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Volumn 76, Issue 15, 2011, Pages 6344-6349

General procedure for the synthesis of dinucleoside polyphosphates

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROCESS; DINUCLEOSIDE POLYPHOSPHATES; GENERAL APPROACH; METHYLIMIDAZOLIUM SALTS; POLYPHOSPHATES; TRIPHOSPHATE;

EID: 79961069237     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo200540e     Document Type: Article
Times cited : (36)

References (35)
  • 4
    • 0347093624 scopus 로고    scopus 로고
    • Compound 2, marketed as Diquas, has been approved in Japan for treating dry eye syndrome. See
    • Compound 2, marketed as Diquas, has been approved in Japan for treating dry eye syndrome. See: Fischbarq, J. Curr. Opin. Investig. Drugs 2003, 11, 1377
    • (2003) Curr. Opin. Investig. Drugs , vol.11 , pp. 1377
    • Fischbarq, J.1
  • 5
    • 0009910191 scopus 로고
    • AppA, the first 5′,5′-dinucleoside polyphosphate to be prepared, was constructed almost 60 years ago by Todd's group in a 17% yield by reacting 5′-AMP with trifluoroacetic anhydride overnight and evaporating to dryness. See
    • AppA, the first 5′,5′-dinucleoside polyphosphate to be prepared, was constructed almost 60 years ago by Todd's group in a 17% yield by reacting 5′-AMP with trifluoroacetic anhydride overnight and evaporating to dryness. See: Christie, S. M. H.; Elmore, D. T.; Kenner, G. W.; Todd, A. R.; Weymouth, F. J. J. Chem. Soc. London 1953, 2947
    • (1953) J. Chem. Soc. London , pp. 2947
    • Christie, S.M.H.1    Elmore, D.T.2    Kenner, G.W.3    Todd, A.R.4    Weymouth, F.J.5
  • 10
    • 0030810814 scopus 로고    scopus 로고
    • EDC has also been used in the preparation of an unsymmetrical dinucleoside triphosphate, albeit in low yield. See
    • EDC has also been used in the preparation of an unsymmetrical dinucleoside triphosphate, albeit in low yield. See: Zhang, F.-J.; Sih, C. J. Bioorg. Med. Chem. Lett. 1997, 7, 1753
    • (1997) Bioorg. Med. Chem. Lett. , vol.7 , pp. 1753
    • Zhang, F.-J.1    Sih, C.J.2
  • 17
    • 77952578243 scopus 로고    scopus 로고
    • For a brief review on the synthesis of dinucleoside 5′- pyrophosphates using 5′-phosphoimidazolides and a detailed description of their preparation using CDI, see
    • For a brief review on the synthesis of dinucleoside 5′- pyrophosphates using 5′-phosphoimidazolides and a detailed description of their preparation using CDI, see: Chen, L.; Rejman, D.; Pankiewicz, K. W.; Patterson, S. E. Curr. Protoc. Nucleic Acid Chem. 2005, 13.4.1
    • (2005) Curr. Protoc. Nucleic Acid Chem. , pp. 1341
    • Chen, L.1    Rejman, D.2    Pankiewicz, K.W.3    Patterson, S.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.