Prostanoid EP4 receptor is involved in suppression of 3T3-L1 adipocyte differentiation

Biochemical and Biophysical Research Communications

Volumn 322, Issue 3, 2004, Pages 1066-1072

  Tsuboi, Hiroaki ^a   Sugimoto, Yukihiko ^a   Kainoh, Takayuki ^a   Ichikawa, Atsushi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

Author keywords

Adipogenesis; Aspirin like drugs; Fat cell; Prostanoid; Receptor subtypes

Indexed keywords

AE 1329; AE 3208; BUCLADESINE; CYCLIC AMP; EP4 RECEPTOR; FLUPROSTENOL; INDOMETACIN; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; PROSTANOID RECEPTOR; RECEPTOR SUBTYPE; RESISTIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; MARKER GENE; MOLECULAR MIMICRY; MOUSE; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RNA ANALYSIS;

3T3 CELLS; ADIPOCYTES; ANIMALS; BUCLADESINE; CELL DIFFERENTIATION; DINOPROSTONE; GENE EXPRESSION REGULATION; MICE; PROSTAGLANDINS F, SYNTHETIC; RECEPTORS, PROSTAGLANDIN E; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 4444373075     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.018     Document Type: Article

References (33)

1. F.M. Gregoire, C.M. Smas, and H.S. Sul Understanding adipocyte differentiation Physiol. Rev. 78 1998 783 809
2. E.D. Rosen, and B.M. Spiegelman Molecular regulation of adipogenesis Annu. Rev. Cell Dev. Biol. 16 2001 145 171
3. P.B. Curtis-Prior Prostaglandins and obesity Lancet 1 1975 897 899
4. S. Kim, and N. Moustaid-Moussa Secretory, endocrine and autocrine/paracrine function of the adipocyte J. Nutr. 130 2000 3110S 3115S
5. J.N. Fain, L.R. Ballou, and S.W. Bahouth Obesity is induced in mice heterozygous for cyclooxygenase-2 Prostaglandins Other Lipid Mediat. 65 2001 199 209
6. R.A. Coleman, W.L. Smith, and S. Narumiya International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes Pharmacol. Rev. 46 1994 205 229
7. S. Narumiya, Y. Sugimoto, and F. Ushikubi Prostanoid receptors; structures, properties and functions Physiol. Rev. 79 1999 1193 1226
8. Y. Sugimoto, K. Hasumoto, T. Namba, A. Irie, M. Katsuyama, M. Negishi, A. Kakizuka, S. Narumiya, and A. Ichikawa Cloning and expression of a cDNA for mouse PGF receptor J. Biol. Chem. 269 1994 1356 1360
9. M. Negishi, Y. Sugimoto, and A. Ichikawa Prostaglandin E receptors J. Lipid Mediat. Cell Signalling 12 1995 379 391
10. Y. Sugimoto, S. Narumiya, and A. Ichikawa Distribution and function of prostanoid receptors: studies from knockout mice Prog. Lipid Res. 39 2000 289 314
11. T. Suzawa, C. Miyaura, M. Inada, T. Maruyama, Y. Sugimoto, F. Ushikubi, A. Ichikawa, S. Narumiya, and T. Suda The role of prostaglandin E receptor subtypes (EP1, EP2, EP3 and EP4) in bone resorption: an analysis using specific agonists for the respective EPs Endocrinology 141 2000 1554 1559
12. K. Yoshida, H. Oida, T. Kobayashi, T. Maruyama, M. Tanaka, T. Katayama, K. Yamaguchi, E. Segi, T. Tsuboyama, M. Matsushita, K. Ito, Y. Ito, Y. Sugimoto, F. Ushikubi, S. Ohuchida, K. Kondo, T. Nakamura, and S. Narumiya Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation Proc. Natl. Acad. Sci. USA 99 2002 4580 4585
13. K. Kabashima, T. Saji, T. Murata, M. Nagamachi, T. Matsuoka, E. Segi, K. Tsuboi, Y. Sugimoto, T. Kobayashi, Y. Miyachi, A. Ichikawa, and S. Narumiya The prostaglandin E receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut J. Clin. Invest. 109 2002 883 893
14. N. Hatae, K. Yamaoka, Y. Sugimoto, M. Negishi, and A. Ichikawa Augmentation of receptor-mediated adenylyl cyclase activity by Gi-coupled prostaglandin receptor subtype EP3 in a Gbetagamma subunit-independent manner Biochem. Biophys. Res. Commun. 290 2002 162 168
