메뉴 건너뛰기




Volumn 31, Issue 7, 2011, Pages 2535-2539

KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines

Author keywords

Colon cancer; KRAS; RRM2

Indexed keywords

DNA; K RAS PROTEIN; OXIDOREDUCTASE INHIBITOR; RIBONUCLEOTIDE REDUCTASE; RIBONUCLEOTIDE REDUCTASE M2; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

EID: 79961195301     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (34)

References (31)
  • 1
    • 0027905014 scopus 로고
    • Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
    • Shirasawa S, Furuse M, Yokoyama N and Sasazuki T: Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science 260: 85-88, 1993. (Pubitemid 23122749)
    • (1993) Science , vol.259 , Issue.5104 , pp. 85-88
    • Shirasawa, S.1    Furuse, M.2    Yokoyama, N.3    Sasazuki, T.4
  • 4
    • 13544256266 scopus 로고    scopus 로고
    • Oncogenic events regulate tissue factor expression in colorectal cancer cells: Implications for tumor progression and angiogenesis
    • DOI 10.1182/blood-2004-05-2042
    • Yu JL, May L, Lhotak V, Shahrzad S, Shirasawa S, Weitz JI, Coomber BL, Mackman N and Rak JW: Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis. Blood 105: 1734-1741, 2005. (Pubitemid 40223697)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1734-1741
    • Yu, J.L.1    May, L.2    Lhotak, V.3    Shahrzad, S.4    Shirasawa, S.5    Weitz, J.I.6    Coomber, B.L.7    Mackman, N.8    Rak, J.W.9
  • 5
    • 77954296394 scopus 로고    scopus 로고
    • 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors
    • She QB, Halilovic E, Ye Q, Zhen W, Shirasawa S, Sasazuki T, Solit DB and Rosen N: 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors. Cancer Cell 18: 39-51, 2010.
    • (2010) Cancer Cell , vol.18 , pp. 39-51
    • She, Q.B.1    Halilovic, E.2    Ye, Q.3    Zhen, W.4    Shirasawa, S.5    Sasazuki, T.6    Solit, D.B.7    Rosen, N.8
  • 7
    • 0034671497 scopus 로고    scopus 로고
    • Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-ras signaling pathway in human colon cancer cells
    • Baba I, Shirasawa S, Iwamoto R, Okumura K, Tsunoda T, Nishioka M, Fukuyama K, Yamamoto K, Mekada E and Sasazuki T: Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells. Cancer Res 60: 6886-6889, 2000. (Pubitemid 32059159)
    • (2000) Cancer Research , vol.60 , Issue.24 , pp. 6886-6889
    • Baba, I.1    Shirasawa, S.2    Iwamoto, R.3    Okumura, K.4    Tsunoda, T.5    Nishioka, M.6    Fukuyama, K.7    Yamamoto, K.8    Mekada, E.9    Sasazuki, T.10
  • 8
    • 0442293930 scopus 로고    scopus 로고
    • Deregulated expression of KRAP, a novel gene encoding actin-interacting protein, in human colon cancer cells
    • DOI 10.1007/s10038-003-0106-3
    • Inokuchi J, Komiya M, Baba I, Naito S, Sasazuki T and Shirasawa S: Deregulated expression of KRAP, a novel gene encoding actin-interacting protein, in human colon cancer cells. J Hum Genet 49: 46-52, 2004. (Pubitemid 38186125)
    • (2004) Journal of Human Genetics , vol.49 , Issue.1 , pp. 46-52
    • Inokuchi, J.1    Komiya, M.2    Baba, I.3    Naito, S.4    Sasazuki, T.5    Shirasawa, S.6
  • 9
    • 33746370368 scopus 로고    scopus 로고
    • Ribonucleotide reductases
    • DOI 10.1146/annurev.biochem.75.103004.142443
    • Nordlund P and Reichard P: Ribonucleotide reductases. Annu Rev Biochem 75: 681-706, 2006. (Pubitemid 44118048)
    • (2006) Annual Review of Biochemistry , vol.75 , pp. 681-706
    • Nordlund, P.1    Reichard, P.2
  • 12
    • 33847417505 scopus 로고    scopus 로고
    • Ribonucleotide reductase subunits M2 and p53R2 are potential biomarkers for metastasis of colon cancer
    • Liu X, Zhou B, Xue L, Yen F, Chu P, Un F and Yen Y: Ribonucleotide reductase subunits M2 and p53R2 are potential biomarkers for metastasis of colon cancer. Clin Colorectal Cancer 6: 374-381, 2007. (Pubitemid 46340204)
    • (2007) Clinical Colorectal Cancer , vol.6 , Issue.5 , pp. 374-381
    • Liu, X.1    Zhou, B.2    Xue, L.3    Yen, F.4    Chu, P.5    Un, F.6    Yen, Y.7
  • 13
    • 0030450403 scopus 로고    scopus 로고
    • Ribonucleotide reductase R2 component is a novel malignancy determinant that cooperates with activated oncogenes to determine transformation and malignant potential
    • DOI 10.1073/pnas.93.24.14036
    • Fan H, Villegas C and Wright JA: Ribonucleotide reductase R2 component is a novel malignancy determinant that cooperates with activated oncogenes to determine transformation and malignant potential. Proc Natl Acad Sci USA 93: 14036-14040, 1996. (Pubitemid 26424241)
