Biochemical characterisation of the actin-binding properties of utrophin

Cell Motility and the Cytoskeleton

Volumn 46, Issue 2, 2000, Pages 116-128

  Moores, Carolyn A ^a,b   Kendrick Jones, John ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Actin isoforms; Calponin homology; Cosedimentation assay; Dystrophin related; Myosin S1; Spectrin superfamily

Indexed keywords

ACTIN BINDING PROTEIN; UTROPHIN;

ACTIN FILAMENT; AMINO TERMINAL SEQUENCE; ARTICLE; BECKER MUSCULAR DYSTROPHY; CROSS LINKING; DUCHENNE MUSCULAR DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CHICKENS; CHROMATOGRAPHY, GEL; CHYMOTRYPSIN; CYTOSKELETAL PROTEINS; DYSTROPHIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; IMMUNOBLOTTING; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYOSIN SUBFRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TRYPSIN; UTROPHIN;

VERTEBRATA;

EID: 0033918661     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0169(200006)46:2<116::AID-CM4>3.0.CO;2-L     Document Type: Article

References (60)

1. Amann KJ, Renley BA, Ervasti JM. 1998. A cluster of basic repeats in the dystrophin rod domain binds F-actin through an electrostatic interaction. J Biol Chem 273:28419-28423.
2. Amann KJ, Guo AW-X, Ervasti JM. 1999. Utrophin lacks the rod domain actin binding activity of dystrophin. J Biol Chem 274: 35375-35380.
3. Bassel G, Singer RH. 1997. mRNA and cytoskeletal filaments. Curr Opin Cell Biol 9:109-115.
4. Blake DJ, Tinsley JM, Davies KE. 1996. Utrophin: a structural and functional comparison to dystrophin. Brain Pathol 6:37-47.
5. Bresnick AR, Warren V, Condeelis J. 1990. Identification of a short sequence essential for actin binding by Dictyostelium ABP-120. J Biol Chem 265:9236-9240.
6. Buechler JA, Toner-Webb JA, Taylor SS. 1991. Carbodiimides as probes for protein kinase structure and function. Methods Enzymol 200:487-500.
7. Campanelli JT, Roberds SL, Campbell KP, Scheller RH. 1994. A role for dystrophin-associated glycoproteins and utrophin in agrin-induced AChR clustering. Cell 77:663-674.
8. Carugo KD, Bañuelos S, Saraste M. 1997. Crystal structure of a calponin homology domain. Nature Struct Biol 4:175-179.
9. Castresana J, Saraste M. 1995. Does Vav bind to F-actin through a CH domain? FEBS Lett 374:149-151.
10. Corrado K, Mills PL, Chamberlain JS. 1994. Deletion analysis of the dystrophin-actin binding domain. FEBS Lett 344:255-260.
11. Deconinck AE, Potter AC, Tinsley JM, Wood SJ, Vater R, Young C, Metzinger L, Vincent A, Slater CR, Davies KE. 1997. Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice. J Cell Biol 136:883-894.
12. Detmers P, Weber A, Elzinga M, Stephens RE. 1981. 7-chloro-4-nitrobenzeno-2-oxa-1,3-diazole actin as a probe for actin polymerisation. J Biol Chem 256:99-105.
13. Emery AEH. 1993. Duchenne muscular dystrophy. Oxford: Oxford University Press.
14. Ervasti JM, Campbell KP. 1993. A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin. J Cell Biol 122:809-823.
15. Fabbrizio E, Bonet-Kerrache A, Leger JJ, Mornet D. 1993. Actin-dystrophin interface. Biochemistry 32:10457-10463.
16. Goldsmith SC, Pokala N, Shen W, Fedorov AA, Matsudaira P, Almo SC. 1997. The structure of an actin-crosslinking domain from human fimbrin. Nature Struct Biol 4:708-712.
17. Grady RM, Merlie JP, Sanes JR. 1997. Subtle neuromuscular defects in utrophin-deficient mice. J Cell Biol 136:871-882.
