Activation of Src and transformation by an RPTPα splice mutant found in human tumours

EMBO Journal

Volumn 30, Issue 15, 2011, Pages 3200-3211

  Huang, Jian ^a   Yao, Ling ^a   Xu, Rongting ^a   Wu, Huacheng ^a   Wang, Min ^a   White, Brian S ^b   Shalloway, David ^b   Zheng, Xinmin ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

alternative splicing; cancer; protein tyrosine phosphatase; RPTPa; Src

Indexed keywords

COMPLEMENTARY DNA; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PROTEIN TYROSINE PHOSPHATASE; RECEPTOR PROTEIN TYROSINE PHOSPHATASE ALPHA; RECEPTOR PROTEIN TYROSINE PHOSPHATASE ALPHA245; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CARCINOGENESIS; CELL TRANSFORMATION; COLON TUMOR; CONTROLLED STUDY; DEPHOSPHORYLATION; DNA SEQUENCE; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER TUMOR; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SRC HOMOLOGY DOMAIN;

ANIMALS; DNA, COMPLEMENTARY; HUMANS; MICE; MICE, NUDE; MUTANT PROTEINS; PHOSPHORYLATION; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 4; SEQUENCE ANALYSIS, DNA; SRC-FAMILY KINASES; TRANSCRIPTIONAL ACTIVATION; TYROSINE;

MUS MUSCULUS; RODENTIA;

EID: 79961021621     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.212     Document Type: Article

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