Protein synthesis in the dendrite

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 357, Issue 1420, 2002, Pages 521-529

  Shao, Jun Tang ^a   Schuman, Erin M ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Dendrite; Messenger RNA; Neuron; Protein synthesis; Synapse; Synaptic plasticity

Indexed keywords

PROTEIN;

MESSENGER RNA; PROTEIN;

ANIMAL; DENDRITE; GENETICS; HUMAN; METABOLISM; POLYADENYLATION; PROTEIN SYNTHESIS; REVIEW; RNA TRANSPORT; SYNAPSE;

ANIMALS; DENDRITES; HUMANS; POLYADENYLATION; PROTEIN BIOSYNTHESIS; PROTEINS; RNA TRANSPORT; RNA, MESSENGER; SYNAPSES;

EID: 0037193242     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.2001.0887     Document Type: Article

References (95)

1. Dynamic visualization of local protein synthesis in hippocampal neurons
2. Metabotropic glutamate receptor-initiated translocation of protein kinase pg0rsk to polyribosomes: A possible factor regulating synaptic tranmission
3. 2+/calmodulin-dependent protein kinase II mRNA association to polysomes
4. Dendritic compartmentation of NMDA receptor mRNA in cultured hippocampal neurons
5. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation
6. Identification of a cis-acting dendritic targeting element in MAP2 mRNAs
7. A suggestive relationship of nerve cell RNA with specific synaptic sites
8. 2+/calmodulin-dependent protein kinase in developing rat brain
9. Protein synthesis requirement for the formation of synaptic elements
10. A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis
11. Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits
12. Molecular characterization of the dendritic growth cone: Regulated mRNA transport and local protein synthesis
13. The Mos pathway regulates cytoplasmic polyadenylation in Xenopus oocytes
14. Long-term potentiation in the hippocampal slice: Evidence for stimulated secretion of newly synthesized proteins
15. Dendritic spine changes associated with hippocampal long-term synaptic plasticity
16. Pairing the cholinergic agonist carbachol with patterned scaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic. NMDA-dependent mechanism
17. Synaptic tagging: Synapse specificity during protein-synthesis-dependent long-term potentiation
18. Synaptic tagging: Implications for late maintenance of hippocampal long-term potentiation
19. Anisomycin an inhibitor of protein synthesis blocks late phases of LTP phenomena in the hippocampal CA region in vitro
20. Dendritic and post-synaptic protein synthetic machinery
21. Selective localization of messenger RNA for cytoskeletal protein MAP2 in dendrites
22. Differential subcellular regulation of NMDAR1 protein and mRNA in dendrites of dentate gyrus granule cells after perforant path transection
23. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PBK) signaling pathway
24. Synaptic structure and development: Neuromuscular junction
25. Dendritic spines: Cellular specializations imparting both stability and flexibility to synaptic function
26. Glial contamination of synaptosomal fractions
27. Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression
28. Poly(A) metabolism and translation: The close-loop model
29. A requirement for local protein synthesis in neurotrophin-induced synaptic plasticity
30. The mammalian Staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: Implications for its involvement in mRNA transport
31. Synthesis and transport of newly formed proteins in dendrites of rat hippocampal pyramid cells. An electron microscope autoradiographic study
32. Inhibition of protein synthesis alters the subcellular distribution of mRNA in neurons but does not prevent dendritic transport of RNA
33. Neurotrophin-3 signals redistribute RNA in neurons
34. Translocation of RNA granules in living neurons
35. Microtubule-dependent recruitment of Staufen-green fluorescent protein into RNA-containing granules and subsequent dendritic transport in living hippocampal neurons
36. Cellular influences on RNA sorting in neurons and glia: An in situ hybridization histochemical study
37. Activity-induced enhancement of HB-GAM expression in rat hippocampal slices
38. Somatodendritic expression of an immediate early gene is regulated by synaptic activity
39. Arc, a growth factor and activity-regulated gene encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites
40. A human sequence homology of staufen is an RNA-binding protein that is associated with polysomes and localizes to the endoplasmic reticulum
41. Synapse-specific longterm facilitation of Aplysia sensory to motor synapses: A function for local protein synthesis in memory storage
42. Ultrastructural localization of dendritic messenger RNA in adult rat hippocampus
43. Origins and targets of translational control
44. The 3′-untranslated region of CAMKII-alpha is a cis-acting signal for the localization and translation of mRNA in dendrites
