Large-scale opening of utrophin's tandem calponin homology (CH) domains upon actin binding by an induced-fit mechanism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 31, 2011, Pages 12729-12733

  Lin, Ava Y ^a   Prochniewicz, Ewa ^a   James, Zachary M ^a   Svensson, Bengt ^a   Thomas, David D ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Cryo EM; Pulsed EPR; Spectroscopy

Indexed keywords

ACTIN; CALPONIN; DYSTROPHIN; UTROPHIN;

ARTICLE; BECKER MUSCULAR DYSTROPHY; CRYSTAL STRUCTURE; DUCHENNE MUSCULAR DYSTROPHY; ELECTRON SPIN RESONANCE; MUSCULAR DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; SPIN LABELING;

ACTINS; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CIRCULAR DICHROISM; ELECTRON SPIN RESONANCE SPECTROSCOPY; KINETICS; MICE; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; UTROPHIN;

EID: 79961213117     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1106453108     Document Type: Article

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