Free-radical degradation of high-molecular-weight hyaluronan induced by ascorbate plus cupric ions. Testing of bucillamine and its SA981-metabolite as antioxidants

Journal of Pharmaceutical and Biomedical Analysis

Volumn 56, Issue 3, 2011, Pages 664-670

  Valachová, Katarína ^a   Hrabárová, Eva ^b   Priesolová, Elena ^c   Nagy, Milan ^c   Baňasová, Mária ^a   Juránek, Ivo ^a   Šoltés, Ladislav ^a  

^a INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

^c Physics and Informatics   (Slovakia)

Author keywords

ABTS and DPPH assays; Disease modifying anti rheumatic drugs; L Cysteine; Reactive oxygen species; Rotational viscometry

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 4,5,6,7 TETRAHYDRO 7,7 DIMETHYL 6 OXO 3H 1,2,5 DITHIAZEPINE 4 CARBOXYLIC ACID; ANTIOXIDANT; ASCORBIC ACID; BUCILLAMINE; CUPRIC ION; CYSTEINE; DISEASE MODIFYING ANTIRHEUMATIC DRUG; DRUG METABOLITE; FREE RADICAL; HYALURONIC ACID; PENICILLAMINE; SCAVENGER; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTHRITIS; ARTICLE; BIODEGRADATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DECOLORIZATION; DRUG STRUCTURE; IC 50; INHIBITION KINETICS; MOLECULAR WEIGHT; OXIDATIVE STRESS; PRIORITY JOURNAL; VISCOMETRY; VISCOSITY;

ANTIOXIDANTS; ANTIRHEUMATIC AGENTS; ASCORBIC ACID; CATIONS; COPPER; CYSTEINE; FREE RADICALS; HYALURONIC ACID; HYDROXYL RADICAL; MOLECULAR WEIGHT; OXIDATION-REDUCTION; PENICILLAMINE; PEROXIDES; VISCOSITY;

EID: 79961126785     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.06.015     Document Type: Article

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