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Volumn 71, Issue 11, 2011, Pages 1413-1439

Difficult-to-treat gouty arthritis: A disease warranting better management

Author keywords

Allopurinol; BCX 4208; Canakinumab; Colchicine; Corticosteroids; Febuxostat; Gouty arthritis; Lesinurad; Nonsteroidal anti inflammatories; Pegadricase; Pegloticase; Quality of life; Rilonacept; Tranilast; Uricosurics.

Indexed keywords

ALLOPURINOL; ANTIGOUT AGENT; BCX 4208; BENZBROMARONE; CANAKINUMAB; COLCHICINE; CORTICOSTEROID; CORTICOTROPIN; ETORICOXIB; FEBUXOSTAT; INDOMETACIN; INTERLEUKIN 1BETA; LESINURAD; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PEGADRICASE; PEGLOTICASE; PREDNISOLONE; PROBENECID; RDEA 594; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACEPT; SULFINPYRAZONE; TRANILAST; TRIAMCINOLONE ACETONIDE; UNCLASSIFIED DRUG; URATE; URICOSURIC AGENT;

EID: 79961132862     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.2165/11592290-000000000-00000     Document Type: Review
Times cited : (40)

References (125)
  • 1
    • 38849106135 scopus 로고    scopus 로고
    • Diagnosis of gout
    • Schlesinger N. Diagnosis of gout. Minerva Med 2007; 98 (6): 759-67. (Pubitemid 351196064)
    • (2007) Minerva Medica , vol.98 , Issue.6 , pp. 759-767
    • Schlesinger, N.1
  • 2
    • 28444465148 scopus 로고    scopus 로고
    • Diagnosis of gout: Clinical, laboratory, and radiologic findings
    • quiz 465-8
    • Schlesinger N. Diagnosis of gout: clinical, laboratory, and radiologic findings. Am JManag Care 2005; 11 Suppl. 15: 443-50; quiz 465-8.
    • (2005) Am JManag Care , vol.11 , Issue.SUPPL.15 , pp. 443-450
    • Schlesinger, N.1
  • 3
    • 55249127091 scopus 로고    scopus 로고
    • Clinical manifestations of hyperuricemia and gout
    • Mandell BF. Clinical manifestations of hyperuricemia and gout. Cleve Clin J Med 2008; 75 Suppl. 5: 5-8.
    • (2008) Cleve Clin J Med , vol.75 , Issue.SUPPL. 5 , pp. 5-8
    • Mandell, B.F.1
  • 4
    • 67651225617 scopus 로고    scopus 로고
    • Mechanisms of bone erosion in gout: A quantitative analysis using plain radiography and computed tomography
    • Dalbeth N, Clark B, Gregory K, et al. Mechanisms of bone erosion in gout: a quantitative analysis using plain radiography and computed tomography. Ann Rheum Dis 2009; 68 (8): 1290-5.
    • (2009) Ann Rheum Dis , vol.68 , Issue.8 , pp. 1290-1295
    • Dalbeth, N.1    Clark, B.2    Gregory, K.3
  • 5
    • 78149484804 scopus 로고    scopus 로고
    • The pathogenesis of bone erosions in gouty arthritis
    • Schlesinger N, Thiele RG. The pathogenesis of bone erosions in gouty arthritis. Ann Rheum Dis 2010; 69 (11): 1907-12.
    • (2010) Ann Rheum Dis , vol.69 , Issue.11 , pp. 1907-1912
    • Schlesinger, N.1    Thiele, R.G.2
  • 6
    • 79961146280 scopus 로고    scopus 로고
    • Increasing gout prevalence in the US over the last two decades: The national health and nutrition examination survey (NHANES)
    • Nov 7-11; Atlanta (GA)
    • Zhu Y, Pandya B, Choi H. Increasing gout prevalence in the US over the last two decades: the national health and nutrition examination survey (NHANES). 74th Annual Scientific Meeting of the American College of Rheumatology, 2010 Nov 7-11; Atlanta (GA).
    • (2010) 74th Annual Scientific Meeting of the American College of Rheumatology
    • Zhu, Y.1    Pandya, B.2    Choi, H.3
  • 7
    • 0036286849 scopus 로고    scopus 로고
    • The association between gout and nephrolithiasis: The National Health and Nutrition Examination Survey III, 1988-1994
    • DOI 10.1053/ajkd.2002.33911
    • Kramer HM, Curhan G. The association between gout and nephrolithiasis: the National Health and Nutrition Examination Survey III, 1988-1994. Am J Kidney Dis 2002; 40 (1): 37-42. (Pubitemid 34701209)
    • (2002) American Journal of Kidney Diseases , vol.40 , Issue.1 , pp. 37-42
    • Kramer, H.M.1    Curhan, G.2
  • 8
    • 3442899325 scopus 로고    scopus 로고
    • Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population
    • Wallace KL, Riedel AA, Joseph-Ridge N, et al. Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population. J Rheumatol 2004; 31 (8): 1582-7. (Pubitemid 39006641)
    • (2004) Journal of Rheumatology , vol.31 , Issue.8 , pp. 1582-1587
    • Wallace, K.L.1    Riedel, A.A.2    Joseph-Ridge, N.3    Wortmann, R.4
  • 10
    • 0029095028 scopus 로고
    • The prevalence and prophylaxis of gout in England
    • Harris CM, Lloyd DC, Lewis J. The prevalence and prophylaxis of gout in England. J Clin Epidemiol 1995; 48 (9): 1153-8.
    • (1995) J Clin Epidemiol , vol.48 , Issue.9 , pp. 1153-1158
    • Harris, C.M.1    Lloyd, D.C.2    Lewis, J.3
  • 11
    • 4043075471 scopus 로고    scopus 로고
    • Gout: On the brink of novel therapeutic options for an ancient disease
    • DOI 10.1002/art.20438
    • Bieber JD, Terkeltaub RA. Gout: on the brink of novel therapeutic options for an ancient disease. Arthritis Rheum 2004; 50 (8): 2400-14. (Pubitemid 39066263)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.8 , pp. 2400-2414
    • Bieber, J.D.1    Terkeltaub, R.A.2
  • 12
    • 10144245945 scopus 로고    scopus 로고
    • Prevalence of comorbid conditions and prescription medication use among patients with gout and hyperuricemia in a managed care setting
    • DOI 10.1097/01.rhu.0000147049.12220.32
    • Riedel AA, Nelson M, Wallace K, et al. Prevalence of comorbid conditions and prescription medication use among patients with gout and hyperuricemia in a managed care setting. J Clin Rheumatol 2004; 10 (6): 308-14. (Pubitemid 39614246)
    • (2004) Journal of Clinical Rheumatology , vol.10 , Issue.6 , pp. 308-314
    • Riedel, A.A.1    Nelson, M.2    Wallace, K.3    Joseph-Ridge, N.4    Cleary, M.5    Fam, A.G.6
  • 15
    • 65249143256 scopus 로고    scopus 로고
    • Adherence with urate-lowering therapies for the treatment of gout
    • Harrold LR, Andrade SE, Briesacher BA, et al. Adherence with urate-lowering therapies for the treatment of gout. Arthritis Res Ther 2009; 11 (2): R46.
