Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Peng, Ai ^a,b   Wu, Tianfu ^b   Zeng, Caihong ^c   Rakheja, Dinesh ^b   Zhu, Jiankun ^b   Ye, Ting ^b   Hutcheson, Jack ^b   Vaziri, Nosratola D ^d   Liu, Zhihong ^c   Mohan, Chandra ^b   Zhou, Xin J ^b  

^a TENTH PEOPLE S HOSPITAL OF TONGJI UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ENDOTHELIAL NITRIC OXIDE SYNTHASE; LY 492002; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PHOSPHATE; PROTEIN BAX; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA 2; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; BCL2L1 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOS3 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL X; PROTEIN KINASE C;

APOPTOSIS; ARTICLE; CARDIOVASCULAR DISEASE; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYPERPHOSPHATEMIA; HYPOPHOSPHATEMIA; IN VITRO STUDY; PHOSPHATE METABOLISM; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; INTRACELLULAR SPACE; METABOLISM; PATHOPHYSIOLOGY; WESTERN BLOTTING;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BLOTTING, WESTERN; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; HYPERPHOSPHATEMIA; HYPOPHOSPHATEMIA; INTRACELLULAR SPACE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHATES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 79961224247     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023268     Document Type: Article

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