Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

Biochemical Journal

Volumn 381, Issue 1, 2004, Pages 175-184

  Rees, Martin D ^a   Hawkins, Clare L ^a   Davies, Michael J ^a  

^a HEART RESEARCH INSTITUTE   (Australia)

Author keywords

Chloramide; Glycosaminoglycan; Hypochlorite; Myeloperoxidase; Radical; Superoxide

Indexed keywords

BIOCHEMISTRY; CATALYSIS; OXIDATION; POLYMERS; SULFUR COMPOUNDS; TRANSITION METALS;

HYPOCHLORITE; OXIDATIVE BURSTS; SUPEROXIDE RADICALS;

ENZYMES;

2 METHYL N NITROSOPROPANE; 5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; ALKANE DERIVATIVE; CHONDROITIN SULFATE; GLYCOSAMINOGLYCAN; HYALURONIC ACID; HYPOCHLORITE; METHIONINE; NITRITE; OXIDIZING AGENT; POLYMER; RADICAL; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; ELECTRON; ELECTRON SPIN RESONANCE; FRAGMENTATION REACTION; INFLAMMATION; METAL BINDING; MOLECULAR MECHANICS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; REACTION ANALYSIS;

CARBOHYDRATE SEQUENCE; CHLORAMINES; CHONDROITIN SULFATES; DRUG SYNERGISM; ELECTRON SPIN RESONANCE SPECTROSCOPY; GLYCOSAMINOGLYCANS; HYALURONIC ACID; HYPOCHLOROUS ACID; SPIN TRAPPING; SUPEROXIDES;

EID: 3142736372     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040148     Document Type: Article

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