Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 16, 2011, Pages 4928-4934

  Hassan, Hossam M ^a,b   Sallam, Asmaa A ^a   Mohammed, Rabab ^b   Hifnawy, Mohamed S ^c   Youssef, Diaa T A ^d   El Sayed, Khalid A ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

^b Beni Suef University   (Egypt)

^c Nahda University   (Egypt)

^d KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

Antimigratory; Breast cancer; Carbamoylation; Cembranoids; Etherification; Prostate cancer; Semisynthesis; Wound healing

Indexed keywords

7BETA ALLYL[ALLYL(ALLYLCARBAMOYL)CARBAMOYL] 8(19)DELTA DEEPOXYSARCOPHINE; 7BETA BUTYLCARBAMOYL 8(19)DELTA DEEPOXYSARCOPHINE; 7BETA BUTYOXYL 8ALPHA HYDROXYDEEPOXYSARCOPHINE; 7BETA CHLOROPROPYLCARBAMOYL 8(19)DELTA DEEPOXYSARCOPHINE; 7BETA CYCLOHEXYLCARBAMOYL 8(19)DELTA DEEPOXYSARCOPHINE; 7BETA PENTYLCARBAMOYL 8(19)DELTA DEEPOXYSARCOPHINE; 7BETA PHENYLLCARBAMOYL 8(19)DELTA DEEPOXYSARCOPHINE; 7BETA PROPYLOXY 8ALPHA HYDROXYDEEPOXYSARCOPHINE; ANTINEOPLASTIC AGENT; CEMBRANOID; ESTROGEN RECEPTOR; SARCOPHINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMGIRATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CARBAMOYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; CELL ASSAY; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORAL; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ETHERIFICATION; HUMAN; HUMAN CELL; IC 50; PROSTATE CANCER; PROTON NUCLEAR MAGNETIC RESONANCE; SARCOPHYTON GLAUCUM; SOLVENT EXTRACTION; STRUCTURE ACTIVITY RELATION; WOUND HEALING ASSAY;

4-BUTYROLACTONE; ANIMALS; ANTHOZOA; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MIGRATION ASSAYS; CELL MIGRATION INHIBITION; CELL PROLIFERATION; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; INDIAN OCEAN; MALE; PROSTATIC NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP;

ALCYONACEA; SARCOPHYTON GLAUCUM;

EID: 79961166820     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.06.060     Document Type: Article

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