15. P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162 1987 156 159
16. E. Segi, K. Haraguchi, Y. Sugimoto, M. Tsuji, H. Tsunekawa, S. Tamba, K. Tsuboi, S. Tanaka, and A. Ichikawa Expression of messenger RNA for prostaglandin E receptor subtypes EP4/EP2 and cyclooxygenase isozymes in mouse periovulatory follicles and oviducts during superovulation Biol. Reprod. 68 2003 804 811
17. J.D. Borglum, S.B. Pedersen, G. Ailhaud, R. Negrel, and B. Richelsen Differential expression of prostaglandin receptor mRNAs during adipose cell differentiation Prostaglandins Other Lipid Mediat. 57 1999 305 317
18. C.M. Steppan, S.T. Bailey, S. Bhat, E.J. Brown, R.R. Banerjee, C.M. Wright, H.R. Patel, R.S. Ahima, and M.A. Lazar The hormone resistin links obesity to diabetes Nature 409 2001 292 293
19. O.A. MacDougald, and M.D. Lane Transcriptional regulation of gene expression during adipocyte differentiation Annu. Rev. Biochem. 64 1995 345 373
20. P. Tontonoz, E. Hu, and B.M. Spiegelman Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma Curr. Opin. Genet. Dev. 5 1995 571 576
21. P.D. Miles, Y. Barak, W. He, R.M. Evans, and J.M. Olefsky Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency J. Clin. Invest. 105 2000 287 292
22. C.W. Miller, D.A. Casimir, and J.M. Ntambi The mechanism of inhibition of 3T3-L1 preadipocyte differentiation by prostaglandin F2alpha Endocrinology 137 1996 5641 5650
23. D.A. Casimir, C.W. Miller, and J.M. Ntambi Preadipocyte differentiation blocked by prostaglandin stimulation of prostanoid FP2 receptor in murine 3T3-L1 cells Differentiation 60 1996 203 210
24. I.H. Williams, and S.E. Polakis Differentiation of 3T3-L1 fibroblasts to adipocytes. The effect of indomethacin, prostaglandin E1 and cyclic AMP on the process of differentiation Biochem. Biophys. Res. Commun. 77 1977 175 186
25. P. Verrando, R. Negrel, P. Grimaldi, M. Murphy, and G. Ailhaud Differentiation of ob 17 preadipocytes to adipocytes. Triggering effects of clofenapate and indomethacin Biochim. Biophys. Acta 663 1981 255 265
26. G. Vassaux, D. Gaillard, G. Ailhaud, and R. Negrel Prostacyclin is a specific effector of adipose cell differentiation. Its dual role as a cAMP- and Ca(2+)-elevating agent J. Biol. Chem. 267 1992 11092 11097
27. G. Vassaux, D. Gaillard, C. Darimont, G. Ailhaud, and R. Negrel Differential response of preadipocytes and adipocytes to prostacyclin and prostaglandin E2: physiological implications Endocrinology 131 1992 2393 2398
28. R.K. Petersen, C. Jorgensen, A.C. Rustan, L. Froyland, K. Muller-Decker, G. Furstenberger, R.K. Berge, K. Kristiansen, and L. Madsen Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases J. Lipid Res. 44 2003 2320 2330
29. D. Gaillard, R. Negrel, M. Lagarde, and G. Ailhaud Requirement and role of arachidonic acid in the differentiation of pre-adipose cells Biochem. J. 257 1989 389 397
30. B.T. Hyman, L.L. Stoll, and A.A. Spector Prostaglandin production by 3T3-L1 cells in culture Biochim. Biophys. Acta 713 1982 375 385
31. 2 increases the calcium concentration in rat brown adipocytes and their consumption of oxygen Prostaglandins 51 1996 377 386
32. H. Yan, A. Kermouni, M. Abdel-Hafez, and D.C. Lau Role of cyclooxygenases COX-1 and COX-2 in modulating adipogenesis in 3T3-L1 cells J. Lipid Res. 44 2003 424 429
33. T. Yokota, C.S. Meka, K.L. Medina, H. Igarashi, P.C. Comp, M. Takahashi, M. Nishida, K. Oritani, J. Miyagawa, T. Funahashi, Y. Tomiyama, Y. Matsuzawa, and P.W. Kincade Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins J. Clin. Invest. 109 2002 1303 1310