOAGULANT AGENT; ANTIINFLAMMATORY AGENT; BUFFER; HYDROGEN SULFIDE; NITRIC OXIDE DONOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AORTA; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; NONHUMAN; PH; RAT; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; AORTA, THORACIC; ASPIRIN; HUMANS; HYDROGEN SULFIDE; MALE; MUSCLE RELAXATION; NITRIC OXIDE; NITRIC OXIDE DONORS; PLATELET AGGREGATION INHIBITORS; RATS; RATS, WISTAR; VASODILATOR AGENTS;

EID: 79961244297     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm2004514     Document Type: Article

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