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , Issue.24 , pp. 14036-14040
    • Fan, H.1    Villegas, C.2    Wright, J.A.3
  • 14
    • 1542742114 scopus 로고    scopus 로고
    • RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine
    • DOI 10.1038/sj.onc.1207272
    • Duxbury MS, Ito H, Zinner MJ, Ashley SW and Whang EE: RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene 23: 1539-1548, 2004. (Pubitemid 38406516)
    • (2004) Oncogene , vol.23 , Issue.8 , pp. 1539-1548
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3    Ashley, S.W.4    Whang, E.E.5
  • 15
    • 23844466231 scopus 로고    scopus 로고
    • Increased expression of the large subunit of ribonucleotide reductase is involved in resistance to gemcitabine in human mammary adenocarcinoma cells
    • DOI 10.1158/1535-7163.MCT-05-0121
    • Jordheim LP, Guittet O, Lepoivre M, Galmarini CM and Dumontet C: Increased expression of the large subunit of ribonucleotide reductase is involved in resistance to gemcitabine in human mammary adenocarcinoma cells. Mol Cancer Ther 4: 1268-1276, 2005. (Pubitemid 41149575)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.8 , pp. 1268-1276
    • Jordheim, L.P.1    Guittet, O.2    Lepoivre, M.3    Galmarini, C.M.4    Dumontet, C.5
  • 16
    • 0141455148 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of Triapine, a potent ribonucleotide reductase inhibitor, administered daily for five days in patients with advanced solid tumors
    • Murren J, Modiano M, Clairmont C, Lambert P, Savaraj N, Doyle T and Sznol M: Phase I and pharmacokinetic study of triapine, a potent ribonucleotide reductase inhibitor, administered daily for five days in patients with advanced solid tumors. Clin Cancer Res 9: 4092-4100, 2003. (Pubitemid 37204025)
    • (2003) Clinical Cancer Research , vol.9 , Issue.11 , pp. 4092-4100
    • Murren, J.1    Modiano, M.2    Clairmont, C.3    Lambert, P.4    Savaraj, N.5    Doyle, T.6    Sznol, M.7
  • 17
    • 74149093251 scopus 로고    scopus 로고
    • A phase II trial of triapine (NSC# 663249) and gemcitabine as second-line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503
    • Traynor AM, Lee JW, Bayer GK, Tate JM, Thomas SP, Mazurczak M, Graham DL, Kolesar JM and Schiller JH: A phase II trial of triapine (NSC# 663249) and gemcitabine as second-line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503. Invest New Drugs 28: 91-97, 2010.
    • (2010) Invest New Drugs , vol.28 , pp. 91-97
    • Traynor, A.M.1    Lee, J.W.2    Bayer, G.K.3    Tate, J.M.4    Thomas, S.P.5    Mazurczak, M.6    Graham, D.L.7    Kolesar, J.M.8    Schiller, J.H.9
  • 20
    • 36448987897 scopus 로고    scopus 로고
    • Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line
    • DOI 10.1007/s10038-007-0204-8
    • Fujimoto T, Koyanagi M, Baba I, Nakabayashi K, Kato N, Sasazuki T and Shirasawa S: Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line. J Hum Genet 52: 978-984, 2007. (Pubitemid 350164615)
    • (2007) Journal of Human Genetics , vol.52 , Issue.12 , pp. 978-984
    • Fujimoto, T.1    Koyanagi, M.2    Baba, I.3    Nakabayashi, K.4    Kato, N.5    Sasazuki, T.6    Shirasawa, S.7
  • 21
    • 33846205171 scopus 로고    scopus 로고
    • A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration
    • DOI 10.1158/0008-5472.CAN-06-1878
    • Goldberg L and Kloog Y: A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration. Cancer Res 66: 11709-11717, 2006. (Pubitemid 46094183)
    • (2006) Cancer Research , vol.66 , Issue.24 , pp. 11709-11717
    • Goldberg, L.1    Kloog, Y.2
  • 22
    • 61849162778 scopus 로고    scopus 로고
    • Glutamine deprivation induces abortive S-phase rescued by deoxyribonucleotides in K-ras transformed fibroblasts
    • Gaglio D, Soldati C, Vanoni M, Alberghina L and Chiaradonna F: Glutamine deprivation induces abortive S-phase rescued by deoxyribonucleotides in K-ras transformed fibroblasts. PLoS One 4: e4715, 2009.
    • (2009) PLoS One , vol.4
    • Gaglio, D.1    Soldati, C.2    Vanoni, M.3    Alberghina, L.4    Chiaradonna, F.5
  • 23
    • 77649336663 scopus 로고
    • Metabolic genes in cancer: Their roles in tumor progression and clinical implications
