Chemopreventive effects of sarcophine-diol on ultraviolet B-induced skin tumor development in SKH-1 hairless mice

Marine Drugs

Volumn 7, Issue 2, 2009, Pages 153-165

  Zhang, Xiaoying ^a   Bommareddy, Ajay ^b   Chen, Wei ^a   Hildreth, Michael B ^a   Kaushik, Radhey S ^a   Zeman, David ^a   Khalifa, Sherief ^c   Fahmy, Hesham ^a   Dwivedi, Chandradhar ^a  

^a SOUTH DAKOTA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c Egypt   (Egypt)

Author keywords

Apoptosis; Chemopreventive agent; Sarcophine diol; Skin cancer

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; FISH VENOM; SARCOPHINEDIOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER PREVENTION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA DEGRADATION; DRUG MECHANISM; FEMALE; MOUSE; NICK END LABELING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; RADIATION CARCINOGENESIS; SKIN CARCINOGENESIS; SKIN TUMOR; TOPICAL TREATMENT; ULTRAVIOLET B RADIATION; WESTERN BLOTTING;

MUS;

EID: 66449108270     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md7020153     Document Type: Article

References (33)

1. Mantena, S.K.; Sharma, S.D.; Katiyar, S.K. Berberine inhibits growth, induces G1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase 3 and PARP. Carcinogenesis 2006, 27, 2018-2027. (Pubitemid 44530576)
2. American Cancer Society Publication. Cancer Facts & Figures-2008. Available online: http://www.cancer.org/docroot/STT/content/STT-1x-Cancer-Facts- and-Figures-2008.asp?from=fast
3. Naylor, M.F.; Boyd, A.; Smith, D.W.; Cameron, G.S.; Hubbard, D.; Neldner, K.H. High sun protection factor sunscreens in the uppression of actinic neoplasia. Arch. Dermatol. 1995, 131, 170-175.
4. Yusuf, N.; Irby, C.; Katiyar, S.K.; Elmets, C.A. Photoprotective effects of green tea polyphenols. Photodermatol. Photoimmunol. Photomed. 2007, 23, 48-56.
5. Koh, H.K. Preventive strategies and research for ultraviolet-associated cancer. Environ. Health Perspect. 1995, 103, 255-257.
6. Learn, D.B.; Beasley, D.G.; Giddens, L.D.; Beard, J.; Stanfield, J.W.; Roberts, L.K. Minimum doses of ultraviolet radiation required to induce murine skin edema and immunosuppression are different and depend on the ultraviolet emission spectrum of the source. Photochem. Photobiol. 1995, 62, 1066-1075.
7. Soehnge, H.; Ouhtit, A.; Ananthaswamy, H.N. Mechanisms of induction of skin cancer by UV radiation. Front Biosci. 1997, 2, 538-551.
8. Kraemer, K.H. Sunlight and skin cancer: another link revealed. Proc. Natl. Acad. Sci. 1997, 94, 11-14.
9. De Gruijl, F.R.; Forbes, P.D. UV-induced skin cancer in a hairless mouse model. BioEssays 1995, 17, 651-660.
10. Forbes, P.D. Relevance of animal models of photocarcinogenesis to humans. Photochem. Photobiol. 1996, 63, 357-362.
11. Willis, I.; Menter, J.M.; Whyte, H.J. The rapid induction of cancers in the hairless mouse utilizing the principle of photoaugmentation. J. Invest. Dematol. 1981, 76, 404-408.
12. Bowden, G.T. Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signaling. Nat. Rev. Cancer 2004, 4, 23-35.
13. Haefner, B. Drugs from the deep: marine natural products as drug candidates. Drug Discov. Today 2003, 8, 536-544. (Pubitemid 36773671)
14. Fahmy, H.; Khalifa, S.; Konoshima, T.; Zjawiony, J.K. An improved synthesis of 7, 8-epoxy-1, 3, 11-cembratriene-15R (α), 16-diol, a cembranoid of marine origin with a potent cancer chemopreventive activity. Mar. Drugs 2002, 2, 1-7.