18. Gramolini AO, Jasmin BJ. 1997. Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link. BioEssays 19: 747-750.
19. Hall ZW, Lubit BW, Schwartz JH. 1981. Cytoplasmic actin in postsynaptic structures at the neuromuscular junction. J Cell Biol 90:789-792.
20. Hanein D, Matsudaira P, DeRosier DJ. 1997. Evidence for a conformational change in actin induced by fimbrin (N375) binding. J Cell Biol 139:387-396.
21. Hanein D, Volkmann N, Goldsmith S, Michon A-M, Lehman W, Craig R, DeRosier D, Almo S, Matsudaira P. 1998. An atomic model of fimbrin binding to F-actin and its implications for filament cross-linking and regulation. Nature Struct Biol 5:787-792.
22. Hemmings L, Kuhlman PA, Critchley DR. 1992. Analysis of the actin-binding domain of α-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain. J Cell Biol 116:1369-1380.
23. Henry MD, Campbell KP. 1996. Dystroglycan: an extracellular matrix receptor linked to the cytoskeleton. Curr Opin Cell Biol 8:625-631.
24. Höfer D, Ness W, Drenckhahn D. 1997. Sorting of actin isoforms in chicken auditory hair cells. J Cell Sci 110:765-770.
25. Holmes KC, Popp D, Gebhard W, Kabsch W. 1990. Atomic model of the actin filament. Nature 347:44-49.
26. Karinch AM, Zimmer WE, Goodman SR. 1990. The identification and sequence of the actin-binding domain of human red blood cell beta-spectrin. J Biol Chem 265:11833-11840.
27. Keep NH, Norwood FLM, Moores CA, Winder SJ, Kendrick-Jones J. 1999a. The 2.0Å structure of the second calponin homology domain from the actin-binding region of the dystrophin homologue utrophin. J Mol Biol 285:1257-1264.
28. Keep NH, Winder SJ, Moores CA, Walke S, Norwood FLM, Kendrick-Jones J. 1999b. Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer. Structure 7:1539-1546.
29. Khurana TS, Kunkel LM, Frederickson AD, Carbonetto S, Watkins SC. 1995. Interaction of chromosome 6-encoded dystrophin-related protein in the brain. J Cell Biol 119:357-366.
30. Kraulis PJ. 1991. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J Appl Crystallogr 24:946-950.
31. Kuhlman PA, Ellis J, Critchley DR, Bagshaw CR. 1994. The kinetics of the interaction between the actin-binding domain of α-actinin and F-actin. FEBS Lett 339:297-301.
32. Lebart M-C, Mejean C, Roustan C, Benyamin Y. 1993. Further characterisation of the α-actinin-actin interface and comparison with filamin-binding sites on actin. J Biol Chem 268:5642-5648.
33. Levine BA, Moir AJG, Patchell VB, Perry SV. 1990. The interaction of actin with dystrophin. FEBS Lett 263:159-162.
34. Levine BA, Moir AJG, Patchell VB, Perry SV. 1992. Binding sites involved in the interaction of actin with the N-terminal region of dystrophin. FEBS Lett 298:44-48.
35. Margossian SS, Lowey S. 1982. Preparation of myosin and its subfragments from rabbit skeletal muscle. Methods Enzymol 85: 55-71.
36. McGough A. 1998. F-actin binding proteins. Curr Opin Struct Biol 8:166-176.
37. McGough A, Way M, DeRosier D. 1994. Determination of the α-actinin binding site on actin filaments by cryoelectron microscopy and image analysis. J Cell Biol 126:433-443.
38. Merritt EA, Bacon DJ. 1997. Raster3D: photorealistic molecular graphics. Methods Enzymol 277:505-524.
39. Meyer RK, Aebi U. 1990. Bundling of actin filaments by α-actinin depends on its molecular length. J Cell Biol 110:2013-2024.
40. Moores CA, Keep NH, Kendrick-Jones J. 2000. Structure of the utrophin actin-binding domain bound to F-actin reveals binding by an induced fit mechanism. J Mol Biol 297:465-480.