    • (2009) Arthritis Res Ther , vol.11 , Issue.2
    • Harrold, L.R.1    Andrade, S.E.2    Briesacher, B.A.3
  • 16
    • 67650469666 scopus 로고    scopus 로고
    • Impact of noncompliance with urate-lowering drug on serum urate and gout-related healthcare costs: Administrative claims analysis
    • Halpern R, Mody RR, Fuldeore MJ, et al. Impact of noncompliance with urate-lowering drug on serum urate and gout-related healthcare costs: administrative claims analysis. Curr Med Res Opin 2009; 25 (7): 1711-9.
    • (2009) Curr Med Res Opin , vol.25 , Issue.7 , pp. 1711-1719
    • Halpern, R.1    Mody, R.R.2    Fuldeore, M.J.3
  • 17
    • 65249136104 scopus 로고    scopus 로고
    • Perceptions of disease and health-related quality of life among patients with gout
    • Lee SJ, Hirsch JD, Terkeltaub R, et al. Perceptions of disease and health-related quality of life among patients with gout. Rheumatology (Oxford) 2009; 48 (5): 582-6.
    • (2009) Rheumatology (Oxford) , vol.48 , Issue.5 , pp. 582-586
    • Lee, S.J.1    Hirsch, J.D.2    Terkeltaub, R.3
  • 19
    • 34548265240 scopus 로고    scopus 로고
    • Is gout associated with reduced quality of life? A case-control study
    • DOI 10.1093/rheumatology/kem150
    • Roddy E, Zhang W, Doherty M. Is gout associated with reduced quality of life? A case-control study. Rheumatology (Oxford) 2007; 46 (9): 1441-4. (Pubitemid 47317091)
    • (2007) Rheumatology , vol.46 , Issue.9 , pp. 1441-1444
    • Roddy, E.1    Zhang, W.2    Doherty, M.3
  • 20
    • 75749100094 scopus 로고    scopus 로고
    • Prescription and comorbidity screening following consultation for acute gout in primary care
    • Roddy E, Mallen CD, Hider SL, et al. Prescription and comorbidity screening following consultation for acute gout in primary care. Rheumatology (Oxford) 2010; 49 (1): 105-11.
    • (2010) Rheumatology (Oxford) , vol.49 , Issue.1 , pp. 105-111
    • Roddy, E.1    Mallen, C.D.2    Hider, S.L.3
  • 22
  • 23
    • 0031980641 scopus 로고    scopus 로고
    • Clinical presentation and disease associations of gout: A hospital-based study of 100 patients in Singapore
    • Koh WH, Seah A, Chai P. Clinical presentation and disease associations of gout: a hospital-based study of 100 patients in Singapore. Ann Acad Med Singapore 1998; 27 (1): 7-10.
    • (1998) Ann Acad Med Singapore , vol.27 , Issue.1 , pp. 7-10
    • Koh, W.H.1    Seah, A.2    Chai, P.3
  • 24
    • 79961150612 scopus 로고    scopus 로고
    • Clinical manifestations of treatment failure gout (TFG) in four independent cohorts [abstract]
    • Yood RA, Baraf HSB, Becker MA, et al. Clinical manifestations of treatment failure gout (TFG) in four independent cohorts [abstract]. Ann Rheum Dis 2009; 68 Suppl. 3: 323.
    • (2009) Ann Rheum Dis , vol.68 , Issue.SUPPL.3 , pp. 323
    • Yood, R.A.1    Baraf, H.S.B.2    Becker, M.A.3
  • 25
    • 67449099218 scopus 로고    scopus 로고
    • Quality of life and disability in patients with treatment-failure gout
    • Becker MA, Schumacher HR, Benjamin KL, et al. Quality of life and disability in patients with treatment-failure gout. J Rheumatol 2009; 36 (5): 1041-8.
    • (2009) J Rheumatol , vol.36 , Issue.5 , pp. 1041-1048
    • Becker, M.A.1    Schumacher, H.R.2    Benjamin, K.L.3
  • 27
    • 0026597399 scopus 로고
    • Diuretic induced gout: A multifactorial condition
    • Scott JT, Higgens CS. Diuretic induced gout: a multifactorial condition. Ann Rheum Dis 1992; 51 (2): 259-61.
    • (1992) Ann Rheum Dis , vol.51 , Issue.2 , pp. 259-261
    • Scott, J.T.1    Higgens, C.S.2
  • 28
    • 33846998296 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome in patients with gout: The Third National Health and Nutrition Examination Survey
    • Choi HK, Ford ES, Li C, et al. Prevalence of the metabolic syndrome in patients with gout: the Third National Health and Nutrition Examination Survey. Arthritis Rheum 2007; 57 (1): 109-15.
    • (2007) Arthritis Rheum , vol.57 , Issue.1 , pp. 109-115
    • Choi, H.K.1    Ford, E.S.2    Li, C.3
  • 29
    • 31544454981 scopus 로고    scopus 로고
    • The prevalence of metabolic syndrome in patients with gout: A multicenter study
    • Rho YH, Choi SJ, Lee YH, et al. The prevalence of metabolic syndrome in patients with gout: a multicenter study. J Korean Med Sci 2005; 20 (6): 1029-33.
    • (2005) J Korean Med Sci , vol.20 , Issue.6 , pp. 1029-1033
    • Rho, Y.H.1    Choi, S.J.2    Lee, Y.H.3
  • 30
    • 57149091788 scopus 로고    scopus 로고
    • Elevated uric acid increases the risk for kidney disease
    • Obermayr RP, Temml C, Gutjahr G, et al. Elevated uric acid increases the risk for kidney disease. J Am Soc Nephrol 2008; 19 (12): 2407-13.
