Novel suppression mechanism operating in early phase of adipogenesis by positive feedback loop for enhancement of cyclooxygenase-2 expression through prostaglandin F2α receptor mediated activation of MEK/ERK-CREB cascade

FEBS Journal

Volumn 278, Issue 16, 2011, Pages 2901-2912

  Ueno, Toshiyuki ^a   Fujimori, Ko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

3T3 L1, PGF2 ; adipocytes; COX 2; CREB; MEK ERK

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 11 FLUORO 9,15 DIHYDROXY 15 (2 INDANYL) 16,17,18,19,20 PENTANORPROSTA 5,13 DIENOIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; FLUPROSTENOL; INDOMETACIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN F2 ALPHA; UNCLASSIFIED DRUG;

ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HORMONE ACTION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; PROSTAGLANDIN SYNTHESIS; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

3T3-L1 CELLS; ADIPOGENESIS; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLOOXYGENASE 2; DINOPROST; DINOPROSTONE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEEDBACK; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PPAR GAMMA; PROSTAGLANDINS F, SYNTHETIC; RECEPTORS, PROSTAGLANDIN; SIGNAL TRANSDUCTION;

EID: 79961023886     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08213.x     Document Type: Article

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