Protein kinase D2 controls cardiac valve formation in zebrafish by regulating histone deacetylase 5 activity

Circulation

Volumn 124, Issue 3, 2011, Pages 324-334

  Just, Steffen ^a   Berger, Ina M ^a   Meder, Benjamin ^b   Backs, Johannes ^b   Keller, Andreas ^c   Marquart, Sabine ^b   Frese, Karen ^a,b   Patzel, Eva ^a   Rauch, Gerd Jörg ^b   Katus, Hugo A ^b   Rottbauer, Wolfgang ^a  

^a UNIVERSITY OF ULM   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

heart valves; histone deacetylase 5, human; protein kinase D2; Zebrafish

Indexed keywords

HISTONE DEACETYLASE 5; NOTCH RECEPTOR; PROTEIN KINASE; PROTEIN KINASE D2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BUNGEE GENE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENE MUTATION; HEART ATRIOVENTRICULAR VALVE; HEART VALVE; HUMAN; HUMAN CELL; MISSENSE MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ZEBRA FISH;

ANIMALS; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; HEART VALVES; HISTONE DEACETYLASES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MODELS, ANIMAL; MUTATION, MISSENSE; PROTEIN KINASES; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 79961021400     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.110.003301     Document Type: Article

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