    • (2008) J Am Soc Nephrol , vol.19 , Issue.12 , pp. 2407-2413
    • Obermayr, R.P.1    Temml, C.2    Gutjahr, G.3
  • 31
    • 79961150983 scopus 로고    scopus 로고
    • Prevalence and costs of gout in patients with chronic kidney disease in a privately insured population [abstract]
    • Rocca Rey LA. Prevalence and costs of gout in patients with chronic kidney disease in a privately insured population [abstract]. Arthritis Rheum 2007; 56 Suppl. 9: 89.
    • (2007) Arthritis Rheum , vol.56 , Issue.SUPPL.9 , pp. 89
    • Rocca Rey, L.A.1
  • 32
    • 50349101970 scopus 로고    scopus 로고
    • Gout is associated with more comorbidities, poorer health-related quality of life and higher healthcare utilisation in US veterans
    • Singh JA, Strand V. Gout is associated with more comorbidities, poorer health-related quality of life and higher healthcare utilisation in US veterans. Ann Rheum Dis 2008; 67 (9): 1310-6.
    • (2008) Ann Rheum Dis , vol.67 , Issue.9 , pp. 1310-1316
    • Singh, J.A.1    Strand, V.2
  • 33
    • 2442691780 scopus 로고    scopus 로고
    • 3 study
    • DOI 10.1136/ard.2003.010769
    • Picavet HS, Hoeymans N. Health related quality of life in multiple musculoskeletal diseases: SF-36 and EQ-5D in the DMC3 study. Ann Rheum Dis 2004; 63 (6): 723-9. (Pubitemid 38658404)
    • (2004) Annals of the Rheumatic Diseases , vol.63 , Issue.6 , pp. 723-729
    • Picavet, H.S.J.1    Hoeymans, N.2
  • 34
    • 49949152075 scopus 로고    scopus 로고
    • The disutility of chronic gout
    • Khanna D, Ahmed M, Yontz D, et al. The disutility of chronic gout. Qual Life Res 2008; 17 (5): 815-22.
    • (2008) Qual Life Res , vol.17 , Issue.5 , pp. 815-822
    • Khanna, D.1    Ahmed, M.2    Yontz, D.3
  • 35
    • 79961157144 scopus 로고    scopus 로고
    • Uratelowering therapy results in clinically important improvements in health-related quality of life-analysis from an academic clinical practice [abstract]
    • Khanna P, Perex-Ruiz F, Maranian P, et al. Uratelowering therapy results in clinically important improvements in health-related quality of life-analysis from an academic clinical practice [abstract]. Ann Rheum Dis 2010; 69 Suppl. 3: 717.
    • (2010) Ann Rheum Dis , vol.69 , Issue.SUPPL.3 , pp. 717
    • Khanna, P.1    Perex-Ruiz, F.2    Maranian, P.3
  • 36
    • 79954592926 scopus 로고    scopus 로고
    • Health-related quality-of-life (HRQOL) of patients with treatment failure gout (TFG) is poor, and comparable to that in other severe chronic conditions [abstract]
    • Strand V, Edwards L, Singh JA.Health-related quality-of-life (HRQOL) of patients with treatment failure gout (TFG) is poor, and comparable to that in other severe chronic conditions [abstract]. Ann Rheum Dis 2009; 68 Suppl. 3: 168.
    • (2009) Ann Rheum Dis , vol.68 , Issue.SUPPL.3 , pp. 168
    • Strand, V.1    Edwards, L.2    Singh, J.A.3
  • 37
    • 79961136128 scopus 로고    scopus 로고
    • Improvement in health-related quality of life (HRQOL) in patients with treatment failure gout (TFG) treated with pegloticase measured by SF-6D derived utility [abstract]
    • Strand V, Edwards NL, Baraf HSB, et al. Improvement in health-related quality of life (HRQOL) in patients with treatment failure gout (TFG) treated with pegloticase measured by SF-6D derived utility [abstract]. Arthritis Rheum 2009; 60 Suppl. 10: 1101.
    • (2009) Arthritis Rheum , vol.60 , Issue.SUPPL.10 , pp. 1101
    • Strand, V.1    Edwards, N.L.2    Baraf, H.S.B.3
  • 38
    • 79953094557 scopus 로고    scopus 로고
    • Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat gouty arthritis by suppressing inflammation: Results of a randomized dose-ranging study
    • Schlesinger N, De Meulemeester M, Pikhlak A, et al. Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat gouty arthritis by suppressing inflammation: results of a randomized, dose-ranging study. Arthritis Res Ther 2011; 13 (2): R53.
    • (2011) Arthritis Res Ther , vol.13 , Issue.2
    • Schlesinger, N.1    De Meulemeester, M.2    Pikhlak, A.3
  • 39
    • 38049001645 scopus 로고    scopus 로고
    • Improved health-related quality of life with effective disease-modifying antirheumatic drugs: Evidence from randomized controlled trials
    • Strand V, Singh JA. Improved health-related quality of life with effective disease-modifying antirheumatic drugs: evidence from randomized controlled trials. Am J Manag Care 2007; 13 Suppl. 9: 237-51.
    • (2007) Am J Manag Care , vol.13 , Issue.SUPPL.9 , pp. 237-251
    • Strand, V.1    Singh, J.A.2
  • 40
    • 79251505293 scopus 로고    scopus 로고
    • Systemic lupus erythematosus (SLE) impacts all domains of health-related quality of life (HRQOL): Baseline results from five randomized controlled trials (RCTs) [abstract]
    • Strand V, Petri M, Buyon J, et al. Systemic lupus erythematosus (SLE) impacts all domains of health-related quality of life (HRQOL): baseline results from five randomized controlled trials (RCTs) [abstract]. Ann Rheum Dis 2007; 66 Suppl. 2: 482.