41. Morris GE, Man N, Huyem NN, Pereboev A, Kendrick-Jones J, Winder SJ. 1999. Disruption of the utrophin-actin interaction by monoclonal antibodies and prediction of an actin-binding surface of utrophin. Biochem J 337:119-123.
42. Ohlendieck K, Ervasti JM, Matsumara K, Kahl SD, Leveille CJ, Campbell KP. 1991. Dystrophin-related protein is localised to neuromuscular junctions of adult skeletal muscle. Neuron 7:499-508.
43. Pollard TD. 1999. Actin and associated proteins. In: Kreis T, Vale R, editors. Guidebook to the cytoskeletal and motor proteins. 2nd ed. New York: Oxford University Press. p 3-11.
44. Rayment I, Holden HM, Whittaker M, Yohn CB, Lorenz M, Holmes KC, Milligan RA. 1993. Structure of the actin-myosin complex and its implications for muscle contraction. Science 261:58-65.
45. Renley BA, Rybokova IN, Amann KJ, Ervasti JM. 1998. Dystrophin binding to nonmuscle actin. Cell Motil Cytoskeleton 41:264-270.
46. Rigoletto C, Prelle A, Ciscato P, Moggio M, Comi G, Fortunato F, Scarlato G. 1995. Utrophin expression during human fetal development. Int J Dev Neurosci 13:585-593.
47. Rubenstein PA. 1990. The functional importance of multiple actin isoforms. BioEssays 12:309-315.
48. Rybakova I, Amann KJ, Ervasti JM. 1996. A new model for the interaction of dystrophin with F-actin. J Cell Biol 135:661-672.
49. Spudich JA, Watt S. 1971. The regulation of rabbit skeletal contraction I. Biochemical studies of the interaction of the tropomyosintroponin complex with actin and the proteolytic fragments of myosin. J Biol Chem 246:4866-4871.
50. Stradel T, Kranewitter W, Winder SJ, Gimona M. 1998. CH domains revisited. FEBS Lett 431:134-137.
51. Thompson JD, Higgins DG, Gibson TJ. 1994. CLUSTAL W: improving sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix. Nucleic Acids Res 22:4673-4680.
52. Tinsley JM, Blake DJ, Roche A, Fairbrother U, Riss J, Byth BC, Knight AE, Kendrick-Jones J, Suthers GK, Love DR, Edwards YH, Davies KE. 1992. Primary structure of dystrophin-related protein. Nature 360:591-593.
53. Tinsley J, Deconinck N, Fisher R, Kahn D, Phelps S, Gillis J-M, Davies K. 1998. Expression of full-length utrophin prevents muscular dystrophy in mdx mice. Nature Med 4:1441-1444.
54. Way M, Pope B, Cross RA, Kendrick-Jones J, Weeds AG. 1992. Expression of the N-terminal domain of dystrophin in E. coli and demonstration of binding to F-actin. FEBS Lett 301:243-245.
55. Winder SJ. 1996. Structure-function relationships in dystrophin and utrophin. Biochem Soc Trans 24:497-501.
56. Winder SJ. 1997. The membrane-cytoskeleton interface: the role of dystrophin and utrophin. J Muscle Res Cell Motil 18:617-629.
57. Winder SJ, Kendrick-Jones J. 1995a. Protein production in three different expression vectors from a single polymerase chain reaction product. Anal Biochem 231:271-273.
58. Winder SJ, Kendrick-Jones J. 1995b. Calcium/calmodulin-dependent regulation of the N-terminal F-actin binding domain of utrophin. FEBS Lett 357:125-128.
59. Winder SJ, Hemmings L, Maciver SK, Bolton SJ, Tinsley JM, Davies KE, Critchley DR, Kendrick-Jones J. 1995. Utrophin actin-binding domain - analysis of actin-binding and cellular targeting. J Cell Sci 108:63-71.
60. Winder SJ, Knight AE, Kendrick-Jones J. 1997. Protein structure. In: Brown SS, Lucy JA, editors. Dystrophin: gene, protein and cell biology. Cambridge: Cambridge University Press. p 27-55.