15. Fahmy, H.; Zjawiony, J.K.; Konoshima, T.; Tokuda, H.; Khan, S.; Khalifa, S. Potent skin cancer chemopreventing activity of some novel semi-synthesis cembranoids from marine sources. Mar. Drugs 2006, 4, 1-9. (Pubitemid 43763916)
16. Kundoor, V.; Zhang, X.; Khalifa, S.; Fahmy, H.; Dwivedi, C. A possible mechanism of action of the chemopreventive effects of sarcotriol on skin tumor development in CD-1 mice. Mar. Drugs 2006, 4, 274-285. (Pubitemid 46100513)
17. Zhang, X.; Kundoor, V.; Khalifa, S.; Zeman, D.; Fahmy, H.; Dwivedi, C. Chemopreventive effects of sarcophine-diol on skin tumor development in CD-1 mice. Cancer Lett. 2007, 253, 53-59. (Pubitemid 46874726)
18. Kundoor, V.; Zhang, X.; Bommareddy, A.; Khalifa, S.; Fahmy, H.; Dwivedi, C. Chemopreventive effects of sarcotriol on ultraviolet B-induced skin tumor development in SKH-1 hairless mice. Mar. Drugs 2007, 5, 197-207.
19. Kaur, M.; Agarwal, C.; Singh, R.P.; Guan, X.; Dwivedi, C.; Agarwal, R. Skin cancer chemopreventive agent, α-santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release. Carcinogenesis 2005, 26, 369-380. (Pubitemid 40246558)
20. Katsuyama, I.; Fahmy, H.; Zjawiony, J.K.; Khalifa, S.; Kilada, R.W.; Konoshima, T.; Takasaki, M.; Tokuda, H. Semisythesis of new sarcophine derivatives with chemopreventive activity. J. Nat. Prod. 2002, 65, 1809-1814.
21. Dwivedi, C.; Valluri, H.B.; Guan, X.; Agarwal, R. Chemopreventive effects of α-santalol on ultraviolet B radiation-induced skin tumor development in SKH-1 hairless mice. Carcinogenesis 2006, 27, 1917-1922. (Pubitemid 44288673)
22. Vermes, I.; Haanen, C.; Reutelingsperger, C. Flow cytometry of apoptotic cell death. J. Immunol. Methods 2000, 243, 167-190.
23. Schwartzman, R.; Cidlowski, J.A. Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocr. Rev. 1993, 14, 133-151.
24. Ne'eman, I.; Fishelson, L.; Kashman, Y. Sarcophine-a new toxin from the soft coral Sarcophyton glaucum (Alcyonaria). Toxicon 1974, 12, 593-598.
25. Sawant, S.; Youssef, D.; Mayer, A.; Sylvester, P.; Wali, V.; Arant, M.; Sayed, K.E. Anticancer and anti-inflammatory sulfur-containing semisynthetic derivatives of sarcophine. Chem. Pharm. Bull. 2006, 54, 1119-1123.
26. Arasada, B.L.; Bommareddy, A.; Zhang, X.; Bremmon, K.; Dwivedi, C. Effects of α-santalol on proapoptotic caspases and p53 expression in UVB irradiated mouse skin. Anticancer Res. 2008, 28, 129-132.
27. Meeran, S.M.; Mantena, S.K.; Elmets, C.A.; Katiyar, S.K. (-)-Epigallocatechin-3-gallate prevents photocarcinogenesis in mice through interleukin-12-dependent DNA repair. Cancer Res. 2006, 66, 5512-5520. (Pubitemid 43844980)
28. Katiyar, K.S.; Korman, N.J.; Mukhtar, H.; Agarwal, R. Protective effects of silymarin against photocarcinogenesis in a mouse skin model. J. Natl. Cancer Inst. 1997, 89, 556-565.
29. Dhanalakshmi, S.; Mallikarjuna, G.U.; Singh, R.P.; Agarwal, R. Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis. Carcinogenesis 2004, 25, 1459-1465. (Pubitemid 39162712)
30. Debatin, K. Apoptosis pathway in cancer and cancer therapy. Cancer Immunol. Immunother. 2004, 53, 153-159.
31. Brady, H.J. Apoptosis and leukaemia. Br. J. Haematol. 2003, 123, 577-585.
32. Ghobrial, I.M.; Witzig, T.E.; Adjei, A.A. Targeting apoptosis pathways in cancer therapy. CACancer J. Clin. 2005, 55, 178-194.
33. Zhang, X.; Bommareddy, A.; Chen, W.; Khalifa, S.; Kaushik, R.S.; Fahmy, H.; Dwivedi, C. Sarcophine-diol, a chemopreventive agent of skin cancer, inhibits cell growth and induces apoptosis through extrinsic pathway in human epidermoid carcinoma A431 cells. Transl. Oncol. 2009, 2, 21-30.