45. On the nature and differential distribution of mRNAs in hippocampal neurites: Implications for neuronal functioning
46. Two rat brain staufen isoforms differentially bind RNA
47. A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia
48. Two cis-acting elements in the 3′ untranslated region of alpha-CaMKII regulate its dendritic targeting
49. RNA transport in dendrites: A cis-acting targeting element is contained within neuronal BC1 RNA
50. Regulation of protein synthesis by calcium
51. Maintenance of late-phase LTP is accompanied by PKA-dependent increase in AMPA receptor synthesis
52. Protein synthesis-dependent formation of protein kinase M zeta in long-term potentiation
53. Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus
54. Tetanic stimulation leads to increased accumulation of Ca(2+)/calmodulin-dependent protein kinase II via dendritic protein synthesis in hippocampal neurons
55. Synaptogenetic mechanisms during chick cerebellar cortex development
56. Translocation machinery for synthesis of integral membrane and secretory proteins in dendritic spines
57. Evidence that protein constituents of postsynaptic membrane are locally synthesized: Analysis of proteins synthesized within synaptosomes
58. Metabotropic glutamate receptors trigger homosynaptic protein synthesis to prolong long-term potentiation
59. N-methyl-D-aspartate receptor activation and visual activity induce elongation factor-2 phosphorylation in amphibian tecta: A role for N-methyl-D-aspartate receptors in controlling protein synthesis
60. NMDA receptor-mediated control of protein synthesis at developing synapses
61. Coincident induction of long-term facilitation in Aplysia: Cooperativity between cell bodies and remote synapses
62. Postsynaptic translation affects the efficacy and morphology of neuromuscular junctions
63. Impaired spatial learning in α-calcium-calmodulin kinase II mutant mice
64. Deficient hippocampal long-term potentiation in α-calcium-calmodulin kinase II mutant mice
65. The mRNA 5′ cap-binding protein eIF-4E and control of cell growth
66. Three-dimensional analysis of dendritic spines. II. Spine apparatus and other cytoplasmic components
67. Blockade of long-term potentiation in rat hippocampal CA1 region by inhibitors of protein synthesis
68. Maskin is a CPEB-associated factor that transiently interacts with eIF-4E
69. Translational control during early development
70. Alterations in polyribosomes associated with dendritic spines during the reinnervation of the dentate gyrus of the adult rat
71. mRNA localization in neurons: A multipurpose mechanism?
72. Protein-synthetic machinery at postsynaptic sites during synaptogenesis: A quantitative study of the association between polyribosomes and developing synapses
73. Lamina-specific synaptic activation causes domain-specific alterations in dendritic immunostaining for MAP2 and CAM kinase II
74. Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus
75. Protein-synthesis machinery beneath postsynaptic sites on CNS neurons: Association between polyribosomes and other organelles at the synaptic site
76. Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites
77. Inactivation of glycogen synthase kinase-3 beta by phosphorylation: New kinase connections in insulin and growth-factor signalling
78. A role for a rat homolog of Staufen in the transport of RNA to neuronal dendrites
79. A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus
80. Translationally coupled degradation of mRNA in eukaryotes
81. Translational machinery in dendrites of hippocampal neurons in culture
82. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons
83. LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite
84. Demonstration of local protein synthesis within dendrites using a new cell culture system that permits the isolation of living axons and dendrites from their cell bodies
85. Long-term potentiation is associated with new excitatory spine synapses on rat dentate granule cells
86. 4E-BP1 phosphorylation is mediated by the FRAP-pT0s6k pathway and is independent of mitogen-activated protein kinase
87. Stimulated incorporation of amino acids into proteins of synaptosomal fractions induced by depolarizing treatments
88. Potassium ion stimulation triggers protein translation in synaptoneurosomal polyribosomes
89. Metabotropic glutamate receptors trigger postsynaptic protein synthesis
90. Synaptic synthesis of the fragile X protein: Possible involvement in synapse maturation and elimination
91. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
92. Regulation of initiation factor eIF-2B by GSK-3 regulated phosphorylation
93. Mammalian staufen is a double-stranded RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum
94. CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of α-CAMKII mRNA at synapses
95. Regulation and interaction of p90(rsk) isoforms with mitogen-activated protein kinases