    • (2007) Ann Rheum Dis , vol.66 , Issue.SUPPL.2 , pp. 482
    • Strand, V.1    Petri, M.2    Buyon, J.3
  • 41
    • 34548610974 scopus 로고    scopus 로고
    • Health-related quality of life of heart failure and coronary artery disease patients improved during participation in disease management programs: A longitudinal observational study
    • DOI 10.1089/dis.2007.103612
    • Martin M, Blaisdell-Gross B, Fortin EW, et al. Healthrelated quality of life of heart failure and coronary artery disease patients improved during participation in disease management programs: a longitudinal observational study. Dis Manag 2007; 10 (3): 164-78. (Pubitemid 47400547)
    • (2007) Disease Management , vol.10 , Issue.3 , pp. 164-178
    • Martin, M.1    Blaisdell-Gross, B.2    Fortin, E.W.3    Maruish, M.E.4    Manocchia, M.5    Sun, X.6    Walker, D.R.7    Apple, J.L.8    Ware Jr., J.E.9
  • 42
    • 34548449320 scopus 로고    scopus 로고
    • Physical functioning and mental well-being in association with health outcome in patients enrolled in the Multicenter Automatic Defibrillator Implantation Trial II
    • DOI 10.1093/eurheartj/ehl485
    • Piotrowicz K, Noyes K, Lyness JM, et al. Physical functioning and mental well-being in association with health outcome in patients enrolled in the Multicenter Automatic Defibrillator Implantation Trial II. Eur Heart J 2007; 28 (5): 601-7. (Pubitemid 47355502)
    • (2007) European Heart Journal , vol.28 , Issue.5 , pp. 601-607
    • Piotrowicz, K.1    Noyes, K.2    Lyness, J.M.3    McNitt, S.4    Andrews, M.L.5    Dick, A.6    Hall, W.J.7    Moss, A.J.8    Zareba, W.9
  • 44
    • 26444555573 scopus 로고    scopus 로고
    • Factors associated with musculoskeletal disability and chronic renal failure in clinically diagnosed primary gout
    • Alvarez-Nemegyei J, Cen-Piste JC, Medina-Escobedo M, et al. Factors associated with musculoskeletal disability and chronic renal failure in clinically diagnosed primary gout. J Rheumatol 2005; 32 (10): 1923-7. (Pubitemid 41430484)
    • (2005) Journal of Rheumatology , vol.32 , Issue.10 , pp. 1923-1927
    • Alvarez-Nemegyei, J.1    Cen-Piste, J.C.2    Medina-Escobedo, M.3    Villanueva-Jorge, S.4
  • 45
    • 79961144093 scopus 로고    scopus 로고
    • Rapid improvement in health-related quality of life (HRQoL) in gouty arthritis patients treated with canakinumab (ACZ885) compared to triamcinolone acetonide
    • Nov 7-11; Atlanta (GA)
    • So A, De Meulemeester M, Pikhlak A, et al. Rapid improvement in health-related quality of life (HRQoL) in gouty arthritis patients treated with canakinumab (ACZ885) compared to triamcinolone acetonide. 74th Annual Scientific Meeting of the American College of Rheumatology, 2010 Nov 7-11; Atlanta (GA).
    • (2010) 74th Annual Scientific Meeting of the American College of Rheumatology
    • So, A.1    De Meulemeester, M.2    Pikhlak, A.3
  • 47
    • 51849139524 scopus 로고    scopus 로고
    • Treatment-failure gout: A moving target
    • Edwards NL. Treatment-failure gout: a moving target. Arthritis Rheum 2008; 58 (9): 2587-90.
    • (2008) Arthritis Rheum , vol.58 , Issue.9 , pp. 2587-2590
    • Edwards, N.L.1
  • 49
    • 66149107433 scopus 로고    scopus 로고
    • Gout in the elderly: A population health study
    • Hanly JG, Skedgel C, Sketris I, et al. Gout in the elderly: a population health study. J Rheumatol 2009; 36 (4): 822-30.
    • (2009) J Rheumatol , vol.36 , Issue.4 , pp. 822-830
    • Hanly, J.G.1    Skedgel, C.2    Sketris, I.3
  • 50
    • 79961154661 scopus 로고    scopus 로고
    • The costs of treatment failure gout: A claims-based analysis [abstract]
    • Wu EQ, Yu AP, Guerin A, et al. The costs of treatment failure gout: a claims-based analysis [abstract]. Arthritis Rheum 2009; 60 Suppl. 10: 1112.
    • (2009) Arthritis Rheum , vol.60 , Issue.SUPPL.10 , pp. 1112
    • Wu, E.Q.1    Yu, A.P.2    Guerin, A.3
  • 51
    • 67449091361 scopus 로고    scopus 로고
    • Frequency, risk, and cost of gout-related episodes among the elderly: Does serum uric acid level matter?
    • Wu EQ, Patel PA,ModyRR, et al. Frequency, risk, and cost of gout-related episodes among the elderly: does serum uric acid level matter? J Rheumatol 2009; 36 (5): 1032-40.
    • (2009) J Rheumatol , vol.36 , Issue.5 , pp. 1032-1040
    • Wu, E.Q.1    Patel, P.A.2    Mody, R.R.3
  • 52
    • 67650339824 scopus 로고    scopus 로고
    • The effect of serum urate on gout flares and their associated costs: An administrative claims analysis
    • Halpern R, FuldeoreMJ,Mody RR, et al. The effect of serum urate on gout flares and their associated costs: an administrative claims analysis. J Clin Rheumatol 2009; 15 (1): 3-7.
    • (2009) J Clin Rheumatol , vol.15 , Issue.1 , pp. 3-7
    • Halpern, R.1    Fuldeore, M.J.2    Mody, R.R.3
  • 54
    • 2642527090 scopus 로고    scopus 로고
    • A retrospective study of the relationship between serum urate level and recurrent attacks of gouty arthritis: Evidence for reduction of recurrent gouty arthritis with antihyperuricemic therapy
    • Shoji A, Yamanaka H, Kamatani N. A retrospective study of the relationship between serum urate level and recurrent attacks of gouty arthritis: evidence for reduction of recurrent gouty arthritis with antihyperuricemic therapy. Arthritis Rheum 2004; 51 (3): 321-5. (Pubitemid 38725128)
    • (2004) Arthritis Care and Research , vol.51 , Issue.3 , pp. 321-325
    • Shoji, A.1    Yamanaka, H.2    Kamatani, N.3
  • 56
    • 8344222080 scopus 로고    scopus 로고
    • Management of acute and chronic gouty arthritis: Present state-of-the-art
    • DOI 10.2165/00003495-200464210-00003
    • Schlesinger N. Management of acute and chronic gouty arthritis: present state-of-the-art. Drugs 2004; 64 (21): 2399-416. (Pubitemid 39480701)
    • (2004) Drugs , vol.64 , Issue.21 , pp. 2399-2416
    • Schlesinger, N.1
  • 58
    • 34447558197 scopus 로고    scopus 로고
    • Treatment of acute gout in hospitalized patients
    • Petersel D, Schlesinger N. Treatment of acute gout in hospitalized patients. J Rheumatol 2007; 34 (7): 1566-8. (Pubitemid 47067996)
    • (2007) Journal of Rheumatology , vol.34 , Issue.7 , pp. 1566-1568
    • Petersel, D.1    Schlesinger, N.2
  • 59
    • 79961155593 scopus 로고    scopus 로고
    • Acute gout management during hospitalisation: A need for a protocol
    • Epub Jan 4
    • Gnanenthiran SR, Hassett GM, Gibson KA, et al. Acute gout management during hospitalisation: a need for a protocol. Intern Med J. Epub 2010 Jan 4.
