Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 30, 2011, Pages 12485-12490

  Barfod, Lea ^a,b   Dalgaard, Michael B ^a,b   Pleman, Suzan T ^a,b   Ofori, Michael F ^c   Pleass, Richard J ^d   Hviid, Lars ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Rigshospitalet   (Denmark)

^c University of Ghana   (Ghana)

^d LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

Evolutionary selection; Immunoevasion; Pregnancy; Sequestration

Indexed keywords

CHONDROITIN SULFATE; DUFFY BINDING PROTEIN; ERYTHROCYTE MEMBRANE PROTEIN 1; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY VAR2CSA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL SURFACE; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; HUMAN; HUMAN CELL; IMMUNITY; MALARIA FALCIPARUM; MALE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN;

ANTIBODIES, PROTOZOAN; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS, PROTOZOAN; EPITOPES; ERYTHROCYTE MEMBRANE; FEMALE; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALARIA, FALCIPARUM; PHAGOCYTOSIS; PLACENTA; PLASMODIUM FALCIPARUM; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; PROTOZOAN PROTEINS;

PLASMODIUM FALCIPARUM;

EID: 79961065929     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1103708108     Document Type: Article

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