    • Furuta E, Okuda H, Kobayashi A and Watabe K: Metabolic genes in cancer: their roles in tumor progression and clinical implications. Biochim Biophys Acta 1805: 141-152,
    • (1805) Biochim Biophys Acta , pp. 141-152
    • Furuta, E.1    Okuda, H.2    Kobayashi, A.3    Watabe, K.4
  • 24
    • 0033079597 scopus 로고    scopus 로고
    • Oncogenic alterations of metabolism
    • Dang CV and Semenza GL: Oncogenic alterations of metabolism. Trends Biochem Sci 24: 68-72, 1999.
    • (1999) Trends Biochem Sci , vol.24 , pp. 68-72
    • Dang, C.V.1    Semenza, G.L.2
  • 25
    • 0030614893 scopus 로고    scopus 로고
    • 2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
    • DOI 10.1038/nm0297-177
    • 2 gradients in solid tumors in vitro: high-resolution mesurements reveal a lack of correlation. Nat Med 3: 177-182, 1997. (Pubitemid 27064702)
    • (1997) Nature Medicine , vol.3 , Issue.2 , pp. 177-182
    • Helmlinger, G.1    Yuan, F.2    Dellian, M.3    Jain, R.K.4
  • 26
    • 0024281372 scopus 로고
    • Cell and enviroment interactions in tumor microgenesis: The multicell spheroid model
    • Southerland RM: Cell and enviroment interactions in tumor microgenesis: the multicell spheroid model. Science 240: 178-184, 1988.
    • (1988) Science , vol.240 , pp. 178-184
    • Southerland, R.M.1
  • 27
    • 0037031895 scopus 로고    scopus 로고
    • Hypoxia and nitric oxide treatment confer tolerance to glucose starvation in a 5′-AMP-activated protein kinase-dependent manner
    • DOI 10.1074/jbc.M112270200
    • Esumi H, Izuishi K, Kato K, Hashimoto K, Kurashima Y, Kishimoto A, Ogura T and Ozawa T: Hypoxia and nitric oxide treatment confer tolerance to glucose starvation in a 5′-AMP-activated protein kinase-dependent manner. J Biol Chem 277: 32791-32798, 2002. (Pubitemid 34984788)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.36 , pp. 32791-32798
    • Esumi, H.1    Izuishi, K.2    Kato, K.3    Hashimoto, K.4    Kurashima, Y.5    Kishimoto, A.6    Ogura, T.7    Ozawa, T.8
  • 28
    • 0142120469 scopus 로고    scopus 로고
    • ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation
    • DOI 10.1038/sj.onc.1206899
    • Suzuki A, Kusakai G, Kishimoto A, Lu J, Ogura T and Esumi H: ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation. Oncogene 22: 6177-6182, 2003. (Pubitemid 37281647)
    • (2003) Oncogene , vol.22 , Issue.40 , pp. 6177-6182
    • Suzuki, A.1    Kusakai, G.-I.2    Kishimoto, A.3    Lu, J.4    Ogura, T.5    Esumi, H.6
  • 29
    • 0037427833 scopus 로고    scopus 로고
    • Induction of matrix metalloproteinase gene transcription by nitric oxide and mechanisms of MMP-1 gene induction in human melanoma cell lines
    • DOI 10.1002/ijc.10808
    • Ishii Y, Ogura T, Tatemichi M, Fujisawa H, Otsuka F and Esumi H: Induction of matrix metalloproteinase gene transcription by nitric oxide and mechanisms of MMP-1 gene induction in human melanoma cell lines. Int J Cancer 103: 161-168, 2003. (Pubitemid 35461507)
    • (2003) International Journal of Cancer , vol.103 , Issue.2 , pp. 161-168
    • Ishii, Y.1    Ogura, T.2    Tatemichi, M.3    Fujisawa, H.4    Otsuka, F.5    Esumi, H.6
  • 30
    • 35448980704 scopus 로고    scopus 로고
    • Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
    • DOI 10.1158/0008-5472.CAN-07-1462
    • Sato K, Tsuchihara K, Fujii S, Sugiyama M, Goya T, Atomi Y, Ueno T, Ochiai A and Esumi H: Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res 67: 9677-9684, 2007. (Pubitemid 47621214)
    • (2007) Cancer Research , vol.67 , Issue.20 , pp. 9677-9684
    • Sato, K.1    Tsuchihara, K.2    Fujii, S.3    Sugiyama, M.4    Goya, T.5    Atomi, Y.6    Ueno, T.7    Ochiai, A.8    Esumi, H.9
  • 31
    • 0035929359 scopus 로고    scopus 로고
    • Cell cycle regulation via p53 phosphorylation by a 5′-AMP activated protein kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D- ribofuranoside, in a human hepatocellular carcinoma cell line
    • DOI 10.1006/bbrc.2001.5627
    • Imamura K, Ogura T, Kishimoto A, Kaminishi M and Esumi H: Cell cycle regulation via p53 phosphorylation by a 5′-AMP-activated protein kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line. Biochem Biophys Res Commun 287: 562-567, 2001. (Pubitemid 32917636)
    • (2001) Biochemical and Biophysical Research Communications , vol.287 , Issue.2 , pp. 562-567
    • Imamura, K.1    Ogura, T.2    Kishimoto, A.3    Kaminishi, M.4    Esumi, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.