    • (2010) Intern Med J.
    • Gnanenthiran, S.R.1    Hassett, G.M.2    Gibson, K.A.3
  • 62
    • 33846799011 scopus 로고    scopus 로고
    • Therapeutic advances in gout
    • DOI 10.1097/BOR.0b013e32802106b9, PII 0000228120070300000008
    • Pascual E, Sivera F. Therapeutic advances in gout. Curr Opin Rheumatol 2007; 19 (2): 122-7. (Pubitemid 46208769)
    • (2007) Current Opinion in Rheumatology , vol.19 , Issue.2 , pp. 122-127
    • Pascual, E.1    Sivera, F.2
  • 64
    • 68249114476 scopus 로고    scopus 로고
    • Panel on the pharmacological mangement of persistent pain in older persons
    • American Geriatric Society
    • American Geriatric Society. Panel on the pharmacological mangement of persistent pain in older persons. J Am Geriatr Soci 2009; 57: 1331-46.
    • (2009) J Am Geriatr Soci , vol.57 , pp. 1331-1346
  • 65
    • 33846403715 scopus 로고    scopus 로고
    • Management of gout in older adults: Barriers to optimal control
    • DOI 10.2165/00002512-200724010-00002
    • Hoskison KT, Wortmann RL. Management of gout in older adults: barriers to optimal control. Drugs Aging 2007; 24 (1): 21-36. (Pubitemid 46148079)
    • (2007) Drugs and Aging , vol.24 , Issue.1 , pp. 21-36
    • Hoskison, K.T.1    Wortmann, R.L.2
  • 67
    • 0008553199 scopus 로고
    • Nonsteroidal anti-inflammatory drugs; Nonopioid analgesics; Drugs used in gout
    • Katzung BG editor Norwalk: Apleton and Lange
    • Katzung BG. Nonsteroidal anti-inflammatory drugs; nonopioid analgesics; drugs used in gout. In: Katzung BG, editor. Basic and clinical pharmacology. Norwalk: Apleton and Lange, 1995: 536-59.
    • (1995) Basic and Clinical Pharmacology , pp. 536-559
    • Katzung, B.G.1
  • 68
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • DOI 10.1038/nature04516, PII N04516
    • Martinon F, Petrilli V, Mayor A, et al. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440 (7081): 237-41. (Pubitemid 43372104)
    • (2006) Nature , vol.440 , Issue.7081 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 69
    • 77950525312 scopus 로고    scopus 로고
    • High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter randomized double-blind placebo-controlled parallelgroup dose-comparison colchicine study
    • Terkeltaub RA, Furst DE, Bennett K, et al. High versus low dosing of oral colchicine for early acute gout flare: twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallelgroup, dose-comparison colchicine study. Arthritis Rheum 2010; 62 (4): 1060-8.
    • (2010) Arthritis Rheum , vol.62 , Issue.4 , pp. 1060-1068
    • Terkeltaub, R.A.1    Furst, D.E.2    Bennett, K.3
  • 72
    • 0016201345 scopus 로고
    • Prophylactic colchicine therapy of intercritical gout: A placebocontrolled study of probenecid-treated patients
    • Paulus HE, Schlosstein LH, Godfrey RG, et al. Prophylactic colchicine therapy of intercritical gout: a placebocontrolled study of probenecid-treated patients. Arthritis Rheum 1974; 17 (5): 609-14.
    • (1974) Arthritis Rheum , vol.17 , Issue.5 , pp. 609-614
    • Paulus, H.E.1    Schlosstein, L.H.2    Godfrey, R.G.3
  • 74
    • 44349087738 scopus 로고    scopus 로고
    • Use of oral prednisolone or naproxen for the treatment of gout arthritis: A double-blind, randomised equivalence trial
    • DOI 10.1016/S0140-6736(08)60799-0, PII S0140673608607990
    • Janssens HJ, Janssen M, van de Lisdonk EH, et al. Use of oral prednisolone or naproxen for the treatment of gout arthritis: a double-blind, randomised equivalence trial. Lancet 2008; 371 (9627): 1854-60. (Pubitemid 351736009)
    • (2008) The Lancet , vol.371 , Issue.9627 , pp. 1854-1860
    • Janssens, H.J.1    Janssen, M.2    Van De Lisdonk, E.H.3    Van Riel, P.L.4    Van Weel, C.5
  • 75
    • 0027417910 scopus 로고
    • Comparison of triamcinolone acetonide with indomethacin in the treatment of acute gouty arthritis
    • Alloway JA, Moriarty MJ, Hoogland YT, et al. Comparison of triamcinolone acetonide with indomethacin in the treatment of acute gouty arthritis. J Rheumatol 1993; 20 (1): 111-3. (Pubitemid 23049192)
    • (1993) Journal of Rheumatology , vol.20 , Issue.1 , pp. 111-113
    • Alloway, J.A.1    Moriarty, M.J.2    Hoogland, Y.T.3    Nashel, D.J.4
  • 76
    • 0028133477 scopus 로고
    • Comparison of adrenocorticotropic hormone and triamcinolone acetonide in the treatment of acute gouty arthritis
    • Siegel LB, Alloway JA, Nashel DJ. Comparison of adrenocorticotropic hormone and triamcinolone acetonide in the treatment of acute gouty arthritis. J Rheumatol 1994; 21 (7): 1325-7. (Pubitemid 24234673)
    • (1994) Journal of Rheumatology , vol.21 , Issue.7 , pp. 1325-1327
    • Siegel, L.B.1    Alloway, J.A.2    Nashel, D.J.3
  • 77
    • 77957688721 scopus 로고    scopus 로고
    • Canakinumab for treatment of acute flares in refractory gouty arthritis
    • So A, De Meulemeester M, Pikhlak A, et al. Canakinumab for treatment of acute flares in refractory gouty arthritis. Arthritis Rheum 2010; 62 (10): 3064-74.
    • (2010) Arthritis Rheum , vol.62 , Issue.10 , pp. 3064-3074
    • So, A.1    De Meulemeester, M.2    Pikhlak, A.3
  • 78
    • 0032853025 scopus 로고    scopus 로고
    • Treatment of acute attacks of gout with a small dose of intraarticular triamcinolone acetonide [6]
    • Fernandez C, Noguera R, Gonzalez JA, et al. Treatment of acute attacks of gout with a small dose of intraarticular triamcinolone acetonide. J Rheumatol 1999; 26 (10): 2285-6. (Pubitemid 29487039)
    • (1999) Journal of Rheumatology , vol.26 , Issue.10 , pp. 2285-2286
    • Fernandez, C.1    Noguera, R.2    Gonzalez, J.A.3    Pascual, E.4
  • 79
    • 65849231192 scopus 로고    scopus 로고
    • Treating to target: A strategy to cure gout
    • Perez-Ruiz F. Treating to target: a strategy to cure gout. Rheumatology (Oxford) 2009; 48 Suppl. 2: ii9-14.
