Involvement of the H3O+-Lys-164-Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H+,K +-ATPase

Journal of Biological Chemistry

Volumn 283, Issue 24, 2008, Pages 16876-16884

  Morii, Magotoshi ^a,c   Yamauchi, Masashi ^a   Ichikawa, Tomohiko ^a   Fujii, Takuto ^a   Takahashi, Yuji ^a   Asano, Shinji ^b   Takeguchi, Noriaki ^a   Sakai, Hideki ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b RITSUMEIKAN UNIVERSITY   (Japan)

^c SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; CHARGE TRANSFER; DYNAMICS; HYDROLYSIS; ION EXCHANGE; ION SOURCES; MASS TRANSFER; MOLECULAR DYNAMICS; PROTONS; QUANTUM CHEMISTRY; THREE DIMENSIONAL;

ATP HYDROLYSES; ATPASE ACTIVITIES; CATION BINDINGS; CHARGE TRANSPORTS; CONFORMATIONAL TRANSITIONS; CYTOSOLIC; DIMENSIONAL STRUCTURES; GASTRIC VESICLES; HYDRONIUM IONS; MOLECULAR DYNAMICS SIMULATIONS; PROTON TRANSPORTS; TRANSFER PATHWAYS; TRANSPORT MECHANISMS;

PROTON TRANSFER;

8 BENZYLOXY 2 METHYLIMIDAZO[1,2 A]PYRIDINE 3 ACETONITRILE; GLUTAMIC ACID; GLUTAMINE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; HYDRONIUM ION; LEUCINE; LYSINE; WATER; ADENOSINE TRIPHOSPHATASE; PROTON;

ALPHA CHAIN; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME CONFORMATION; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; SIMULATION; STOMACH; SWINE; WATER TRANSPORT; ANIMAL; BINDING SITE; BIOLOGICAL MODEL; CYTOSOL; HYDROLYSIS; METABOLISM; MUTATION; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT; CYTOSOL; H(+)-K(+)-EXCHANGING ATPASE; HUMANS; HYDROLYSIS; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTONS; STOMACH; SWINE;

EID: 47749099719     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800563200     Document Type: Article

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