    • (2009) Rheumatology (Oxford) , vol.48 , Issue.SUPPL.2
    • Perez-Ruiz, F.1
  • 80
    • 34250724118 scopus 로고    scopus 로고
    • Lowering serum uric acid levels: What is the optimal target for improving clinical outcomes in gout?
    • DOI 10.1002/art.23007
    • Perez-Ruiz F, Liote F. Lowering serum uric acid levels: what is the optimal target for improving clinical outcomes in gout? Arthritis Rheum 2007; 57 (7): 1324-8. (Pubitemid 47585481)
    • (2007) Arthritis Care and Research , vol.57 , Issue.7 , pp. 1324-1328
    • Perez-Ruiz, F.1    Liote, F.2
  • 82
    • 77953729446 scopus 로고    scopus 로고
    • The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: The CONFIRMS trial
    • Becker MA, Schumacher HR, Espinoza LR, et al. The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. Arthritis Res Ther 2010; 12 (2): R63.
    • (2010) Arthritis Res Ther , vol.12 , Issue.2
    • Becker, M.A.1    Schumacher, H.R.2    Espinoza, L.R.3
  • 83
    • 56049101851 scopus 로고    scopus 로고
    • Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: A 28-week phase III randomized double-blind parallel-group trial
    • Schumacher Jr HR, Becker MA, Wortmann RL, et al. Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial. Arthritis Rheum2008; 59 (11): 1540-8.
    • (2008) Arthritis Rheum , vol.59 , Issue.11 , pp. 1540-1548
    • Schumacher Jr., H.R.1    Becker, M.A.2    Wortmann, R.L.3
  • 84
  • 86
    • 34848884310 scopus 로고    scopus 로고
    • Concordance of the management of chronic gout in a UK primary-care population with the EULAR gout recommendations
    • DOI 10.1136/ard.2007.070755
    • Roddy E, Zhang W, Doherty M. Concordance of the management of chronic gout in a UK primary-care population with the EULAR gout recommendations. Ann Rheum Dis 2007; 66 (10): 1311-5. (Pubitemid 47492473)
    • (2007) Annals of the Rheumatic Diseases , vol.66 , Issue.10 , pp. 1311-1315
    • Roddy, E.1    Zhang, W.2    Doherty, M.3
  • 88
    • 3442887684 scopus 로고    scopus 로고
    • Compliance with allopurinol therapy among managed care enrollees with gout: A retrospective analysis of administrative claims
    • Riedel AA, Nelson M, Joseph-Ridge N, et al. Compliance with allopurinol therapy among managed care enrollees with gout: a retrospective analysis of administrative claims. J Rheumatol 2004; 31 (8): 1575-81. (Pubitemid 39006640)
    • (2004) Journal of Rheumatology , vol.31 , Issue.8 , pp. 1575-1581
    • Riedel, A.A.1    Nelson, M.2    Joseph-Ridge, N.3    Wallace, K.4    MacDonald, P.5    Becker, M.6
  • 89
    • 10344222996 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of febuxostat (TMX-67), a non-purine selective inhibitor of xanthine oxidase/xanthine dehydrogenase (NPSIXO) in patients with gout and/or hyperuricemia
    • DOI 10.1081/NCN-200027381
    • Komoriya K, Hoshide S, Takeda K, et al. Pharmacokinetics and pharmacodynamics of febuxostat (TMX-67), a non-purine selective inhibitor of xanthine oxidase/xanthine dehydrogenase (NPSIXO) in patients with gout and/or hyperuricemia. Nucleosides Nucleotides Nucleic Acids 2004; 23 (8-9): 1119-22. (Pubitemid 39625879)
    • (2004) Nucleosides, Nucleotides and Nucleic Acids , vol.23 , Issue.8-9 , pp. 1119-1122
    • Komoriya, K.1    Hoshide, S.2    Takeda, K.3    Kobayashi, H.4    Kubo, J.5    Tsuchimoto, M.6    Nakachi, T.7    Yamanaka, H.8    Kamatani, N.9
  • 90
    • 74549190166 scopus 로고    scopus 로고
    • North Deerfield (IL): Takeda Pharmaceuticals America
    • ULORIC (Febuxostat) [package insert]. North Deerfield (IL): Takeda Pharmaceuticals America, 2009.
    • (2009) ULORIC (Febuxostat) [Package Insert]
  • 91
    • 79961143385 scopus 로고    scopus 로고
    • Risk factors for renal lithiasis during treatment with uricosuric drugs [abstract]
    • Perez-Ruiz F. Risk factors for renal lithiasis during treatment with uricosuric drugs [abstract]. Arthitis Rheum 2009; 60 (10): 1499.
    • (2009) Arthitis Rheum , vol.60 , Issue.10 , pp. 1499
    • Perez-Ruiz, F.1
  • 93
    • 0024233411 scopus 로고
    • Uricase protein sequences: Conserved during vertebrate evolution but absent in humans
    • Varela-Echavarria A, Montes de Oca-Luna R, Barrera-Saldana HA. Uricase protein sequences: conserved during vertebrate evolution but absent in humans. Faseb J 1988; 2 (15): 3092-6.
    • (1988) Faseb J , vol.2 , Issue.15 , pp. 3092-3096
    • Varela-Echavarria, A.1    Montes De Oca-Luna, R.2    Barrera-Saldana, H.A.3
  • 94
    • 79952360840 scopus 로고    scopus 로고
    • First application of computer-assisted analysis of digital photographs for assessing tophus response: Phase 3 studies of pegloticase in treatment failure gout [abstract]
    • Maroli AN, Waltrip R, AltonM, et al. First application of computer-assisted analysis of digital photographs for assessing tophus response: phase 3 studies of pegloticase in treatment failure gout [abstract]. Arthritis Rheum 2009; 60 Suppl. 10: 1111.
    • (2009) Arthritis Rheum , vol.60 , Issue.SUPPL.10 , pp. 1111
    • Maroli, A.N.1    Waltrip, R.2    Alton, M.3
  • 95
    • 78651098292 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous pegloticase (PGL) in treatment failure gout (TFG): Results from GOUT1 and GOUT2 [abstract]
    • Sundy JS, Baraf HSB, Becker MA, et al. Efficacy and safety of intravenous pegloticase (PGL) in treatment failure gout (TFG): results from GOUT1 and GOUT2 [abstract]. Ann Rheum Dis 2009; 68 Suppl. 3: 318.
    • (2009) Ann Rheum Dis , vol.68 , Issue.SUPPL.3 , pp. 318
    • Sundy, J.S.1    Baraf, H.S.B.2    Becker, M.A.3
  • 96
    • 84856620540 scopus 로고    scopus 로고
    • Savient Pharmaceuticals Ltd [Accessed 2011 Jun 27]
    • Savient Pharmaceuticals Ltd. KrystexxaTM (pegloticase): prescribing information [online]. Available from URL: www.krystexxa.com/pdfs/ KRYSTEXXAPrescribing-Infor mation.pdf [Accessed 2011 Jun 27].
    • KrystexxaTM (Pegloticase): Prescribing Information [Online]
  • 98
    • 77953477599 scopus 로고    scopus 로고
    • Routine serum uric acid (SUA) monitoring predicts antibody-mediated loss of response and infusion reaction risk during pegloticase therapy [abstract]
    • WrightD, Sundy JS, Rosario-Jansen T. Routine serum uric acid (SUA) monitoring predicts antibody-mediated loss of response and infusion reaction risk during pegloticase therapy [abstract]. Arthritis Rheum 2009; 60 Suppl. 10: 1104.
    • (2009) Arthritis Rheum , vol.60 , Issue.SUPPL.10 , pp. 1104
    • Wright, D.1    Sundy, J.S.2    Rosario-Jansen, T.3
  • 99
    • 34047174085 scopus 로고    scopus 로고
    • A pilot study of IL-1 inhibition by anakinra in acute gout
    • So A, De Smedt T, Revaz S, et al. A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther 2007; 9 (2): R28.
    • (2007) Arthritis Res Ther , vol.9 , Issue.2
    • So, A.1    De Smedt, T.2    Revaz, S.3
  • 100
    • 79961132107 scopus 로고    scopus 로고
    • The safety and efficacy of Anakinra in the treatment of acute gout in hospitalized patients [abstract]
    • Cho M, Ghosh P, Hans G, et al. The safety and efficacy of Anakinra in the treatment of acute gout in hospitalized patients [abstract]. Arthritis Rheum 2010; 60 Suppl. 9: 163.
    • (2010) Arthritis Rheum , vol.60 , Issue.SUPPL.9 , pp. 163
    • Cho, M.1    Ghosh, P.2    Hans, G.3
  • 101
    • 70349402166 scopus 로고    scopus 로고
    • The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: Results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study
    • Terkeltaub R, Sundy JS, Schumacher HR, et al. The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study. Ann Rheum Dis 2009; 68 (10): 1613-7.
    • (2009) Ann Rheum Dis , vol.68 , Issue.10 , pp. 1613-1617
    • Terkeltaub, R.1    Sundy, J.S.2    Schumacher, H.R.3
  • 102
    • 79957646006 scopus 로고    scopus 로고
    • Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: Results of a double-blind randomised study
    • Schlesinger N, Mysler E, Lin HY, et al. Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study. Ann Rheum Dis 2011; 70 (7): 1264-71.
    • (2011) Ann Rheum Dis , vol.70 , Issue.7 , pp. 1264-1271
    • Schlesinger, N.1    Mysler, E.2    Lin, H.Y.3
  • 103
    • 77957675498 scopus 로고    scopus 로고
    • Placebocontrolled study of rilonacept for prevention of gout flares during initiation of urate-lowering therapy [abstract]
    • Schumacher RH, Sundy JS, Terkeltaub R, et al. Placebocontrolled study of rilonacept for prevention of gout flares during initiation of urate-lowering therapy [abstract]. Ann Rheum Dis 2009; 68 Suppl. 3: 680.
    • (2009) Ann Rheum Dis , vol.68 , Issue.SUPPL.3 , pp. 680
    • Schumacher, R.H.1    Sundy, J.S.2    Terkeltaub, R.3
  • 104
    • 79961161465 scopus 로고    scopus 로고
    • Efficacy and safety of a range of doses of RDEA594, a novel uricosuric agent, as a single agent in hyperuricemic gout patients: Multicenter, randomized, double-blind, placebo-controlled, phase 2 experience [abstract]
    • Perez-Ruiz F, Hingorani V, Welp J, et al. Efficacy and safety of a range of doses of RDEA594, a novel uricosuric agent, as a single agent in hyperuricemic gout patients: multicenter, randomized, double-blind, placebo-controlled, phase 2 experience [abstract]. Ann Rheum Dis 2010; 69 Suppl. 3: 121.
    • (2010) Ann Rheum Dis , vol.69 , Issue.SUPPL.3 , pp. 121
    • Perez-Ruiz, F.1    Hingorani, V.2    Welp, J.3
  • 105
    • 79961142035 scopus 로고    scopus 로고
    • Tranilast, a novel, potential treatment for the chronic management of hyperuricemia in patients with gout, reduces serum uric acid (SUA) in healthy subjects [abstract]
    • Sundy JS, Kitt M. Tranilast, a novel, potential treatment for the chronic management of hyperuricemia in patients with gout, reduces serum uric acid (SUA) in healthy subjects [abstract]. Ann Rheum Dis 2010; 69 Suppl. 3: 607.
    • (2010) Ann Rheum Dis , vol.69 , Issue.SUPPL. 3 , pp. 607
    • Sundy, J.S.1    Kitt, M.2
  • 106
    • 79961146278 scopus 로고    scopus 로고
    • Effects of a purine nucleoside phosphorylase inhibitor, BCX4208, on the serum uric acid concentrations in patients with gout
    • Nov 7-11; Atlanta (GA)
    • Fitz-Patrick D, Drummond W, Pappas J, et al. Effects of a purine nucleoside phosphorylase inhibitor, BCX4208, on the serum uric acid concentrations in patients with gout. 74th Annual Scientific Meeting of the American College of Rheumatology, 2010 Nov 7-11; Atlanta (GA).
    • (2010) 74th Annual Scientific Meeting of the American College of Rheumatology
    • Fitz-Patrick, D.1    Drummond, W.2    Pappas, J.3
  • 107
    • 38049083888 scopus 로고    scopus 로고
    • Primer: Inflammasomes and interleukin 1beta in inflammatory disorders
    • Church LD, Cook GP, McDermott MF. Primer: inflammasomes and interleukin 1beta in inflammatory disorders. Nat Clin Pract Rheumatol 2008; 4 (1): 34-42.
    • (2008) Nat Clin Pract Rheumatol , vol.4 , Issue.1 , pp. 34-42
    • Church, L.D.1    Cook, G.P.2    McDermott, M.F.3
  • 108
    • 54249085533 scopus 로고    scopus 로고
    • Developments in the scientific and clinical understanding of gout
    • So A. Developments in the scientific and clinical understanding of gout. Arthritis Res Ther 2008; 10 (5): 221.
    • (2008) Arthritis Res Ther , vol.10 , Issue.5 , pp. 221
    • So, A.1
  • 109
    • 18644374105 scopus 로고    scopus 로고
    • Blocking IL-1 in systemic inflammation
    • DOI 10.1084/jem.20050640
    • Dinarello CA. Blocking IL-1 in systemic inflammation. J Exp Med 2005; 201 (9): 1355-9. (Pubitemid 40664079)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.9 , pp. 1355-1359
    • Dinarello, C.A.1
  • 110
    • 49449100184 scopus 로고    scopus 로고
    • Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblastmediated pathologic bone resorption
    • Tunyogi-Csapo M, Kis-Toth K, Radacs M, et al. Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblastmediated pathologic bone resorption. Arthritis Rheum 2008; 58 (8): 2397-408.
    • (2008) Arthritis Rheum , vol.58 , Issue.8 , pp. 2397-2408
    • Tunyogi-Csapo, M.1    Kis-Toth, K.2    Radacs, M.3
  • 111
    • 68149163293 scopus 로고    scopus 로고
    • The mechanism of osteoclast differentiation induced by IL-1
    • Kim JH, Jin HM, Kim K, et al. The mechanism of osteoclast differentiation induced by IL-1. J Immunol 2009; 183 (3): 1862-70.
    • (2009) J Immunol , vol.183 , Issue.3 , pp. 1862-1870
    • Kim, J.H.1    Jin, H.M.2    Kim, K.3
  • 113
    • 63449105836 scopus 로고    scopus 로고
    • Rilonacept (Arcalyst), an interleukin-1 trap for the treatment of cryopyrin-associated periodic syndromes
    • Kapur S, Bonk ME. Rilonacept (Arcalyst), an interleukin-1 trap for the treatment of cryopyrin-associated periodic syndromes. Pharm Ther 2009; 34 (3): 138-41.
    • (2009) Pharm Ther , vol.34 , Issue.3 , pp. 138-141
    • Kapur, S.1    Bonk, M.E.2
  • 114
    • 46149100545 scopus 로고    scopus 로고
    • The human anti-IL-1 beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis
    • Alten R, Gram H, Joosten LA, et al. The human anti-IL-1 beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis. Arthritis Res Ther 2008; 10 (3): R67.
    • (2008) Arthritis Res Ther , vol.10 , Issue.3
    • Alten, R.1    Gram, H.2    Joosten, L.A.3
  • 115
    • 70349402166 scopus 로고    scopus 로고
    • The IL-1 inhibitor rilonacept in treatment of chronic gouty arthritis: Results of a placebo-controlled, monosequence crossover, nonrandomized, single-blind pilot study
    • Terkeltaub R, Sundy JS, Schumacher HR, et al. The IL-1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, nonrandomized, single-blind pilot study. Ann Rheum Dis 2009; 68 (10): 1613-7.
    • (2009) Ann Rheum Dis , vol.68 , Issue.10 , pp. 1613-1617
    • Terkeltaub, R.1    Sundy, J.S.2    Schumacher, H.R.3
  • 116
    • 77957675505 scopus 로고    scopus 로고
    • IL-1 antagonism in acute gout: Is targeting a single cytokine the answer?
    • Neogi T. IL-1 antagonism in acute gout: is targeting a single cytokine the answer? Arthritis Rheum 2010; 62 (10): 2845-9.
    • (2010) Arthritis Rheum , vol.62 , Issue.10 , pp. 2845-2849
    • Neogi, T.1
  • 117
    • 4644275038 scopus 로고    scopus 로고
    • Serum uric acid-lowering therapies: Where are we heading in management of hyperuricemia and the potential role of uricase
    • Bomalaski JS, Clark MA. Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase. Curr Rheumatol Rep 2004; 6 (3): 240-7.
    • (2004) Curr Rheumatol Rep , vol.6 , Issue.3 , pp. 240-247
    • Bomalaski, J.S.1    Clark, M.A.2
  • 118
    • 0036735357 scopus 로고    scopus 로고
    • Uricase formulated with polyethylene glycol (Uricase-PEG 20): Biochemical rationale and preclinical studies
    • Bomalaski JS, Holtsberg FW, Ensor CM, et al. Uricase formulated with polyethylene glycol (uricase-PEG 20): biochemical rationale and preclinical studies. J Rheumatol 2002; 29 (9): 1942-9. (Pubitemid 34988704)
    • (2002) Journal of Rheumatology , vol.29 , Issue.9 , pp. 1942-1949
    • Bomalaski, J.S.1    Holtsberg, F.W.2    Ensor, C.M.3    Clark, M.A.4
  • 119
    • 77957274432 scopus 로고    scopus 로고
    • Hyperuricaemia and gout: State of the art and future perspectives
    • DalbethN, SoA.Hyperuricaemia and gout: state of the art and future perspectives. Ann Rheum Dis 2010; 69 (10): 1738-43.
    • (2010) Ann Rheum Dis , vol.69 , Issue.10 , pp. 1738-1743
    • Dalbeth, N.1    So, A.2
  • 121
    • 84856594517 scopus 로고    scopus 로고
    • Ardea Biosciences Inc US National Institutes of Health ClinicalTrials.gov [online] [Accessed 2011 Jun 27]
    • Ardea Biosciences, Inc. Allopurinol combination study (RDEA594-203) [ClinicalTrials.gov identifierNCT01001338]. US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL: http://www.clinicaltrials.gov [Accessed 2011 Jun 27].
    • Allopurinol Combination Study (RDEA594-203) [ClinicalTrials.gov identifierNCT01001338]
  • 123
    • 79961132452 scopus 로고    scopus 로고
    • Tranilast suppresses inflammation induced by monosodium urate (MSU) crystals in vivo [abstract]
    • Serafini TA, Emerling DE. Tranilast suppresses inflammation induced by monosodium urate (MSU) crystals in vivo [abstract]. Ann Rheum Dis 2010; 69 Suppl. 3: 664.
    • (2010) Ann Rheum Dis , vol.69 , Issue.SUPPL.3 , pp. 664
    • Serafini, T.A.1    Emerling, D.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.